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Resolvent-based modelling and estimation is critically dependent on the nonlinear forcing input and hence understanding its role in the flow response is of great significance. This study quantifies the nonlinear forcing input in the resolvent formulation and investigates its characteristics for compressible turbulent boundary layers at Mach number 5.86 and friction Reynolds number 420 subject to adiabatic- and cold-wall conditions. Results show that, with the addition of the eddy viscosity to the resolvent operator, the cross-spectral density (CSD) of the forcing tends to exhibit a spatially uncorrelated distribution, which suggests that the spatial cross-coherence may be neglected and makes the modelling of the forcing input potentially easier. Aiming to quantify the different importance of each forcing component in generating turbulent fluctuations, contributions of the eddy-viscosity-corrected forcing to the flow responses are investigated through reduced-order analysis and matrix decomposition. The streamwise motions are almost insensitive to the temperature-related forcing, and can be oppositely influenced by the wall-normal and spanwise forcing components. By retaining only the diagonal components in the CSD of the forcing input, the assumption of forcing decorrelation in space and among components is also examined in the input–output framework. It is found that this simplified input is able to capture the dominant turbulence features and the local forcing is observed to cause inner-layer responses. That is, present results suggest adequate modelling of the CSD of the forcing can be achieved retaining only its diagonal components. On the basis of the current findings, the forcing input in the resolvent-based framework is thus modelled, with the wall-normal dependence and amplitude ratio between forcing components designed for compressible turbulent boundary layers. Through an algebraic Lyapunov equation, improved estimations of the statistical spectral densities of velocity and temperature fluctuations are finally obtained, in contrast to the results by simply assuming the forcing CSD to be an identity matrix.
This study aimed to examine the relationship between FGF19 and depressive symptoms, measured by BDI scores and investigate the moderating role of smoking.
Methods:
This study involved 156 Chinese adult males (78 smokers and 78 non-smokers) from September 2014 to January 2016. The severity of depressive symptoms was evaluated using the BDI scores. Spearman rank correlation analyses were used to investigate the relationship between CSF FGF19 levels and BDI scores. Additionally, moderation and simple slope analyses were applied to assess the moderating effect of smoking on the relationship between the two.
Results:
FGF19 levels were significantly associated with BDI scores across all participants (r = 0.26, p < 0.001). Smokers had higher CSF FGF19 levels and BDI scores compared to non-smokers (445.9 ± 272.7 pg/ml vs 229.6 ± 162.7 pg/ml, p < 0.001; 2.7 ± 3.0 vs 1.3 ± 2.4, p < 0.001). CSF FGF19 levels were positively associated with BDI scores in non-smokers (r = 0.27, p = 0.015), but no similar association was found among smokers (r = -0.11, p = 0.32). Linear regression revealed a positive correlation between FGF19 and BDI scores (β = 0.173, t = 2.161, 95% CI: 0.015- 0.331, p < 0.05), which was negatively impacted by smoking (β = -0.873, t = -4.644, 95% CI: -1.244 to -0.501, p < 0.001).
Conclusion:
These results highlight the potential role of FGF19 in individuals at risk for presence of or further development of depressive symptoms and underscore the importance of considering smoking status when examining this association.
Emission line galaxies (ELGs) are crucial for cosmological studies, particularly in understanding the large-scale structure of the Universe and the role of dark energy. ELGs form an essential component of the target catalogue for the Dark Energy Spectroscopic Instrument (DESI), a major astronomical survey. However, the accurate selection of ELGs for such surveys is challenging due to the inherent uncertainties in determining their redshifts with photometric data. In order to improve the accuracy of photometric redshift estimation for ELGs, we propose a novel approach CNN–MLP that combines convolutional neural networks (CNNs) with multilayer perceptrons (MLPs). This approach integrates both images and photometric data derived from the DESI Legacy Imaging Surveys Data Release 10. By leveraging the complementary strengths of CNNs (for image data processing) and MLPs (for photometric feature integration), the CNN–MLP model achieves a $\sigma_{\mathrm{NMAD}}$ (normalised median absolute deviation) of 0.0140 and an outlier fraction of 2.57%. Compared to other models, CNN–MLP demonstrates a significant improvement in the accuracy of ELG photometric redshift estimation, which directly benefits the target selection process for DESI. In addition, we explore the photometric redshifts of different galaxy types (Starforming, Starburst, AGN, and Broadline). Furthermore, this approach will contribute to more reliable photometric redshift estimation in ongoing and future large-scale sky surveys (e.g. LSST, CSST, and Euclid), enhancing the overall efficiency of cosmological research and galaxy surveys.
