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This ethnography explores the temporalizing practices of workers at the Litani River powerplant—a key site of national infrastructural development in Lebanon. Departing from dominant narratives of crisis or collapse, it argues that workers inhabit a distinct spatial and temporal mode described as tarabuṭ maṣlaḥi, an ambivalent alliance of convenience with the Litani river, its infrastructure, and the state. Rather than viewing their experience through paradigms of progress or decline, workers cultivate a modular relation to time, and to the seemingly isolated powerplant, marked by endurance. Tarabuṭ maṣlaḥi, the article suggests, is a mode of exercising and reproducing power at the intersection of material structures and embodied experience. Like a Möbius strip, its fraught political relations and dynamics of social reproduction continuously weave the space they constitute. It illustrates power’s reach through time while also revealing workers’ subtle ways of challenging it, beyond binaries of submission or resistance.
Familial hypercholesterolaemia remains substantially underdiagnosed worldwide despite effective preventive therapies. Evidence increasingly supports paediatric-centred detection combined with cascade and reverse cascade strategies to improve population-level identification and reduce premature atherosclerotic cardiovascular disease. We summarise contemporary familial hypercholesterolaemia screening models with emphasis on paediatric approaches, implementation barriers, and health system requirements, and we present the EPIRUS Familial Hypercholesterolaemia Reverse Cascade Project as a pragmatic regional model in Greece. A literature search (December 2025 to January 2026) was performed in PubMed, Scopus, and Google Scholar using terms related to “familial hypercholesterolemia,” “familial hypercholesterolaemia,” “screening,” “cascade,” “reverse cascade,” and “population programme.” Eligible publications included human studies and evidence syntheses evaluating universal, opportunistic, cascade, or paediatric screening strategies, and implementation or economic analyses. Evidence consistently indicates that opportunistic detection and conventional cascade screening alone cannot close the diagnostic gap because of low index-case ascertainment and fragmented pathways. Universal or structured paediatric programmes demonstrate feasibility, high diagnostic yield after infancy, and capacity to trigger family-based case-finding. Recent data show low-density lipoprotein cholesterol discrimination is limited in newborns but becomes reliable from age ≥1 year, supporting childhood screening. We describe EPIRUS Familial Hypercholesterolaemia, a targeted paediatric programme (primarily ages 4–16 years) using lipid thresholds and family history triggers, systematic phenotyping, and next-generation sequencing to confirm diagnosis and enable cascade and reverse cascade screening. EPIRUS Familial Hypercholesterolaemia illustrates how paediatric entry points can operationalise family-based detection within routine clinical care in a decentralised setting and can generate real-world implementation evidence to inform scalable national strategies.
This contribution presents the analysis of previously undescribed material from Early Jurassic deposits of west-central Argentina. Opisoma is an astartid bivalve assigned to the subfamily Opinae. It is characterized by its robust trigonal hinge and the absence of lateral teeth. Wing-shaped bivalves are an informal, polyphyletic group characterized by shells strongly compressed in the anteroposterior direction, a case of morphological convergence that appears in several extinct lineages, including Opisoma, and persists today in the cockle Corculum. Although astartids typically show shallow infaunal habits, Opisoma developed an epifaunal or semi-infaunal lifestyle, maintaining the commissural plane perpendicular to the substrate, likely associated with photosymbiosis. During the Early Jurassic, reef systems developed in low-latitude marine environments of the Tethys and Panthalassa, dominated by large gregarious bivalves known as the Lithiotis fauna, within which Opisoma represented a subordinate component. The specimens studied here were analyzed using traditional techniques and computed tomography to provide new, robust evidence addressing the longstanding debate regarding valve orientation in Opisoma. The new species Opisoma romeroi is described. This Neuquén Basin record represents the southernmost occurrence known for the genus and significantly expands its paleogeographic distribution.
