The Dorchester Aqueduct, located to the north-west of Dorchester (Durnovaria) in Dorset, is arguably the most famous and well-examined Roman watercourse in Britain. The aqueduct has been intermittently investigated over the course of the last 100 years, but most extensively during the 1990s. The upper stretches of the aqueduct and its source have, however, eluded archaeologists, with multiple routes and water sources being suggested. A new programme of geophysical and topographic survey, combined with targeted investigation together with a reappraisal of the excavations from the 1990s, has provided additional evidence for the route of the aqueduct, extending its course for a further two kilometres to Notton on the River Frome.

This article presents the results of the 2008 excavation in the ancient theatre of Sparta conducted by the British School at Athens and the Ephorate of Antiquities of Laconia. Focused on the west side of the cavea, work aimed to locate the southern edge of the Late Antique settlement between the theatre and the sanctuary of Athena Chalkioikos; to establish the northern limits of the Late Antique settlement over the former orchestra; and to establish a more precise ceramic characterisation and chronology for the Early–Middle Byzantine period in Sparta. The area between settlement clusters on the acropolis and over the former orchestra was essentially open, with just a Byzantine terrace wall and path recorded. In the north-west part of the former cavea, a tomb built in the late eighth or early ninth century AD was used at least until the late thirteenth century for the burial of c. 29 individuals. This article presents the first results of a bioarchaeological study of the human remains, and studies of Byzantine pottery from the tomb interior and from the backfill of the pit in which the tomb was built (the latter including a notable quantity of Early Byzantine domestic ware). The 2008 findings are set in the larger context of research on post-antique phases in the theatre (drawing on the British School at Athens Archive) and on the material culture and urban topography of Byzantine Sparta. Almost all excavated contexts contained residual material of all periods. The article concludes with short catalogues of material which pre-dates the construction of the theatre and of inscriptions of all periods.

For any $n<\omega $ we construct an infinite $(n+1)$-generated Heyting algebra whose n-generated subalgebras are of cardinality $\leq m_n$ for some positive integer $m_n$. From this we conclude that for every $n<\omega $ there exists a variety of Heyting algebras which contains an infinite $(n+1)$-generated algebra, but which contains only finite n-generated algebras. For the case $n=2$ this provides a negative answer to a question posed by G. Bezhanishvili and R. Grigolia in [4].

The authors of this book are archaeologists who want to create a field they describe as ‘critical paleoeconomics’. Their quest is promising in several ways. For example, they are not averse to grand narratives and believe modern economic theory can offer insights into various features of ancient economies, including markets, trade, money and debt.

In recent years, dangerous gas leakage events occur frequently. Rapid and accurate location of gas leakage sources by mobile robots is the key to avoid the expansion of disasters. In order to solve the problem of discontinuous gas concentration gradient and sparse gas environment in three-dimensional space, particle filter, and whale swarm optimization algorithm are integrated to locate gas source. Firstly, the Z-shape search and comb search are used to locate the plume, and then, the particle filter algorithm is combined with the whale optimization method to guide the particle movement, and the random inertial disturbance term is designed to improve the convergence speed and search accuracy of the algorithm. Experimental results in three-dimensional environment show that the proposed information-driven particle filter whale optimization hybrid algorithm effectively guides the robot in localizing gas source within a certain range, significantly enhancing both the efficiency and accuracy of localization compared to other algorithms.

Species in the genus Engraulis show extensive intraspecific as well as interspecific morphological and genetic diversity. Since morphological differences do not necessarily correspond to genetic differences, it is necessary to clarify the relationship between morphological differences and genetic differences for a better understanding of the population structure. Fish morphology at a given standard length differs between cohorts of Japanese anchovy Engraulis japonicus during the early life stages in the Kii Channel, but it is unknown whether the differences are caused by genetic differences or not. The Kii Channel includes the boundary between the Pacific (southern side of the Kii Channel) and the Seto Inland Sea stocks (northern side), but stock separation is based primarily on demographic characteristics. In the present study, genetic analyses were conducted to examine the genetic differences among samples (month and area) based on mitochondrial DNA cytochrome b region (Cyt b), control region (CR) and microsatellite markers. AMOVA revealed that the percentage of genetic variation among samples was low at 0.11% for Cyt b, 0.30% for CR and 0.00% for microsatellite, and no significant genetic variation was observed among samples. Although two clades were identified in the unrooted neighbour-joining tree for Cyt b and CR, both Cyt b and CR sequences were similar between months and between areas. Accordingly, the morphological differences among cohorts can be attributed to phenotypic plasticity. Additionally, there were no genetic differences between samples from the southern side and the northern side of the Kii Channel, suggesting strong genetic connectivity in these areas.

