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Measurements of the ionisation state of the intergalactic medium (IGM) can probe the sources of the extragalactic ionising background. We provide new measurements of the ionising emissivity of galaxies using measurements of the ionising background and ionising photon mean free path from high-redshift quasar spectra at $2.5 \lt z \lt 6$. Unlike most prior works, we account for radiative-transfer effects and possible neutral islands from the tail of reionisation at $z \gt 5$. We combine our results with measurements of the UV luminosity function to constrain the average escaping ionising efficiency of galaxies, $\langle f_{\textrm{esc}} \xi_{\textrm{ion}}\rangle_{L_{\textrm{UV}}}$. Assuming galaxies with $M_{\textrm{UV}} \lt -11$ emit ionising photons, we find $\log (\langle f_{\textrm{esc}} \xi_{\textrm{ion}}\rangle_{L_{\textrm{UV}}}/{\textrm {erg}^{-1}Hz}) = 24.47_{-0.17}^{+0.09}$ and $24.75_{-0.28}^{+0.15}$ at $z=5$ and 6, and $1\sigma$ upper limits of $24.48$ and $24.31$ at $z = 2.5$ and 4, respectively. We also estimate the population-averaged $f_{\textrm{esc}}$ using measurements of intrinsic ionising efficiency from JWST. We find $\langle f_{\textrm{esc}} \rangle = 0.126_{-0.041}^{+0.034}$ and $0.224_{-0.108}^{+0.098}$ at $z=5$ and 6, and $1\sigma$ upper limits of $f_{\textrm{esc}}\lt 0.138$ and $0.096$ at $z=2.5$ and 4, respectively, for $M_{\textrm{UV}} \lt -11$. Our findings are consistent with prior measurements of $f_{\textrm{esc}} \lesssim 10\%$ at $z \leq 4$, but indicate a factor of several increase between $z = 4$ and 6. The steepness of this evolution is sensitive to the highly uncertain mean free path and ionising background intensity at $z\gt5$. Lastly, we find $1.10^{+0.21}_{-0.39}$ photons per H atom are emitted into the IGM between $z=6$ and $=5.3$. This is $\approx 4\times$ more than needed to complete the last 20% of reionisation absent recombinations, suggesting that reionisation’s end was likely absorption-dominated.
The unchecked rise in global plastic production has resulted in widespread pollution and exposure to hazardous chemicals. Over 16,000 chemicals are used across the plastics life cycle, with thousands meeting criteria for persistence, bioaccumulation, mobility and toxicity. Many remain unregulated under existing multilateral environmental agreements. In response, the United Nations Environment Assembly has mandated the development of an international, legally binding instrument to end plastic pollution. Current treaty negotiations have begun addressing a short list of chemicals, yet significant gaps remain. These include insufficient regulatory mechanisms, lack of chemical transparency and reliance on ineffective recycling strategies that reintroduce toxic substances into consumer products. The presence of harmful chemicals in plastics contributes to major public health burdens and is an environmental threat, with high annual costs that reduce the potential for economic development through safer recycling. Vulnerable populations, including children, reproductive-aged individuals, and frontline communities, face heightened risks. To address this, we recommend the following three critical actions for the treaty: (1) globally regulating chemicals of concern based on hazard; (2) mandating transparency of plastic chemical composition and (3) designing plastics using safe-by-design principles and essential-use criteria. Group-based regulation, which would consider categories of related chemicals, should replace individual chemical approaches to prevent regrettable substitutions. Binding, global obligations, rather than fragmented or voluntary measures, are vital for sustainability, chemical safety, circularity and accountability across the plastics life cycle. A strong treaty is a critical opportunity to achieve a safer, more sustainable future for human and environmental health.
