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Traumatic spinal cord injuries (tSCI) are common, often leaving patients irreparably debilitated. Therefore, novel strategies such as nerve transfers (NT) are needed for mitigating secondary SCI damage and improving function. Although different tSCI NT options exist, little is known about the epidemiological and injury-related aspects of this patient population. Here, we report such characteristics to better identify and understand the number and types of tSCI individuals who may benefit from NTs.
Materials and Methods:
Two peripheral nerve experts independently evaluated all adult tSCI individuals < 80 years old admitted with cervical tSCI (C1–T1) between 2005 and 2019 with documented tSCI severity using the ASIA Impairment Scale for suitability for NT (nerve donor with MRC strength ≥ 4/5 and recipient ≤ 2/5). Demographic, traumatic injury, and neurological injury variables were collected and analyzed.
Results:
A total of 709 tSCI individuals were identified with 224 (32%) who met the selection criteria for participation based on their tSCI level (C1–T1). Of these, 108 (15% of all tSCIs and 48% of all cervical tSCIs) were deemed to be appropriate NT candidates. Due to recovery, 6 NT candidates initially deem appropriate no longer qualified by their last follow-up. Conversely, 19 individuals not initially considered appropriate then become eligible by their last follow-up.
Conclusion:
We found that a large proportion of individuals with cervical tSCI could potentially benefit from NTs. To our knowledge, this is the first study to detail the number of tSCI individuals that may qualify for NT from a large prospective database.
Coupling of clearance joint and harsh aerodynamic heating environment is an inevitable nonlinear factor in folding mechanism of the fin of high-speed aircrafts that remarkably modifies natural frequencies and modes of vibration from the initial design state. However, accurately predicting dynamic properties of deployable fin with full consideration of these effects is not common industry practice. A practical semi-analytical model based on Hertz contact theory and ESDU-78035 model is proposed in this study to investigate high-temperature connection stiffness of local hinged–locked mechanisms. Material property degradation and clearance variation caused by thermal expansion are comprehensively considered and quantified in this model. Vibration characteristics of the assembled deployable fin are then solved using finite element method (FEM). The real-time evolutionary process of thermal mode of the fin is discussed. And natural frequencies of fixed-value and time-varying connection stiffness are compared. The simulation results of this study demonstrate that the relative error of structure temperature between the sequential approach and fully coupled simulations is less than 6.98%. The connection stiffness (slope of the load-displacement curve) of the folding mechanism under high temperature conditions decreases by 3.52%, and the variation is mainly caused by the degradation of the elastic modulus of the material, while the clearance change due to the thermal expansion has no significant effect on the slope. The natural frequency of the deployable fin exhibits an inverse correlation with the temperature change trend, and the first three frequencies decrease by 1.67, 7.75, and 16.28 Hz compared to the initial value, respectively.
Some experiments from the history of physics became so famous that they not only made it into the textbook canon but were transformed into lecture demonstration performances and student laboratory activities in the nineteenth and twentieth centuries. While, at first glance, some of these demonstrations as well as the related instruments do resemble their historical ancestors, a closer examination reveals significant differences both in the instruments themselves and in the practices and meanings associated with them. In this paper, I analyse the relation between the research instruments and the respective teaching demonstrations. In doing so, I particularly distinguish between demonstrations that address the process of the actual experimental procedures, and those that focus on the outcome or results (the product) of the experiment. This distinction will be illustrated in some exemplary case studies from the late nineteenth century and the early twentieth in which both the historical experiment and the related educational devices are analysed. The tension between the historical experiment on the one hand, and the different variants of the teaching version on the other, result in the educational as well as epistemological problems that are discussed in this paper.
We feature results on global survival and extinction of an infection in a multi-layer network of mobile agents. Expanding on a model first presented in Cali et al. (2022), we consider an urban environment, represented by line segments in the plane, in which agents move according to a random waypoint model based on a Poisson point process. Whenever two agents are at sufficiently close proximity for a sufficiently long time the infection can be transmitted and then propagates into the system according to the same rule starting from a typical device. Inspired by wireless network architectures, the network is additionally equipped with a second class of agents able to transmit a patch to neighboring infected agents that in turn can further distribute the patch, leading to chase–escape dynamics. We give conditions for parameter configurations that guarantee existence and absence of global survival as well as an in-and-out of the survival regime, depending on the speed of the devices. We also provide complementary results for the setting in which the chase–escape dynamics is defined as an independent process on the connectivity graph. The proofs mainly rest on percolation arguments via discretization and multiscale analysis.
This article explores the formation of a “showmen's culture” among circus employees in the late nineteenth century and the early twentieth, a cultural identity which had the effect of diffusing labor conflicts in this developing industry. The showmen's culture created an affective bond between employees of all levels, from manual laborers, to middle managers, to company owners. This article links cultural history and labor history and provides an example of how workers outside traditional manual-labor industries coped with the challenges of industrialization, and how proprietors used the same cultural identity to their own advantage.
