In the past, Vietnam was impacted by numerous epidemics, particularly during the Nguyễn Dynasty from 1802 to 1883. Based on data from the Đại Nam Thực Lục (1961) (The Veritable Records of the Great South), this article investigates the frequency and nature of these epidemics, identifies the types of common diseases at that time, and explores the underlying causes of these outbreaks. The study further examines the Nguyễn Dynasty's strategies for managing these health crises. During these outbreaks, the dynasty faced significant challenges, with frequent epidemics leading to high death rates, widespread social disruption, and economic decline. The dynasty's primary preventive measures, heavily reliant on spiritual practices like prayer, highlight the limited medical understanding at the time and the constraints of its socio-political framework. However, there was a progressive shift towards the incorporation of Western medical innovations, particularly in the vaccine approach to treat diseases like smallpox. This transition not only marked a critical evolution in the local healthcare approach but also set the stage for more systematic medical advancements in Vietnam during the colonial period (1884–1945).

We herein investigated the influence of temperature on the embryonic development (from fertilisation to hatching) of Mugil liza larvae. For this purpose, oocytes (>600 μm) and sperm were obtained from breeding stock at the laboratory of marine fish culture (LAPMAR). After fertilisation, 1200 eggs were distributed in 12 cylindrical experimental units of 400 mL under four different temperatures 18, 22, 26 and 30 ºC, all in triplicate. Every 15 min until hatching, about 10 eggs were randomly sampled in each treatment. The eggs were visualized and photographed, and the classification of embryonic stages was performed. Temperature influenced the main events of the embryonic development of M. liza. More accelerated development was observed according to the increase in temperature until the gastrula phase. At temperatures of 22 and 26 °C, embryonic development occurred from fertilisation to hatching of the larvae. In the 18 °C treatment, it was verified that most of the embryos ceased development during the final phase of cleavage and the beginning of blastula formation, while in the 30 °C treatment patterns of embryo malformation were also verified, with erratic divisions of the blastomeres, resulting in irregular cells. Unlike what was observed at a temperature of 18 °C, none of the embryos incubated at 30 °C reached the blastopore closure phase, stopping in the gastrula. The larvae hatched in the treatments at 22 and 26 °C were viable and exhibited intense swimming, with a large amount of reserve material (yolk) and an evident drop of oil.

It is well documented that Andean bears (Tremarctos ornatus) feed extensively on plants and carrion, but their hunting habits remain understudied. Better understanding and documentation of Andean bear feeding ecology can improve conservation efforts for this vulnerable species. Here, we report an observation of an Andean bear hunting and capturing a wild guinea pig (Cavia aperea) in Chingaza National Natural Park, in Cundinamarca, Colombia. The sighting occurred in January 2023 by a team of conservationists, and we provided photographic evidence and details of the encounter. Our observation suggests that Andean bears are capable hunters of small rodents, indicating that hunting may play a more important role in the ecology of Andean bears than previously appreciated and highlighting the need for a better understanding of this feeding behaviour.

Childhood adversities have been linked to psychosocial outcomes, but it remains uncertain whether subtypes of adversity exert different effects on outcomes. Research is also needed to explore the dynamic interplay between adversity and psychosocial outcomes from childhood to mid-adolescence. This study aimed to investigate these relationships and their role in shaping adolescent wellbeing. Data were extracted from three timepoints of the UK Household Longitudinal Survey when participants (n = 646) were aged 10–15. Cross-lagged panel models were used to explore the relationship between cumulative adversities, and separately non-household (i.e., bullying victimization and adverse neighborhood) and household (i.e., sibling victimization, quarrelsome relationship with parents, financial struggles, and maternal psychological distress) adversities, and psychosocial outcomes (i.e., internalizing and externalizing problems, delinquency, and life satisfaction). Our results revealed that heightened cumulative adversity predicted psychosocial outcomes from childhood to mid-adolescence. Increased levels of household adversity predicted psychosocial outcomes throughout early to mid-adolescence, while non-household adversity only predicted psychosocial outcomes in early adolescence. Furthermore, worse psychosocial outcomes predicted higher levels of adversities during adolescence, highlighting bidirectionality between adversity and psychosocial outcomes. These findings underscore the varying impacts of adversity subtypes and the mutually reinforcing effects of adversities and psychosocial functioning from childhood to mid-adolescence.

