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Boat-based metaphors, which portray individual societies or even humanity as a whole as cast adrift on a sea of challenges, have resonated within political theory since the time of Plato, and they continue to frame how we understand and respond to key political choices. However, unless handled very carefully, they can facilitate mis-framings of our contemporary predicament. To date, these metaphors have often done a poor job of capturing the ecological challenges we face. They also risk downplaying the messy pluralism that enduringly characterises political life. If this is true, we should be suspicious of the conclusions their authors seek to draw about our collective future. Lifeboat metaphors, I will suggest, are prone to the same general problems but also add some distinctively their own. As a consequence they should be deployed with especial caution.
The incorporation of trace metals into land snail shells may record the ambient environmental conditions, yet this potential remains largely unexplored. In this study, we analyzed modern snail shells (Cathaica sp.) collected from 16 sites across the Chinese Loess Plateau to investigate their trace metal compositions. Our results show that both the Sr/Ca and Ba/Ca ratios exhibit minimal intra-shell variability and small inter-shell variability at individual sites. A significant positive correlation is observed between the shell Sr/Ca and Ba/Ca ratios across the plateau, with higher values being recorded in the northwestern sites where less monsoonal rainfall is received. We propose that shell Sr/Ca and Ba/Ca ratios, which record the composition of soil solution, may be controlled by the Rayleigh distillation in response to prior calcite precipitation. Higher rainfall amounts may lead to a lower degree of Rayleigh distillation and thus lower shell Sr/Ca and Ba/Ca ratios. This is supported by the distinct negative correlation between summer precipitation and shell Sr/Ca and Ba/Ca ratios, enabling us to reconstruct summer precipitation amounts using the Sr/Ca and Ba/Ca ratios of Cathaica sp. shells. The potential application of these novel proxies may also be promising for other terrestrial mollusks living in the loess deposits globally.
Convection in planetary environments is often modelled using stress-free boundary conditions, with diffusion-free geostrophic turbulence scalings frequently assumed. However, key questions remain about whether rotating convection with stress-free boundary conditions truly achieves the diffusion-free geostrophic turbulence regime. Here, we investigated the scaling behaviours of the Nusselt number ($Nu$), Reynolds number (${Re}$) and dimensionless convective length scale ($\ell /H$, where $H$ is the height of the domain) in rotating Rayleigh–Bénard convection under stress-free boundary conditions within a Boussinesq framework. Using direct numerical simulation data for Ekman number $Ek$ down to $5\times 10^{-8}$, Rayleigh number $Ra$ up to $5\times 10^{12}$, and Prandtl number $Pr = 1$, we show that the diffusion-free scaling of the heat transfer $Nu - 1 \sim Ra^{3/2}\, Pr^{-1/2}\, Ek^2$ alone does not necessarily imply that the flow is in a geostrophic turbulence regime. Under the stress-free conditions, ${Re}$ and $\ell /H$ deviate from the diffusion-free scalings, indicating a dependence on molecular diffusivity. We propose new non-diffusion-free scaling relations for this diffusion-free heat transfer regime with stress-free boundary conditions: $\ell /H \sim Ra^{1/8}\, Pr^{-1/8}\, Ek^{1/2}$ and ${Re} \sim Ra^{11/8}\, Pr^{-11/8}\, Ek^{3/2}$. Our findings highlight the need to assess both thermal and dynamic characteristics to confirm geostrophic turbulence.
Ultra-processed food (UPF) consumption varies with socio-economic status (SES) in adults, and evidence suggests that similar patterns exist in adolescents. However, the relationship remains understudied in this critical developmental group. This study aimed to further characterise adolescent UPF consumption and its relationship with SES by exploring dietary patterns within UPF consumption.
Design:
Using food-diary data, adolescents’ UPF intake was quantified and categorised. Principal component and clustering analysis were used to identify dietary patterns. Associations of these dietary patterns with socio-demographic characteristics were then analysed.
Setting:
Pooled data from the rolling, cross-sectional National Diet and Nutrition Survey, waves 1-to-11 (2008–2019).
Subjects:
UK adolescents (11- to18-year-olds) (n 3199).
Results:
Three UPF dietary patterns were identified: (i) the ‘Restrictive’ pattern, which included the lowest total consumption of UPF (95 % CI: 33·1, 34·9 % g/d), but elevated consumption of UPF often perceived as healthy, was associated with adolescents of a higher SES; (ii) the ‘Permissive’ pattern included 61·6 % g/d (95 % CI: 60·3, 63·0 % g/d) total UPF, dominated by ‘ready-to-eat,’ low nutrient-density UPF, and was associated with adolescents of a lower SES and (iii) the ‘Traditional’ pattern had moderate consumption of total UPF (95 % CI: 47·6, 50·9 % g/d) with higher intake of UPF used in home-cooking and had less distinct associations with SES.
