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This article addresses the limited understanding of how variegated practices of everyday automobility shape – and are shaped by – ageing processes of older adults in urban contexts, focusing on Brescia, Northern Italy. While automobility, driving and driving cessation are often studied as functional aspects of older adults’ (im)mobility, their relational dimensions – spanning multiple and diverse practices – remain largely under-explored. The research examines how older adults navigate the contradictions and challenges of urban life, health conditions and social structures through relational automobilities. Drawing on an ongoing ethnographic study, the article highlights how automobility serves simultaneously as a resource, a limitation and a medium for forging and sustaining social, emotional, geographical and material relationships. The findings reveal that diverse practices and experiences of automobility are deeply embedded in affective economies, interdependencies and the biopolitics of ageing, shaping – and being shaped by – the lived experiences of older adults. By conceptualizing automobility as a socio-material and relational process, the article aims at bridging critical gerontology and mobilities studies, offering new insights into how ageing and mobility practices co-produce ageing selves and conditions of being (im)mobile. This study contributes to ongoing debates in critical gerontology by problematizing dichotomic understandings of older adults’ experiences in terms such as independence versus dependence and mobility versus stasis, while also informing urban policies aimed at fostering inclusive mobility practices. This article emphasizes the need to address the socio-material and relational networks underpinning automobility, offering a nuanced perspective on the interplay between mobility, ageing and urban life.
We review our recent ConfliBERT language model (Hu et al. 2022 [ConfliBERT: A Pre-Trained Language Model for Political Conflict and Violence]) to process political and violence-related texts. When fine-tuned, results show that ConfliBERT has superior performance in accuracy, precision, and recall over other large language models (LLMs) like Google’s Gemma 2 (9B), Meta’s Llama 3.1 (7B), and Alibaba’s Qwen 2.5 (14B) within its relevant domains. It is also hundreds of times faster than these more generalist LLMs. These results are illustrated using texts from the BBC, re3d, and the Global Terrorism Database. We demonstrate that open, fine-tuned models can outperform the more general models in terms of accuracy, precision, and recall, and at a fraction of the cost.
Dans la foulée des différentes vagues de mobilisation et de contestation des années 2010, les théories de la démocratie radicale ont permis de réfléchir à nouveaux frais au rapport des mouvements sociaux à la démocratie en les associant à un idéal d’insurrection populaire. Or, il découle de cette association une conception particulière de la conflictualité politique qui est susceptible de renoncer aux promesses pratiques et normatives de la démocratie. S’agissant de dépasser cette conception de la conflictualité politique et de réaffirmer la spécificité de l’apport démocratique des mouvements sociaux, cet article entend étayer l’hypothèse d’une institution insurgeante de la démocratie en soutenant que les mouvements sociaux contribuent par leurs pratiques contestataires à produire et à transformer l’ordre démocratique.
Telomere length is a biomarker of ageing, with shorter lengths associated with a higher risk of age-related diseases and mortality. Oxidative stress and inflammation predominantly contribute to telomere shortening. Diets rich in antioxidant and anti-inflammatory properties may help preserve telomere length. Nuts and seeds contain antioxidant and anti-inflammatory nutrients and bioactive compounds. Their consumption is recognised as protective against age-related conditions. The objective of this review is to evaluate the role of nut and seed intake on telomere length in humans. A systematic search was conducted in four databases from inception to 12 March 2024 to identify observational and interventional studies assessing nut and seed intake and measuring telomere length as an outcome in adults (aged ≥ 18 years). Data from the included articles were extracted by one reviewer and verified by another reviewer. Out of the nine observational studies included, three reported positive associations between nut and seed intake and telomere length. None of the four interventional studies included reported a significant positive effect. Meta-analysis was not performed due to high variability in reporting telomere length measurements. The evidence is insufficient to confirm a beneficial role of nut and seed intake on telomere length. Adequately powered long-term intervention studies are needed.
