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This article uses techniques of microhistory to explore how Janbai, the third wife of Sir Tharia Topan, exerted economic, religious, and social influence in Indian Ocean networks. An Ismaili woman from a Gujarati trading family who lived in East Africa, Janbai lies outside of the social worlds that have dominated studies of Muslim modernity in South Asia, which centre on Sunni male professionals from North India. Janbai was illiterate and largely disconnected from textual debates about modernity. In fact, she was just the sort of woman that reformers castigated for their supposed attachment to religious superstitions and customary practices. In contrast, studying Janbai through an alternative frame of ‘material modernity’ reveals the complex biography of a women who neither conformed to the idealized ‘new’ woman, nor simply reproduced inherited practices. Instead, she navigated rapid social mobility, shifting geographies, and new technologies and institutions, particularly colonial law courts, in ways that echoed and departed from how women had long exercised agency. The article argues that scholars, by foregrounding textual archives and discursive analysis, have tended to reproduce the marginalization of women like Janbai. In contrast, looking to sources such as jewellery and photographs, and reading textual archives with greater attention to gendered patterns of consumption and investment, brings Janbai from the margins to the centre of our understanding of modernity. In addition to enriching our understanding of the lives of women, increased attention to materiality and visuality opens up critical new avenues for writing a more variegated history of Muslim modernity.
Suppressing mode degradation is the key issue for high-power laser delivery; however, diagnosing mode degradation in its entirety, ranging from the contents and origins to locations, has always been a major obstacle. Here, a versatile approach for tracing the origins of mode coupling is demonstrated through addressing the differential intermodal dispersions of fiber modes. Full recognition for modal contents and the origins of mode degradation are experimentally completed in a two-mode fiber laser delivery system, which assists a significant improvement of beam quality M2 from 1.35 to 1.15 at the highest power of over 300 W. This method yields a quantitative characterization for manipulating the individual mode of dual-mode coupling origins or their combinations. This work points toward a promising strategy for the online tracing of mode coupling in cascade fiber links, thus enabling further pursuit of seeking extreme beam quality in high-power fiber laser systems.
The Black-cheeked Lovebird Agapornis nigrigenis has a highly restricted range in dry south-western Zambia, where its distribution is clumped and localised in association with mopane Colophospermum mopane woodland and permanent water pools. Fieldwork and monitoring over 30 months between December 2018 and October 2021 established that the lovebirds’ usage of pools for drinking was higher towards the centre of the bird’s distribution and influenced by the pools’ proximity to mopane woodlands, surrounding tree cover, and level of human activity. Of the four pool types available for use by lovebirds (i.e. mopane, grassland, river, and artificial), mopane and grassland pools were disproportionally susceptible to drying out in the dry season, hence showed greater variation in numbers of visiting birds compared with the other two types. Lovebirds showed a preference for pools with a perimeter of <50 m and tended to avoid those with a perimeter >100 m, consistent with a positive association between pool size and human activity. Convergence between humans and lovebirds in dependence on water resources and mopane woodland points to the need to find ways to overcome potential conflicts. Such ways include creating small, shallow-sided, undisturbed pools in or near mopane woodland, extending water retention in existing mopane pools, and enhancing the capacity of artificial pools to meet the needs of the lovebirds.
This essay explores ways in which environmental educators might break with their existing traditions of research and pedagogy by critically appraising climate histories and anticipated futures depicted by SF (science/speculative fiction) in print and audio-visual media. SF has engaged the politics of climate change for at least two centuries and, as a form of public pedagogy accessible to all generations, provides alternative visualisations of the problems arising from humanity’s destructive transformations of Earth’s climate and possible ways of ameliorating them.
Climate change litigation is developing rapidly and pervasively, emerging as a space for legal innovation. Until now, this process has occurred mainly in national courts. The result is a decentralization of the interpretation of human rights relating to climate change. This article argues that such decentralization could, in principle, have a destabilizing impact on claims to the universality of human rights. However, close examination of this litigation shows that a prototype is emerging, certain features of which are becoming ‘hard wired’ through the process of judicial dialogue. By exploring the content of this prototype, its decentralized development, and its self-reinforcing nature, we see a legal space emerging in which environmental human rights sit between the universal and the contextual.
