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Aoun and Li (2003) argued that whether the head of Chinese relative clauses can reconstruct at Logical Form is determined by its phrasal category. When the head is a noun phrase, it can reconstruct; but when it is a quantifier phrase, it cannot. This paper uses a sentence-picture matching experiment to investigate this claim. The results showed that a quantifier phrase can reconstruct. Thus, we do not need to stipulate a noun phrase/quantifier phrase distinction for the reconstruction of heads in Chinese relative clauses. Both types of phrases can reconstruct, predicted by the head-raising analysis of relative clauses.
The AMS Golden Valley radiocarbon analysis laboratory is equipped with two accelerator mass spectrometers: AMS facility from Budker Institute of Nuclear Physics (BINP AMS) and MIni CArbon DAting System (MICADAS-28) from Ionplus AG and two graphitization systems: Automated Graphitization Equipment (AGE-3) from Ionplus AG and Absorption-catalytic setup developed in Boreskov Institute of Catalysis (ACS BIC). The laboratory provides routine 14C analyses of various samples: collagen, cellulose, humic acids, carbonates from sediments, etc. The main focus of the laboratory is to determine the age of archaeological artifacts by radiocarbon dating. This work presents a comprehensive description of the BINP AMS facility, with its operation compared with that of MICADAS in the same laboratory. In 2022, the AMS Golden Valley laboratory participated for the first time in the Glasgow International Radiocarbon Inter-comparison (GIRI). The samples were graphitized on the AGE-3 and subsequently measured in both AMS facilities. A comparison of the results of the two series of experiments, namely AGE-3 + MICADAS-28 and AGE-3 + BINP AMS, is given.
Cerebral small vessel diseases (CSVDs) are among the most common age-related pathologies of the brain. Arteriolosclerosis and cerebral amyloid angiopathy (CAA) are the most common CSVDs. In addition to causing stroke and dementia, CSVDs can have diverse covert radiological manifestations on computed tomography and magnetic resonance imaging including lacunes, T2-weighted white matter hyperintensities, increased density of visible perivascular spaces, microbleeds and cortical superficial siderosis. Because they cannot be visualized directly, research on the pathophysiology of CSVD has been difficult. However, advances in quantitative imaging methods, including physiological imaging such as measurement of cerebrovascular reactivity and increased vascular permeability, are beginning to allow investigation of the early effects of CSVD in living people. Furthermore, genomics, metabolomics and proteomics have the potential to illuminate previously unrecognized pathways to CSVD that could be important targets for new clinical trials.
Tetralogy of Fallot is the most prevalent cyanotic CHD. With the advent of advanced surgical methods, the majority of tetralogy of Fallot patients reach adulthood. However, many need re-intervention for the residual anomalies including residual right ventricular outflow obstruction, pulmonary regurgitation, residual ventricular septal defects, and progressive aortic dilatation. Aortic dilation could lead to aortic regurgitation or dissection requiring surgical correction. In the current study, we aimed to determine the prevalence and outcomes of aortic root dilatation in adults with repaired tetralogy of Fallot in our tertiary care centre.
Methods:
In this retrospective study, 730 consecutive patients with history of repaired tetralogy of Fallot were included. Aortic diameter at the level of annulus, the sinus of Valsalva, sinotubular junction, and the ascending aorta as measured by echocardiography were evaluated. Prevalence of outcomes necessitating re-intervention including aortic regurgitation and dissection were recorded.
Results:
The mean size of annulus, sinus of Valsalva, sinotubular-junction, and ascending aorta in the latest available echocardiography of patients were 2.4+/-0.4 cm, 3.3+/-0.5 cm, 2.9+/-0.5cm, and 3.2+/-0.5cm, respectively. Prevalence of dilatation of sinus of Valsalva, dilation of Ascending aorta, sinotubular-junction, and aortic annulus was 28.7%, 21%, 8.3%, and 1 %, respectively. Five patients had severe aortic regurgitation (0.6%) and underwent surgical repair. One of these patients presented with acute aortic dissection.
