We construct the first examples of infinite sharply 2-transitive groups which are finitely generated. Moreover, we construct such a group that has Kazhdan property (T), is simple, has exactly four conjugacy classes and we show that this number is as small as possible.

This research communication screened and identified differentiated expressed genes in bovine mammary epithelial cells (BMECs) upon prolactin (PRL) stimulation. PRL of 5 μg/ml increased β-casein synthesis in BMECs with milk protein synthesis capacity. RNA sequencing (RNA-seq) was used to screen differentially expressed genes (DEGs). A total of 375 DEGs (165 up-regulated and 210 down-regulated) were identified between PRL-stimulated group and the control group. Gene ontology enrichment analysis showed that the up-regulated genes were primarily associated with cell functions, metabolic processes, and biological regulatory processes. Pathway enrichment analysis showed that the up-regulated genes were mainly enriched in JAK-STAT, Rap1, Ras and Notch signaling pathways, which are widely involved in cell proliferation, differentiation and milk component synthesis. This study provides an initial understanding of the changes in gene expression in BMECs with PRL-stimulation, as determined by RNA-seq transcriptomic analysis, thereby enhancing our knowledge of the molecular regulation of lactation metabolism.

For young men in Cameroon, football has long been a paradigm of sociality through competitive spirit. In recent decades, however, the stakes of competitive football have been raised: the sport has also emerged as a strategy for young men to migrate abroad and earn a living. On and off the football fields, young men seek to grab limited opportunities to sign contracts with clubs abroad, but few succeed. However, the aspiring athletes rarely see themselves as autonomous individuals competing for a limited number of spots in football clubs. Rather, they attribute failure or success to questions of trust and mistrust: in competitive peers, in neighbours and kin, in Pentecostal Christianity, and in football as a source of livelihood. Competing for a place in a global football industry has led the footballers to mistrust potentially envious others, but also increasingly to put their faith in a Christian God and develop a confident orientation towards a future of success despite the odds. The nexus of football, religion and migration aspirations in Anglophone Cameroon reveals how trust retains a central, albeit ambiguous, place in high-stakes competitive environments, namely as a leap of faith and a confidence in engaging uncertainty. It complicates the idea of competition as a singular and neutral principle that obviates the need for trust, and refines anthropological theory that tacitly confines trust to interpersonal relationships.

Using the concept of the carceral state, this article articulates how Israel’s control of the West Bank and the Gaza Strip has shifted to a nondemocratic one-state paradigm. While, initially, Israel operated a separate military carceral system for these areas, between 2000 and 2006 it dismantled the military system, transferred most Palestinian prisoners into Israel, and rebranded its civilian prison service as the National Prison Authority, making it the sole agency responsible for the incarceration of Palestinians. This reorganization consolidated a single carceral system inside Israeli territory—the one carceral state— which serves as crucial evidence of the de facto one-state paradigm and forms a centerpiece of this new regime in Israel/Palestine. By analyzing a broad range of archival and administrative documents and 168 Supreme Court decisions on the management of prisons and Palestinian prisoners, this study reveals how the massive “exclusionary inclusion” of the Palestinian prisoner population in Israeli state law and its administrative mechanisms changes the entire landscape of the Israeli settler-colonial citizenship regime. Palestinian prisoners become “carceral citizens” of the “one state” and are subject to a parallel, alternate legality, in which they expand their repertoire of resistance against the wider racialized and repressive regime across Palestine/Israel.

The international struggle against impunity for perpetrators of atrocities, including genocide, crimes against humanity, and war crimes, has been a key interest of the international community since the end of World War II. Many achievements have been accomplished with respect to international collaboration on the “substantive issues” of international criminal law (ICL), such as defining and criminalizing the core crimes of international law, yet collaboration on the procedural and practical aspects of ICL, known as mutual legal assistance (MLA) has been neglected.

