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The Ediacaran Subcommission of the International Commission on Stratigraphy is diligently working toward the goal of subdividing the Ediacaran Period into precise and useful chronostratigraphic units. As emphasized by Xiao and colleagues in 2016, one of the most effective tools in this endeavor will be the use of index fossils. Our special issue serves as a presentation of ongoing research efforts aimed at advancing this task and contains explorations into taxonomy, taphonomy, and the diversity of life during the Ediacaran Period.
In many European countries, semi-autonomous agencies have been created in health policy to safeguard general public interests. In executing their tasks, these agencies need to deal with conflicting expectations. Particularly avoiding the risk of regulatory capture and aligning with parent ministries are frequently studied challenges, even more so when complex issues such as scarcity are at stake. In this paper, we use q-methodology to provide a thorough overview of the debate regarding the role of an important agency in the Dutch healthcare system; the National Health Care Institute (Zorginstituut Nederland). We conducted 41 q-interviews with agency employees, evaluators, regulatees, ministry employees, health policy experts, members of its advisory committees, and peer agencies. We identify three viewpoints on what the agency should focus on. These are on societally relevant issues, strict package management, and efficient organisation of care. In doing so, our study shows how agencies are pulled in different directions by conflicting expectations. We show that this can be problematic because it complicates a clear role of the agency that allows addressing such issues. We thereby contribute to theories on agencies' complex relations with their external environment such as regulatory capture, tripartism, reflexive regulation, legal boundaries, and stewardship theory.
Urban co-creation is an approach to urban design that actively involves stakeholders and end-users in the design process. As designers increasingly use digital tools to manage design information, stakeholders and residents may find it difficult to participate, resulting in a lack of engagement. The emergence of metaverse technologies offers a crucial opportunity to employ user-friendly and collaborative tools, enabling more effective participation. In the study presented in this article, a custom-designed digital game with virtual reality environment was used to facilitate a series of co-creation workshops. The study focused on changes in participants’ experience by comparing baseline and endline survey results against the design outputs. It employed a holistic framework considering four dimensions: game design, participatory experience, learning outcomes and co-creation results. The findings indicate that the digitally gamified approach helped enhance participation and knowledge sharing, and even though game design ratings varied, the use of video games motivated engagement, particularly in an intergenerational context. The co-creation workshop design documented in this article offers new methods to enhance community engagement in urban design. Especially during digital transformation, it opens renewed discussions on balancing traditional output-driven approaches with more participant-centric methods and design objectives.
The Republic of Cyprus has recorded the greatest increase in suicide mortality among Eastern Mediterranean countries, with an average annual increase of 5.1% in 2000–2019.
Aims
To investigate trends in suicide mortality rates between 2004 and 2020 in the Republic of Cyprus, with a focus on age, gender and suicide methods.
Method
Suicide deaths (ICD-10 taxonomy, including ‘undetermined’ code) and population denominators were obtained from the National Mortality Registry and Statistical Office, respectively. Directly standardised (European Standard) mortality rates were calculated for four gender and age groups. Annual change was estimated using Poisson regression models with interaction terms to assess differential trends over different time periods.
Results
There were 560 suicide deaths; these were four times more frequent in men, and approximately 80% were classified as ‘violent’ for both genders. The male suicide rate doubled from 4–5 to 9–10 per 100 000, mostly before 2012, representing a 9% annual change (rate ratio = 1.09, 95% CI 1.03, 1.15; P = 0.002). From 2013, the trend reversed (effect modification P < 0.001) with a 4% annual decrease (95% CI −9%, 1%). Declines were not uniform across all age groups; rates in males aged 45–64 years continued to rise, surpassing the previously high rate in males aged 25–44 years. Rates in females declined from 4–5 per 100 000 to 2–3 over the study period. Overall, the male-to-female suicide rate ratio was 5.33 (95% CI 3.46, 8.19) in 2017–2020, compared with 2.73 (1.88, 3.95) in 2004–2008.
Conclusion
Although suicide rates remain relatively low, the gender differential has widened in the Republic of Cyprus. Further analysis of trends in relation to unemployment and other socioeconomic indicators is warranted.
We show that if one of various cycle types occurs in the permutation action of a finite group on the cosets of a given subgroup, then every almost conjugate subgroup is conjugate. As a number theoretic application, corresponding decomposition types of primes effect that a number field is determined by the Dedekind zeta function. As a geometric application, coverings of Riemannian manifolds with certain geodesic lifting behaviours must be isometric.