Conclusion:
Aortic dilation is common in tetralogy of Fallot but prevalence of redo surgery for aortic dilation, regurgitation, and adverse events including acute dissection is low.
In this work, we study the existence of solutions of nonlinear fractional coupled system of $\varphi $-Hilfer type in the frame of Banach spaces. We improve a property of a measure of noncompactness in a suitably selected Banach space. Darbo’s fixed point theorem is applied to obtain a new existence result. Finally, the validity of our result is illustrated through an example.
The purpose of this study was to investigate the effect of an egg white hydrolysate (EWH) to protect white adipose tissue damage from cardiometabolic changes induced by severe hypertension. Male Wistar rats were uninephrectomised and divided: SHAM (weekly subcutaneous vehicle (mineral oil + propylene glycol, 1:1)), SHAM + EWH (subcutaneous vehicle plus EWH via gavage, 1 g/kg per day), DOCA (deoxycorticosterone acetate diluted in vehicle subcutaneously weekly in subsequent doses of 20 mg/kg -1st week, 12 mg/kg - 2–3th week, and 6 mg/kg -4–8th week, respectively, plus 1 % NaCl and 0·2 % KCl in drinking water), and DOCA + EWH. Body weight gain, food and water intake, glucose and lipid metabolism were evaluated. Oxidative stress was assessed by biochemical assay and immunofluorescence for NOX-1, nuclear factor kappa B (NFκB), and caspase-3 in retroperitoneal white adipose tissue (rtWAT). Proinflammatory cytokines (IL-6 and 1β), CD163+ macrophage infiltration, and immunohistochemistry for TNFα and uncoupling protein-1 were evaluated, as well as histological analysis on rtWAT. Glutathione peroxidase and reductase were also determined in plasma. EWH showed hypocholesterolemic, antioxidant, anti-inflammatory, and anti-apoptotic properties in the arterial hypertension DOCA-salt model. The results demonstrated the presence of functional changes in adipose tissue function by a decrease in macrophage infiltration and in the fluorescence intensity of NFκB, NOX-1, and caspase-3. A reduction of proinflammatory cytokines and restoration of antioxidant enzymatic activity and mitochondrial oxidative damage by reducing uncoupling protein-1 fluorescence intensity were also observed. EWH could be used as a potential alternative therapeutic strategy in the treatment of cardiometabolic complications associated with malignant secondary arterial hypertension.
Previous evidence has suggested that acoustic similarity between first language (L1) and second language (L2) sounds is an accurate indicator of the speakers’ L2 classification patterns. This study investigates this assumption by examining how speakers of an under-researched language, namely Cypriot Greek, classify L2 English vowels in terms of their L1 categories. The experimental protocol relied on a perception and a production study. For the purpose of the production study, two linear discriminant analysis (LDA) models, one with both formants and duration (FD) and one with only formants (F) as input, were used to predict this classification; the models included data from both English and Cypriot Greek speakers. The perception study consisted of a classification task performed by adult Cypriot Greek advanced speakers of English who permanently resided in Cyprus. The results demonstrated that acoustic similarity was a relatively good predictor of speakers’ classification patterns as the majority of L2 vowels classified with the highest proportion were predicted with success by the LDA models. In addition, the F model was better than the FD model in predicting the full range of responses. This shows that duration features were less important than formant features for the prediction of L2 vowel classification.
This study starts with a simple model by which Hardy-Weinberg proportions are attained in a single generation while maintaining gene frequencies. The question of differentiating between random and non-random mating is explored by simulation. Sample mating proportions are generated using the model as base. The difficulty of differentiating between random and non-random mating is illustrated.