The fall armyworm, Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae), is a highly destructive polyvorous pest with a wide host range and the ability to feed continuously with seasonal changes. This destructive pest significantly damages crops and can also utilize non-agricultural plants, such as weeds, as alternative hosts. However, the adaptation mechanisms of S. frugiperda when switching between crop and non-crop hosts remain poorly understood, posing challenges for effective monitoring and integrated pest management strategies. Therefore, this study aims to elucidate the adaptability of S. frugiperda to different host plants. Results showed that corn (Zea mays L.) was more suitable for the growth and development of S. frugiperda than wheat (Triticum aestivum L.) and goosegrass (Eleusine indica). Transcriptome analysis identified 699 genes differentially expressed when fed on corn, wheat, and goosegrass. The analysis indicated that the detoxification metabolic pathway may be related to host adaptability. We identified only one SfGSTs2 gene within the GST family and investigated its functional role across different developmental stages and tissues by analysing its spatial and temporal expression patterns. The SfGSTs2 gene expression in the midgut of larvae significantly decreased following RNA interference. Further, the dsRNA-fed larvae exhibited a decreased detoxification ability, higher mortality, and reduced larval weight. The findings highlight the crucial role of SfGSTs2 in host plant adaptation. Evaluating the feeding preferences of S. frugiperda is significant for controlling important agricultural pests.
A key step toward understanding psychiatric disorders that disproportionately impact female mental health is delineating the emergence of sex-specific patterns of brain organisation at the critical transition from childhood to adolescence. Prior work suggests that individual differences in the spatial organisation of functional brain networks across the cortex are associated with psychopathology and differ systematically by sex.
Aims
We aimed to evaluate the impact of sex on the spatial organisation of person-specific functional brain networks.
Method
We leveraged person-specific atlases of functional brain networks, defined using non-negative matrix factorisation, in a sample of n = 6437 youths from the Adolescent Brain Cognitive Development Study. Across independent discovery and replication samples, we used generalised additive models to uncover associations between sex and the spatial layout (topography) of personalised functional networks (PFNs). We also trained support vector machines to classify participants’ sex from multivariate patterns of PFN topography.
Results
Sex differences in PFN topography were greatest in association networks including the frontoparietal, ventral attention and default mode networks. Machine learning models trained on participants’ PFNs were able to classify participant sex with high accuracy.
Conclusions
Sex differences in PFN topography are robust, and replicate across large-scale samples of youth. These results suggest a potential contributor to the female-biased risk in depressive and anxiety disorders that emerge at the transition from childhood to adolescence.
We investigate the dynamics of close-contact melting (CCM) on ‘gas-trapped’ hydrophobic surfaces, with specific focus on the effects of geometrical confinement and the liquid–air meniscus below the liquid film. By employing dual-series and perturbation methods under the assumption of small meniscus deflections, we obtain numerical solutions for the effective slip lengths associated with velocity $\lambda$ and temperature $\lambda _t$ fields, across various values of aspect ratio $\Lambda$ (defined as the ratio of the film thickness $h$ to the structure’s periodic length $l$) and gas–liquid fraction $\phi$. Asymptotic solutions of $\lambda$ and $\lambda _t$ for $\Lambda \ll 1$ and $\Lambda \gg 1$ are derived and summarised for different surface structures, interface shapes and $\Lambda$, which reveal a different trend of $\lambda$ for $\Lambda \ll 1$ and depending on the presence of a meniscus. In the context of constant-pressure CCM, our results indicate that longitudinal grooves can enhance heat transfer under the effects of confinement and a meniscus when $\Lambda \lesssim 0.1$ and $\phi \lt 1 - 0.5^{2/3} \approx 0.37$. For gravity-driven CCM, the parameters of $l$ and $\phi$ determine whether the melting rate is enhanced, reduced or nearly unaffected. We construct a phase diagram based on the parameter matrix $(\log _{10} l, \phi )$ to delineate these three regimes. Lastly, we derive two asymptotic solutions for predicting the variation in time of the unmelted solid height.
where $c_+$ and $c_-$ are two positive constants. It is shown that the solution of the step-like initial problem can be characterised via the solution of a matrix Riemann–Hilbert (RH) problem in the new scale $(y,t)$. A double coordinate $(\xi, c)$ with $c=c_+/c_-$ is adopted to divide the half-plane $\{ (\xi, c)\,:\, \xi \in \mathbb{R}, \ c\gt 0, \ \xi =y/t\}$ into four asymptotic regions. Further applying the Deift–Zhou steepest descent method, we derive the long-time asymptotic expansions of the solution $u(y,t)$ in different space-time regions with appropriate g-functions. The corresponding leading asymptotic approximations are given with the slow/fast decay step-like background wave in genus-0 regions and elliptic waves in genus-2 regions. The second term of the asymptotics is characterised by the Airy function or parabolic cylinder model. Their residual error order is $\mathcal{O}(t^{-2})$ or $\mathcal{O}(t^{-1})$, respectively.
