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After World War II, many countries, including Nigeria, embraced Keynesian “welfarist” policies to stimulate economic growth and enhance the well-being of their citizens. However, in the late 1960s and early 1970s, a global economic crisis prompted a shift towards neoliberalism, leading to the commodification of social institutions and the implementation of policies such as privatization, trade liberalization and deregulation in Nigeria. This shift had a significant impact on Nigeria’s socio-legal economy, particularly in terms of property rights in company ownership. The article raises concerns about the structural injustice and growing inequality resulting from these neoliberal policies. It advocates for a legal framework that addresses these issues and proposes reconceptualizing private property rights in company ownership in Nigeria. This proposed framework aims to counter the dominance and power of property-owning elites and mitigate the structural injustice induced by neoliberal policies in Nigeria.
During the early twentieth century, Catalonia experienced a period of great cultural and musical development through the Noucentisme movement, which aimed to elevate its national culture to a symbol of high art. The xeremies (shawms) of the cobla ensemble, which played the sardana genre, were integrated into symphonic and chamber repertoire. This required the technical improvement of the tible (treble) and tenora (tenor) xeremies, but also encouraged the invention of new instruments in the shawm family. The barítona (baritone shawm) was premiered in 1930 by the Banda Municipal de Barcelona and represents a milestone in Catalan music in the tumultuous period before the Spanish Civil War.
Synthetic datasets, artificially generated to mimic real-world data while maintaining anonymization, have emerged as a promising technology in the financial sector, attracting support from regulators and market participants as a solution to data privacy and scarcity challenges limiting machine learning (ML) deployment. This article argues that synthetic data’s effects on financial markets depend critically on how these technologies are embedded within existing ML infrastructural ‘stacks’ rather than on their intrinsic properties. We identify three key tensions that will determine whether adoption proves beneficial or harmful: (1) data circulability versus opacity, particularly the ‘double opacity’ problem arising from stacked ML systems, (2) model-induced scattering versus model-induced herding in market participant behavior, and (3) flattening versus deepening of data platform power. These tensions directly correspond to core regulatory priorities around model risk management, systemic risk, and competition policy. Using financial audit as a case study, we demonstrate how these tensions interact in practice and propose governance frameworks, including a synthetic data labeling regime to preserve contextual information when datasets cross organizational boundaries.
This pilot cross-sectional study, conducted in two public hospitals in Malawi, assessed gestational diabetes mellitus (GDM) in pregnant women attending antenatal clinics and compared their dietary quality and food group consumption before and during pregnancy. The study targeted women aged 18 to 49 years within 24 to 28 weeks of gestation. GDM was diagnosed according to the International Association of Diabetes and Pregnancy Study Group criteria and assessed dietary quality before and during pregnancy using a 30-day qualitative food frequency questionnaire. We compared changes in dietary quality and specific food group mean scores using paired t-tests at p < 0.05. Of the 508 women enrolled, 22.7% were diagnosed with GDM. The overall diet quality significantly decreased during pregnancy compared to before; a similar trend was observed in women diagnosed with GDM compared to those without GDM (p < 0.0001). Among women with GDM, the mean score of the following food groups significantly (p < 0.05) decreased during pregnancy: cruciferous vegetables, deep orange vegetables and tubers, citrus fruits, deep orange fruits, other fruits, nuts and seeds, poultry, fish, low fat dairy, whole grains, and liquid oils and significantly (p < 0.05) increased in the following food groups; red meat, processed meat, sugar-sweetened beverages, sweets, sugary snacks and ice cream. In conclusion, GDM is prevalent in Malawian women enrolled in this study and is coupled with inadequate dietary quality, especially during pregnancy. Since dietary quality is pivotal to GDM management, more in-depth longitudinal dietary studies are needed to inform nutritional interventions to prevent and better manage GDM.
Child maltreatment increases the risk of emotional and behavioral problems, yet many children demonstrate resilience, functioning better than expected given their level of maltreatment exposure. Although resilience is a dynamic process shaped by children’s social support, including friendships, how different patterns of resilience and friendship support unfold together across development remains unclear. To better understand this process, we examined how patterns of emotional resilience, behavioral resilience, and friendship support co-develop across childhood and adolescence. We used group-based multi-trajectory modeling with data from the Avon Longitudinal Study of Parents and Children (N = 6, 518, 51% female) to identify distinct patterns of emotional and behavioral resilience (doing better-than-expected given their level of maltreatment exposure) and friendship support, across five timepoints from ages 6 to 17 years. We identified five trajectory groups. Nearly half the sample maintained high emotional and behavioral resilience and friendship support across development. While resilience trajectories varied, friendship support was generally high across groups. Most children followed trajectories of high resilience and perceived friendship support. Even among children with lower emotional and/or behavioral resilience trajectories, friendship support remained high, an encouraging finding. Future research should examine how children’s other relationships (e.g., with parents and siblings) unfold alongside resilience.
