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Effectively controlling systems governed by partial differential equations (PDEs) is crucial in several fields of applied sciences and engineering. These systems usually yield significant challenges to conventional control schemes due to their nonlinear dynamics, partial observability, high-dimensionality once discretized, distributed nature, and the requirement for low-latency feedback control. Reinforcement learning (RL), particularly deep RL (DRL), has recently emerged as a promising control paradigm for such systems, demonstrating exceptional capabilities in managing high-dimensional, nonlinear dynamics. However, DRL faces challenges, including sample inefficiency, robustness issues, and an overall lack of interpretability. To address these challenges, we propose a data-efficient, interpretable, and scalable Dyna-style model-based RL framework specifically tailored for PDE control. Our approach integrates Sparse Identification of Nonlinear Dynamics with Control within an Autoencoder-based dimensionality reduction scheme for PDE states and actions (AE+SINDy-C). This combination enables fast rollouts with significantly fewer environment interactions while providing an interpretable latent space representation of the PDE dynamics, facilitating insight into the control process. We validate our method on two PDE problems describing fluid flows—namely, the 1D Burgers equation and 2D Navier–Stokes equations—comparing it against a model-free baseline. Our extensive analysis highlights improved sample efficiency, stability, and interpretability in controlling complex PDE systems.
How do Euroskeptic parties adjust their rhetoric when the European Union expands its fiscal and redistributive role? We address this question by examining the impact of the next-generation EU (NGEU) program on parliamentary debates in Italy, the largest beneficiary of EU recovery funds. Drawing on an original dataset of over 700 hand-coded parliamentary statements covering 30 debates in the Italian Chamber of Deputies (2018–2024), we show that the launch of NGEU coincided with a measurable increase in supportive rhetoric toward the EU, especially among parties with Euroskeptic profiles, a shift that is not solely attributable to changes in government status. Our findings suggest that EU-level redistributive policies can contribute to altering, at least temporarily, domestic party discourse in parliament, pointing to the domestic political relevance of fiscal integration
The cold, low carbon dioxide (CO2) conditions of the Pleistocene epoch fundamentally structured ecosystems, profoundly influencing the evolutionary trajectory of Homo sapiens and other large mammals. Although often considered uniquely stable, the Holocene is more usefully viewed as just another Pleistocene interglacial interval that was naturally trending towards a renewed glacial phase. However, rapid anthropogenic greenhouse gas emission rates have reversed this trajectory and might have now foreclosed the prospect of returning to cyclic glacial climates for millennia. A large set of flora and fauna has benefited from low CO2 conditions, which we define as low-CO2 dependents. By elevating atmospheric CO2 concentrations beyond levels seen for millions of years, we have accelerated global warming beyond the adaptive capacities of many species and ecosystems. African savannas and grasslands are particularly relevant in this context because this was the environment in which the human species evolved. These biomes have been previously maintained by fire and carbon scarcity but are now experiencing woody encroachment driven by rising CO2. The resultant global reforestation further threatens biodiversity adapted to open ecosystems, while rewilding initiatives must therefore pair prehistoric analogues with explicit climate-fitness tests that anticipate mid-century CO2 trajectories. Addressing these complex challenges requires both targeted local interventions and systemic policy reforms, grounded in a pragmatic recognition of the transient nature of the Holocene. Recognising the transience of any single baseline allows conservation and agriculture to plan for a dynamic, overshoot-prone future.
Can Hartian positivism adequately explain disagreements, among U.S. officials, about the correct method of statutory interpretation? Ronald Dworkin influentially argued it cannot. Dworkin maintained that (1) debates about the correct method of statutory interpretation are ‘theoretical’ disagreements; and (2) Hartian positivism cannot explain theoretical disagreements, except by positing implausible confusion or disingenuity on the part of legal officials. I show here that (1) is false. A disagreement about the correct method of statutory interpretation need not involve a theoretical disagreement of any kind. It may instead involve a purely ‘denotational’ disagreement among officials—i.e., a disagreement about the denotation of a concept appearing in a criterion of legal validity that all officials accept. I argue that, since the U.S. statutory interpretation debate plausibly is a purely denotational one, it does not pose the difficulties for Hartian positivism that Dworkin and other critics have supposed.