The Chinese Cultural Revolution reverberated the world over. As many scholars have shown, Maoism, an amorphous body of ideas originating from Chairman Mao Zedong, fed into different facets of the U.S. New Left, becoming one of the most powerful political forces in the 1960s. This article examines the fragmentation of U.S. Maoism in the 1970s to further illuminate the relationship between Mao’s China and its devout followers in the heartland of capitalism. As Sino-American “rapprochement” unfolded, U.S. Maoists travelled to China in droves to learn the essence of Mao’s revolution and replicate their own back home. They sought to build a united front party modeled after the Chinese Communist Party, while debating the “correct” line that their party should follow, an ideological altercation that fueled factional tension. Drawing on an array of U.S. and Chinese sources, this article argues that the quest for unity and struggle, the core tenet of Maoism, precipitated its downfall in the United States.
The connection between the drag and vorticity dynamics for viscous flow over a bluff body is explored using the Josephson–Anderson (J–A) relation for classical fluids. The instantaneous rate of work on the fluid, associated with the drag force, is related to the vorticity flux across the streamlines of a background potential flow. The vorticity transport itself is examined by aid of the Huggins vorticity-flux tensor. The analysis is performed for three flows: flow over a sphere at Reynolds numbers $Re=200,3700$, and flow over a prolate spheroid at $Re=3000$ and $20^{\circ }$ incidence. In these flows, the vorticity transport shifts the flow away from and towards the ideal potential flow, with a net balance towards the former effect thus making an appreciable contribution to the drag. The J–A relation is first demonstrated for the flow over a sphere at $Re=200$. The drag power injection is related to the viscous flux of azimuthal vorticity from the wall into the fluid, and the advection of vorticity by the detached shear layer. In the wake, the azimuthal vorticity is advected towards the wake centreline and is annihilated by viscous effects, which contributes a reduction in drag. The analysis of the flow over a sphere at $Re=3700$ is reported for the impulsively started and stationary stages, with emphasis on the effects of unsteady two-dimensional separation and turbulent transport in the transitional wake. The turbulent flux in the wake enhances the transport of mean azimuthal vorticity towards the wake centreline, and is the main driver of the recovery of enthalpy between the rear point of the sphere and far downstream. The rate of work on the fluid by the drag force for a prolate spheroid is mostly due to the transport of vorticity along the separated boundary layers. Primary and secondary separation contribute oppositely to the power injection by the drag force, while the large-scale vortices only re-distribute vorticity without a net contribution. A mechanism for secondary separation is proposed based on the theory of vortex-induced separation.
In recent years, Southern Thailand has witnessed an increase in surface planted with oil palm, driven primarily by smallholders who contribute over 90% of Thailand’s oil palm output. Despite their significant contribution, oil palm smallholders have consistently achieved lower yields compared to agro-industries, and limited research has been conducted to understand the limiting factors, such as management practices. Structured interviews were conducted to gather information about management practices and estimate the fresh fruit bunch yield in a network of 18 plantations in Krabi province, Thailand. A clustering approach, combining principal component analysis and hierarchical cluster analysis, was used to characterise the diversity of smallholder management practices. Four clusters of management practices were highlighted, characterised by varying intensities of fertiliser application (nitrogen, phosphorus, and potassium), mechanical versus chemical weeding, and harvest intervals. Notably, the farmers in our study applied less fertiliser, on average, than the recommendations of Thai Good Agricultural Practices. A significant portion of plots in the area (12 out of 18 plots) achieved good yields compared to attainable yields. A clear relationship between management practices and yield could however not be established. The large diversity of oil palm smallholders’ management practices and their performances highlighted in this study need to be better taken into account and understood in order to improve sustainability and foster certification schemes such as Roundtable on Sustainable Palm Oil (RSPO).
Alcohol misuse among women has risen compared to men. Women experience barriers to engaging in patient-centered comparative effectiveness research (CER) that, in turn, limits the evidence base for addressing alcohol misuse in this population. In this manuscript, we describe WomenWise, a community-partnered project and outline how we co-developed community focused CER training curriculum and collaboratively planned future partnered learning sessions (PLSs) with Community Advisory Board (CAB) feedback. Through this approach we aim to empower women to contribute to future patient-centered CER and enhance the stakeholder capacity for future patient-centered research.
