Leptospirosis is a bacterial zoonosis that poses an increasing global public health risk. Pacific Island communities are highly vulnerable to leptospirosis outbreaks, yet the local drivers of infection remain poorly understood. We conducted a systematic review to identify the drivers of human Leptospira infection in the Pacific Islands. There were 42 included studies from which findings were synthesized descriptively. In tropical Pacific Islands, infections were a product of sociodemographic factors such as male gender/sex, age 20 to 60 years, Indigenous ethnicity, and poverty; lifestyle factors such as swimming, gardening, and open skin wounds; and environmental factors, including seasonality, heavy rainfall, and exposure to rodents, cattle, and pigs. Possible mitigation strategies in these islands include strengthening disease reporting standards at a regional level; improving water security, rodent control, and piggery management at a community level; and information campaigns to target individual-level drivers of infection. By contrast, in New Zealand, exposures were predominantly occupational, with infections occurring in meat and farm workers. Accordingly, interventions could include adjustments to occupational practices and promoting the uptake of animal vaccinations. Given the complexity of disease transmission and future challenges posed by climate change, further action is required for leptospirosis control in the Pacific Islands.

We determine the order of the k-core in a large class of dense graph sequences. Let $G_n$ be a sequence of undirected, n-vertex graphs with edge weights $\{a^n_{i,j}\}_{i,j \in [n]}$ that converges to a graphon $W\colon[0,1]^2 \to [0,+\infty)$ in the cut metric. Keeping an edge (i,j) of $G_n$ with probability ${a^n_{i,j}}/{n}$ independently, we obtain a sequence of random graphs $G_n({1}/{n})$. Using a branching process and the theory of dense graph limits, under mild assumptions we obtain the order of the k-core of random graphs $G_n({1}/{n})$. Our result can also be used to obtain the threshold of appearance of a k-core of order n.

This article examines the regulatory landscape of financial data access within the European Union, emphasising the implications and effectiveness of recent legislative initiatives. It provides an in-depth analysis of the Financial Data Access Regulation (FIDA) proposal and its relationship with existing laws, focusing on the possibilities for data access and utilisation in the context of Open Finance. The discussion evaluates the regulatory framework for automated decision-making (ADM) in European financial law, highlighting its strengths and identifying areas for improvement. By exploring the intersections of tech resilience, financial regulation, and data protection, the article aims to clarify the practical implications of current and proposed rules, emphasising effective practices and areas needing further legislative attention.

After 78 years of democracy, Italy continues to grapple with its recent past in the political, social, and cultural spheres. Its experience of fascism under Mussolini, its dual participation in the Second World War, and the continuous and still existent connections between the ideological factions of the 1930s–1940s and now render the country a rich case for the study of public history and memory. The specificity of these characteristics has often made Italian history and memory look like an outlier, shaped by circumstances difficult to compare with those of other countries'. This paper argues that contemporary Italian memory politics are in reality a valuable source of information about the kind of mnemonic discourses that may arise in other (Western) European countries, given the increasingly polarised and populist European landscape. Our study of discourses put forwarded by the post-fascist party Fratelli d'Italia reveals a set of mnemonic tools with which they successfully banalise fascism and chip at Italian public discourse slowly but surely. The comparison between this discourse and that of VOX and AfD in Spain and Germany, respectively, shows that these tools, ranging from nativism to policy (de)legitimation linked to fascist imagery, has started to transfer to other countries' political strategies.

Enrollment into a prospective cohort study of mother–preterm infant dyads during the COVID-19 pandemic progressed slower than anticipated. Enrollment occurred during the first week after preterm birth, while infants were still hospitalized. We hypothesized that slower enrollment was attributable to mothers testing positive for COVID-19 as hospital policies restricted them from entering the neonatal intensive care unit, thus reducing interactions with research staff. However, only 4.5% of 245 screened mothers tested COVID-19 positive. Only 24.9% of those screened, far fewer than anticipated, were eligible for enrollment. Assumptions about pandemic-related enrollment barriers were not substantiated in this pediatric cohort.

Despite stroke being one of the major and increasing burdens to global health, therapeutic interventions in intracerebral haemorrhage (ICH) continue to be a challenge. Existing treatment methods, such as surgery and conservative treatment have shown limited efficacy in improving the prognosis of ICH. However, more and more studies show that exploring the specific process of immune response after ICH and taking corresponding immunotherapy may have a definite significance to improve the prognosis of cerebral haemorrhage. Therefore, immune interventions are currently under consideration as therapeutic interventions in the ICH. In this review, we aim to clarify unique immunological features of stroke, and consider the evidence for immune interventions. In acute ICH, activation of glial cells and cell death products trigger an inflammatory cascade that damages vessels and the parenchyma within minutes to hours of the haemorrhage. Immune interventions that ameliorate brain inflammation, vascular permeability and tissue oedema should be administered promptly to reduce acute immune destruction and avoid subsequent immunosuppression. A deeper understanding of the immune mechanisms involved in ICH is likely to lead to successful immune interventions.