Modification of mRNA by methylation is involved in post-transcriptional regulation of gene expression by affecting the splicing, transport, stability and translation of mRNA. Methylation of adenosine at N6 (m6A) is one of the most common and important cellular modification occurring in the mRNA of eukaryotes. Evidence that m6A mRNA methylation is involved in regulation of stress response and that its dysregulation may contribute to the pathogenesis of neuropsychiatric disorders is accumulating. We have examined the acute and subchronic (up to 18 days once per day intraperitoneally) effect of the first METTL3/METTL14 activator compound CHMA1004 (methyl-piperazine-2-carboxylate) at two doses (1 and 5 mg/kg) in male and female rats. CHMA1004 had a locomotor activating and anxiolytic-like profile in open field and elevated zero-maze tests. In female rats sucrose consumption and swimming in Porsolt’s test were increased. Nevertheless, CHMA1004 did not exhibit strong psychostimulant-like properties: CHMA1004 had no effect on 50-kHz ultrasonic vocalizations except that it reduced the baseline difference between male and female animals, and acute drug treatment had no effect on extracellular dopamine levels in striatum. Subchronic CHMA1004 altered ex vivo catecholamine levels in several brain regions. RNA sequencing of female rat striata after subchronic CHMA1004 treatment revealed changes in the expression of a number of genes linked to dopamine neuron viability, neurodegeneration, depression, anxiety and stress response. Conclusively, the first-in-class METTL3/METTL14 activator compound CHMA1004 increased locomotor activity and elicited anxiolytic-like effects after systemic administration, demonstrating that pharmacological activation of RNA m6A methylation has potential for neuropsychiatric drug development.
This study aims to determine if there are differences in color–emotion association between monolingual speakers of Spanish and Mandarin, depending on how colors are presented (verbally or visually). We tested two groups of 25 speakers of these two languages in two different tasks using the Geneva Emotion Wheel, which encompasses 20 types of emotions. In Task 1, 13 colors were presented to participants as color terms in their native language, whereas in Task 2 the same colors were presented as color patches from the Munsell chart. Participants were then asked to associate color terms or color patches to the set of emotion concepts (and intensities of emotion) in the Geneva Emotion Wheel. Overall, differences between languages were not significant, regarding either the type of emotion or individual dimensions of emotion (valence, arousal or power), although significant differences were observed for specific colors. Also, Spanish speakers tended to attribute higher intensity values and higher numbers of emotion values to colors. At the same time, speakers of both languages reacted similarly to color presentation, with color terms being associated with the same emotions as color patches, but eliciting stronger reactions with respect to intensity and the number of emotion values. Finally, we found less variability in color–emotion associations within the Spanish-speaking group. Overall, our study points to a mixed pattern of universality and culture-specificity regarding how colors are used for conveying emotions by people.
An aberrant right subclavian artery represents the most common aortic arch vascular anomaly. Conventional wisdom states that these anomalies do not result in dysphagia, but rather serve as “red herrings”. Clearly, in the vast majority of cases, this holds true. Nonetheless, one should never say never.
Methods:
Herein, we present a cohort of four children with debilitating dysphagia resulting from an aberrant right subclavian artery. Subclavian reimplantation via a right posterolateral thoracotomy was performed successfully in all cases.
Results:
Dysphagia resolved postoperatively, and all patients were able to advance to a normal diet. They were able to gain appropriate weight postoperatively and continue to do well at most recent clinical follow-up.
Conclusions:
This case series suggests that aberrant right subclavian artery anatomy should be considered a potential aetiology of dysphagia, albeit rarely. Surgical intervention for select patients can provide dramatic resolution of symptoms.
