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We use three-dimensional direct numerical simulations of homogeneous isotropic turbulence in a cubic domain to investigate the dynamics of heavy, chiral, finite-size inertial particles and their effects on the flow. Using an immersed-boundary method and a complex collision model, four-way coupled simulations have been performed, and the effects of particle-to-fluid density ratio, turbulence strength and particle volume fraction have been analysed. We find that freely falling particles on the one hand add energy to the turbulent flow but, on the other hand, they also enhance the flow dissipation: depending on the combination of flow parameters, the former or the latter mechanism prevails, thus yielding enhanced or weakened turbulence. Furthermore, particle chirality entails a preferential angular velocity which induces a net vorticity in the fluid phase. As turbulence strengthens, the energy introduced by the falling particles becomes less relevant and stronger velocity fluctuations alter the solid phase dynamics, making the effect of chirality irrelevant for the large-scale features of the flow. Moreover, comparing the time history of collision events for chiral particles and spheres (at the same volume fraction) suggests that the former tend to entangle, in contrast to the latter which rebound impulsively.
Engaging diverse partners in each phase of the research process is the gold standard of community-engaged research and adds value to the impact of implementation science. However, partner engagement in dissemination, particularly meaningful involvement in developing peer-reviewed manuscripts, is lacking. The Implementation Science Centers in Cancer Control are using the Translational Science Benefits Model to demonstrate the impact of our work beyond traditional metrics, including building capacity and promoting community engagement. This paper presents a case example of one center that has developed a policy for including community partners as coauthors. Standard practices are used to foster clear communications and bidirectional collaboration. Of published papers focused on center infrastructure and implementation research pilots, 92% have community partner coauthors. This includes 21 individuals in roles ranging from physician assistant to medical director to quality manager. Through this intentional experience of co-creation, community partners have strengthened implementation science expertise. Community coauthors have also ensured that data interpretation and dissemination reflect real-world practice environments and offer sustainable strategies for rapid translation to practice improvements. Funders, academic journals, and researchers all have important roles to play in supporting community coauthors as critical thought partners who can help to narrow the gap between research and practice.
The importance of habitat-forming species, particularly cold-water corals like Dendrophyllia ramea, cannot be overstated as they provide crucial physical structures that offer shelter, food, and breeding habitat for a range of other species. We studied the spatial distribution and abundance of D. ramea, its associated species and the impact of human activities in a population of the Herradura, Granada in the western Mediterranean. Video transects were conducted at different depths, and epibiont samples were collected to describe the coral assemblage and the diversity of associated organisms. Dendrophyllia ramea presented high abundances at an unusually shallow depth in the Mediterranean, ranging from 30 to 48 m, despite typically being found between 50 and 500 m, with recordings indicating occurrences as deep as 1000 m, and hosting a high number of epibionts and macro-benthic organisms associated with coral reefs. Bryozoans showed a close relationship with D. ramea as they are important components of both the reef and the epibiont community. This study identified 63 new species and 15 new genera associated with cold-water corals. This study showed the importance of D. ramea as a nursery site, even for other habitat-forming species. The major threat to this community is human activity (fishing, littering and free anchoring), with the most abundant types of waste being rubber, glass/ceramics, and plastic polymers, and many fishing lines and nets damaging the corals. Overall, this study emphasises the urgent need to protect cold-water corals and their associated species and reduce the impact of human activities on marine ecosystems.
We characterize the fractional Dehn twist coefficient (FDTC) on the n-stranded braid group as the unique homogeneous quasimorphism to $\mathbb {R}$ of defect at most 1 that equals 1 on the positive full twist and vanishes on the $(n-1)$-stranded braid subgroup. In a different direction, we establish that the slice-Bennequin inequality holds with the FDTC in place of the writhe. In other words, we establish an affine linear lower bound for the smooth slice genus of the closure of a braid in terms of the braid’s FDTC. We also discuss connections between these two seemingly unrelated results. In the appendix, we provide a unifying framework for the slice-Bennequin inequality and its counterpart for the FDTC.