This paper offers a reassessment of the expansion of Spanish banks in Latin America between 1990 and 2020. We build upon the seminal work of Pablo Martín-Aceña and draw on the intangible assets framework developed by Guillén (2005) and Guillén & García Canal (2010). Incorporating new primary sources, particularly first-hand testimonies from key participants, we argue that it was not financial strength or technological invention that necessitated expansion, but decisive organizational capabilities proved instrumental. This perspective sheds new light on the motivations behind the expansion, the processes of consolidation, and the relative success of Spanish banks in the region. Our analysis reveals how strategic entry methods, innovative managerial practices, and targeted technological developments enabled these institutions to gain a competitive edge over both domestic banks and long-established international competitors. A key theoretical contribution lies in our distinction between technological adoption and transformative deployment.
Let $(A,G,\alpha )$ be a partial dynamical system and let $A\rtimes _{\alpha ,r} G$ denote the associated reduced partial crossed product. We introduce the Haagerup property for partial actions of discrete groups on $C^*$-algebras. We prove that the partial crossed product $A\rtimes _{\alpha ,r} G$ has the Haagerup property if and only if both A and the partial action $\alpha $ have the Haagerup property. As a consequence, we obtain an equivalence between the Haagerup property of the partial crossed product, and that of the underlying $C^*$-algebra and the acting group. We also show that the Haagerup property is preserved under inductive limits of $C^*$-algebras and apply this result to study the Haagerup property of inductive limits of partial crossed products.
Let $F \ast G$ be a free product of a free group F and a LERF group G. We provide sufficient conditions for a subgroup H of $F \ast G$ to be $\mathcal A\cup \mathcal S$-separable, that is, for any finite set $\{\gamma _1, \ldots , \gamma _n\} \subset (F \ast G) \setminus H$, there is a surjection f from $F \ast G$ to an alternating or symmetric group such that $f(\gamma _i) \notin f(H)$ for all i. As a corollary, any finitely generated infinite-index subgroup of a free group is $\mathcal A\cup \mathcal S$-separable in the free product of the free group and an arbitrary LERF group, generalising a result of Wilton [‘Alternating quotients of free groups’, Enseign. Math.58 (2012), 49–60].
Glucagon-like-peptide-1 (GLP-1) agonists are beneficial for glycaemic control, weight loss, and cardiovascular health. Because GLP-1 agonists may be a useful tool in the management of obesity in patients with congenital heart disease (CHD), we examined whether GLP-1 agonists are effective and safe for weight loss in adults with congenital heart disease (ACHD) and explored the effects of sex and CHD complexity.
Methods:
We conducted a retrospective cohort study of ACHD patients who were prescribed a GLP-1 agonist from 1/1/2022–3/31/2024 at Yale New Haven Hospital. Patients were subdivided by CHD anatomic complexity. The primary outcome was the change in weight over time. Side effects were explored as a secondary outcome.
Results:
The moderate complexity ACHD group had the fastest weight loss during both the first 6 months and 12 months of treatment, but was comparable to the other two ACHD complexities in the full period of follow-up. Patients in the simple and great complexity groups required 12 months of treatment to reach meaningful weight loss. Females had a faster rate of weight loss compared to males across all ACHD complexity levels. The most common side effects reported were gastrointestinal, such as nausea, acid reflux, and diarrhoea.
Conclusion:
This study provides evidence that GLP-1 agonists are effective for weight loss in ACHD patients, with the greatest weight loss in females and patients with moderate ACHD complexity. Moreover, GLP-1 agonists in the ACHD population have a reasonable side effect profile that is typical for these agents.
Douglas Laycock’s career in Religion Clause scholarship and advocacy spans two periods marked by two distinct concerns at the heart of the debates. This article connects them. In the first period, from the 1980s into the 2000s, the central issue was what general value or principle should drive Religion Clause decision-making. Laycock’s approach, substantive neutrality toward religion, focused on minimizing government effects on religious choices and thus led the way in reconciling two key values: neutrality on the one hand, and religious liberty or voluntarism on the other. In the second period, from the mid-2000s forward, religious liberty became caught up in the United States’ cycle of polarization. Laycock again led the way; his work on Religion Clause neutrality supports the effective defense of religious liberty in a polarized age. In particular, he called for aggregating neutrality: recognizing that any policy can have differing effects on the religious choices of different relevant actors and comparing those effects with the goal of minimizing burdensome effects on religious choices overall. This approach, done with care, can take account of the effect on competing sides and thus productively address polarized conflicts.