Population is a key factor of national power. Declining fertility rates, especially in major economies, are reshaping global power dynamics by shrinking workforces amidst aging populations. In response, more nations are adopting techno-natalist policies, promoting reproductive technologies (“reprotech”) like IVF to increase birth rates. Advances in genetic embryo selection, gene editing, in vitro gametogenesis, and artificial wombs could further enhance these policies by improving birth rates, health, and human capital. This article examines current and emerging reprotechnologies, the policy landscape, socioeconomic and geopolitical implications, and future research directions. By shaping national and global gene pools, reprotech policies and practices offer a paradigmatic case of gene–culture coevolution. If these technologies prove safe and effective, nations that embrace them are likely to gain geopolitical and evolutionary advantages over those that do not.
Many people experiencing mental ill health are trapped in cycles of worsening social exclusion. Individual Placement and Support (IPS) is being implemented to support those with mental ill health into employment. However, this intervention does not address the many challenges faced by those who are more vulnerable and is less effective for those with more severe clinical presentations. Although National Health Service (NHS) guidance suggests broader support is needed, there is little clarity over what this should look like. We discuss one model, drawing on years of experience facilitating user-led services at Lambeth Vocational Services, implementing a genuinely person-centred, trust-based approach to facilitate social inclusion.
Amateur and professional athletes often consume protein supplements to accelerate muscle gain; however, it has been suggested that these products not only are associated with risks when consumed excessively. Several recent reports have indicated that certain products are contaminated with heavy metals. Therefore, in this study, we aimed to investigate protein powders in Hungary for heavy metal contamination. A total of 22 commercially available protein powders (including whey, vegan, and beef based) were purchased on the internet for testing. We analysed the samples using laser-induced breakdown spectroscopy (LIBS) and inductively coupled plasma mass spectrometry (ICP-MS) to assess heavy metal contamination. The products were analysed for the presence of 16 elements (Be, Al, Cr, Mn, Co, Ni, Cu, As, Se, Rb, Cd, Sb, Cs, Ba, Hg, and Pb). The LIBS spectral analysis revealed the characteristics of the protein elements (C, C2, H, N, and O) and alkaline metals (Ca, Na, K, and Mg), which were consistent with the previous results. Neither LIBS nor ICP-MS measurements detected significant heavy metal content in the investigated samples above the limit specified in the regulations. Heavy metal contamination of protein supplements can be a serious health threat. Based on the varied results of the previous studies, it is prudent to include testing for heavy metals as part of the routine and mandatory quality control of these products.
Social scientists are paying attention to the role that knowledge plays in economic phenomena. This focus on knowledge has led to exploring two challenges: first, its governance to reap positive externalities and solve social dilemmas, and second, how we can craft institutions to match the intangible nature of ideas with adequate property rules. This article contributes by elaborating on the different knowledge property regimes and the elements contributing to their classification. This paper first taxonomises knowledge governance regimes based on Ostrom’s work on institutional analysis. Second, it examines why governance structures for managing knowledge production vary across industries, according to (1) the characteristics of knowledge, (2) the attributes of the organisations, and (3) the different rules-in-use to enforce property rights. This is the first study at the intersection of institutional analysis and political economy that highlights the knowledge features, incentive structures, and mechanisms undergirding knowledge governance in different property regimes.
The aim of the article is to undertake the first economic analysis exploring the costs of illness (COIs) and factors affecting COIs in people living with mental disorders using individual patient-level data across five countries with different national income levels. This is done by investigating diagnosis-related and sociodemographic factors for country-specific medical and psychosocial service use in these high, lower-middle and low-income countries.
Methods
Using data from the Using Peer Support In Developing Empowering Mental Health Services (UPSIDES) study, a pragmatic randomized controlled trial, costs for medical and psychosocial services have been estimated over 6 months in 615 people with severe mental illness from Germany (n = 171), Uganda (n = 138), Tanzania (n = 110), India (n = 93) and Israel (n = 103). The primary economic analysis included (1) total COI expressed in 2021 international dollars and (2) proportional cost-type expenditures. Generalized linear regression models were also used to estimate the impact of psychiatric diagnosis, social disability, age and gender on the total COI.