Theodicies attempt to explain why evil and suffering might exist in a world governed by an omnipotent, omniscient, and wholly good God. Some theodicies focus on pointing out benefits that suffering seems necessary for, though in many cases the benefits are primarily for someone other than the sufferer. Some philosophers find it morally objectionable for God to let one person suffer in order to benefit someone else, and this is thought to be a weakness of some otherwise promising theodicies. I discuss two moral concerns in this context: a mere-means-to-an-end concern and a concern about horrendous evils remaining undefeated. I argue that incorporating a doctrine of reincarnation may help some theodicies resolve both of these moral concerns, giving theodicists reason to turn towards such doctrines.
Non-suicidal self-injury (NSSI) displays an alarmingly high prevalence rate among university students, placing them at high risk for adverse long-term outcomes, including suicide.
Aims
This study aimed to achieve a better understanding of factors contributing to NSSI in university student populations by examining reasons for NSSI and histories of stressful events and coping strategies.
Method
A total of 185 university students with a lifetime history of NSSI were assessed for depressive symptoms and NSSI characteristics. They completed three questionnaires on NSSI reasons, stressful events and coping strategies during childhood and adolescence. Each questionnaire included an ‘others’ option combined with an open-ended response box. After descriptive analysis of the closed questions, these open-ended responses were qualitatively categorised and analysed as predictors of depression severity and NSSI continuation from adolescence into adulthood.
Results
Qualitative analysis identified eight, five and ten categories from the open-ended responses for NSSI reasons, stressful events and coping strategies, respectively, with substantial to almost perfect interrater reliability. Two qualitative reason categories, one stressful event category and two coping strategy categories significantly predicted depression severity (β = 0.21–0.23). Participants reporting events in the stressful events category ‘Traumatisation and experiences of violence’ were three times more likely to continue NSSI into adulthood (f2 = 0.07).
Conclusions
This study demonstrates the value of mixed-methods approaches. Stable qualitative categories highlight the need to capture individual variations in NSSI-related factors. It emphasises trauma-related stressors due to their influence on depression severity and persistence of NSSI into adulthood.
This article aims to explain how passive participles used as prenominal modifiers developed their eventive nature throughout the history of English. It is argued that prenominal participles first expressed stative result states in Old English (OE) and came to express perfect result states later on. The locus of required resultativity in participles was the inner aspect head in OE, while in Early Middle English (EME), it shifted to the outer aspect head. This shift was triggered by the loss of OE aspectual prefixes, which generally functioned to perfectivize or transitivize the verb by affecting its (internal) argument and assigning a change-of-state meaning to the verb. This shift rendered participial formation to be less constrained, as a result of which, it became possible for prenominal participles to express perfect resultative meanings, which in turn gave rise to their eventive meanings.
Regular finds of glassware at Roman sites provide a useful dataset not just for constructing glass typologies but for the comparative analysis of base-glass compositions. Here, the authors explore the form and chemical composition of 79 glass fragments from Khirbet al-Khalde, a strategically important site in southern Jordan that was integrated into a major Roman roadway, the Via Nova Traiana, in the early second century AD. Their findings challenge current models, identifying abundant pre-fourth-century Egyptian glassware in an area believed to be predominantly supplied by Syro-Palestine and providing evidence for continued activity at the site into the eighth century.
We propose a one-to-many matching estimator of the average treatment effect based on propensity scores estimated by isotonic regression. This approach is predicated on the assumption of monotonicity in the propensity score function, a condition that can be justified in many economic applications. We show that the nature of the isotonic estimator can help us to fix many problems of existing matching methods, including efficiency, choice of the number of matches, choice of tuning parameters, robustness to propensity score misspecification, and bootstrap validity. As a by-product, a uniformly consistent isotonic estimator is developed for our proposed matching method.