Poursuite de l’invasion de l’Ukraine, guerre dans la bande de Gaza, crise alimentaire, transition énergétique sans précédent, rééquilibrage géostratégique, montée du populisme, ingérence de toute sorte, explosion du recours à l’intelligence artificielle, inflation à maîtriser, voilà autant de traits caractérisant l’année 2023 et ayant eu le potentiel de redéfinir les relations commerciales mondiales. Dans ce contexte, mu par une nouvelle diplomatie pragmatique,1 le Canada tente d’innover tout en renouant avec son rôle d’antan: préserver ses partenaires usuels tout en développant de nouvelles relations d’opportunité (au risque parfois de piler sur ses valeurs), réinvestir les enceintes internationales avec le dessein de les moderniser, diversifier ses relations en déployant des forces diplomatiques dans de nouveaux territoires et réaffirmer sa souveraineté face à toute sorte de menaces que ce soit en Arctique ou dans le cadre électoral canadien. Ce contexte a nécessairement eu des impacts sur les choix que fait le Canada en matière commerciale.
Anthropogenic climate change is a significant driver of disasters, such as tropical storms, floods, drought and loss of biodiversity, amplifying their frequency and severity worldwide. The annual incidence of extreme weather-related events increases with growing human exposure to risks. The Sendai Framework and its associated Sustainable Development Goals (SDGs) recognise the interlinkages between disaster risk reduction, climate change adaptation and sustainable development. However, despite the best intentions of disaster planners, the current efforts are suboptimal in promoting implementation. Education is a critical goal to achieve sustainable development. Environmental Education for Sustainable Development (ESD) seeks to equip students with the knowledge, skills, values and agency necessary to address the complex challenges of climate change and global warming. One example of such an educational programme is the “Speak to Me in Numbers” programme. This interdisciplinary ESD programme educates 9th graders in SDG-related scientific content through scientific data analysis. It strives to inspire students to develop their agency and become responsible future citizens by taking local climate action to bring about sustainable development in their communities. Empowered young people who become agents that bring about global changes are crucial in the context of the climate crisis. However, such efforts should be undertaken cautiously to avoid doing more harm than good by evoking climate anxiety. These implications are discussed.
To assess associations between self-reported advertising exposure to foods high in fats, salt and sugar and household purchases of energy, nutrients and specific product categories.
Design:
A cross-sectional design was used. Advertising exposure data were gathered using a questionnaire administered to the main shopper of each household, and purchase data from supermarkets and other stores for these households were accessed for a 4-week period during February 2019.
Setting:
Households in London and the North of England.
Participants:
Representative households (N 1289) from the Kantar Fast Moving Consumer Goods Panel. Main shoppers were predominantly female (71 %), with a mean age of 54 years (±13).
Results:
Linear regression models identified that exposure to foods high in fats, salt and sugar advertising through traditional mediums (including broadcast and print), but not digital, transport, recreational or functional mediums, was associated with greater purchases of energy (9779 kcal; 95 % CI 3515, 16 043), protein (416 g; 95 % CI 161, 671), carbohydrate (1164 g; 95 % CI 368, 1886) and sugar (514 g; 95 % CI 187, 841). Generalised linear models showed that individuals who reported exposure to sugary drink advertising were more likely to purchase sugary drinks (1·16; 95 % CI 2·94, 4·99) but did not purchase more energy or nutrients from sugary drinks. There was no evidence of associations between exposure to advertising for sugary cereals or sweet snacks and purchases from these categories.
Conclusions:
There was a strong influence of traditional advertising and sugar-sweetened beverage advertising on household food and drink purchases, thus supporting the need for advertising restrictions across traditional formats and for sugary drinks specifically.
There has long been debate about the capacity of the US Supreme Court to achieve “progressive” social change. Recent decisions of the court also point to a new worry for American progressives: the court may not only have a limited capacity to drive such change. In some cases, it may actively stand in the way of such change or help reverse it. This invites us to rethink when, or under what conditions, courts are likely to be effective in driving change—whether in a positive, dynamic, or else more obstructionist or regressive direction.
To assess the psychosocial functioning concerning obsessive-compulsive symptoms (OCS) and/or obsessive-compulsive disorder (OCD) comorbidity in people with schizophrenia, schizoaffective disorder, or bipolar disorder diagnosed in a large case register database in Southeast London. Data were retrieved from the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) register using Clinical Record Interactive Search (CRIS) system, a platform allowing research on full but de-identified electronic health records for secondary and tertiary mental healthcare services. Information of schizophrenia, schizoaffective disorder, bipolar disorder diagnosis and OCS/OCD status was ascertained from structural or free-text fields through natural language processing (NLP) algorithms based on artificial intelligence techniques during the observation window of January 2007 to December 2016. Associations between comorbid OCS/OCD and recorded Health of the Nation Outcome Scales (HoNOS) for problems with activities of daily living (ADLs), living conditions, occupational and recreational activities, and relationships were estimated by logistic regression with socio-demographic confounders controlled. Of 15,412 subjects diagnosed with schizophrenia, schizoaffective disorder, or bipolar disorder, 2,358 (15.3%) experienced OCS without OCD, and 2,586 (16.8%) had OCD recorded. The presence of OCS/OCD was associated with more problems with relationships (adj.OR = 1.34, 95% CI: 1.25–1.44), ADLs (adj.OR = 1.31, 95%CI: 1.22–1.41), and living conditions (adj.OR = 1.31, 95% CI: 1.22–1.41). Sensitivity analysis revealed similar outcomes. Comorbid OCS/OCD was associated with poorer psychosocial functioning in people with schizophrenia, schizoaffective disorder, or bipolar disorder. This finding highlights the importance of identification and treatment of comorbid OCS among this vulnerable patient group.