We present high-resolution observations of nearby ($z\lesssim0.1$) galaxies that have hosted Type Ia supernovae to measure systemic spectroscopic redshifts using the wide field spectrograph (WiFeS) instrument on the Australian National University 2.3 m telescope at Siding Spring Observatory. While most of the galaxies targeted have previous spectroscopic redshifts, we provide demonstrably more accurate and precise redshifts with competitive uncertainties, motivated by potential systematic errors that could bias estimates of the Hubble constant ($H_0$). The WiFeS instrument is remarkably stable; after calibration, the wavelength solution varies by $\lesssim$0.5 Å in red and blue with no evidence of a trend over the course of several years. By virtue of the $25\times 38$ arcsec field of view, we are always able to measure the redshift of the galactic core, or the entire galaxy in the cases where its angular extent is smaller than the field of view, reducing any errors due to galaxy rotation. We observed 185 southern SN Ia host galaxies and measured the redshift of each via at least one spatial region of (a) the core and (b) the average over the full-field/entire galaxy. Overall, we find stochastic differences between historical redshifts and our measured redshifts on the order of $\lesssim10^{-3}$ with a mean offset of 4.3${\times 10^{-5}}$ and normalised median absolute deviation of 1.2${\times 10^{-4}}$. We show that a systematic redshift offset at this level is not enough to bias cosmology, as $H_0$ shifts by $+0.1$ km s$^{-1}$ Mpc$^{-1}$ when we replace Pantheon+ redshifts with our own, but the occasional large differences are interesting to note.
Plastic pollution is pervasive in our environment, with impacts seen across ecosystems and taxa. While plastic has become an integral part of our daily lives, not all of it is readily apparent, making it challenging to effectively reduce plastic pollution. A hidden source of plastic pollution is plastic-based printing, which is used on a wide range of items including single-use products like plastic food containers and multi-use plastic items like credit cards. This also includes items that we would not consider to be sources of plastic pollution such as glass bottles with surface printing. The widespread use of this printing, therefore, results in even non-plastic items contributing to plastic pollution, potentially contaminating recycling streams and exacerbating nano- and microplastic (NMP) dispersion. Given the challenges of remediating NMP plastic pollution once it has entered the environment, prevention becomes paramount. With significant efforts underway to reduce plastic production, it is important to take a holistic approach to redesigning objects and materials to avoid false solutions, which will continue to contribute to ecosystem degradation and planetary boundary transgressions. To make meaningful progress and avoid ineffective solutions, it is imperative to consider all sources of plastic pollution, including those concealed within apparently non-plastic objects.
The 2019 coronavirus (COVID-19) pandemic and strict quarantine increased the likelihood of mental symptoms and abnormal eating behaviours. This study aimed to assess the magnitude of emotional eating (EE) among nurses working in Lebanese hospitals and its association with mental health. A cross-sectional study was conducted among nurses aged between 18 and 50 years working in Lebanese hospitals during the COVID-19 outbreak and the economic crisis. A total of 303 nurses consented to participate. The mean EE score was 28.56 (±8.11). The results of this study revealed that 53.8% of the nurses reported depression, 58.1% suffered from anxiety and 95.1% experienced either moderate or severe stress. The study concluded that females (β = 8.112, P = 0.004), non-smokers (β = –4.732, P = 0.01) and depressed nurses (β = 0.596, P = 0.046) had a higher tendency towards EE. Additionally, it was found that EE was associated with weight gain (β = 6.048, P = 0.03) and increased consumption of fried foods (β = 5.223, P = 0.001). Females experienced more stress (β = 2.244, P = 0.003) and anxiety (β = 1.526, P = 0.021) than their male counterparts. With regard to mental health, depression was associated with weight gain (β = 2.402, P = 0.003) and with lower consumption of healthy foods such as nuts (β = –1.706, P = 0.009) and dishes prepared with sofrito sauce (β = –1.378, P = 0.012). These results can help the health authorities to design preparedness plans to ensure proper mental and physical well-being of nurses during any unforeseen emergencies.