We propose an efficient method to reconstruct the turbulent flow field in a neutrally stratified atmospheric boundary layer using large-eddy simulation (LES) and a series of lidar measurements. The reconstruction is formulated as a strong four-dimensional variational data assimilation problem, which involves optimizing two competing terms that contribute in the objective functional. The first term is a likelihood term, while the second contains the initial background distribution of turbulent velocity fluctuations and works as a regularization term. However, computing and storing the full background covariance tensor in turbulent flows is time consuming and resource intensive. In the current work, we investigate the possibility of replacing the complex background tensor by simple analytical approximations based on spectral tensors such as the Hunt–Graham–Wilson (HGW) model (Boundary-Layer Meteorol., vol. 85, 1997, pp. 35–52) or the Mann model (J. Fluid Mech., vol. 273, 1994, pp. 141–168). Afterwards, the problem is solved using a quasi-Newton algorithm and preconditioned to enhance the convergence rate. We test the method using virtual lidar measurements collected on a fine reference LES. Results show a super-linear convergence rate of the optimization algorithm to a local minimum and very good agreement between virtual lidar measurements and reconstruction in the scanning region. Furthermore, we demonstrate that incorporating the Saffman energy spectrum ($E(k) \sim k^2$ where E is the energy spectrum and k is the magnitude of the wavenumber vector) at low wavenumbers into the Mann spectral tensor yields a longer streamwise correlation length, resulting in reduced reconstruction error when compared with the Batchelor spectrum ($E(k) \sim k^4$). Finally, we observe that using the HGW model or Mann model with a Saffman spectrum yields similar results.
In recent years, some scientists have called for research into and potential development of ‘solar geoengineering’ technologies as an option to counter global warming. Solar geoengineering refers to a set of speculative techniques to reflect some incoming sunlight back into space, for example, by continuously spraying reflective sulphur aerosols into the stratosphere over several generations. Because of the significant ecological, social, and political risks posed by such technologies, many scholars and civil society organizations have urged governments to take action to prohibit the development and deployment of solar geoengineering techniques. In this article we take such calls for a prohibitory or a non-use regime on solar geoengineering as a starting point to examine existing international law and governance precedents that could guide the development of such a regime. The precedents we examine include international prohibitory and restrictive regimes that impose bans or restrictions on chemical weapons, biological weapons, weather modification technologies, anti-personnel landmines, substances that deplete the ozone layer, trade in hazardous wastes, deep seabed mining, and mining in Antarctica. We also assess emerging norms and soft law in anticipatory governance of novel technologies, such as human cloning and gene editing. While there is no blueprint for a solar geoengineering non-use regime in international law, our analysis points to numerous specific elements on which governments could draw to constrain or impose an outright prohibition on the development of technologies for solar geoengineering, should they opt to do so.
We give an explicit formula to count the number of geometric branches of a curve in positive characteristic using the theory of tight closure. This formula readily shows that the property of having a single geometric branch characterizes F-nilpotent curves. Further, we show that a reduced, local F-nilpotent ring has a single geometric branch; in particular, it is a domain. Finally, we study inequalities of Frobenius test exponents along purely inseparable ring extensions with applications to F-nilpotent affine semigroup rings.
Silicified brachiopods from Hirnantian strata in three sections of the lower Whittaker Formation, Mackenzie Mountains, northwestern Canada, yielded a moderately diverse, Edgewood-type Hirnantian fauna, consisting of 13 species: Biparetis paucirugosus, Brevilamnulella laevis, Dalmanella edgewoodensis, Drabovia noixella, Eospirigerina putilla, Epitomyonia paucitropida, Epitomyonia sekwiensis, Glyptorthis papillosa new species, Gnamptorhynchos orbiculoidea, Katastrophomena mackenzii new species, K. parvicardinis, Parastrophina cf. P. minor, and Skenidioides sp. Compared to the typical Edgewood fauna of the American Midcontinent, Brevilamnulella laevis has a notably smaller shell than B. thebesensis, and is interpreted as a deeper-water form. The strong faunal affinity of the Mackenzie Mountains fauna to the Edgewood-type Hirnantian fauna is indicated by the occurrence of Biparetis, Brevilamnulella, Eospirigerina, and Gnamptorhynchos. In addition to the Edgewood type area within Laurentia, Biparetis, Eospirigerina, and Gnamptorhynchos are characteristic taxa that also occur in the Ellis Bay Formation (Hirnantian) of Anticosti Island. Multivariate and network analyses strongly support the differentiation between an Edgewood-type Hirnantian fauna in Laurentia and peri-Laurentia and the typical Hirnantia fauna of the Kosov Province in Gondwana, peri-Gondwana, South China, Kazakhstan terranes, Avalonia, and Baltica.