Conclusion:
Results suggest that SES impacts both the amount and type of UPF consumed by adolescents in the UK, underscoring the importance of this factor when designing interventions. Distinct dietary patterns within adolescents’ high UPF diets have potential behavioural, nutritional and health implications.
We investigate radial and non-radial solutions to a class of (p, q)-Laplace equations involving weights. More precisely, we obtain existence and multiplicity results for nontrivial nonnegative radial and non-radial solutions, which extend results in the literature. Moreover, we study the non-radiality of minimizers in Hénon type (p, q)-Laplace problems and symmetry-breaking phenomena.
Dedicated to Professor Pavel Drábek on the occasion of his seventieth birthday
The Office of Human Research Protections and the National Academy of Sciences, Engineering, and Medicine (NASEM) recommend the return of individual research results (IRRs) to study participants as a strategy to build public trust in science. However, the feasibility of sharing IRRs is unclear. Within a National Institutes of Health (NIH) funded parent study about Long COVID, we embedded the My ILLInet RECOVER Return of Results study to explore clinician-level considerations (e.g., validity, actionability, recommendations for follow-up) about returning a clinically used biomarker for heart failure (N-terminal pro-B-type natriuretic peptide, (NT-proBNP) collected as part of the NIH RECOVER study protocol.
Approach:
Clinicians participated in a three-phase modified Delphi process that sought their input to guide appropriate follow up recommendations the research team should provide to research participants with an abnormal NT-proBNP.
Results:
Clinicians agreed that NT-proBNP results could be returned to study participants. However, consensus was not reached on specific NT-proBNP thresholds that warrant immediate medical attention versus general follow-up.
Discussion:
Lack of clinical context presents a challenge in returning IRRs. Clinicians expressed concerns about the potential harm caused by misinformation or misinterpretation of these findings. While the NASEM report offers guidance on communicating IRRs, careful consideration is essential to ensure that clinical uncertainty is conveyed clearly, minimizing the risk of misinterpretation.
Conclusion:
The feasibility of returning IRRs to study participants depends, in part, on sufficient clinical context for the information to be actionable.
The heterogeneity of chronic post-COVID neuropsychiatric symptoms (PCNPS), especially after infection by the Omicron strain, has not been adequately explored.
Aims
To explore the clustering pattern of chronic PCNPS in a cohort of patients having their first COVID infection during the ‘Omicron wave’ and discover phenotypes of patients based on their symptoms’ patterns using a pre-registered protocol.
Method
We assessed 1205 eligible subjects in Hong Kong using app-based questionnaires and cognitive tasks.
Results
Partial network analysis of chronic PCNPS in this cohort produced two major symptom clusters (cognitive complaint–fatigue and anxiety–depression) and a minor headache–dizziness cluster, like our pre-Omicron cohort. Participants with high numbers of symptoms could be further grouped into two distinct phenotypes: a cognitive complaint–fatigue predominant phenotype and another with symptoms across multiple clusters. Multiple logistic regression showed that both phenotypes were predicted by the level of pre-infection deprivation (adjusted P-values of 0.025 and 0.0054, respectively). The severity of acute COVID (adjusted P = 0.023) and the number of pre-existing medical conditions predicted only the cognitive complaint–fatigue predominant phenotype (adjusted P = 0.003), and past suicidal ideas predicted only the symptoms across multiple clusters phenotype (adjusted P < 0.001). Pre-infection vaccination status did not predict either phenotype.
Conclusions
Our findings suggest that we should pursue a phenotype-driven approach with holistic biopsychosocial perspectives in disentangling the heterogeneity under the umbrella of chronic PCNPS. Management of patients complaining of chronic PCNPS should be stratified according to their phenotypes. Clinicians should recognise that depression and anxiety cannot explain all chronic post-COVID cognitive symptoms.
This study examines geographic origins of basketry, animal and human grave offerings (including a feline trophy head, camelid bone instruments and human trophy heads) interred as grave goods at the cemetery of Uraca in the Majes Valley, Arequipa, Peru during the Early Intermediate Period to Middle Horizon (c. 100 bce–750 ce). We aim to identify whether any of these human or non-human beings or artifacts were non-local to the Majes Valley and explore the ontologically informed meanings underlying the incorporation of geographically distant beings and things into mortuary landscapes. We report new grave good 87Sr/86Sr (n = 36) relative to published data from Uraca human trophy heads and non-trophy individuals (n = 55). Defining the local 87Sr/86Sr range as the mean ±2σ of the non-trophy and non-camelid or small home-range fauna, we compare the proportions of non-local outliers between plant, animal and human grave-offering types. The 87Sr/86Sr range of all new samples is 0.70609–0.70954, encompassing the 87Sr/86Sr variability of much of southern Peru from the coast to the highlands. Nearly half of camelids, the feline trophy, most camelid whistles and one basketry sample were non-local, suggesting that assembling beings and things from both local and distant geographies was an important aspect of making the mortuary landscape.