Much business ethics and corporate social responsibility literature suggests, implicitly or explicitly, that firms ought to engage in activities that can be characterized as philanthropy, namely, expending resources beyond what is required by law and market norms to promote others’ welfare at the expense of firm profits. However, this literature has struggled to provide a normative framework for evaluating corporate philanthropy, although scholars have noted that such expenditures can potentially remedy market failures and provide public goods more efficiently. I articulate two specific rationales that can justify corporate philanthropy based on considerations of welfare economics: 1) firms making strategic but high-risk investments in activities that are likely to generate positive externalities even if they prove unprofitable and 2) firms possessing a strong comparative advantage in their ability to address a social problem at lower social cost. Moreover, these rationales can be evaluated by a concept I develop called the philanthropy multiplier, indicating the ratio of net positive externalities to net costs. I suggest that firms consider publicizing their philanthropy multipliers, and I discuss theoretical and practical implications.
This article focuses on the most relevant far right parties since the restoration of democracy in Spain, namely, Fuerza Nueva and VOX. These two parties show divergent electoral trajectories. While the former had some ephemeral prominence during the democratic process of transition, the latter emerged in 2018 and, for the time being, seems to have become established in several political arenas. Through an in-depth qualitative examination, this research explores the role of the organizational institutionalization process in the divergent electoral sustainability of both parties. The results show that it is possible to identify a temporal link, as well as certain mechanisms, between the way in which the parties develop organizationally and their electoral sustainability. In other words, a solid organizational institutionalization process has a positive effect on electoral sustainability. Overall, these findings suggest the need to further strengthen the so-called “internalist perspective” in the agenda of the far right, which entails a more systematic view of the characteristics of the parties themselves to explain their performance.
This article aims to explain the considerable state ownership in listed companies in Norway (SOiN) at present. The extant literature has pointed to alleged national idiosyncrasies to explain this special feature of Norwegian capitalism. The main contribution of this article is a comparative perspective. It shows that most European countries have pursued selective protectionism (i.e., to secure national ownership in key companies). It also shows that financial capital was not crucial for selective protectionism. On this background, the article discusses why state ownership became the mode of selective protectionism in Norway. It argues that the main reason is that large private (often multinational) companies did not develop in the wake of the second Industrial Revolution. Another key reason is that a specific hybrid ownership model that was developed after 1945 became an available institutional solution for securing national ownership after 1990. A common ground and a compromise were found on this model, based both on trust and distrust toward the state: a trust in that the state could operate as a passive and private owner, and a corresponding distrust in the state as an active industrialist and owner.
Aphids exhibit seasonally alternating asexual and sexual reproductive modes. Different morphs are produced throughout the life cycle. To evaluate morph-specific fitness during reproductive switching, holocyclic Sitobion avenae were induced continuously under short light conditions, and development and reproduction were compared in each morph. Seven morphs, including apterous and alate virginoparae, apterous and alate sexuparae, oviparae, males, and fundatrices, were produced during the life cycle. The greatest proportions of sexuparae, oviparae, males, and virginoparae were in the G1, G2, G3, and G4 generations, respectively. Regardless of asexual or sexual morphs, alate morphs exhibited a marked delay in age at maturity compared with that of apterous morphs. Among the alate morphs, males had the longest age at maturity, followed by sexuparae and virginoparae. Among the apterous morphs, sexuparae were older at maturity than the fundatrices, virginoparae, and oviparae. The nymphs of each morph had equal survival potentials. For the same wing morphs, apterous sexuparae and oviparae exhibited substantial delays in the pre-reproductive period and considerable reductions in fecundity, compared with those of apterous virginoparae and fundatrices, whereas alate sexuparae and alate virginoparae had similar fecundity. The seven morphs exhibited Deevey I survivorship throughout the life cycle. These results suggest that sexual production, particularly in males, has short-term development and reproduction costs. The coexistence of sexual and asexual morphs in sexuparae offspring may be regarded as an adaptive strategy for limiting the risk of low fitness in winter.