Construction Grammar is an emerging theory of language, but the analysis of sociolinguistic variation is still relatively underdeveloped in the framework. In this article, we consider the representation of social meaning in Construction Grammar through a corpus-based analysis of double modals in British English on social media. We describe the use of double modals in a large corpus of geolocated Twitter posts, including presenting an inventory of observed double modals and maps showing the regional distribution of each of these forms. We find that double modals show a general northern pattern and are concentrated in the Scottish Borders. We also find various rare double modals that occur more widely across the UK. To account for these results, we propose a Construction Grammar account of double modals. We argue that defining double modals as grammatical constructions requires that aspects of their social meaning be delimited, especially register and region. Furthermore, we argue that double modals may be enregistered as dialect constructions, distinguished from standard constructions of British English. We conclude by considering the importance of incorporating social meaning into Construction Grammar, underlining the value of a Cognitive Sociolinguistic approach to grammatical theory.
The paper is concerned with positive solutions to problems of the type
\[ -\Delta_{\mathbb{B}^{N}} u - \lambda u = a(x) |u|^{p-1}\;u + f \text{ in }\mathbb{B}^{N}, \quad u \in H^{1}{(\mathbb{B}^{N})}, \]
where $\mathbb {B}^N$ denotes the hyperbolic space, $1< p<2^*-1:=\frac {N+2}{N-2}$, $\;\lambda < \frac {(N-1)^2}{4}$, and $f \in H^{-1}(\mathbb {B}^{N})$ ($f \not \equiv 0$) is a non-negative functional. The potential $a\in L^\infty (\mathbb {B}^N)$ is assumed to be strictly positive, such that $\lim _{d(x, 0) \rightarrow \infty } a(x) \rightarrow 1,$ where $d(x,\, 0)$ denotes the geodesic distance. First, the existence of three positive solutions is proved under the assumption that $a(x) \leq 1$. Then the case $a(x) \geq 1$ is considered, and the existence of two positive solutions is proved. In both cases, it is assumed that $\mu ( \{ x : a(x) \neq 1\}) > 0.$ Subsequently, we establish the existence of two positive solutions for $a(x) \equiv 1$ and prove asymptotic estimates for positive solutions using barrier-type arguments. The proofs for existence combine variational arguments, key energy estimates involving hyperbolic bubbles.
At the Intertropical Convergence Zone (ITCZ), the northern and southern Tradewinds converge, and this region is characterized by low atmospheric pressure and high precipitation. The climate in the Timor Sea is characterized by seasonal precipitation changes driven by meridional migrations of the ITCZ and the monsoonal front. The ITCZ shifts in response to changes in the thermal balance between the northern and southern hemispheres. Thus, reconstruction of paleo-precipitation in the Timor Sea is expected to reveal past changes in both regional and global climate, the latter through inference of the ITCZ position. To reconstruct paleo-precipitation in the Timor Sea, we performed extensive radiocarbon analysis on both planktonic foraminifera and total organic carbon (TOC), which is derived from terrestrial and marine sources. Increased precipitation enhances the fraction of relatively old, terrestrial carbon to the core site, which in turn increases the difference between the ages of TOC and planktonic foraminifera. Variations in radiocarbon ages reveal that during northern hemisphere cooling intervals such as Heinrich Stadial 1 and the Younger Dryas, the ITCZ was in a southern position, thus increasing precipitation in the Timor Sea. However, the Timor Sea was dryer during the Bølling–Allerød warming as the ITCZ shifted northward.