In the highlands of northern Chile, research on industrial mining camps and agropastoral sites (estancias) shows the relevance of a contemporary archaeology perspective for studying the impacts of capitalist expansion, ruination and deindustrialisation for local Indigenous communities.
Social anxiety disorder (SAD) is one of the most prevalent co-occurring conditions amongst cognitively unimpaired autistic people. The evidence-based treatment for social anxiety known as cognitive therapy for SAD (CT-SAD) may to an extent be beneficial to autistic people, but adaptations for autistic people are recommended to increase its effectiveness. The present study aimed to co-produce and pilot an adapted SAD treatment protocol for autistic people based on the Clark and Wells (1995) model, including assessing its feasibility and acceptability. A bespoke 12-week CBT online group intervention was created to meet the needs of autistic people with a diagnosis of SAD. The treatment protocol was created collaboratively with autistic people. It was piloted with seven adult participants (three males, four females) with autism or self-identified autism who completed the group intervention targeting SAD symptoms. With regard to feasibility, we met our initial aims of recruiting our intended sample size of a minimum of six participants for the intervention with an attendance rate of at least 80% of sessions. The excellent completion and attendance rates, respectively 100% and 95%, indicate that the intervention was acceptable to our participants. These findings extend previous research and support the continued adaptation of CBT interventions for autistic people. Furthermore, the evidence of feasibility indicates that further study to evaluate the efficacy of this group intervention is warranted.
Key learning aims
(1) To reflect on social anxiety, autism and identify ways to improve the delivery of cognitive therapy for autistic people.
(2) To identify useful adaptations to cognitive therapy for autistic people.
(3) To learn how to deliver group cognitive therapy remotely for autistic people who present with social anxiety.
This article addresses classical issues in conversation analysis related to the overall structural organization of social interaction, achieved through opening and closing sequences. While the integrity and autonomy of social interaction are most often oriented to by participants in single interactions, the study of some institutional interactions shows that forms of porosity between encounters do exist, in which one encounter impinges on another. This is the case of encounters-in-a-series, in which a new encounter is opened as the previous is not yet closed. The article examines interactions in which participants orient to the preservation of the integrity of successive encounters, contrasted with cases in which the initiation of the opening of a new encounter happens during or before the closing of the previous, and discusses how and when this is treated as normatively delicate or not, within the participants’ local endogenous analysis of the overall structural organization of the interaction. (Social interaction, conversation analysis, multimodality, overall structural organization, opening, closing, encounters-in-a-series, porosity)
Recent advancements in data science and artificial intelligence have significantly transformed plant sciences, particularly through the integration of image recognition and deep learning technologies. These innovations have profoundly impacted various aspects of plant research, including species identification, disease detection, cellular signaling analysis, and growth monitoring. This review summarizes the latest computational tools and methodologies used in these areas. We emphasize the importance of data acquisition and preprocessing, discussing techniques such as high-resolution imaging and unmanned aerial vehicle (UAV) photography, along with image enhancement methods like cropping and scaling. Additionally, we review feature extraction techniques like colour histograms and texture analysis, which are essential for plant identification and health assessment. Finally, we discuss emerging trends, challenges, and future directions, offering insights into the applications of these technologies in advancing plant science research and practical implementations.
Cystic echinococcosis (CE) is a significant zoonotic helminthic disease with considerable public health and economic impact in endemic regions. We aimed to analyse the climatic and environmental factors affecting the human CE cases in North Khorasan Province, northeast Iran. Using a geographic information system, we map the addresses of 316 hospitalised CE patients from 2012 to 2022 and examined the influence of climatic variables, altitude, and land cover on CE case distribution. Data were analysed using logistic regression models. Most patients were female (58.9%) and aged 21–60 years (67.4%), with liver involvement being the most common (57.3%). The multivariate model identified urban settings, irrigated and dry farms, soil temperature, and humidity as the most important geoclimatic determinants, respectively. In contrast, gardens, moderate and excellent rangelands, minimum, maximum, and mean air temperatures, and rainfall were only found to be significant factors in univariate models. High-risk areas for CE include urban and suburban regions, surrounding fields, and pastures where stray dogs and wild canids roam, livestock husbandries are present, and residents consume unsanitised vegetables. Additionally, areas with lower soil and weather temperatures and higher humidity conditions that may enhance the survival of E. granulosus eggs dispersed by canids were identified as high-risk zones. Health managers can use these findings to prioritise control programs and allocate limited resources to these areas, ultimately reducing the future incidence of CE.