The proposed Thermal Sidewall Ice Corer (TSIC) is designed to accurately sample horizontal ice layers of scientific interest, such as tephra layers, basal ice and shear zones, and retrieve ice cores back to the surface. The system features a bending core barrel with a thermal coring head, which bends as it extends from the drill body, enabling it to penetrate horizontal interlayers while maintaining a horizontal position until the ice core is extracted. The bending core barrel is driven by screw pairs, powered by a motor, to apply drilling load and pulling force. As the barrel bends, the ice cores are broken inside and transported to the surface along with the drill via a winch. A camera system has been incorporated into the TSIC to precisely locate the target layer. The corer is suitable for ice boreholes with diameters ranging from 135 to 170 mm, capable of retrieving ice cores with a diameter of 20–30 mm, and achieving a maximum penetration rate of 2 m h−1. The maximum length of ice samples that can be retrieved in a single drilling run is 500 mm. The coring performance for horizontal sampling has been validated through the development and testing of a prototype in the laboratory.
Wave impact on solid structures is a well-studied phenomenon, but almost exclusively for the case that the impacting liquid (e.g. water) is surrounded by a non-condensable gas (such as air). In this study we turn to wave impact in a boiling liquid, a liquid that is in thermal equilibrium with its own vapour, which is of key relevance to the transport of cryogenic liquids, such as liquified natural gas and liquid hydrogen in the near future. More specifically, we use the Atmosphere facility at MARIN, NL, to prepare water/water vapour systems at different temperatures along the vapour curve. Here, we perform wave impact experiments by generating a soliton in a flume contained within the autoclave of the facility. A bathymetry profile interacts with the soliton, leading to a breaking wave that impacts onto a vertical wall, where we measure the pressures occurring during impact by means of $100$ embedded pressure sensors. In boiling liquids, we report wave impact pressures that are up to two orders of magnitude larger than those measured in comparable water–air experiments. We trace these pressures back to the collapse of the entrapped vapour pocket, which we semi-quantitatively describe using a simplified hemicylindrical vapour bubble model, which is in good agreement with the experimental findings. Finally, this allows us to predict the relevance of our findings for the transport of cryogenic liquids in huge overseas carriers where wave impact due to sloshing is the dominant cause of hydrodynamic load of containment systems in cargo tanks.
Raman fiber lasers, known for their capacity to provide both high-power and precise wavelength emissions, are gaining attraction across a spectrum of applications, including fiber optic communications, sensing, spectroscopy and imaging. However, the scalability of Raman laser power is impeded by the constraints of pump brightness and the deleterious effects of second-order Raman scattering. In this research, we have undertaken a comprehensive experimental and simulation-based investigation into the impact of pump brightness on the output characteristics within an amplifier framework. Our innovative approach integrates high-brightness pumping with multi-mode graded-index fibers. Notably, we have pioneered the introduction of multi-wavelength seed light to facilitate four-wave mixing, thereby effectively mitigating higher-order Raman scattering. This novel strategy has culminated in the achievement of a 4 kW Raman laser output in an all-fiber configuration, representing the highest output power reported so far.
We study the dynamics of a thin liquid sheet that flows upwards along the sides of a vertically aligned, impacting plate. Upon impact of the vertical solid plate onto a liquid pool, the liquid film is ejected and subsequently continues to flow over the solid surface while the plate enters the water. With increasing impact velocity, the liquid film is observed to rise up faster and higher. We focus on the time evolution of the liquid film height and the thickness of its upper rim and discuss their dynamics in detail. Similar to findings in previous literature on sheet fragmentation during drop impact, we find the rim thickness to be governed by the local instantaneous capillary number based on gravity and the deceleration of the liquid sheet, showing that the retraction of the rim is primarily due to capillarity. In contrast, for the liquid film height, we demonstrate that the viscous dissipation in the thin boundary layer is the dominant factor for the vertical deceleration of the liquid sheet, by modelling the time evolution of the film height and showing that the influences of capillarity, gravity and deceleration due to the air phase are all negligible compared with the viscous term. Finally, we introduce characteristic viscous time and length scales based on the initial rim thickness and show that the maximum height of the film and the corresponding time can be determined from these viscous scales.