Psychotic-like experiences (PLEs) are considered a subclinical component of psychosis continuum. Studies indicate that PLEs arise from multimodal factors, yet research comprehensively examining these factors together remains scarce. Using a large youth sample, we present the first model that simultaneously examines multimodal factors related to PLEs. As a secondary aim, we evaluate the model’s ability to explain psychosis in an external validation cohort that included individuals experiencing psychosis.
Methods
After applying variable selection including generalized estimating equations, correlation filtering, Least Absolute Shrinkage and Selection Operator model to 741 variables (i.e., environmental factors, cognitive appraisals, clinical variables, cognitive functioning, and structural brain connectome measures), obtained PLEs predictors (N = 27) and covariates (i.e., age, sex, IQ) were included in the classification model based on Elastic Net algorithm for predicting high/low PLEs in 396 healthy participants aged 14–24 (Mage = 19.72 ± 2.5). We externally validated PLE-related predictors in a clinical sample comprising first-episode psychosis patients (n = 19), their siblings (n = 20), and healthy controls (n = 19).
Results
Eleven factors, including environmental and cognitive appraisals, along with 16 structural network properties spanning frontal, temporal, occipital, and parietal regions, were identified as important predictors of PLEs. The model’s performance was moderate in predicting low versus high PLEs (accuracy = 75%, AUC = 0.750). Specificity was high (84.2%) in distinguishing siblings from patients.
Conclusions
Multimodal features, including environmental burden, cognitive schemas, and brain network alterations, predict PLEs and partially generalize to clinical psychosis. These variables may reflect intermediate phenotypes across the psychosis spectrum, offering insights into both vulnerability and resilience.
Patients’ involvement in the decision-making process is essential for shared decision-making and optimal patient-centered care. However, when there are concerns about a patient’s cognition and judgmen, the complexity of providing patient-centered care increases. It is often necessary to evaluate patients’ decision-making capacity (DMC) to determine whether they are able to make a particular decision or whether to rely on their previously expressed wishes or the patient’s caregivers.
Methods
In this article, we present a case of an older adult with colon cancer who presented to the emergency room.
Results
We describe how multidisciplinary care can enhance the evaluation of DMC and improve quality of care for older patients with advanced cancer.
Significance of results
Multidisciplinary discussions and good communication skills are essential for navigating these complex situations, reducing potential harm and maximizimizing quality of life.
The present study deals with the electrophoresis of a non-polarizable droplet with irreversibly adsorbed ionic surfactants suspended in monovalent or multivalent electrolyte solutions. The impact of the non-uniform surface charge density, governed by the interfacial surfactant concentration, along with Marangoni, hydrodynamic and Maxwell stresses on droplet electrophoresis is analysed. At a large ionic concentration, the hydrodynamic steric interactions and correlations among finite-sized ions manifest. In this case the viscosity of the medium rises as the local volume fraction of the finite-sized ions is increased. The governing equations, incorporating these short-range effects, are solved numerically based on the regular linear perturbation analysis under a weak applied electric field consideration. We find that the electrophoretic velocity consistently decreases with an increase in the droplet-to-electrolyte viscosity ratio due to the Marangoni stress caused by inhomogeneous surfactant distribution. This monotonic relationship with droplet viscosity is absent for the case of constant surface charge density, where a low-viscosity droplet may exhibit a lower mobility than a high-viscosity droplet. In the presence of ionic surfactant, a continuous variation of mobility with surfactant concentration is found. For a monovalent electrolyte, mobility decreases significantly at an elevated ionic concentration due to the short-range effects described above. Reversal in mobility is observed in multivalent electrolytes due to the correlations among finite-sized ions, attributed to overscreening of surface charge and formation of a coion-rich layer within the electric double layer. In this case a toroidal vortex develops adjacent to the droplet and the reversed mobility enhances as the Marangoni number is increased. This mobility reversal is delayed for low-viscosity droplets.
