Cet article examine les enjeux politiques et épistémiques de l’intégration des connaissances autochtones dans les systèmes de savoirs occidentaux, en y soulignant les résidus de l’impérialisme culturel. Adoptant une perspective épistémologique sociale et constructiviste, il nuance la vision majoritairement positive de cette intégration en la resituant dans un contexte de rapports de pouvoir historiques et structurels. Malgré ses intentions inclusives, l’intégration risque d’altérer profondément les savoirs autochtones en les soumettant aux cadres occidentaux, nécessitant ainsi une remise en question des structures qui façonnent la production et la validation des connaissances.

Understanding the interplay between adiposity and histopathological features of colorectal tumours is crucial for advancing strategies in disease management. We conducted a retrospective cohort study over an 8-year period (2007–2015), including patients who underwent surgical resection for colorectal cancer (CRC). Body composition was assessed via computed tomography (CT) at the level of the third lumbar vertebra, with visceral adipose tissue (VATd) and subcutaneous adipose tissue (SATd) radiodensities stratified into tertiles. Systemic inflammatory status was evaluated using the neutrophil-to-lymphocyte ratio (NLR). Logistic regression was employed to analyse the relationship between variables, using OR with 95 % CI. The Cox proportional hazards model assessed hazard ratios (HR) with 95 % CI. A total of 231 patients were included (48·9 % men, 51·1 % women), with 93·6 % in CRC stages II and III. Multivariate analyses demonstrated that CRC stages II and III (OR = 5·15, 95 % CI: 1·60, 16·62; OR = 5·16, 95 % CI: 1·59, 16·77) and low VATd (1st and 2nd tertiles; OR = 2·43, 95 % CI: 1·30, 4·53) were associated with the presence of desmoplasia. In the multivariate Cox analyses, only stage III disease (HR = 4·77, 95 % CI: 1·09, 20·89) and moderate to accentuated fibrous stroma (HR = 1·90, 95 % CI: 1·03, 3·46) were identified as predictors of reduced overall survival. These findings suggest that increased visceral adiposity may contribute to the development of a desmoplastic tumour microenvironment. Moreover, the presence of moderate to accentuated fibrous stroma is significantly associated with poorer long-term survival in patients with CRC.

Cet article présente une critique des conclusions auxquelles parvient C.Thi Nguyen (2020) dans le neuvième chapitre de Games: Agency As Art, qui met en garde contre les dangers de la ludification (gamification) de l’existence, c’est-à-dire le fait d’introduire des éléments fictifs de jeu dans la vie réelle. En mobilisant d’abord des recherches en neuropsychologie, afin de mettre en lumière les enjeux avec lesquels vivent les personnes neurodivergentes, je dénonce les présupposés capacitistes et l’ignorance neurotypique dont fait preuve Nguyen lorsqu’il aborde la ludification de la vie. Puis, je consolide ma critique en l’appuyant sur un point de vue différent, soit celui de le·a philosophe·sse Quill R. Kukla. Certes, son concept d’enchevêtrement (messiness) permet de remettre en question la vertu nguyenne de bon·ne joueur·euse. Enfin, j’atténue l’argument de Nguyen par rapport à la saisie de la valeur en avançant qu’il vise la mauvaise cible en accusant la ludification de l’existence en elle-même plutôt que les institutions néolibérales qui en instrumentalisent les atouts à des fins capitalistes et vicieuses.

Breeding management in laboratory rodents is challenging, particularly around parturition and the neonatal period, where cage disturbance is often avoided in an attempt to limit neonatal mortality. Nevertheless, cage-side observations and single daily checks frequently underestimate pup numbers born and miss parturition complications. Home Cage Monitoring (HCM) systems are gaining popularity in animal facilities, detecting critical events such as food availability and activity levels. Parturition is a complex event involving specific patterns of behaviour, activity and vocalisations. In this study, audio and video data were collected from parturition events of single-housed C57BL/6J females and breeding pairs housed in a prototype rack with integrated microphones. Vocalisations were detected during parturition in both housing conditions, with minimal vocalisations observed prior to parturition, except for ultrasonic sounds in pair-housed mice (Mus musculus). After parturition, all vocalisations gradually decreased. Despite limitations such as the need for post-event analysis and the focus on a single mouse strain, this study suggests that detecting vocalisations can be a promising basis for developing automated parturition detection. This highlights the potential of HCM systems for improving breeding management and welfare in laboratory rodent colonies.

Existing research has primarily examined coping strategies for dirty work while giving less attention to employees’ satisfaction. Much of this work has considered the phenomenon from an identity perspective, despite its underlying connections to job demands and resources. Drawing on the Job Demand-Resource (JD-R) model, this study investigates the relationship between dirty work and employee satisfaction, with emotional exhaustion as a mediating variable and self-consciousness as a moderator. Data collected from 234 participants in dirty work occupations with a 4-week time lag show that dirty work is positively associated with emotional exhaustion, which negatively impacts job, career, and life satisfaction. The findings further indicate that employees with higher self-consciousness report greater emotional exhaustion, while those with lower self-consciousness experience less emotional exhaustion. These results provide theoretical contributions to the dirty work literature and offer practical implications for mitigating emotional exhaustion in these roles.

Les ingénieurs en IA ont besoin de directives applicables pour l’implémentation de principes éthiques dans leurs solutions technologiques. Mais comment y arriver ? Dans cet article, nous prenons le cas du développement de l’intelligence artificielle explicable (XIA) comme point de départ. Sur le plan des mesures concrètes devant être intégrées à l’IA pour la rendre explicable, nous remettons en question l’approche universaliste. Nous proposons une méthodologie normative pour évaluer les mesures de la XIA adaptées à des contextes spécifiques. Cette approche intègre l’éthique dans le développement de l’IA, offrant ainsi une méthode pragmatique pour les ingénieurs, régulateurs et chercheurs en éthique.