A new member of the epidote supergroup, ferriandrosite-(Ce), ideally MnCeFe3+AlMn2+(Si2O7)(SiO4)O(OH), was found at the Július manganese ore occurrence near Betliar, Rožňava Co., Košice Region, Slovakia. It occurs as subhedral grains and polycrystalline aggregates, up to 0.3 mm in size, enclosed in pyroxmangite. Other associated minerals are spessartine, rhodochrosite, quartz, baryte and pyrosmalite-(Mn). Ferriandrosite-(Ce) is dark brown, with a light brown streak and vitreous lustre. The Mohs hardness is ~6½ to 7 and tenacity is brittle with no observable cleavage or fracture. The calculated density is 4.321 g⋅cm–3. Ferriandrosite-(Ce) is optically biaxial (+), with weak pleochroism, high surface relief and the mean calculated refractive index is 1.832. The empirical structural formula of ferriandrosite-(Ce), based on 13 anions per formula unit, is A1(Mn2+0.63Ca0.35Ce0.02)Σ1.00A2(Ce0.53La0.27Nd0.14Pr0.05REE*0.01)Σ1.00M1(Fe3+0.41Al0.12V3+0.01Mg0.40Ti0.05)Σ0.99M2Al1.00M3(Mn2+0.75Fe2+0.22Mg0.03)Σ1.00T1–3Si3.00O11O4(O0.67F0.33)(OH), where REE* are minor rare earth elements. Ferriandrosite-(Ce) is monoclinic, space group P21/m, a = 8.8483(4) Å, b = 5.7307(3) Å c = 10.0314(5) Å, β = 113.3659(15)°, V = 466.95(4) Å3 and Z = 2. The crystal structure of ferriandrosite-(Ce) was refined to a final R1 = 0.0210 for 1910 reflections with Fo > 4σ(Fo) and 127 refined parameters. Structural features of ferriandrosite-(Ce) are discussed and compared with other members of the androsite-series.
Using a large sample of leveraged loans, we provide evidence that, despite having fewer creditor control rights, covenant-lite (Cov-Lite) loans have similar recovery rates and significantly lower spreads than loans with maintenance covenants. We find that the propensity to borrow Cov-Lite is related to various proxies for the reputational capital of a borrowing firm’s private equity sponsor. We construct a simple model to illustrate the relationship between reputational capital, covenants, and loan spreads in the leveraged loan market. Our model illustrates how reputational capital can substitute for covenants in mitigating agency costs of debt, leading to lower loan spreads for Cov-Lite loans.
In the context of an ageing population and longer working lives, the impact of increasing rates of early exit from the labour force on quality of life is a particularly current concern. However, relatively little is known about the impact on quality of life of later-life labour force transitions and various forms of early exit from the labour force, compared to remaining in employment. This paper examines lifecourse labour force trajectories and transitions in relation to change in quality of life prior to the State Pension Age. Lifecourse data on early life circumstances, labour force trajectories and labour force transitions from 3,894 women and 3,528 men in the National Child Development Study (1958 British Birth Cohort) were examined in relation to change in quality of life, measured by a short-form version of CASP, between the ages of 50 and 55. Women and men differed in the types of labour force transition associated with positive change in quality of life, with men more frequent beneficiaries. For both men and women, labour force exit due to being sick or disabled was associated with a negative change in quality of life, whereas joining the labour force was associated with a positive change in quality of life. Moving into retirement was associated with a positive change in men's quality of life, but not women's. Moving from full-time to part-time employment was associated with a positive change in women's quality of life but not men's. The findings that stand out for their policy relevance are: the threat to the quality of life of both women and men from early labour force exit due to limiting longstanding illness; and women are less likely to experience beneficial labour force exit in the later years of their working life, but are more likely to benefit from a reduction in working hours.
In direct numerical simulations (DNS) of turbulent Couette flow, the observation has been made that the long streamwise rolls increase in length with the Reynolds number (Lee & Moser, J. Fluid Mech., vol. 842, 2018, pp. 128–145). To understand this, we employ both linear stability theory and its extension to resolvent analysis. For this, we emphasise the high Reynolds number ($Re \rightarrow \infty$) and small streamwise wavenumbers ($\alpha \rightarrow 0$) limit, imposing the distinguished limit $Re_{\alpha }=Re \, \alpha = O(1)$. We find that in case of linear stability theory, $Re_{\alpha }$ acts as a global invariant in the resulting eigenvalue problem, while in case of resolvent analysis, $Re_{\alpha }$ acts as a local invariant in the behaviour of the energy of the system characterised through the first singular value $\sigma _1$ of the resolvent operator within the investigated asymptotic limit. In order to obtain constant streamwise structures for increasing Reynolds numbers, the respective streamwise wavenumber has to decrease, which verifies the observations from DNS studies of an increasing length of the streamwise structures with the Reynolds number. In linear stability theory, a parameter reduction is achieved for the above asymptotic limit, resulting in the modified Orr–Sommerfeld and Squire equations being dependent only on $Re_{\alpha }$. The behaviour of both the coherent structures obtained from linear stability theory and resolvent analysis are compared with each other and show similar behaviours over $Re_{\alpha }$.
The three years that I spent at Royal Holloway, University of London between 1975 and 1978, as professor and head of the History Department, were among the happiest and most purposive of my entire academic life. This was due, in no small part, to my instant friendship with Francis Robinson. We soon realised that our interests converged to a remarkable degree, despite the gulf of almost two millennia between my own concern for the world of Late Antiquity and his with religion and politics in contemporary India and Pakistan.