Racial and ethnic disparities in Clostridioides difficile infection outcomes have been reported but are incompletely understood. In a retrospective study at a major academic hospital, we observed that testing rates were lower in racially and ethnically minoritized (REM) patients, but important outcomes did not differ.
Word Grammar (WG), a dependency grammar, has historically permitted mutual dependency, a structure where two words depend on each other. This paper re-evaluates mutual dependency within WG, focusing on contradictions arising when dependency relations are inherently tied to word-order via WG’s ‘landmark’ relation. It is argued that mutual dependency which involves conflicting landmark relations is untenable. I examine earlier WG analyses of English dependent interrogatives and free relatives, which were the principal motivators for mutual dependency analyses. It is proposed that dependent interrogatives do not require mutual dependency and are better analysed with the verb as the head, with selection being semantic. Free relatives, however, with their matching effects where the wh-word is head, necessitate a form of mutual constraint. A solution is offered by refining WG’s theory of word-order and its relationship to extraction, by distinguishing between the general relationship of word-order, ‘landmark’ and a distinct relation of word-order that is part of the extraction start-rule. This approach allows for mutually constraining relations in free relatives without contradictory landmark assignments, thereby preserving a coherent theory of word-order while accommodating mutual dependency.
Accurate crop growth models are essential for predicting yield and evaluating adaptation potentials under climate change. As one of Europe’s most important forage crops, silage maize (Zea mays L.) requires a model that captures genotype-specific growth traits and environmental variability. The current study presents HUME-Maize (Hannover University Modelling Environment), a new process-based model for silage maize, specifically adapted to conditions in Northern Europe. Model development relied on an extensive dataset from two field trials (2007–2008, 2021–2022) at five sites across Germany, involving two mid-early maize hybrids released 12 years apart. Calibration was based on the older hybrid and evaluated on both, testing the need for hybrid-specific parameter adjustments. Model scalability and predictive accuracy were assessed with a nationwide dataset covering 287 site-year combinations. The baseline model, parameterized using an older hybrid, reproduced biomass formation well (d = 0.98 and 0.95). Application to a newer hybrid without adjustment revealed systematic differences in leaf development and yield formation associated with breeding progress. Hybrid-specific adjustments of physiological traits, e.g. leaf growth rate, specific leaf area and radiation use efficiency, substantially improved model performance, reflecting the enhanced radiation use efficiency of the newer hybrid. On the national scale, the model achieved low prediction errors for final yield (16 % for the older and 21 % for the newer hybrid). Drought and nitrogen stress responses remain areas for refinement. HUME-Maize thus provides a robust framework for simulating hybrid-specific silage maize growth, supporting yield prediction and physiological analysis across hybrids and environments.
This study examines clay fragments found at Çemka Höyük, a Pre-Pottery Neolithic site in Mardin, Türkiye (tenth millennium BC). Analysis of mineral inclusions in the clay matrix indicates that these fragments may have been deliberately fired, representing an early example of ceramic technology in South-west Asia. The diversity of forms identified and their likely uses suggest, the authors argue, a formative phase in ceramic innovation during which the properties and potential applications of clay were explored by the local community and adopted and adapted within existing social and economic traditions in advance of widespread application in the seventh millennium BC.
In this paper, we analyze the distribution of the total overlapping time spent with other customers in the $\mathrm{M}_\lambda/\mathrm{M}_\mu/1$ queue with First-Come First-Served service discipline. We show that the Laplace–Stieltjes transform of the overlapping time reduces to an incomplete gamma function representation. We also calculate the transform of the joint distribution of the overlapping time and the number of overlaps. In addition, we prove a heavy-traffic limit for the total overlapping time with scaling $1/(1-\rho)^2$ to a $\operatorname{Weibull}(1/2,1/\mu)$ random variable. Finally, for the $\mathrm{M}_{\lambda}/\mathrm{G}/1$ case, we derive the first two moments of the overlapping time.