The main objective of this study was to analyse the changes of taxonomic, functional and phylogenetic diversities shown by bird assemblages at two contrasting vegetational types in Southern Mexico. Our main hypothesis was that we would find a higher diversity in Tropical Dry Forest (TDF) than in Oak Woodland (OW) due to a monotonic decrease in diversity with altitude. During eleven months, we surveyed both vegetation types to record bird species and abundances. We established points and simultaneously carried out 5-minutes count and soundscape recordings. We quantified our sampling effort by means of the sample coverage and calculated Hill numbers to express alpha and beta diversities. Contrary to our expectations, in terms of alpha taxonomic and functional diversities, the OW had consistently higher values than the TDF. After accounting for abundance data, we found a marked decrease in phylogenetic and taxonomic beta diversity, but an increase in functional diversity compared to the presence/absence matrix. The low beta phylogenetic diversity combined with the high beta functional diversity suggests that a small set of closely related species could have evolved in the dry slopes of the area, and by the action of niche differentiation developed different functional traits. The high functional beta diversity indicates a high complementarity between the avifaunas of each vegetation type, which is relevant in terms of conservation.
Flutter in lightweight airfoils under unsteady flows presents a critical challenge in aeroelastic stability and control. This study uncovers phase-dependent effects that drive the onset and suppression of flutter in a freely pitching airfoil at low Reynolds number. By introducing targeted impulsive stiffness perturbations, we identify critical phases that trigger instability. Using phase-sensitivity functions, energy-transfer metrics and dynamic mode decomposition, we show that flutter arises from phase lock-on between structural and fluid modes. Leveraging this insight, we design an energy-optimal, phase-based control strategy that applies transient heaving motions to disrupt synchronisation and arrest unstable growth. This minimal, time-localised control suppresses subharmonic amplification and restores stable periodic motion.
A modification of the semi-empirical theory of stratified turbulent flow, which includes an equation for the density fluctuations (the potential energy of turbulence), is applied to describe the effect of internal gravity waves (IWs) on the small-scale turbulence. After considering the periodic IWs, special attention is paid to the action of internal solitons, such as the classical Gardner solitons and a strongly nonlinear solitary wave regularly observed in the Oregon Bay of the USA. It is confirmed that the presence of potential energy allows the existence of finite turbulence at any Richardson number.
A critical step in systematic reviews involves the definition of a search strategy, with keywords and Boolean logic, to filter electronic databases. We hypothesize that it is possible to screen articles in electronic databases using large language models (LLMs) as an alternative to search equations. To investigate this matter, we compared two methods to identify randomized controlled trials (RCTs) in electronic databases: filtering databases using the Cochrane highly sensitive search and an assessment by an LLM.
We retrieved studies indexed in PubMed with a publication date between September 1 and September 30, 2024 using the sole keyword “diabetes.” We compared the performance of the Cochrane highly sensitive search and the assessment of all titles and abstracts extracted directly from the database by GPT-4o-mini to identify RCTs. Reference standard was the manual screening of retrieved articles by two independent reviewers.
The search retrieved 6377 records, of which 210 (3.5%) were primary reports of RCTs. The Cochrane highly sensitive search filtered 2197 records and missed one RCT (sensitivity 99.5%, 95% CI 97.4% to100%; specificity 67.8%, 95% CI 66.6% to 68.9%). Assessment of all titles and abstracts from the electronic database by GPT filtered 1080 records and included all 210 primary reports of RCTs (sensitivity 100%, 95% CI 98.3% to100%; specificity 85.9%, 95% CI 85.0% to 86.8%).
LLMs can screen all articles in electronic databases to identify RCTs as an alternative to the Cochrane highly sensitive search. This calls for the evaluation of LLMs as an alternative to rigid search strategies.
In this work, we discuss the challenges related to the preliminary investigation of high repetition rate (HRR) experiments in the field of high energy density (HED) physics, and we present the results of preparation experiments done at the Prague Asterix Laser System (PALS) laser facility conducted with the aim of defining the needed developments in target design, real-time diagnostics and data collection needed to meet HRR requirements. Although the PALS laser facility is not an HRR facility, it has served as a valuable test bed for advancing diagnostic techniques and refining target design in preparation for HRR experimental platforms. HRR operation will result in improved statistical errors of the experimental results, in particular for experiments related to equation of state studies in extreme conditions.