We prove a general formula that relates the parity of the Langlands parameter of a conjugate self-dual discrete series representation of $\operatorname { {GL}}_n$ to the parity of its Jacquet-Langlands image. It gives a generalization of a partial result by Mieda concerning the case of invariant $1/n$ and supercuspidal representations. It also gives a variation of the result on the self-dual case by Prasad and Ramakrishnan.
This study contributes to an emerging body of research that combines new mobilities and gerontological perspectives. Most previous studies on older adults’ mobilities have analysed data collected at a single point in time and there is a need for studies that explore the meanings of movement and non-movement over time, especially in relation to unexpected life events. This work explores the meanings of older adults’ abruptly changing everyday (im)mobilities before and during the Covid-19 pandemic. It draws from qualitative interviews conducted with 11 older adults in a Finnish suburb in autumn 2019 and spring 2020, and focuses on grocery shopping, which most of the participants did themselves before the pandemic, but not during it. The findings provide insight into how meanings of everyday (im)mobilities are formed as older individuals (re)negotiate their relationships with their changing places of ageing. The participants’ views of their disrupted everyday mobilities were shaped by active person–place engagements. On one hand, the findings highlight that individuals are not at the mercy of their circumstances; they possess agency that can enable maintaining a sense of self and independence even in restricted mobility situations. On the other hand, the findings reveal relationalities that explain why sudden mobility loss often leads to diminished wellbeing. The relational nature of the meanings of (im)mobility implies that there is no one-size-fits-all approach to supporting older adults who face mobility difficulties while ageing in their homes. It is crucial to recognise the diversity of older adults and to support their individual lifestyles.
Sea turtle populations have significantly declined in recent years due to anthropogenic causes. Historical stranding records in the Canary Islands archipelago (Spain) reveal a high frequency of Caretta caretta and Chelonia mydas strandings. Our study aims to comprehensively characterize and explore these stranding records. Additionally, we have investigated the interactions between sea turtles and the island's professional fishers, seeking insights from small-scale artisanal fishers to understand the current state of sea turtle populations. The results have shown that Tenerife stands out with the highest number of sea turtle strandings, recording 1875 strandings over a span of 23 years. The primary cause of sea turtle stranding's is the interaction with fishing gear, specifically nets and hooks. Moreover, our research has highlighted the need for improved knowledge and training on how to handle stranded sea turtles within the fishing sector. Consequently, raising awareness and implementing conservation plans for sea turtle populations in Tenerife is of outmost importance in addressing and improving the current situation.
While factors such as age and education have been associated with persistent differences in functional cognitive decline, they do not fully explain observed variations particularly those between different racial/ethnic and sex groups. The aim of this study was to explore the association between allostatic load (AL) and cognition in a racially diverse cohort of young adults.
Methods:
Utilizing Wave V of the National Longitudinal Study of Adolescent to Adult Health – a nationally representative, longitudinal survey of adults aged 34–44, this study utilized primary data from 10 immune, cardiovascular, and metabolic biomarkers to derive an AL Index. Cognition was previously recorded through word and number recall scores. Regression analysis evaluated the association between cognitive recall, AL, age, sex, and race/ethnicity.
Results:
Regression results indicated statistically higher AL scores among Blacks (IRR = 1.09, CI = 1.01, 1.19) compared to Whites and lower AL score among females compared to males (IRR = 0.76, CI = 0.72, 0.81). At zero AL, Blacks (IRR = 1.2399, CI = 1.2398, 1.24) and Other races (IRR = 1.4523, CI = 1.452, 1.4525) had higher recall while Hispanics (IRR = 0.808, CI = 0.8079, 0.8081) had lower recall compared to Whites. Relative to males, females had higher number recall (IRR = 1.1976, CI = 1.1976, 1.1977). However, at higher, positive levels of AL, Blacks (IRR = 0.9554, CI = 0.9553, 0.9554), Other races (IRR = 0.9479, CI = 0.9479, 0.9479) and females (IRR = 0.9655, CI = 0.9655, 0.9655) had significantly lower number recall than Whites and males respectively.
Conclusions:
Race and sex differences were observed in recall at different levels of AL. Findings demonstrate the need for further exploration of cognition in young adults across diverse populations that includes examination of AL.
