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Catch-neuter-vaccinate-release (CNVR) programmes for free-roaming dogs (FRD) are humane and effective in controlling dog populations in developing countries. However, each component, from capture to release, can impact an individual animal’s welfare. This study aimed to develop a standardised welfare assessment scoring system for evaluating the welfare of dogs undergoing routine CNVR procedures at a veterinary training facility in Goa, India and to assess the impact of a targeted staff training intervention by comparing welfare assessment scores before and after its implementation. A score-based protocol was designed, incorporating 22 animal-, resource-, and management-based parameters covering six key steps of the CNVR procedure: catching/transport; cage/holding area; pre-operative period; surgery; post-operative period; and release. Eighty-two dogs were assessed initially. Areas for improvement were identified and informed the design of a targeted staff training intervention involving theory-based lectures and interactive sessions. Knowledge was assessed before and after receiving the intervention, with total scores on the assessment improving. The welfare assessment was repeated on another 81 dogs. Total welfare scores for individual dogs improved significantly after the staff intervention compared with before. This study demonstrates that a welfare assessment tool can be used to assess the welfare of individual dogs in a busy CNVR programme; furthermore, it can inform the compilation and delivery of a targeted staff training intervention and demonstrate improvements in dog welfare after such an intervention.
This Article brings together two important concepts in international law scholarship that have thus far been studied in isolation from each other: reputation and interpretation. Interesting insights lie hidden in their overlap. While interpretation is still commonly perceived as a sterile exercise in “legal logic,” the Article suggests that it is often better studied as a social practice, within which the relationships between the interpreters that are arguing with each other frequently matter as much as the arguments themselves. The Article therefore suggests a new way of looking at interpretation in international law: Interpretation as a practice of reputation management, where collective actors like states present themselves to others in the interpretations they adopt, and are evaluated by various audiences on the basis of these interpretations. The main argument can be summarized like this: If international law is relatively indeterminate, interpretation is a situated choice. By making that choice, an interpreter reveals something fundamental about itself to its audiences. Interpreters therefore carefully manage their interpretive expressions out of a desire to be well-regarded by these audiences. This phenomenon of reputation management has important implications for the practice of interpretation in international law.
The conclusion summarises the findings of the book, using two case studies of composite local priests in 900 and 1050 to bring out some of the key changes that had taken place over this period in how the Church functioned at the local level. It considers the causes that lay behind these changes and explores the historiographical implications of these findings.
For traditional textiles, geographical indication (GI) protection offers improved brand visibility while insulating a hard-earned reputation against misuse. This form of IP has additional synergies with the shift towards more sustainable production and consumption in the global fashion industry. These textiles have conventionally used natural fibres, organic dyes and artisanal methods. They are also meant to be reused, unlike fast fashion. This chapter investigates this ‘GI optimism’, asking whether there are legal and institutional mechanisms to systematically reinforce sustainability commitments. It unpacks a recent regulatory reform in the EU, whereby the GI product specification can incorporate voluntary ‘sustainability undertakings’ by producer groups. The chapter concludes by observing that synergies between different aspects of sustainability should not be taken for granted, if GI law is to truly deliver on ‘threads that last’.
This article considers a curious document – Baker’s Australian County Atlas – which contains carefully illustrated maps of each of the 19 counties in the colony of New South Wales in the mid-1840s. The analysis seeks to bridge the gap between high-level geographical studies of the British invasion of New South Wales and historical analysis of settler colonial property formation. We argue that the Atlas reveals the mechanics of territorial accumulation and Aboriginal dispossession in nineteenth-century New South Wales in their historical and material specificity, locating instances of ‘improvement’ – clearing, fencing and the construction of temporary and permanent buildings – at the centre of settler colonial land administration and sovereignty. The article demonstrates that the legal obligation to improve ultimately regulated colonial urbanization, enacting a process in which buildings and other structures functioned less as ends in themselves than as discrete operations within a more pervasive and abiding process of dispossession.