Against the status quo, this article argues for the right to renounce state citizenship while remaining a resident. To motivate this argument, it presents a dilemma: if long-term residents can choose not to naturalize, why cannot citizens renounce their status without leaving? This article rejects one way out of this dilemma—making citizenship mandatory for long-term residents—and proceeds to make the positive case for the right to renounce citizenship. It argues for the value of citizenship renunciation as an expressive political act, distinct from territorial exit, which allows individuals to sever political ties while maintaining social membership. This form of political exit enables citizens to express their detachment from the state without the costs of emigration. This article explores the implications of this proposal for democratic consent, legitimate authority, and collective citizen responsibility for state action, arguing that a right to renounce without emigration enhances autonomy and democratic legitimacy.
This research note introduces a new publicly available dataset identifying which federal candidates are out as LGBTQ2S+. The dataset comprises 4,201 candidates who ran in 2015, 2019 and 2021 for the five parties that won seats in the House of Commons. In this research note, we describe the replicable procedure we followed to identify out LGBTQ2S+ candidates, which involved systematic individual candidate searches. This procedure identified 176 LGBTQ2S+ candidates in total, which is more than in previous datasets. We illustrate how the data can be used by documenting how LGBTQ2S+ candidates changed over time relative to straight cisgender candidates. This dataset will allow researchers to examine a range of questions about LGBTQ2S+ representation as well as conduct intersectional analyses.
Electroconvulsive therapy (ECT) is one of the most effective treatments for depression, but worries about cognitive side effects remain. This retrospective study evaluated cognitive outcomes and the antidepressant efficacy of ECT in a real-life sample of patients with treatment-resistant uni- or bipolar depression.
Methods
We included 90 depressed inpatients aged 49 ± 13.8 (SD) years who underwent 10 ± 2.1 (SD) unilateral or bitemporal ECT treatments and completed an extensive pre- and post-treatment psychological test battery. The Hamilton Depression Rating Scale (HAMD) and the Mini-Mental State Examination (MMSE) were evaluated as main outcomes pre-/post-ECT treatment.
Results
There was no significant change in MMSE scores between pre-/post-treatment assessments (β = 0.10, 95% confidence interval [CI] [−0.44, 0.25], p = 0.58), indicating no negative effect on global cognition. A minority of patients (N = 3) experienced a reduction of ≥5 points in the MMSE. Most cognitive tests showed no difference; however, some domains revealed statistically significant improvements (visual learning and motoric reaction time), whereas one domain showed a significant decline (verbal learning). Higher age and higher stimulus doses predicted worse outcomes in some cognitive domains. While ECT significantly reduced depressive symptoms measured by HAMD (β = −5.51, 95% CI [−7.08, −3.94], p < 0.001), depressive symptoms were not associated with cognitive outcomes.
Conclusions
No major cognitive changes were observed. While test results indicated deterioration in verbal learning and improvement in visual learning and motoric reaction time, effect sizes were small, and other cognitive tests showed no significant changes. The main limitation is the absence of retrograde memory assessment.
A large literature has studied the effects of socialization under authoritarianism on political attitudes. In this research note, we extend this literature by demonstrating striking gender disparities in the post-transition persistence of these effects. We study the case of authoritarian indoctrination in the German Democratic Republic (GDR) using a regression kink design for causal identification. First, we draw on a unique survey fielded right before reunification to show that education under authoritarianism substantially reduced support for democratic capitalism and reunification with the West. In the second step, we triangulate multiple contemporary data sources to trace the persistence of these effects over time. More than two decades after the fall of the GDR, the attitudinal effects of authoritarian socialization persist only among men, but not women. Our results highlight considerable heterogeneity in the persistence of authoritarian legacies, raising critical questions about post-authoritarian ‘re-socialization’ and gendered adaptability.
Central venous catheter use is not standardised in paediatric cardiology, yet it is associated with additional morbidity. We aimed to characterise variation in central venous catheter use and complications across paediatric acute care cardiology units.
Methods:
This retrospective, multi-centre, and registry-based study examined all unique acute care cardiology encounters from February 2019 through September 2021 in the Paediatric Acute Care Cardiology Collaborative registry. Descriptive and comparative statistics were assessed for differences based on central venous catheter use. Multivariate logistic regression identified factors associated with increased line duration and use frequency.