Suicide is one of the major causes of premature death in patients diagnosed with a schizophrenia-spectrum psychotic disorder. However, associations between psychotic-like experiences in youth and suicidality in later life remain under-researched.
Aims
We aimed to investigate any associations between early experiences of thought interference and auditory-verbal hallucinations (AVHs) with first-rank symptoms of schizophrenia and suicidal thoughts and behaviours in adulthood.
Method
This study used data from the Avon Longitudinal Study of Parents and Children (ALSPAC). We calculated combined thought interference score at ages 11 years 8 months, 13 years 1 month, 14 years 1 month and 16 years 6 months. We also assessed AVHs at the same age points. For outcome variables, we used specific variables measuring delusions of control, AVHs and suicidality at 24 years of age. We carried out logistic regressions and mediation analyses to assess the relationships among these variables.
Results
Thought interference and AVHs at all ages throughout childhood and adolescence were associated with suicidal thoughts and behaviours, and also with clinically more significant symptoms of delusions of control and AVHs at age 24. Substance use-induced psychotic-like experiences mediated a large proportion of the relationship between early psychotic-like experiences and suicidality in later life.
Conclusions
Thought interference and AVHs in childhood and adolescence are associated with first-rank symptoms and suicidality in adulthood. Mental health interventions in children and adolescents need to take into account the impact of specific psychotic-like experiences and allow for the early detection of thought interference and AVH-related symptoms.
The effectiveness of teaching strategies and resources that promote meaningful content learning is most pronounced when active methods such as project-based learning (PBL) are used to teach Ancient History (Molina, 2020, 53). Therefore, this study focuses on a comprehensive assessment of the methodological and historical competences acquired by students enrolled in the secondary education teacher training programme at the University of Cordoba (Spain). The research, which is non-experimental and quantitative, uses a Likert-type scale and involves the participation of 201 Masters students who have completed the course ‘Learning and Teaching Social Sciences’. The results of the statistical analysis show a positive evaluation of PBL in terms of historical understanding and its effectiveness in improving historical awareness. It is crucial to emphasise the advantages of active and collaborative learning inherent in PBL. However, it is also imperative to acknowledge the challenges that students face in applying their methodological knowledge to the secondary school setting. The transition from theoretical understanding to practical implementation is a significant hurdle for many students aspiring to a career in education. These findings underline the importance of promoting the seamless integration of innovative pedagogical approaches into teacher training programmes in order to effectively address the specific challenges of teaching antiquity in an educational context. Finally, this research was made possible by the Ministry of Science and Innovation's ‘Prueba de Concepto’ project, funded by the European Union under grant number PDC2022-133123-I00, and also by the CLIOGEN project (GINDO-UB/187) on Ancient History.
Among participants with Alzheimer's disease (AD) we estimated the minimal clinically important difference (MCID) in apathy symptom severity on three scales.
Design:
Retrospective anchor- and distribution-based analyses of change in apathy symptom scores.
Setting:
Apathy in Dementia Methylphenidate Trial (ADMET) and ADMET 2 randomized controlled trials conducted at three and ten clinics specialized in dementia care in United States and Canada, respectively.
Participants:
Two hundred and sixty participants (60 ADMET, 200 ADMET 2) with clinically significant apathy in Alzheimer’s disease.
Measurements:
The Clinical Global Impression of Change in Apathy scale was used as the anchor measure and the MCID on the Neuropsychiatric Inventory – Apathy (NPI-A), Dementia Apathy Interview and Rating (DAIR), and Apathy Evaluation Scale-Informant (AES-I) were estimated with linear mixed models across all study visits. The estimated thresholds were evaluated with performance metrics.
Results:
Among the MCID was a decrease of four points (95% CI: −4.0 to −4.8) on the NPI-A, 0.56 points (95% CI: −0.47 to −0.65) on the DAIR, and three points on the AES-I (95% CI: −0.9 to −5.4). Distribution-based analyses were largely consistent with the anchor-based analyses. The MCID across the three measures showed ∼60% accuracy. Sensitivity analyses found that MMSE scores and apathy severity at baseline influenced the estimated MCID.