Cell and gene therapies derive from a substantial manipulation of cells or the application of gene editing techniques. They are promising products because they enable therapy personalisation, are potentially helpful for treating rare or resistant diseases, and may become useful in future epidemics. Because of this strategic worth, the infrastructure needed for manufacturing these therapies is turning into a subdomain within the domain of critical infrastructures (CIs), understood as the structures whose operation is key for the integrity and security of a nation. This paper analyses why cell and gene therapy infrastructure can be considered as an emergent CI domain, stressing three aspects: automated manufacturing equipment; software solutions (including the growing adoption of artificial intelligence and cloud technology); and human expertise. These complex manufacturing systems, which are becoming increasingly automated and digitalised, may be surrounded by new risks and vulnerability points, which requires adequate regulatory solutions and governance initiatives. A comprehensive approach is therefore advanced here, where therapy manufacture has medical and technological relevance, but is equally crucial from the viewpoint of nations’ public health and internal stability.
The electroosmotic flow (EOF) fields in the vicinity of solids with high dielectric permittivity are studied for the case of charge-asymmetric electrolyte solutions. Corresponding solutions of the coupled Poisson–Nernst–Planck and Navier–Stokes equations are obtained analytically and numerically. When a direct-current (DC) electric field is applied to a high-permittivity uncharged sphere, a net EOF develops that translates into a non-zero electrophoretic mobility of the sphere, although it does not carry any charge. Similarly, a DC field acting on a channel in a high-permittivity material results in a net flow through the channel, although the solid is uncharged. Such phenomena are expected to occur frequently whenever high-permittivity solids are immersed in charge-asymmetric electrolyte solutions and do not rely on special scenarios such as ion crowding. Also, the net flow velocities are very significant for realistic values of the electric field strength. The derived scaling relationships even predict giant net flow velocities through nanochannels of the order of metres per second for practically relevant scenarios.
It is a revealing exercise to search for variations of the word “colonial” in the indexes and tables of contents of these recent monographs in Anglophone literary studies. As the subdiscipline begins to chronicle contemporary cultural developments in which the British Empire’s legacies grow ever-less marked, it is perhaps inevitable that the terms and concepts that governed the preceding phase of scholarship—colonialism, imperialism, and postcolonialism—begin to recede into the background. The sudden and sharp recession of these terms, however, raises fundamental questions regarding the study of English-language texts from the Caribbean, South Asia, West, and East Africa (among other locales). Among the foremost of such questions may be: does the term “postcolonialism” now designate a mere literary period, as opposed to being what scholars over the last several decades seem to have agreed it also is, namely a critical method? What are the effects and implications of this shift, wherein not just literary works newly arrived to a world scene still marked and structured by colonial legacies, but older ones long identified as definitionally “postcolonial,” are increasingly treated without such concepts and terms? Suggestions of answers to such questions arise throughout these three books, all of which seek to reconsider one of the keystone concerns of postcolonial studies, namely the relationship between contemporary Anglophone writing and the authors and texts of the British literary canon.
For given positive integers $r\ge 3$, $n$ and $e\le \binom{n}{2}$, the famous Erdős–Rademacher problem asks for the minimum number of $r$-cliques in a graph with $n$ vertices and $e$ edges. A conjecture of Lovász and Simonovits from the 1970s states that, for every $r\ge 3$, if $n$ is sufficiently large then, for every $e\le \binom{n}{2}$, at least one extremal graph can be obtained from a complete partite graph by adding a triangle-free graph into one part.
In this note, we explicitly write the minimum number of $r$-cliques predicted by the above conjecture. Also, we describe what we believe to be the set of extremal graphs for any $r\ge 4$ and all large $n$, amending the previous conjecture of Pikhurko and Razborov.