This study examined the efficacy of a probiotic in reducing depressive symptom severity in people with subthreshold depression. In a double-blind, randomised, placebo-controlled trial, a probiotic (1 × 10^9 live cells per strain: Limosilactobacillus fermentum LF16 (DSM26956), Lacticaseibacillus rhamnosus LR06 (DSM21981), Lactiplantibacillus plantarum LP01 (LMG P-21021) and Bifidobacterium longum 04 (DSM23233)) or placebo was taken daily for 12 weeks. Data were collected at baseline, 6 and 12 weeks including psychological symptom severity (Beck Depression Inventory, BDI; Patient Health Questionnaire, PHQ; Hospital Anxiety Depression Scale, HADS; and Depression Anxiety and Stress Scale, DASS). Biomarkers of glycaemia, inflammation (high-sensitivity C-reactive protein, hs-CRP), antioxidant status (total glutathione (GSH)) and stress (cortisol awakening response, CAR) were also measured. Thirty-nine participants (nineteen probiotic; twenty placebo) were enrolled. There were no significant between-group differences in the examined psychological symptom severity scores, despite certain significant within-group changes observed in both groups from baseline to 6 and/or 12 weeks of follow-up. Regarding biomarkers, the probiotic group showed reduced hs-CRP (–1520; 95 % CI –273·7, −2766·2 ng/dl) and CAR (–0·28; 95 % CI −0·05, −0·51 μg/dl) at 12 weeks, but increased total GSH (3·9; 95 % CI 0·1, 7·5 ng/dl) at 6 weeks, compared with the placebo. The current study reported favourable decreases in depressive symptoms in both groups. Although the within-group changes observed in the probiotic group were supported by favourable inflammatory, antioxidant status and stress biomarker changes compared with the placebo, further research is required to shed more light on the role of gut microbiota modulation on emotional regulation.

The relationship between Schistosoma mansoni (Sm) and hepatocellular carcinoma (HCC) has been evaluated by many studies that point towards a co-relation between schistosomal infection and HCC. While many such studies demonstrated that Sm infection in the presence of another carcinogenic factors leads to HCC, none of these studies could conclusively prove the cancer-inducing ability of Sm in humans, independent of other carcinogenic factors. The aim of this work is to present the current understanding on the association of Sm with HCC. Many epidemiological, pathological, and clinical studies have shown the role of multiple events like chronic inflammation and fibrosis as well as hepato-toxic agents like soluble egg antigens (SEAs), which help in creating a micro-environment which is suitable for HCC development. The role of Sm infection and deposited eggs in causing persistent inflammation, advanced fibrosis, and the role of SEAs, especially IPSE/alpha-1, is emphasised. This work concludes that Sm infection has the potential to induce cancer independently but the same has not been reported in humans to date. Extensive research is required to establish a causal relationship between Sm infection and HCC induction, or a complete lack thereof. However, Sm infection definitely acts along with other carcinogenic factors to induce HCC at a much faster pace and also leads to an aggressive form of liver cancer, which the other carcinogenic factor could not have achieved alone.

This article presents a comprehensive evaluation of two nuclear-rated bilateral telerobotic systems, Telbot and Dexter, focusing on critical performance metrics such as effort transparency, stiffness, and backdrivability. Despite the absence of standardized evaluation methodologies for these systems, this study identifies key gaps by experimentally assessing the quantitative performance of both systems under controlled conditions. The results reveal that Telbot exhibits higher stiffness, but at the cost of greater effort transmission, whereas Dexter offers smoother backdrivability. Furthermore, positional discrepancies were observed during the tests, particularly in nonlinear positional displacements. These findings highlight the need for standardized evaluation methods, contributing to the development, manufacturing, and procurement processes of future bilateral telerobotic systems.

We show that there exists a recursive coloring function c such that any $\Pi ^0_3$ set is not a solution to c for Hindman’s theorem. We also show that there exists a recursive coloring function c such that any $\Delta ^0_3$ set is not a solution to c for Hindman’s theorem restricted to sums of at most three numbers.

To explore relationships between spatial distributions of northern shrimp Pandalus eous and environmental factors along the coastline of Honshu Island in the Sea of Japan, we built delta-type two-step generalized additive models (delta-GAM) based on bottom trawl surveys conducted in 2013–2022. The models provide the first quantitative analysis of the species’ habitat, showing that its distribution is associated with bottom sediment type, depth, slope and topographic position index (TPI) alongside the effects of year and region. From the delta-GAM response plots, species habitat preferences in the Sea of Japan were estimated as follows: seafloor deeper than 283 m; muddy rather than sandy bottoms; gently sloped to flat bottoms (<0.8° in slope); and valleys rather than ridges (TPI < 0.9). These results were reviewed in detail along with previously reported distribution records of northern shrimp. Standardized density (s-density) per fishing grid cell (10′ square latitude–longitude mesh) estimated from the delta-GAM results indicated that this species is widely distributed on the continental slope along the coast of Honshu Island. To test plausibility of the s-density analysis, we compared s-density per fishing grid cell with nominal CPUE (kg per haul) per fishing grid cell based on official logbook data from large offshore trawl fisheries. The two were generally positively correlated by year, and the delta-GAM results were assumed to be fairly robust. Finally, potential fishing grounds were explored based on the delta-GAM results.