Our aim was to explore the experiences of individuals receiving emergency department (ED) care for acute headaches.
Background:
Patients with headache exacerbations commonly present to EDs. This study explored the experiences of adult patients during the exacerbation period, specifically using photovoice.
Methods:
Recruited from two urban EDs in Alberta, Canada, participants with primary headaches took photographs over 3–4 weeks and subsequently completed a 60–90 minute, one-on-one, in-person photo-elicitation interview. Interviews were audio recorded, transcribed and thematically analyzed alongside photographs.
Results:
Eight participants (six women) completed the study. The average age was 42 years (standard deviation: 16). Five themes emerged: (1) the struggle for legitimacy in light of the invisibility of their condition; (2) the importance of hope, hopelessness and fear in the day-to-day life of participants; (3) the importance of agency and becoming “your own advocate”; (4) the struggle to be and be seen as themselves despite the encroachment of their headaches; and (5) the realities of “good” and “bad” care in the ED. Participants highlighted examples of good care, specifically when they felt seen and believed. Additionally, some expressed the acute care space itself being a beacon of hope in the midst of their crisis. Others felt dismissed because providers “know it’s not life or death.”
Conclusions:
This study highlighted the substantial emotional impact that primary headaches have on the lives of participants, particularly during times of exacerbation and while seeking acute care. This provides insight for acute care settings and practitioners on how to effectively engage with this population.
Indigenous-owned businesses in Australia are strong employers of Indigenous people, maintaining rates of Indigenous employment that are not seen across the breadth of the Australian economy. Despite an increasing focus from governments and private organisations to improve rates of Indigenous employment, there is limited evidence to suggest that substantial improvements are being made. Despite acknowledgement from government of the crucial role played by Indigenous employers in creating Indigenous employment, there has been little focus on what may be learned from the Indigenous business sector in informing public and private Indigenous workplace and recruitment policies. Given the significantly strong levels of Indigenous employment in Indigenous-owned businesses, it is important to interrogate the extent to which this employment differs from that in non-Indigenous businesses and the potential explanations for such divergence. Using data from Supply Nation (2,291 Indigenous-owned businesses) and a survey of 680 non-Indigenous businesses, this paper finds that Indigenous businesses employ Indigenous people at a rate 12 times higher than non-Indigenous businesses. Regression analyses and Oaxaca–Blinder decompositions reveal that these divergent employment outcomes cannot be explained by the broad characteristics of the two sectors (such as industry, location, or profit status). These findings help confirm that the unique workplace practices of Indigenous businesses may explain their strong Indigenous employment and, therefore, provide the template for all Australian businesses to be better employers of Indigenous people.
This commentary argues that the current academic and societal pursuit of ‘solutions’ to sustainability challenges fails to acknowledge how change normally occurs in complex adaptive systems, that is, socio-economic systems and the Earth system, relevant for societal development. Such systems seldom evolve through isolated changes or ‘solutions’ but, rather, through numerous small adjustments of component parts. It is the interactions between these small adjustments that lead to system change. Thus, we argue the need for altered expectations in relation to, and a new narrative describing, the anticipated role of research in the pursuit of a more sustainable societal development trajectory.
Technical summary
The commentary argues for seeking multiple adjustments rather than seeking ‘solutions’ to our current planetary crises. Based on the belief that many of these adjustments may already lie dormant across academic departments, the University of Copenhagen conducted a series of ‘Transformation Labs’ in 2023 with the purpose of identifying the potential socio-economic and technical adjustments that, in combination, may catalyze societal transformation toward sustainability as well as potential barriers for their societal implementation. Here, we reflect on the learnings from the exercise and argue that both current funding practices and university training should be modified to support this altered narrative. In addition, interactions between research institutions and the beyond-academic world should be strengthened.
Social media summary
For reaching a sustainable trajectory, research needs to focus on multiple adjustments rather than fixed solutions.