Observers were randomized to time and location across two different Neonatal Intensive Care Units (NICUs) to count hand hygiene opportunities (HHOs). Mean hourly HHO was lower at night and during use of precautions, and higher in shared rooms. HHO benchmarks can support implementation of group electronic monitoring systems in NICUs.
Right anterolateral thoracotomy or left anterolateral thoracotomy applied to partial anomalous pulmonary venous connection correction have been reported to obtain cosmetic and less invasive outcomes as alternative approaches to median sternotomy. However, the application of different approaches is still confusing. We compared the perioperative and mid-term outcomes to seek indications of different approaches and guide surgical treatment of partial anomalous pulmonary venous connection.
Methods:
From July 2019 to August 2023, 44 patients who underwent surgical correction of partial anomalous pulmonary venous connection were recruited. Of these, 13 (29.6%) patients who underwent median sternotomy were separated into M group, 28 (63.6%) patients who underwent right anterolateral thoracotomy were separated into R group, and three (6.8%) patients who underwent left anterolateral thoracotomy were separated into L group. Clinical data were reviewed and compared between each group.
Results:
In M group, direct anastomosis accounted for the most (7, 53.8%), in R group, intra-atrial rerouting accounted for the most (22, 78.6%), and in L group, direct anastomosis accounted for the most (3, 100%). R group had shorter cardiopulmonary bypass time (70.0 ± 32.4 vs113.1 ± 83.3, p = 0.029), shorter ICU stay (1.0 ± 0.2 vs 1.9 ± 1.7, p = 0.01), shorter postoperative stay (6.0 ± 1.2 vs 8.3 ± 5.0, p = 0.021), and fewer chest tube drainage (8.4 ± 4.3 vs 13.9 ± 10.2, p = 0.026) compared with M group. Three left-sided partial anomalous pulmonary venous connection in L group adopted off-pump approach.
Conclusions:
Median sternotomy S.V.C. can be applicable to all anatomic types of partial anomalous pulmonary venous connection especially for complex types. Considering the minimally invasive advantages, we prefer applying right anterolateral thoracotomy for pulmonary vein connected to right atrium or proximal end of off-pump. Applying left anterolateral thoracotomy for left-sided partial anomalous pulmonary venous connection without atrial septal defect by off-pump.
Rhopalosiphum padi is an important grain pest, causing severe losses during crop production. As a systemic insecticide, flonicamid can control piercing-sucking pests efficiently. In our study, the lethal effects of flonicamid on the biological traits of R. padi were investigated via a life table approach. Flonicamid is highly efficiently toxic to R. padi, with an LC50 of 9.068 mg L−1. The adult longevity and fecundity of the R. padi F0 generation were markedly reduced under the LC25 and LC50 concentrations of flonicamid exposure. In addition, negative transgenerational effects on R. padi were observed under exposure to lethal concentrations of flonicamid, with noticeable decreases in the reproductive period, adult longevity, total longevity, and total fecundity of the F1 generation under the LC25 concentration of flonicamid. Furthermore, the third nymph stage (N3), preadult stage, duration of the adult pre-reproductive period, duration of the total pre-reproductive period, reproductive period, adult longevity, total longevity, and total fecundity of the F1 generation were significantly lower under treatment with the LC50 concentration of flonicamid. The life table parameters were subsequently analysed, revealing that the intrinsic rate of increase (rm) and the net reproductive rate (R0) were significantly lower but that the finite rate of increase (λ) and the mean generation time (T) were not significantly different under the LC25 and LC50 concentrations of flonicamid. These data are beneficial for grain aphid control and are critical for exploring the role of flonicamid in the integrated management of this key pest.
A compact microstrip eight-channel diplexer based on quad-mode stepped impedance resonator (QMSIR) is proposed in this paper. The proposed diplexer is composed by two second-order quad-band bandpass filters (BPFs) and common-port distributed coupling matching circuit. Each quad-band BPF is formed by two coupled-QMSIRs controlling the passband characteristics. By introducing multiple coupling paths between input and output ports, the isolation between the eight channels is performed. For demonstration, an eight-channel diplexer based on QMSIR is designed and fabricated with microstrip technology. The use of the QMSIR can lead to significant size reduction for the multiplexer, this is because the required resonator number is reduced. As a result, the diplexer occupies a compact size of 0.083λ2, which is smaller than most of the eight-channel diplexers that have been proposed. And the 3 dB fractional bandwidth is 97% (2.5–7.2 GHz). Measurement results correlate well with the simulated predictions, showing that a good isolation of better than 20 dB and upper stopband of better than 10 dB.