Results
Of the 615 participants (mean [SD] age 38.3 [11.2] years; 335 [54.5%] women), the total 6-month COI ranged from $311.48 [±547.47] in Tanzania to $10,493.19 [±13324.10] in Germany. High-income Germany and low-income Uganda both concentrated >70% of COIs on inpatient care. High-income Israel had the most balanced COI, with the lowest mean share (15.40%) on inpatient care, compared with community (35.12%) and primary care (33.01%). Female gender was associated with lower COI (eb = 0.215; p = 0.000) in Tanzania, while in India diagnosis of depression was associated with lower costs than schizophrenia (eb = 0.363; p = 0.017). Health of the Nation Outcome Scale scores (social disability) were not significantly associated with COIs in any country. In Tanzania, the total mean COI increased by 3.6% for every additional year of age. Compared to Germany, mean COIs were significantly lower by 90%, 99% and 86% in Uganda, Tanzania and India, respectively, and by 50% in Israel, although this difference was not significant.
Conclusions
National income is correlated with the total COI in people living with mental disorders but is a poor predictor of the sector-specific distribution of these expenditures.
Reconstructing Quaternary-timescale environmental change in drylands provides insights into styles and rates of change in response to direct insolation forcing and variations in global temperature, ice volume and sea level. Changes to the relatively inhospitable environments presented by drylands are also central to debates about the migration and adaptability of hominin species. This review outlines approaches used for reconstructing past environments, which use dated sequences of environmental proxies – the properties of physical sediments, chemical precipitates and biological materials. In addition, climate model simulations can explore responses to known climatic forcing factors. Advances in both approaches remain situated within conceptual frameworks about dryland responses to: (i) cyclical changes in the Earth’s orbit around the sun, either mediated via the global cryosphere during glacial–interglacial cycles (~100 ka periodicity during the last ~0.9 Ma), or mediated via the response of the global monsoon with ~23 ka periodicity (precession) and (ii) millennial-scale climatic shifts, which are thought to originate outside drylands, within the North Atlantic.
In this review, three examples are outlined to demonstrate areas of emerging consensus and remaining contradictions: (1) speleothem and tufa growth records that span hundreds of thousands of years (ka), (2) conditions at the last glacial maximum (LGM) and (3) proxies recording millennial-scale events. Precessional-scale forcing of the monsoon is not always observed, with apparent mediating roles from glacial boundary conditions in parts of the northern hemisphere (NH) and from interglacial boundary conditions in parts of the southern hemisphere (SH). The LGM in drylands was initially conceptualised as experiencing pluvial (wet) conditions, which shifted to a glacial aridity paradigm, and is again shifting to a pattern of global heterogeneity, in which some drylands were wetter-than-present and others drier. However, there remain contradictions between environmental proxies and model simulations, and spatial heterogeneity is observed within many drylands. Dryland proxies that record millennial-scale events demonstrate clearly the importance of climatic teleconnections across the globe in influencing dryland hydroclimate. The records of Quaternary dryland change across a range of timescales get used alongside simulations of ecosystem response through time, hominin habitat and even hominin physiology to better understand likely hominin dispersals through dryland regions.
We compare the Emory 10-item, 4-choice Rey Complex Figure (CF) Recognition task with the Meyers and Lange (M&L) 24-item yes/no CF Recognition task in a large cohort of healthy research participants and in patients with heterogeneous movement disorder diagnoses. While both tasks assess CF recognition, they differ in key aspects including the saliency of target and distractor responses, self-selection versus forced-choice formats, and the length of the item sets.
Participants and Methods:
There were 1056 participants from the Emory Healthy Brain Study (EHBS; average MoCA = 26.8, SD = 2.4) and 223 movement disorder patients undergoing neuropsychological evaluation (average MoCA = 24.3, SD = 4.0).