American and European adults prefer natural products and often pay premiums to purchase natural products. They may do this because they believe natural products are better, either functionally or inherently. We present a measure that assesses belief in the ‘benevolence of nature’ across a range of products and a range of situations, including safety, sensory appeal, and effectiveness. American adults show a substantial belief in the benevolence of nature. This belief is sometimes erroneous, with participants attributing higher quality to some natural products that are in fact inferior to their artificial counterparts. In support of the belief that natural products are inherently better, many participants express a preference for a natural as opposed to an artificial product when both are stipulated to be chemically identical or to have identical effects. An original set of 24 items to measure belief in the benevolence of nature is refined into a more useful 10-item scale, and correlations with related scales are assessed. Belief in the benevolence of nature is not lower in participants who have experienced at least one natural disaster.
The Chinese pangolin Manis pentadactyla is categorized as Critically Endangered on the IUCN Red List but little is known about its status in Nepal. Although indirect sign surveys have reported its presence in several community forests in Kavrepalanchok district, no photographic or video evidence has previously been documented. We used camera traps to investigate the occurrence of pangolins in 20 community forests in Panauti Municipality in Kavrepalanchok. A total of 75 0.01 km2 plots were surveyed using camera traps during September 2022–February 2023, with a total survey effort of 803 trap-days. The cameras recorded a total of 16 individual video footage events of Chinese pangolins in six of the community forests. This is the first camera-trap evidence of the species' presence in these forest patches, and in Kavrepalanchok district. The pangolins displayed behaviours such as sniffing, gathering plant material and digging, between 18.00 and 1.00. The camera-trap records provide more accurate species identification and reliable information than indirect sign surveys, indicating camera traps are a useful surveying tool for rare, nocturnal and elusive pangolins.
During the past 30 yr an impasse has developed in the discovery and commercialization of synthetic herbicides with new molecular targets and novel chemistries. Similarly, there has been little success with bioherbicides, both microbial and chemical. These bioherbicides are needed to combat fast-growing herbicide resistance and to fulfill the need for more environmentally and toxicologically safe herbicides. In response to this substantial and growing opportunity, numerous start-up companies are utilizing novel approaches to provide new tools for weed management. These diverse new tools broaden the scope of discovery, encompassing advanced computational, bioinformatic, and imaging platforms; plant genome–editing and targeted protein degradation technologies; and machine learning and artificial intelligence (AI)-based strategies. This review contains summaries of the presentations of 10 such companies that took part in a symposium held at the WSSA annual meeting in 2024. Four of the companies are developing microbial bioherbicides or natural product–based herbicides, and the other six are using advanced technologies, such as AI, to accelerate the discovery of herbicides with novel molecular target sites or to develop non-GMO, herbicide-resistant crops.
The last 15–20 years have seen the emergence of a new trajectory of ‘Muslim feminism’ in India which has grounded Muslim women’s rights discourse both in the direct interpretation of Islamic scriptures and also in principles derived from the Indian Constitution. Examining two prominent Muslim women’s organizations—the All India Muslim Women’s Personal Law Board and the Bharatiya Muslim Mahila Andolan—this article examines how this form of Muslim feminism has become a central repository of Islamic modernist thought in India in light of its perceived failure in some other sections of Muslim public life. Based on writings and educational materials produced by these organizations, this article discusses their methods of harnessing the teachings of the Quran, their application of ‘Islamic feminist’ methodology to interpret Islamic family laws, their identification of equivalence between Islamic and constitutional values, and their attempts to engage the state in their efforts to promote the modernization of Muslim Personal Law.
I argue that the use of elected political representatives undermines the political equality of citizens. Having elected representatives politically stand-in for individual constituents makes ordinary citizens the political inferiors of their representatives. This in turn creates democratically problematic social inequality between elected politicians and their constituents. I then offer an alternative to representative politicians that does not face the avatar of the people problem: representative mini-publics. Through these bodies, we can achieve a representative system without a class of political elites, where citizens share the responsibilities and powers of government as equals.