The ability and knowledge to manage financial tasks may be compromised in old age, especially when the need to navigate the care and social benefit systems increases. Managing financial tasks may consist of a variety of actions of both the older people themselves and their representatives, often family members. This study explored how financial tasks related to the care and everyday life of older people who need long-term care are managed by using the ideas of modalities of agency and distributed agency. We analysed interviews of 19 older persons and their family members with a qualitative case analysis. All the older persons who participated in the study distributed the agency in financial tasks among their family members, but to different levels and for different reasons. We identified three types of distributed agency – inevitable, assimilated and minimal distributed agency – in which the older persons’ knowledge about financial tasks and their ability to manage financial tasks differed. Within these types, the cases differed in terms of the know-how of the family members and the reasons why the older people’s knowledge about financial tasks or their ability to manage their financial tasks were diminished. We conclude that older persons with long-term care needs require help in regard to financial tasks, and the older people’s and their family members’ ability to manage financial tasks could be enhanced by making the benefit systems and online banking more user-friendly and by improving the help from care staff.
The research reconstructs and analyses the role played by livestock associations in Italy during the 20th century. The article initially focuses on local associative experiences before World War II and subsequently on national associations, whose formation also depended on the goal of promoting the application of technical innovations. Their impact, specifically that of artificial insemination and semen freezing, has indeed influenced the production process in the livestock sector since the 1940s with genetic changes in animals for productivity purposes. Focusing on specific case studies (mainly Associazione Italiana Allevatori, but also ANAFI, ANARB, and ANABIC), the paper analyses the motivations behind the establishment of the associations, the relationships with members and public institutions, and finally, support strategies for breeders.
Cooperative behavior constitutes a key aspect of human society and non-human animal systems, but explaining how cooperation evolves represents a major scientific challenge. It is now well established that social network structure plays a central role for the viability of cooperation. However, not much is known about the importance of the positions of cooperators in the networks for the evolution of cooperation. Here, we investigate how the spread of cooperation is affected by correlations between cooperativeness and individual social connectedness (such that cooperators occupy well-connected network positions). Using simulation models, we find that these correlations enhance cooperation in standard scale-free networks but not in standard Poisson networks. In contrast, when degree assortativity is increased such that individuals cluster with others of similar social connectedness, we find that Poisson networks can maintain high levels of cooperation, which can even exceed those of scale-free networks. We show that this is due to dynamics where bridge areas between social clusters act as barriers to the spread of defection. We also find that this positive effect on cooperation is sensitive to the presence of Trojan horses (defectors placed within cooperator clusters), which allow defection to invade. The results provide new knowledge about the conditions under which cooperation may evolve, and are also relevant to consider in regard to the design of cooperation studies.
This survey paper is concerned with vortex shedding from bodies in unsteady flow due either to time dependent motion of the body in a still fluid or unsteady motion of the fluid about a fixed body. The fluid is treated as incompressible, and the main emphasis is on starting flows and oscillatory flows. Much of the discussion describes 2D flow around sections of long or slender bodies. The first part of the paper covers the inviscid flow scaling of the forces induced by vortex shedding in time dependent flows which drive the shedding. This is followed by application of Wu’s impulse integral of the moment of vorticity to predict the forces induced by vortex shedding from a body in both inviscid and viscous flows. Vortex shedding phenomena involving small amplitude, high-frequency oscillatory flow such as vortex-induced vibration (VIV) and fluid-structure interaction (FSI) are not included in this discussion as in these cases the unsteady flow controls rather than drives the vortex shedding and they are well covered elsewhere.
The second part of the paper describes a vortex force mapping (VFM) method derived by considering the Lamb–Gromyko formulation for the pressure contribution which allows the integral of the vorticity field to be restricted to regions which are not far from the body. It is applied to both inviscid and viscous flows. The section finishes with discussion of application of the VFM to the calculation of forces induced on bodies from flow field measurements, such as particle image velocimetry (PIV).
This article examines one of the most violent episodes in Mexico’s recent history—the Corpus Thursday massacre orchestrated by the Mexican government against young students on June 10, 1971. The event marked the beginning of a period known as the guerra sucia (dirty war), marked by the systematic repression of students and dissenting political groups by government forces. The present work advocates for “making history with photographs,” urging readers to explore the historical moment through the narratives presented by three distinct historical actors: the press, independent photographers, and the perspective of power from governmental organizations.
The present study aimed to investigate whether contextual factors influence how a reference is processed in discourse. We used intact and violated presuppositions (PSP), triggered by a definite or indefinite noun phrase, to monitor the reference process. In one sentence set, a contextual referent was explicitly mentioned close or far from the PSP-triggering noun phrase (memory context). In another sentence set, a referent was not explicitly mentioned in the context, but an inference to a referent was either plausible or implausible due to contextual semantic relations (inference context). Participants were asked to rate the coherence of the discourse after listening to it. Our results revealed a strong influence of the temporal distance of the contextual presentation of a referent. When the referent was far in the context (memory context), PSP violations were judged to be less severe than for close referents, suggesting that they are less clearly represented in memory. Furthermore, PSP violations seemed to play a subordinate role when the semantic context provided a basis for the plausible presence of a referent (inference context). Our results suggest that discourse comprehension involves referential processes whose importance may fade with distance in memory or may be obscured by semantic contextual content.