Results:
Both recognition tasks differentiated between healthy and clinical groups; however, the Emory task demonstrated a larger effect size (Cohen’s d = 1.02) compared to the M&L task (Cohen’s d = 0.79). d-prime scoring of M&L recognition showed comparable group discrimination (Cohen’s d = 0.81). Unidimensional two-parameter logistic item response theory analysis revealed that many M&L items had low discrimination values and extreme difficulty parameters, which contributed to the task’s reduced sensitivity, particularly at lower cognitive proficiency levels relevant to clinical diagnosis. Dimensionality analyses indicated the influence of response sets as a potential contributor to poor item performance.
Conclusions:
Emory CF Recognition task demonstrates superior psychometric properties and greater sensitivity to cognitive impairment compared to the M&L task. Its ability to more precisely measure lower levels of cognitive functioning, along with its brevity, suggests it may be more effective for diagnostic use, especially in clinical populations with cognitive decline.
Culture is increasingly articulated by financial actors and financial firms as a solution to the dislocations of contemporary capitalism. It therefore matters, not just how actors behave, but how they articulate culture and what importance they accord it. Drawing on pragmatist sociology, the present paper takes this injunction seriously and reports the findings of a field study involving 29 interviews with senior members of financial firms whose understanding of culture and its importance were interrogated directly. The discourse concerning purposeful culture articulated in these interviews simultaneously recognises current arrangements between finance and society as fractured while positing organisational culture initiatives as the most realistic means of repairing said fracture. The paper draws on these findings to argue that, despite masquerading as a call for change, purposeful culture discourse has the effect of protecting against calls to rethink or radically transform the roles and effects of finance in society. The paper thus contributes to sociological perspectives on finance by illustrating how existing cultural discourse in financial markets serves as a kind of conservative critique where shortcomings are conceded in a way which insulates finance from wider structural change.
This article tries to explain the flourishing of geopolitical alternatives to the nation-state form and foreign policies organized around giant militarized power blocs during the two decades after World War II. The first section presents these new approaches to organizing the world. The first set of alternatives consisted of ideas and practices of the federation and the amalgamation of states into larger political units. These included Senghor’s vision of a postcolonial federation in which France and its former colonies would be equals; Nkrumah’s vision of a United States of Africa; and various short-lived amalgamations of states, including the Mali Federation and the United Arab Republic. These new geopolitical alternatives also included nonalignment, which originated with Jawaharlal Nehru of India and culminated with Josip Broz Tito of Yugoslavia but also encompassed Ireland between 1957 and 1961 and France in the early Fifth Republic. One of the distinctive features of this conjuncture is that these experiments were not limited to the global peripheries, colonies, and recently decolonized states, but also characterized certain nonhegemonic European core countries. The second section examines a set of four factors in this period that created an opportunity structure or space of possibilities for geopolitical experimentation: (1) late colonialism; (2) the Cold War; (3) the character of decolonization; and (4) the United Nations. The coexistence of these factors opened spaces of maneuver and autonomy for a flourishing of geopolitical imaginaries. The final section discusses possible reasons for the end of this period of experimentation.
The global food system puts enormous pressure on the environment. Managing these pressures requires understanding not only where they occur (i.e., where food is produced), but also who drives them (i.e., where food is consumed). However, the size and complexity of global supply chains make it difficult to trace food production to consumption. Here, we provide the most comprehensive dataset of bilateral trade flows of environmental pressures stemming from food production from producing to consuming nations. The dataset provides environmental pressures for greenhouse gas emissions, water use, nitrogen and phosphorus pollution, and the area of land/water occupancy of food production for crops and animals from land, freshwater, and ocean systems. To produce these data, we improved upon reported food trade and production data to identify producing and consuming nations for each food item, allowing us to match food flows with appropriate environmental pressure data. These data provide a resource for research on sustainable global food consumption and the drivers of environmental impact.