The bevelled nozzle is a promising noise control approach and has been tested to suppress the noise levels in supersonic circular jets, but not in rectangular jets so far. In this study, implicit large-eddy simulations are performed to analyse the noise control of supersonic rectangular jets with single- and double-bevelled nozzles. Three nozzle pressure ratios ($NPR = 2.3$, 3.0 and 5.0) are considered to form two over-expanded cold jets and one under-expanded cold jet, exhausted from a baseline convergent–divergent rectangular nozzle with an aspect ratio of 2.0. Results show that, with the increase of $NPR$, the oscillation of the jet plume is switched from a symmetrical mode to a flapping mode (preferential in the minor-axis plane), then to a helical mode, together with a reduction of the screech frequency. The amplitude of the screech tone is the strongest in the flapping jet, and the turbulent mixing noise is the most prominent in the helically oscillating jet. The single-bevelled nozzle induces asymmetric shock-cell structures and deflects the jet plumes, and the double-bevelled nozzle primarily enables the enhancement of the shear-layer mixing and shortens the lengths of the jet potential cores. With the bevelled nozzles, the gross thrusts of the baseline nozzle are increased by $0.05 \sim 7.38$ %. Details on the characteristics of far-field noise in the jets with/without the bevel cuts and their noise control mechanisms are discussed using the Ffowcs Williams–Hawkings acoustic analogy, dynamic mode decomposition and spatio-temporal Fourier transformation. Results suggest that the noise control has a close relationship with the destruction of well-organized coherent structures and the suppression of upstream-propagating guided-jet modes, which interrupt the feedback mechanism accounting for the generation of screech tones in the supersonic rectangular jets.
In this paper, we study the rapid transition in Richtmyer–Meshkov instability (RMI) with reshock through three-dimensional double-layer swirling vortex rings. The rapid transition in RMI with reshock has an essential influence on the evolution of supernovas and the ignition of inertial confinement fusion, which has been confirmed in numerical simulations and experiments in shock-tube and high-energy-density facilities over the past few years. Vortex evolution has been confirmed to dominate the late-time nonlinear development of the perturbed interface. However, few studies have investigated the three-dimensional characteristics and nonlinear interactions among vortex structures during the transition to turbulent flows. The coexistence of co-rotating and counter-rotating vortices is hypothesized to induce successive large-scale strain fields, which are the main driving sources for rapid development. The three-dimensional effect is reflected in the presence of local swirling motion in the azimuthal direction, and it decreases the translation velocity of a vortex ring. Large-, middle- and small-scale strain fields are employed to describe the development process of RMI with reshock, e.g. vorticity deposited by the reshock, formation of the coexistence of the co-rotating and counter-rotating vortices, iterative cascade under the amplification of the strain fields and viscous dissipation to internal energy. This provides theoretical suggestions for designing practical applications, such as the estimation of the hydrodynamic instability and mixing during the late-time acceleration phase of the inertial confinement fusion.
Traditional bulky and complex control devices such as remote control and ground station cannot meet the requirement of fast and flexible control of unmanned aerial vehicles (UAVs) in complex environments. Therefore, a data glove based on multi-sensor fusion is designed in this paper. In order to achieve the goal of gesture control of UAVs, the method can accurately recognize various gestures and convert them into corresponding UAV control commands. First, the wireless data glove fuses flexible fiber optic sensors and inertial sensors to construct a gesture dataset. Then, the trained neural network model is deployed to the STM32 microcontroller-based data glove for real-time gesture recognition, in which the convolutional neural network-Attention mechanism (CNN-Attention) network is used for static gesture recognition, and the convolutional neural network-bidirectional long and short-term memory (CNN-Bi-LSTM) network is used for dynamic gesture recognition. Finally, the gestures are converted into control commands and sent to the vehicle terminal to control the UAV. Through the UAV simulation test on the simulation platform, the average recognition accuracy of 32 static gestures reaches 99.7%, and the average recognition accuracy of 13 dynamic gestures reaches 99.9%, which indicates that the system’s gesture recognition effect is perfect. The task test in the scene constructed in the real environment shows that the UAV can respond to the gestures quickly, and the method proposed in this paper can realize the real-time stable control of the UAV on the terminal side.