How well do existing survey instruments differentiate between opinions that affect individual behavior and opinions that don't? To answer this question, we randomly assigned U.S. respondents to one of three survey instruments: Likert items (Likert), Likert items followed by personal importance items (Likert+) and Quadratic Voting for Survey Research (QVSR), which gives respondents a fixed budget to buy “favor” or “oppose” votes, with the price for each vote increasing quadratically. We find that, relative to Likert, both Likert+ and QVSR better identify people who care enough about an issue to act in opinion-congruent ways, with QVSR offering the most consistent improvement overall. Building on these results, we show how conclusions regarding the relationship between policy opinions and self-interest can differ across measurement strategies.

We provide decadal estimates of GDP per capita for the Russian Empire from the 1690s to the 1880s, making it possible for the first time to compare the economic performance of one of the world’s largest economies with other countries. Significant Russian economic growth before the 1760s resulted in catching-up on northwest Europe, but this was followed by a period of negative growth between the 1760s and 1800s and stagnation from the 1800s to the 1880s, leaving late-nineteenth century Russia further behind the West than at the beginning of the eighteenth century.

SARS-CoV-2 superspreading occurs when transmission is highly efficient and/or an individual infects many others, contributing to rapid spread. To better quantify heterogeneity in SARS-CoV-2 transmission, particularly superspreading, we performed a systematic review of transmission events with data on secondary attack rates or contact tracing of individual index cases published before September 2021 prior to the emergence of variants of concern and widespread vaccination. We reviewed 592 distinct events and 9,883 index cases from 491 papers. A meta-analysis of secondary attack rates identified substantial heterogeneity across 12 chosen event types/settings, with the highest transmission (25–35%) in co-living situations including households, nursing homes, and other congregate housing. Among index cases, 67% reported zero secondary cases and only 3% (287) infected >5 secondary cases (“superspreaders”). Index case demographic data were limited, with only 55% of individuals reporting age, sex, symptoms, real-time polymerase chain reaction (PCR) cycle threshold values, or total contacts. With the data available, we identified a higher percentage of superspreaders among symptomatic individuals, individuals aged 49–64 years, and individuals with over 100 total contacts. Addressing gaps in the literature regarding transmission events and contact tracing is needed to properly explain the heterogeneity in transmission and facilitate control efforts for SARS-CoV-2 and other infections.

Downy brome (Bromus tectorum L.) is a difficult species to control in the dryland wheat (Triticum aestivum L.) production areas of northeastern Oregon. The selection of herbicide-resistant B. tectorum populations has further complicated B. tectorum management. A survey of wheat growers was conducted in 2021 and 2022 to understand B. tectorum management practices. The survey included four questions based on the growing seasons from 2017 to 2022 related to crop rotation, tillage versus no-tillage, irrigation versus dryland, and herbicide programs. To determine the extent of herbicide resistance, seeds were collected from 49 B. tectorum populations in wheat fields in northeastern Oregon and tested for resistance. Herbicides tested were clethodim, glyphosate, imazamox, mesosulfuron, metribuzin, propoxycarbazone, pyroxasulfone, pyroxsulam, quizalofop, and sulfosulfuron. Winter wheat–summer fallow rotation was the most predominant cropping system in the region. Most of the fields were in no-tillage systems, and none were irrigated. Pyroxasulfone applied preemergence and acetolactate synthase (ALS) inhibitors applied postemergence were the most often used herbicides for B. tectorum control in winter wheat. Glyphosate was the most frequently used herbicide for B. tectorum control in summer fallow. Resistance screenings confirmed that 46 of the 49 B. tectorum populations were resistant to ALS inhibitors with different cross-resistance patterns. Two populations were resistant to metribuzin and exhibited multiple resistance to ALS inhibitors. All populations were susceptible to clethodim, glyphosate, pyroxasulfone, and quizalofop. The widespread occurrence of ALS inhibitor–resistant B. tectorum populations limits effective postemergence herbicide options in winter wheat.

What are the psychological mechanisms of racial “dog whistles” in American politics? Literature on race priming in American politics argues when race is primed implicitly, racial biases influence political evaluations, but when race is made salient, individuals can use controlled processing to inhibit automatic biases and abide by egalitarian norms. However, the neural mechanisms underlying these processes have yet to be examined directly. In a 2 × 2 within-groups experiment using functional magnetic resonance imaging, we examine these neural mechanisms. We find brain areas associated with conflict detection, evaluative processing, and controlled processing are more active when race is primed explicitly rather than implicitly, as expected, although we do not find substantial brain activation associated with automatic responses to be more active during implicit than explicit primes. Results are discussed in terms of understanding how racial cues influence political evaluations while considering America’s ever-changing racial norms.