Muscular dystrophy (MD) encompasses inherited myopathies characterised by progressive skeletal and cardiac muscle degeneration, chronic inflammation and metabolic dysfunction. While emerging therapies show pre-clinical promise, few reach clinical translation, highlighting the need for supportive interventions to improve function and quality of life (QoL). Nutritional strategies may offer such benefits; however, limited data exist characterising diet in MD or associations with functional outcomes. This study assessed diet, nutritional status and associations with muscle strength, function and QoL in MD adults. Adults with MD (n 39; FSHD = 8, LGMD = 9 and Other = 22) and matched Controls (n 17) completed two 3-d food records, strength/function assessments and QoL questionnaires. Between-group differences were analysed using t tests or Mann–Whitney U and associations using Pearson’s r or Spearman’s Rho (P < 0·05). Compared with controls, individuals with MD consumed more energy (89 % v. 35 % exceeded RDI, P = 0·023), but less carbohydrate (–21 %, P = 0·013), sugar (–31 %, P = 0·004), protein (–15 %), BCAA (–31 %, P = 0·049) and vitamin C (–43 %, P = 0·009). MD participants demonstrated reduced muscle thickness, strength, function and reported lower QoL and physical capacity (all P < 0·05). Protein intake positively correlated with strength and function (P < 0·05); branched-chain amino acids intake was associated with lean mass (r = 0·442, P = 0·02) and strength (r = 0·372, P = 0·036). Findings indicate adults with MD consume excess energy but insufficient protein and micronutrients, supporting the need for adult MD-specific dietary guidance to optimise musculoskeletal health and QoL.
Infective endocarditis is a leading cause of morbidity and mortality in children and adolescents with underlying CHD. Appropriate diagnostic workup and management in the inpatient setting can be challenging in this patient population due to the spectrum of disease complexity and the dynamic nature of the field. Therefore, the Paediatric Acute Care Cardiology Collaborative has undertaken the creation of this clinical practice guideline.
Methods:
A panel of paediatric cardiologists, infectious disease specialists, intensivists, advanced practice practitioners, pharmacists, cardiothoracic surgeons, and a dentist was convened. The literature was systematically reviewed for relevant articles on the management of infective endocarditis in patients with CHD. Using the modified Delphi technique, recommendations were generated and put through iterative Delphi rounds to achieve consensus for inclusion.
Results:
Based on 127 articles that met the inclusion criteria, 82 recommendations were generated, 50 of which achieved consensus for inclusion and are included in this guideline. They address risk factors specific to CHD lesion type and prior interventions including implanted material, diagnostic considerations, management strategies, and recommendations on counselling other healthcare providers, patients, and families. Of the 50 consensus recommendations, 36 are strong recommendations, though 20 have low or very low quality of evidence.
Conclusions:
A central theme in this guideline is that an individual’s specific CHD lesion and prior interventions must be carefully considered for risk stratification, diagnostic approach, and management. While most are strong recommendations, many are supported by low quality of evidence, emphasising the need for further research in this subject.
Dans cet article, je soutiens que les dynamiques de boys club peuvent être comprises comme des instances d’actions collectives, même en l’absence d’intentions partagées. Il n’est pas satisfaisant de penser ces phénomènes comme de simples accumulations d’actions individuelles isolées. Une théorie minimaliste de l’action collective nous permet de considérer qu’il s’agit bien d’un phénomène d’action collective : l’ordre social patriarcal offre un plan d’action, qui oriente et coordonne les comportements des agents. C’est en vertu de cette coordination qu’on peut parler d’action collective.
In Julia Maskivker’s recent “Justice and Contribution,” she argues that, under normal circumstances, the failure to guarantee that life-sustaining workers are above the non-struggle point is not merely disrespectful and a failure of beneficence, but a violation of the norms of fair play and, as such, a “low blow.” In this article, I offer a critical reply to Maskivker. I begin by explaining her reasoning. Then I turn to critique, focusing on two key weaknesses and, in so doing, drawing out two larger lessons.