This study presents the first Korean records of two subtropical fish species, Pseudojuloides paradiseus and Diplogrammus xenicus, collected around Jeju-do Island, as well as one boreal fish species, Erilepis zonifer, collected in Busan (approximately 200 km away from Jeju-do Island). In this study, we discuss the implications of the species’ habitat range expansion. Previously, P. paradiseus was known as an endemic species of Japan, while D. xenicus was known to inhabit the Eastern Indian Ocean and the Pacific Ocean excluding around the equator, and E. zonifer was only known to inhabit the Pacific Ocean between eastern Japan and the western USA. Their habitat range expansions might be attributed to the expansion of the Tsushima Warm Current at the surface layer and/or the North Korean Cold Current at the bottom layer. Our findings may suggest that habitat of marine fish is being changed continuously by climate change or oceanic currents. Therefore, it needs to conduct integrated and systematic monitoring of fish fauna to response changing marine biodiversity.

Although mesopelagic fish dominate the oceanic ecosystem, they remain one of the least investigated components. From the vertically stratified sample collections, we investigated community structure, vertical distribution and diel/ontogenetic vertical migration covering four seasons for larval and juvenile/adult mesopelagic fish at the time-series station K2 in the Western Subarctic Gyre of the North Pacific. We collected 10 and 20 species of larval and juvenile/adult fish, respectively. Among the larval fish community, Leuroglossus schmidti was the most abundant; total abundances except L. schmidti were low throughout the year; species richness of myctophids were low. Among the 20 species of juvenile/adult fish, larvae of only six species were collected; thus, most mesopelagic fish species do not use the Western Subarctic Gyre as their nursery. In the juvenile/adult fish community, Stenobrachius leucopsarus and Stenobrachius nannochir were abundant. Species diversity and total abundance in the warm seasons (summer and autumn) were higher than in the cold seasons (winter and spring). The decreasing of species diversity and total abundance during the cold seasons was probably affected by horizontal migrations of fish for reproduction toward the southern transition or subarctic slope areas. Stenobrachius leucopsarus was distributed at shallow depths with opportunistic diel vertical migration (DVM); in contrast Stenobrachius nannochir occurred at greater depths, without DVM. The distribution depths of S. leucopsarus during day and those of S. nannochir changed seasonally and synchronously; shallowest in autumn, deepest in spring.

This study provides the first records of the upside-down jellyfish Cassiopea andromeda (Forskål, 1775) in the eastern Atlantic supported by molecular analysis. Specimens were observed, recorded, and sampled in an inland aquaculture facility in September 2023 in Tenerife Island (Canary Islands). This new record officially demonstrates the geographical expansion of C. andromeda, and the introduction of a new potential invasive species in the Macaronesia oceanic island system.

Epidemiological evidence suggests that a higher intake of sugar during pregnancy is associated with a higher risk of childhood asthma and atopy. However, randomised trial evidence supporting such a link is lacking. This study aimed to examine whether a low glycaemic index (GI) dietary intervention during pregnancy decreases the risk of childhood asthma and eczema. This is a secondary analysis of 514 children from the ROLO trial. Healthy women were randomised to receive an intervention of low GI dietary advice or routine care from early pregnancy. Mothers reported current doctor-diagnosed eczema in their children at 2 years (n 271) and current doctor-diagnosed asthma and eczema in their children at 5 (n 357) and 9–11 years (n 391) of age. Multivariable logistic regression models were used test the effect of the intervention on child outcomes overall and stratified by maternal education. There was a suggestion of a reduction in asthma at 5 years of age in children whose mothers received the low GI dietary intervention during pregnancy compared with usual care (adjusted OR 0·46 (95 % CI 0·19, 1·09); P = 0·08). In stratified adjusted analyses, the intervention was associated with a reduced risk of asthma at 5 years of age in children born to mothers with incomplete tertiary level education but not in those with complete tertiary level education (OR 0·14 (95 % CI 0·02, 0·69); P = 0·010 and OR 1·03 (95 % CI 0·34, 3·13); P = 0·94, respectively). A low GI diet in pregnancy may reduce the risk of developing asthma in childhood, particularly amongst children born to mothers with lower educational attainment.