Conclusions:
MCIDs for apathy on three scales will help evaluate treatment efficacy at the individual level. However, the modest correspondence between MCID and clinical impression of change suggests the need to consider other scales.
Salt is often present in the snow overlying seasonal sea ice, and has profound thermodynamic and electromagnetic effects. However, its provenance and behaviour within the snow remain uncertain. We describe two investigations tracing upward brine movement in snow: one conducted in the laboratory and one in the field. The laboratory experiments involved the addition of dyed brine to the base of terrestrial snow samples, with subsequent wicking being measured. Our field experiment involved dye being added directly (without brine) to bare sea-ice and lake ice surfaces, with snow then accumulating on top over several days. On the sea ice, the dye migrated upwards into the snow by up to 5 cm as the snow's basal layer became more salty, whereas no migration occurred in our control experiment over non-saline lake ice. This occurred in relatively dry snowpacks where brine took up $< 6\%$ of the snow's calculated pore volume, suggesting pore saturation is not required for upward salt transport. Our results highlight the potential role of microstructural parameters beyond those currently retrievable with penetrometry, and the potential value of longitudinal, process-based field studies of young snowpacks.
Most of the Ross Sea has been designated a marine protected area (MPA), proposed ‘to protect ecosystem structure and function’. To assess effectiveness, the Commission for the Conservation of Antarctic Marine Living Resources (CCAMLR) selected Adélie (Pygoscelis adeliae) and emperor (Aptenodytes forsteri) penguins, Weddell seals (Leptonychotes weddellii) and Antarctic toothfish (Dissostichus mawsoni) as ecosystem change ‘indicator species’. Stable for decades, penguin and seal populations increased during 1998–2018 to surpass historical levels, indicating that change in ecosystem structure and function is underway. We review historical impacts to population trends, decadal datasets of ocean climate and fishing pressure on toothfish. Statistical modelling for Adélie penguins and Weddell seals indicates that variability in climate factors and cumulative extraction of adult toothfish may explain these trends. These mesopredators, and adult toothfish, all prey heavily on Antarctic silverfish (Pleuragramma antarcticum). Toothfish removal may be altering intraguild predation dynamics, leading to competitive release of silverfish and contributing to penguin and seal population changes. Despite decades of ocean/weather change, increases in indicator species numbers around Ross Island only began once the toothfish fishery commenced. The rational-use, ecosystem-based viewpoint promoted by CCAMLR regarding toothfish management needs re-evaluation, including in the context of the Ross Sea Region MPA.
In the history of the left, the conjuncture 1914–1917 is the “bifurcation point” per definition. Leaving an enduring mark on the labor movement, it also shaped subsequent historiographies. For the pro-Bolshevik left, 1914 epitomized the betrayal of a group of reformist leaders. Conversely, anti-communist social democrats regarded the Second International as an uncomfortable political heritage. Despite irreconcilable disputes, both traditions shared a lack of interest in defending the period 1889–1914, let alone delving into its history. The real take-off of Second International historiography came later and coincided with the outset of the Cold War, experiencing a “golden age” in the 1960s and 1970s. Studies of socialism lost momentum from the 1980s onwards, but the last 15 years have seen a resurgence of interest in the Second International and even a popular reappraisal of Karl Kautsky. Linking historiography to wider social and political phenomena, this article reflects on this new interest in the Second International in both activist and academic circles. The first section summarizes the historical significance of the International and examines how the crisis of 1914 became a crucial “bifurcation point” with significant political and historiographical impact. The second section explores recent trends in scholarly research on the subject. The third section provides an analysis of the vindication of Karl Kautsky among radicals and socialists in the United States over the past 10 years. The conclusion summarizes the main arguments and reflects on the contribution this analysis can make to a discussion about the “long cycle” of socialism.
Many believe that weaker legal constraints make unilateral action easier to reverse than legislation. Yet in some cases, unilateralism survives a successor's determined opposition. I argue that legislative persistence and unilateral transience may arise not only from differences in legal status but also from a selection effect: unilateralism and subsequent rescission can both stem from weak underlying policy-demanding groups. But if unilateralism itself alters the landscape of group power through policy feedback effects, it can survive a purportedly opposed new president. An example is the Trump Administration's failure to depart from the Obama Justice Department's lax stance on cannabis. Weak constituents’ policy demands may thus need to rely on a sympathetic president's unilateral action to begin a feedback loop, subsequently softening opposition. This paper therefore identifies unilateral action as a key tool for shifting policy in an enduring way, explaining its success or failure in terms of interest group power.