Viscoplastic fluids exhibit yield stress, beyond which they flow viscously, while at lower stress levels they behave as solids. Despite their fundamental biological and medical importance, the hydrodynamics of swimming in viscoplastic environments is still evolving. In this study, we investigate the swimming of an ellipsoidal squirmer and the associated tracer diffusion in a Bingham viscoplastic fluid. The results illustrate that neutral squirmers in viscoplastic fluids experience a reduction in swimming speed and an increase in power dissipation as the Bingham number increases, with swimming efficiency peaking at moderate Bingham numbers. As the aspect ratio of a squirmer increases, ellipsoidal squirmers exhibit significantly higher swimming speeds in viscoplastic fluids. The polar and swirling modes can either enhance or reduce swimming speed, depending on the specific scenarios. These outcomes are closely related to the confinement effects induced by the yield surface surrounding the swimmer, highlighting how both swimmer shape and swimming mode can significantly alter the yield surface and, in turn, modify the swimming hydrodynamics. In addition, this study investigates the influence of viscoplasticity on swimmer-induced diffusion in a dilute suspension. The plasticity enforces the velocity far from the swimmer to be zero, thus breaking the assumptions used in Newtonian fluids. The diffusivity reaches its maximum at intermediate aspect ratios and Bingham numbers, and increases with the magnitude of the squirmer’s dipolarity. These findings are important to understand microscale swimming in viscoplastic environments and the suspension properties.
Historians of colonial and postcolonial attempts to deal with undernutrition in Africa have generally argued that, after the Second World War, scientists and doctors “medicalized” hunger by emphasizing specific deficiencies that could be medically “cured” or alleviated through dietary supplements, thereby covering up the economic, social, and political causes of (post)colonial hunger. This article argues that this explanation obscures the persistence of a more holistic approach immediately after the Second World War, which rejected this narrow vision of hunger and, on the contrary, framed it as a very broad problem requiring interdisciplinary research and ambitious economic and social solutions. It focuses in particular on the work of British nutrition specialist B. S. Platt and his “experiment” in The Gambia that was meant to devise a replicable recipe to cure colonial malnutrition through mechanization and agricultural development. Like many other such colonial projects, the project ended in dismal failure, but it illustrates how malnutrition was understood at the end of the war as a broad economic and social problem. It also shows how this more holistic approach was tightly associated with the postwar project of colonial “development” and was predicated on an ambition to thoroughly re-engineer colonial landscapes and subjects.
The U.S. Supreme Court is often regarded as an impartial arbiter of justice, yet various prejudices may influence its decisions. This article examines Supreme Court justices’ biases, focusing on how they invoke racialized stereotypes of criminality. We argue that justices are more likely to vote in favor of white, nonviolent litigants, reinforcing stereotypes that depict nonwhite defendants as inherently more criminal and violent. Drawing on the U.S. Supreme Court Database’s criminal procedure cases from 2005–2017, combined with an original dataset of litigants’ racial identities, we estimate a series of multilevel logistic regressions. Our findings show that litigant race, crime type, and justice ideology jointly shape judicial votes. We further investigate how bias appears in justices’ written opinions, revealing language that perpetuates racialized conceptions of criminality. Overall, our results underscore the Court’s role in constructing what it means to be both “criminal” and “nonwhite,” suggesting that the Court is not a neutral interpreter of law, but an institution shaped by broader social and political biases.
While gender-based violence (GBV) is increasingly recognised as a significant social and political issue, its impact on women educators remains underexamined. In the context of growing concerns about violence against educators and the prevalence of GBV in educational institutions, this study investigates gendered patterns of violence against school leaders in Australian schools. Drawing on 18,172 observations from reports by principals and deputy principals, this analysis explores incidents of bullying, threats of violence, and physical violence to identify disparities in the experiences of men and women school leaders. The analysis determined that women school leaders were more likely to experience threats of violence and bullying at work than their male counterparts. Logistic regression analyses revealed that gender, school sector, and role significantly influence the likelihood of experiencing various forms of workplace violence, with women in secondary schools and those in government or Catholic sectors being particularly vulnerable.