Clozapine is licensed for treatment-resistant schizophrenia (TRS). Because of the risk of clozapine-induced agranulocytosis, its use requires regular haematological monitoring. Substantive evidence supports revisions of absolute neutrophil counts (ANCs) for clozapine discontinuation and ceasing of indefinite haematological monitoring.
Aims
To examine the cost-effectiveness and budget impact of different haematological monitoring schemes compared with the current UK monitoring practice for patients using clozapine.
Method
We performed a cost-effectiveness and budget impact analysis from the healthcare system perspective over a 3-year period, comparing the current UK clozapine monitoring practice with extended haematological monitoring and a revision of ANC criteria. Costs and quality-adjusted life years (QALYs) were estimated using a semi-Markov model that followed a simulated cohort of 100 000 adults with TRS. Sensitivity analyses were conducted.
Results
Extended haematological monitoring would lead to lower mean total costs per patient (6388.34 v. 5569.77 GBP) and not compromise quality of life (in QALYs 795.83 v. 795.79 days). A revision of ANC criteria for clozapine discontinuation would not substantially lower costs (6388.34 v. 6390 GBP), but lead to a slight increase in QALYs (795.83 v. 797.08 days), through patients benefitting from longer clozapine treatment. A combination of extended haematological monitoring and revision of ANC criteria would be the dominant strategy, which means that costs are lower (6388.34 v. 5548.50 GBP) and QALYs slightly increase (795.83 v. 797.03 days) compared with the current UK monitoring practice.
Conclusions
A revision of current UK clozapine monitoring practice would be beneficial from both a clinical and an economic perspective. Adjusting ANC criteria for clozapine cessation avoids unnecessary early discontinuation of clozapine treatment and has a positive impact on quality of life. An extension of monitoring intervals reduces costs borne by the healthcare system. Safety is not compromised by these changes.
This article draws upon Walter Benjamin’s concept of “aura” to examine how the reproductions of religious images in domestic settings are (re)infused with spiritual power. Based on an ethnographic study of Coptic Christians in Upper Egypt, I argue that the “aura” of these paintings emerges through semiotic management that tightens a preexisting link, stemming from the minority status of Copts, between house and church. To this end, I discuss how patrons and artists reshape, modify, and enhance both the subject-matter of these reproductions as well as certain formal properties like surfaces and frames. This semiotic labor clarifies a privileged zone of interaction I refer to as “the near-sacred,” which can be compared to Benjamin’s understanding of the conceptual proximity of art to ritual. I conclude by proposing the near-sacred as a site for studying how circulating religious signs (re)acquire a spiritual valence at the periphery of institutional religious practice.
We analyze how corporate direct investments in fintech startups affect startup performance and that of investing firms. Corporate investment in fintech startups is associated with a greater likelihood of successful exit, more and higher-quality innovation, and a greater inflow of high-quality inventors. A stacked difference-in-differences analysis shows that direct investments enhance the operating performance and equity-market valuation of corporate investors in the financial services sector, but not those in the nonfinancial sector. We establish two channels that drive fintech startups’ performance improvements: strategic alliance formation between investors and startups, and enhanced startup monitoring by corporate investors.
Research has robustly demonstrated that children exposed to early ecological adversity are at risk for developing antisocial, externalizing behavior problems (rule breaking, aggression, disregard for others). Yet, studies have also demonstrated multifinality in developmental pathways unfolding in adversity’s aftermath, with many children showing remarkable resilience. Understanding sources of such resilience is critical, especially across different populations (Luthar et al., 2006, 2015). In Family Study (FS, 102 low-risk mothers, fathers, and infants) and Play Study (PS, 186 high-risk mother-toddler dyads), we test a model of parent–child attachment security, observed at 15 months in FS and 2.5 years in PS, as a moderator of effects of early family ecological adversity, assessed as a cumulative score of sociodemographic risks (graded for severity) at 7 months in FS and 2.5 years in PS, on children’s antisocial, externalizing problems, observed and parent-reported at 5.5 years in FS and 7 years in PS. We supported moderation for mother–child relationships in both studies: Higher early family adversity was associated with more antisocial outcomes five years later, but only for children with less secure attachments. We highlight the key role of early security as a protective factor and a source of resilience for children in families experiencing adversity.