Poor air quality can both trigger and aggravate lung and heart conditions, as well as affecting child development. It can even lead to neurological and mental health problems. However, the precise mechanisms by which air pollution affect human health are not well understood.
Aims
To promote interdisciplinary dialogue and better research based on a critical summary of evidence on air quality and health, with an emphasis on mental health, and to do so with a special focus on bioaerosols as a common but neglected air constituent.
Method
A rapid narrative review and interdisciplinary expert consultation, as is recommended for a complex and rapidly changing field of research.
Results
The research methods used to assess exposures and outcomes vary across different fields of study, resulting in a disconnect in bioaerosol and health research. We make recommendations to enhance the evidence base by standardising measures of exposure to both particulate matter in general and bioaerosols specifically. We present methods for assessing mental health and ideal designs. There is less research on bioaerosols, and we provide specific ways of measuring exposure to these. We suggest research designs for investigating causal mechanisms as important intermediate steps before undertaking larger-scale and definitive studies.
Conclusions
We propose methods for exposure and outcome measurement, as well as optimal research designs to inform the development of standards for undertaking and reporting research and for future policy.
Recent discoveries of multiple long-period pulsars (periods ${\sim}10\,$s or larger) are starting to challenge the conventional notion that coherent radio emission cannot be produced by objects that are below the many theorised death lines. Many of the past pulsar surveys and software have been prone to selection effects that restricted their sensitivities towards long-period and sporadically emitting objects. Pulsar surveys using new-generation low-frequency facilities are starting to employ longer dwell times, which makes them significantly more sensitive in detecting long-period or nulling pulsars. There have also been software advancements to aid more sensitive searches towards long-period objects. Furthermore, recent discoveries suggest that nulling may be a key aspect of the long-period pulsar population. We simulate both long-period and nulling pulsar signals, using the Southern-sky MWA Rapid Two-meter (SMART) survey data as reference and explore the detection efficacy of popular search methods such as the fast Fourier transform (FFT), fast-folding algorithm (FFA) and single pulse search (SPS). For FFT-based search and SPS, we make use of the PRESTO implementation, and for FFA we use RIPTIDE. We find RIPTIDE’s FFA to be more sensitive; however, it is also the slowest algorithm. PRESTO’s FFT, although faster than others, also shows some unexpected inaccuracies in detection properties. SPS is highly sensitive to long-period and nulling signals, but only for pulses with high intrinsic signal-to-noise ratios. We use these findings to inform current and future pulsar surveys that aim to uncover a large population of long-period or nulling objects and comment on how to make optimal use of these methods in unison.
Older adults are identified to have reduced social cognitive performance compared to younger adults. However, few studies have examined age-associations throughout later life to determine whether these reductions continue with advancing age.
Method:
This study assesses cross-sectional associations of emotion perception, cognitive and affective theory of mind (ToM), and emotional empathy in a healthy sample of 157 adults aged 50–89 years (M = 65.31, SD = 9.00, 68% female sex). Emotion perception, cognitive ToM, and affective ToM were measured using The Awareness of Social Inference Test Short Form (TASIT-S), while affective ToM was also measured using Reading the Mind in the Eyes Revised (RME-R). Emotional empathy was measured using the Empathy Quotient.
Results:
Multiple regression analyses, adjusting for multiple comparisons, revealed a moderate negative association between age and emotion perception for all emotions combined, as well as for sad and revolted expressions, but not happy, neutral, anxious, or angry expressions. Age had a negative, moderate association with first-order cognitive, second-order cognitive, and affective ToM measured using TASIT-S, but not RME-R. Age was not significantly associated with emotional empathy.
Conclusions:
This study contributes to the limited understanding of age-related associations of social cognitive performance throughout later life. This knowledge can inform future research examining the clinical utility of including social cognitive measures in neuropsychological screening and diagnostic tools for later-life neurological disorders.