Results:
About 35,379 encounters from 24 institutions were assessed. About one in five encounters had at least one central venous catheter (n = 7,524, 21.3%). Neonates and post-operative cardiothoracic surgery patients were more likely to have central venous catheters than not (28.9% of neonates with, versus 11.4% without; 58.4% of post-operative patients with, versus 35.7% without; p < 0.001). Most patients after STAT 4 procedures retained central venous access for over half of the acute care cardiology stay. Institutions with overall “low” central venous catheter utilisation rates (<20%) also used central venous access most often on STAT 4 patients (p < 0.0001). Complication rates for venous thrombus and central line-associated bloodstream infection were low (1.9% and 0.2%).
Conclusion:
There is variable utilisation of central venous catheters across participating acute care cardiology units, though overall they are common vascular access modalities. Acute care cardiology units use central venous catheters more often in neonates, those after cardiac surgery, and in their higher-risk patients (i.e. after STAT 4 procedures).
This study investigates the prevalence of coliform contamination in fresh milk and the occurrence of multidrug-resistant (MDR) bacteria within poultry environments on an integrated farm in Minna, Niger State. Bacterial isolates obtained from raw milk, poultry cloacal swabs, and intestinal swabs from commensal rats included Salmonella, Escherichia coli, and Klebsiella species. These isolates were screened for extended-spectrum beta-lactamase (ESBL) production and antimicrobial resistance (AMR) profiles. The results revealed a high level of bacterial contamination in milk samples, with significant associations between contamination levels and poor hygiene practices during milking and handling. Moreover, ESBL-producing bacteria displaying resistance to critically important antibiotics such as third-generation cephalosporins and fluoroquinolones were identified across both dairy and poultry sources. These findings highlight a pressing public health concern and emphasize the need for improved biosecurity, hygiene interventions and integrated AMR surveillance to safeguard food safety and reduce the spread of MDR pathogens in animal-source foods.
Two years on from the implementation of the Assisted Decision-Making (Capacity) Act (ADMCA) 2015, significant legal uncertainty persists in Ireland’s acute hospitals for the care of people who lack capacity to consent to treatment. Consultation-liaison psychiatrists must navigate a legal landscape where clear lacunae have emerged in the regulation of frequently encountered clinical scenarios. We identify three of these – eating disorders requiring refeeding, refusal of life-saving treatment, and unsafe discharges – where neither the ADMCA nor the Mental Health Act 2001 provide legal authority to intervene. In such cases, the Inherent Jurisdiction of the High Court has become the default mechanism for authorising treatment or deprivation of liberty, raising serious concerns about proportionality, clinical delays and uncertainty, cost, and consistency. We also consider a fourth category of patients who require immediate life-saving treatment, and the legal status of Advance Healthcare Directives in this context. Many of the patients who fall into these categories will have an established or suspected mental illness requiring the clinical input of a consultation-liaison psychiatry team.
We contrast Ireland’s evolving capacity legislation with developments in England and Wales. Reflecting on these comparisons, we consider the proposed Protection of Liberty Safeguards may provide some clarification but also contain potential risks of becoming unwieldy and bureaucratic and still fail to provide a workable statutory basis for authorising medical treatment in acute hospital settings. A proportionate, patient-centred, and clinically usable legal framework remains urgently needed.
This qualitative descriptive study aimed to explore dietary habits among healthcare workers during night shifts and to identify individual and environmental factors that influence their dietary behaviour during night shifts. Individual semi-structured interviews were conducted with twenty-five healthcare night female workers, which were recruited via email invitations from managers and posters placed in central workplaces at a university medical centre in the Netherlands. The interview protocol was developed following an integrated behaviour change model focusing on individual (I-Change model, i.e., awareness, motivation, intention, and ability) and environmental (Environmental Research framework for weight Gain prevention at environmental level (EnRG), i.e., physical, policy-related, economic, and sociocultural) factors. Inductive analyses were conducted to explore dietary habits, while deductive thematic analysis was applied to identify potential factors influencing dietary behaviour. Female healthcare workers in night shifts generally made poorer dietary choices during night shifts than during other shifts. Seven key themes were coded for dietary behaviour. Based on the domains of the integrated behaviour change model, four individual and five environmental key themes were established, within which 41 sub-themes were coded. Key individual factors included awareness (i.e., lack of knowledge about timing and type of consumption) and motivation (i.e., attitude and efficacy to eat healthy). Critical environmental factors included physical and sociocultural work environment, organisation of work, and lack of organisational policies. To conclude, future dietary interventions for healthcare night workers should target both individual behaviours and the workplace environment, with an emphasis on raising awareness and enhancing organisational policies to promote healthy dietary habits.