The aim of this study was to evaluate parameters for the prediction of peripartum hypocalcemia in cattle. The study consisted of two independent investigations (A and B) conducted in different time periods and locations. Blood sera were analyzed for the activity of alkaline phosphatase (ALP), the concentration of ionized (iCa), and total calcium (Ca) two weeks before calving. On the day of calving, urinary net acid/base excretion was calculated, and the serum Ca concentration was analyzed. Ca concentration less than 2 mmol/l on the day of calving was defined as hypocalcemia. The results differed between the two investigations. Part A showed high predictive values for the antepartum parameters ALP and Ca concentration, but these could not be replicated in part B. Animals enrolled were quite young (average age 5.5 years) and the group of animals with hypocalcemia was comparably small in both investigations. The reason(s) for the different results in investigation A and B are not clear. These findings indicate that there are probably as yet unidentified parameters and influences on calcium homeostasis in cattle. None of the parameters investigated in the present study can be considered a reliable universal parameter for prediction of hypocalcemia risk in general.

This article assesses the inner workings of Cuban diaspora statecraft behind the ‘La Nación y la Emigración’ Conference, post-Soviet era Cuba's first major outreach to the Cuban community abroad. In contrast to works observing how changing emigration demographics might have transformed Cuba, this study argues that the Cuban state purposefully tried to reshape the homeland–diaspora relationship through the design of its emigration strategies. Because the Cuban geopolitics of mobility had profound security, economic and ideological implications, the leadership discussed not just how to neutralise the counterrevolution abroad but how to address both the diaspora's needs and popular sentiment at home.

The morphology of female bopyrids is adapted to parasitism, but understanding the function of their thoracic and mouth appendages is hindered by their small size and cryptic lifestyle, limiting detailed examination. This study aimed to clarify the function of the first oostegites and maxillipeds in bopyrid isopods infesting the branchial chamber of caridean shrimp through behavioural observations and morphological examination. We tested whether the movement of these structures was exclusive to ovigerous female parasites during brood ventilation. The results revealed that the beating of the maxillipeds and flapping of the first oostegites were not restricted to ovigerous females. However, the frequency of these movements was significantly higher in ovigerous females than in non-ovigerous females. The frequency of maxilliped beating increased with embryonic development, whereas that of flapping the first oostegites exhibited the opposite trend. Microscopic observation using dye showed that the movements of the maxillipeds and the first oostegites expelled residual dye from the female brood chamber through the dorsal surface or beneath the first oostegites. The dye was then transported by the water current generated by the scaphognathite of the host shrimp. These findings suggest that these structures not only facilitate ventilation but also serve as a grooming mechanism for female parasites, which is critical for embryonic survival. The results of the present study represent the first observation of embryo grooming in bopyrid isopods. This study also provides new information on the functional morphology of bopyrid isopods, which is important for understanding their ecological dynamics and adaptation to parasitism.

This article progresses Second World War historiography of ‘enemy alien’ internment, especially of the SS Arandora Star, sunk in 1940 with a high loss of Italian civilian lives. Employing a new paradigm, that of the deathscape, defined as a topography of death and the practices that surround it, this investigation recontextualises Arandora Star remembrance in Scotland. Ambiguous loss, complicated grieving, disenfranchisements in mourning and absences in multiple layers of the deathscape form overarching themes that are explored in parallel to emotional-affective memory. The previously neglected study of individual memorialisation, both private and ‘official’, provides an important primary source in the fragmented materiality of the deathscape, allowing fresh insight on both cultural manifestations and political context. As the material and cultural apex of the deathscape, the Italian Cloister Garden and Arandora Star Memorial in Glasgow, created by Archbishop Mario Conti in 2011, are evaluated through the lenses of leadership, identity and heritage activism.

The aim of this research was to investigate the ability of an in vitro simulated gastrointestinal digestion (SGID) to generate peptides from bovine lactoferrin (LF) that possess antibacterial activity. Escherichia coli was examined as the target pathogen due to its prevalence in foods and the well-documented antibacterial effect of both LF and LF peptides against this organism. Results showed that in-vitro digested LF, specifically gastric LF digesta, exhibited significant antibacterial activity at low concentrations against E. coli compared to its undigested counterpart. Additionally, the highest antibacterial activity in the gastric digesta was associated with a relatively high molecular weight fraction of >30 kDa obtained within the first 30 min of the SGID. This demonstrates that the digestive process can result in the generation of antibacterial LF peptides and contribute to improving the antimicrobial properties of LF exhibited in its undigested state, making it a suitable dairy food additive to potentially provide protection against bacterial pathogens within the gastrointestinal system.