I argue for a general conception of justice that aims to identify what is common to multiple complementary types of justice. John Rawls agrees that there are multiple types (or “levels” or “subjects”) of justice, each needing its own principles, but he opposes a general conception in favour of “unity by appropriate sequence.” I present my general conception — justice as environment-shaping responsibility — as a different path to theoretical unity in a multi-type view of justice. I show how my general conception of justice can be arrived at through a process of generalizing that starts with Rawls’s conception of domestic justice.
Polynomial Julia sets with tree structure, typically Hubbard trees, play an important role in holomorphic dynamics. In this paper, we study the dynamics of ${f_\alpha (z)=z^2+\alpha \bar {z}}$ for $\alpha $ being real and the Julia sets being trees. We show that all such $\alpha $ form an interval $[1,4]$. This answers a question of G. Sienra. We further show that $f_\alpha $ exhibits non-trivial dynamics on the Fatou set which equals to the escaping set.
This article addresses two objections by Samuel Kahn to my argument for a living wage for life-sustaining workers. First, it refutes the charge that my position is patronising for asserting that low wages impede a worker’s ability to thrive. Second, it responds to a challenge regarding the claim that individuals have a right to a monetary equivalent of their fair share of natural resources, and that this right can be used to determine the justice of a life-sustaining worker’s situation in modern society.
This prospective study investigated the associations of various diet quality indices with mortality in Japan. Participants were 13 355 men and 15 724 women from the Takayama study. Eight diet quality indices were assessed using an FFQ: the Dietary Approaches to Stop Hypertension, alternative Mediterranean diet scores, Healthy Eating Index-2015, Alternate Healthy Eating Index-2010, Nutrient Rich Food Index 9.3, Diet Quality Score for Japanese, Japanese Food Guide Spinning Top and twelve-item Japanese Diet Index. Cox proportional models estimated hazard ratios and 95 % CI for all-cause and cause-specific mortality in a 1 sd difference for each index, with adjustment for confounders. During a mean follow-up of 14·1 years, 5339 deaths were recorded. Hazard ratios (95 % CI) per 1 sd higher index were 0·90 (0·87, 0·93) for Alternate Healthy Eating Index-2010, 0·92 (0·89, 0·95) for Diet Quality Score for Japanese, 0·93 (0·91, 0·96) for Nutrient Rich Food Index 9.3, 0·94 (0·92, 0·97) for alternative Mediterranean diet and Dietary Approaches to Stop Hypertension, 0·94 (0·91, 0·97) for Japanese Food Guide Spinning Top, 0·94 (0·91, 0·98) for twelve-item Japanese Diet Index and 0·97 (0·94, 0·996) for Healthy Eating Index-2015. Similar protective associations were observed for CVD mortality, but not for cancer mortality. These findings suggest that all eight indices are associated with lower mortality and that the strength of associations varies across indices; the Alternate Healthy Eating Index-2010 showed relatively strong associations, followed by the Diet Quality Score for Japanese, whereas the associations of the Healthy Eating Index-2015 appeared relatively weaker in this Japanese population.
Inspired by a discourse-centred commodity chain analysis (Thurlow 2020), this study investigates beefy landscapes materialized in three organic grocery store chains in Germany. Organic food stores produce meat-intensive texts that may contradict their widely promoted and mediatized claims to sustainability, complicating the pleas for reducing meat consumption which is essential to limit global warming. Focusing on organic beef, with the largest climate footprint of any protein source, the study looks into semiotic material detached from scientific findings on environmental issues and composing an alarming part of the globalized clean food discourse that masks unsustainable realities. By putting forward cows as icons of organic cattle farming and the effortless convenience of preparation, while erasing environment-related impact categories, beef consumption is perpetuated. The article ultimately shows that our ‘meaty routines’ (Sundet, Hansen, & Wethal 2023) are deeply rooted in environmental escapism as we follow the hype to eat right. (Organic beef, Anthropocene discourse, semiotic landscape, discourse-centred commodity chain analysis, (Social) Life Cycle Assessment)