Why is parenting in adolescence predictive of maladaptive personality in adulthood? This study sets out to investigate environmental and genetic factors underlying the association between parenting and maladaptive personality longitudinally in a large sample of twins. The present study addressed this question via a longitudinal study focused on two cohorts of twins assessed on aspects of perceived parenting (parent- and adolescent-reported) at age 14 years (n =1,094 pairs). Participants were followed to adulthood, and maladaptive personality traits were self-reported using the Personality Inventory for DSM-5 (PID-5) at age 24 or 34 years. We then modeled these data using a bivariate biometric model, decomposing parenting-maladaptive personality associations into additive genetic, shared environmental, and nonshared environmental factors. Numerous domains of adolescent-reported parenting predicted adult maladaptive personality. Further, we found evidence for substantial additive genetic (ra ranging from 0.22 to 0.55) and (to a lesser extent) nonshared environmental factors (re ranging from 0.10 to 0.15) that accounted for the association between perceived parenting reported in adolescence and adult personality. Perceived parenting in adolescence and maladaptive personality in adulthood may be related due to some of the same genetic factors contributing to both phenotypes at different developmental periods.

We review and elaborate an account of consonantal strength that is founded on the model of speech as a modulated carrier signal. The stronger the consonant, the greater the modulation. Unlike approaches based on sonority or articulatory aperture, the account offers a uniform definition of the phonetic effect lenition has on consonants: All types of lenition (such as debuccalisation, spirantisation and vocalisation) reduce the extent to which a consonant modulates the carrier. To demonstrate the quantifiability of this account, we present an analysis of Ibibio, in which we investigate the effects of lenition on the amplitude, periodicity and temporal properties of consonants. We propose a method for integrating these different acoustic dimensions within an overall measure of modulation size. Not only does the modulated-carrier account cover all the classically recognised lenition types, but it also encompasses loss of plosive release in final stops – which, although not traditionally classed as lenition, is clearly related to processes that are.

In 1912, the Italian parliament approved the extension of male suffrage, making it ‘almost’ universal. This process of revising representation transformed the very idea of the relationship between citizens and the state and shaped a profoundly different Italy. The aim of this article is to trace both the process leading to the approval of universal suffrage and its impact on the party system. With a compilation and analysis of data developed from scratch for the elections of 1909 and 1913, it was possible to analyse the main dimensions of the two rounds in a disaggregated manner. Three aspects make 1913 a year of transition. First, the degree of competition in the electoral process, especially in the South, increased considerably. Second, the decline of liberal formations was not transformed into defeat, thanks only to the Catholic vote. Third, the birth of the Popular Party and the failure to create a mass party of conservatives were causes of the imbalance in the party structure.

Declining labor force participation of older men throughout the 20th century and recent increases in participation have generated substantial interest in understanding the effect of public pensions on retirement. The National Bureau of Economic Research's International Social Security (ISS) Project, a long-term collaboration among researchers in a dozen developed countries, has explored this and related questions. The project employs a harmonized approach to conduct within-country analyses that are combined for meaningful cross-country comparisons. The key lesson is that the choices of policy makers affect the incentive to work at older ages and these incentives have important effects on retirement behavior.

Plant–soil interactions have bottom–up and top–down effects within a plant community. Heavy metal pollution can change plant–soil interactions, directly influence bottom–up effects and indirectly affect herbivores within the community. In turn, herbivores can affect plant–soil interactions through top–down effects. However, the combined effects of heavy metals and herbivores on soil enzymes, plants and herbivores have rarely been reported. Therefore, the effects of lead (Pb), Spodoptera litura and their combined effects on soil enzyme activities, pakchoi nutrition, defence compounds and S. litura fitness were examined here. Results showed that Pb, S. litura and their combined effects significantly affected soil enzymes, pakchoi and S. litura. Specifically, exposure to double stress (Pb and S. litura) decreased soil urease, phosphatase and sucrase activities compared with controls. Furthermore, the soluble protein and sugar contents of pakchoi decreased, and the trypsin inhibitor content and antioxidant enzyme activity increased. Finally, the S. litura development period was extended, and survival, emergence rates and body weight decreased after exposure to double stress. The combined stress of Pb and S. litura significantly decreased soil enzyme activities. Heavy metal accumulation in plants may create a superposition or synergistic effect with heavy metal-mediated plant chemical defence, further suppressing herbivore development. Pb, S. litura and their combined effects inhibited soil enzyme activities, improved pakchoi resistance and reduced S. litura development. The results reveal details of soil–plant–herbivore interactions and provide a reference for crop pest control management in the presence of heavy metal pollution.

Studies have found that women’s representation is more likely to spike after corruption scandals. However, the mechanism underlying this increase remains unclear: are parties more likely to nominate women after corruption scandals, are voters more likely to support women candidates, or is it a combination of both? Using an original dataset of audit results and the gender of 47,000 candidates running in over 10,000 mayoral elections in Mexico (2000–2019), we find that voters drive the effect. While political parties are not more likely to nominate women as candidates in municipalities with recent revelations of spending irregularities, women candidates are more likely to win elections after corruption is uncovered. In contrast to previous studies, which expect strategic parties to be behind the increases in women’s representation following corruption scandals, our findings underscore that increases in women’s representation can happen despite parties and not because of parties.