The impact factor has become a defining feature of scientific journals. However, such reductionism can be toxic to science. As Cambridge University Press Quantitative Plant Biology celebrates its 5-year anniversary, and its first impact factor, this is an opportunity to set things straight. A call to value what a scientific journal is about: a community of scientists, a guarantee of rigour and quality, an invitation to explore the complexity of our world, a fair and ethical environment and an engaging, diverse and creative arena.
Despite high rates of intimate partner violence (IPV) among women, research on its mental health consequences, particularly PTSD in slum settings, remains scarce. This study assessed PTSD prevalence and determinants among slum-dwelling women in Bangladesh who experienced IPV during the COVID-19 pandemic. A cross-sectional study was conducted between July and October 2022 among 291 women from 5 urban slums in Dhaka, who reported IPV using the World Health Organisation questionnaire. Face-to-face interviews collected sociodemographic data, pandemic-related challenges, gender roles, health information and PTSD symptoms using the validated Post-Traumatic Stress Disorder Checklist-5. Logistic regression identified PTSD predictors. Most women were married before the age of 18 years (87.9%), unemployed (69.3%), had no formal schooling (38.6%) and lived in overcrowded households (38.6%). Over half of their husbands were daily wage earners (57.9%) and had a history of substance misuse (65.9%). PTSD prevalence was 21.16% and was higher among women with non-communicable diseases (adjusted odds ratio [AOR]: 3.29; 95% confidence interval [CI]: 1.6–6.7), concern about COVID-19 infection (AOR: 3.87; 95% CI: 1.12–13.22) and increased marital arguments (AOR: 3.00; 95% CI: 1.57–5.74). IPV in slum settings imposes a significant PTSD burden, highlighting the need for community-based mental health services to support marginalised women.
The incorporation of victim participation into the legal framework of the International Criminal Court (ICC) brought hope, to some, that the voices of victims would be elevated and heard more clearly in the ICC’s proceedings than they had been at previous international criminal tribunals, where they could participate only as witnesses. While research has emphasized the significant distinction to be drawn between the wide pool of victims of international crime and the far more restricted pool of ‘juridified victims’ who participate in international criminal proceedings, less attention has been drawn to the demographics of the juridified victim and the extent to which victim participation is shaped by factors such as age, gender, and disability. This article presents the results of a survey of practitioners and analysis of court documents which indicate that there are a wide range of barriers to the participation of certain groups of victims, which can result in their under-representation. It proposes measures that can be taken to foster a more inclusive victim participation scheme and calls for more rigorous monitoring and reporting on the demographics of victims that participate in ICC proceedings. It also sets out a case for greater inclusion rooted in the rights of victims, the requirements of the Court’s legal framework, the goals of the ICC and the promotion of victim agency and voice.
This article conceptually and empirically explores the Interwar Era’s variant of the ‘electoral authoritarian’ regime-type, relying on a unique recategorisation of all Central and Eastern European states to systematically classify non-democratic regimes between the two World Wars. Modern electoral authoritarian regimes are notable for combining the ‘standard model’ of electoralist structural features common to contemporary democracy with identifiably authoritarian political orders. Electoralist regimes of the period were distinct from those of today, with a greater emphasis on anti-political dominant parties, the inheritance of 19th century-style parliamentarism in terms of both institutional and political culture, and a reliance on unaccountable apex executives who nevertheless allowed authoritarian forms of multiparty politics. The article also introduces the era’s primary alternative for institutionalized regimes that do not fit the simple label of traditional dictatorship or electoral authoritarianism: the ‘institutional-hierarchical’ model. This characterizes innovations in corporatist-style economic and sectoral representation, as well as explicitly top-down, non-electoralist authoritarian constitutional structures and mobilized, single-party institutions. The article reviews all Interwar regimes in the region, providing alternative regime conceptualizations, exploratory classifications, and an illustrative case-study of Poland’s post-1926 Interwar style electoral authoritarian regime, highlighting both the survival of older electoralist models alongside a growing movement towards both more personalist and institutional-hierarchical formats by the 1930s.