Numerous studies have investigated the impact of climate change on tree growth and carbon sequestration, exploring the effect of climatic factors on the onset and cessation of wood formation. Some studies used microcores for histological observations of xylem, while many others used dendrometer recordings to infer stem growth. However, the reliability of dendrometers in providing accurate estimates of growth phenology has yet to be fully assessed. We compared the phenology estimated using dendrometer- and microcore-based approaches for six tree species growing in contrasted site conditions and exhibiting contrasted tree-ring structures (non-porous, diffuse-porous and ring-porous) and bark types (smooth, scaled, fissured). Our results show that dendrometer estimate accuracy is poor and varied according to several factors, including species life traits, climate and site conditions. These results highlight the limitations of dendrometers in evaluating wood phenology in trees, and advocate for the concurrent monitoring of xylogenesis.
This chapter analyses the evolving role of states in safeguarding freedom of expression within the digital environment, particularly on social media platforms. It highlights how states have both negative obligations (to avoid undue interference) and positive obligations (to actively protect and ensure the right to freedom of expression). The European Court of Human Rights and other international bodies emphasise that states must create a favourable environment for public debate, protect speakers from harm, and ensure media pluralism. These obligations extend to relations between private parties, including users and internet intermediaries. The chapter emphasises that freedom of expression in the digital age requires states to actively safeguard rights while balancing regulation and accountability. It warns against reliance on private platforms for enforcing speech limitations and underscores the importance of transparent, rights-based governance.
This chapter describes how the Caribbean Court of Justice is embedded within colonial legacies that have affected regional political norms and legal culture. It shows the CCJ’s decisions are characterized by moderate deference, infrequently ruling in favor of states and typically eschewing restrictive interpretation. More deference, however, is observed through the Court’s remedial orders. The chapter links the CCJ’s tendency to not defer to its intermediate political constraints. Specifically, the CCJ’s strategic space is shaped by high formal independence that is partially offset by homogeneous state preferences. These factors combine to affect the Court’s legitimacy and signal when state resistance might be feasible and credible. In particular, the CCJ defers more when states are clearly aligned. The Court’s nondeference is facilitated by the Court’s practices of persuasive argumentation and public legitimation. The chapter also suggests the CCJ’s support network lacks the robustness necessary to account for its moderate deference.
This paper argues that debates concerning gender terms and context sensitivity should take into account retraction, i.e., the ability to take back a previously true assertion of one’s gender identity. We begin by rejecting the intuition that gender terms should vary in truth value based on the “medical” and “bathroom” scenarios, where a trans woman (or man) should be classed as a woman (or man) in the latter, but not the former because she (or he) lacks certain organs (e.g. cervix or testicles). Assigning authority to self-identification, we hold that if someone identifies as a woman in bathroom scenarios she should also be classed as a woman in medical scenarios. Instead, we draw support for context sensitivity of gender terms from retraction data. We take gender retraction to be supported by the testimonies of trans people. Specifically, we explore the less discussed Later in Life narrative where individuals come to realise their true gender identities later in life. After demonstrating the shortfalls of existing contextualist accounts of retraction, we present a novel version of semantic relativism - Gender Relativism - that is faithful to gender testimonies. Our view accounts for retraction, takes into consideration self-identification and explains why transphobic denials of an individual’s gender testimony are false.
This chapter conceptualizes deference as an international court’s acceptance of the state’s exercise of authority. It presents a method for measuring deference that combines case outcomes, interpretation, and remedial orders. The chapter introduces a novel theoretical account of deference. This explanation centers on a court’s strategic space, or the range of possible decisions that will satisfy a court’s legal and political imperatives, and argues that two political factors determine this strategic space: formal independence and political fragmentation. The former concerns the formal rules that safeguard independence while the latter refers to the heterogeneity of states’ preferences. These two constraints affect deference by way of their impact on a court’s legitimacy and the feasibility and credibility of state resistance. The theoretical account also considers the role of persuasive argumentation, public legitimation, and past resistance. This explanation is distinguished from accounts that emphasize judicial support networks and political norms and legal culture.