This paper proposes a new surface fitting method based on double model comparison to solve the aspherical surface parameters, allowing for the simultaneous extraction of the surface deviation and the optimal surface fitting parameters for the radio antenna’s main reflector. This method employs the laser tracker to obtain the 3D coordinates of the points on the antenna surface, which can be expressed in terms of Zernike polynomials. Then compare the Zernike polynomial description with the ideal aspherical equation description to establish a discrepancy model in the optical design software. Finally, by optimizing this model, the optimal surface parameters can be obtained. The simulation results show that the method is suitable for high-precision fitting of aspherical surfaces with cone coefficient K in the range of [−4, 0.3], with the maximum deviation percentage of the radius of curvature at 0.036% and the cone coefficient at 0.14%. Experimental research is conducted on the 3.2 m sector sub-aperture spliced radio antenna; the fitted radius of curvature is 2012.3204 mm, the conic coefficient is −1.0476, and the Root Mean Square (RMS) is 0.6232 mm, confirming the adaptability of this method.

Milk fat is a crucial component for evaluating the production performance and nutritional value of goat milk. Previous research indicated that the composition of ruminal microbiota plays a significant role in regulating milk fat percentage in ruminants. Thus, this study aimed to identify key ruminal microorganisms and blood metabolites relevant to milk fat synthesis in dairy goats as a mean to explore their role in regulating milk fat synthesis. Sixty clinically healthy Xinong Saanen dairy goats at mid-lactation and of similar body weight, and similar milk yield were used in a feeding study for 15 days. Based on daily milk yield of dairy goats and the results of milk component determination on the 1st and 8th days, five goats with the highest milk fat content (H group) and five goats with the lowest milk fat content (L group) were selected for further analysis. Before the morning feeding on the 15th day of the experiment, samples of milk, blood and ruminal fluid were collected for analyses of components, volatile fatty acids, microbiota and metabolites. Results revealed that acetate content in the rumen of H group was greater compared with L group. H group had abundant beneficial bacteria including Ruminococcaceae_UCG-005, Saccharofermentans, Ruminococcaceae-UCG-002 and Prevotellaceae_UCG-3, which were important for plant cellulose and hemicellulose degradation and immune regulation. Metabolomics analysis revealed H group had greater relative concentrations of 4-acetamidobutanoic acid and azelaic acid in serum, and had lower relative concentrations of Arginyl-Alanine, SM(d18:1/12:0) and DL-Tryptophan. These altered metabolites are involved in the sphingolipid signaling pathway, arginine and proline metabolism. Overall, this study identified key ruminal microorganisms and serum metabolites associated with milk fat synthesis in dairy goats. These findings offer insights for enhancing the quality of goat milk and contribute to a better understanding of the regulatory mechanisms involved in milk fat synthesis in dairy goats.

In this study, the effects of wheat-based diets processed in a hammer mill with different sieve diameters (4000 (fine), 5000 (medium) and 6000 (coarse) µm) and enzyme addition (0 and 300 g/ton) on the performance, slaughtering characteristics, tibia properties, jejunum morphology and pancreatic enzyme secretion in broilers (1–42 days) were tested in a 3×2 factorial design. A total of 480 one-day-old chickens were randomly distributed into 6 treatment groups of 5 replicates, each containing 16 birds. The performance of broilers was not affected by particle size. Dietary enzyme supplementation improved body weight on the 1–10th day period but did not affect other performance parameters. Thigh and abdominal fat increased with fine particle size, breast weight increased with medium particle size and gizzard weight increased with coarse particle size. Enzyme addition decreased the carcass and gizzard weights. Tibia breaking strength decreased with fine particle size. Tibia wall thickness and ash increased with enzyme addition. Pancreatic enzyme secretions increased in the coarse group and with enzyme supplementation. Jejunum histomorphology worsened with coarse particle size, while enzyme inclusion improved histomorphology. The interactions affected feed consumption (25–42nd day), feed conversion ratio (11–24th day), breast weight, tibia breaking strength and ash, pancreas weight, lipase activity and villus parameters. These findings demonstrated that coarse grinding of wheat-based diets improved bone development and pancreatic enzyme activity without affecting performance while worsening jejunum morphology. Enzyme addition positively affected bone and digestive system development.

This article examines the 19th-century ‘antiquities rush’ – the frenzy of archaeological digging, scientific expeditions, and straightforward looting of artefacts in the broader Mediterranean – through the framework of international status competition. To do this, I first situate material culture at the foundation of international status-seeking and demonstrate the importance of cultural objects as status symbols for states. I then elaborate two logics of status-seeking that explain why states engaged in massive cultural extraction practices in the early 19th century. The first logic is that of cultural custodianship, where states pursued status as guardians of the cultural heritage of humankind. The second logic is a claim to cultural descendance, where states sought recognition as cultural heirs of classical civilisations. Cultural extraction, therefore, was critical in the establishment of the 19th-century international cultural hierarchy. Echoes of these arguments reverberate today in the competing claims of ownership and restitution of these antiquities. To illustrate these arguments, the article focuses on the international competition between France and Great Britain over the extraction of antiquities, examining in detail the removal of the Parthenon Marbles from Athens at the turn of the 19th century.

This study aimed to compare the clinical outcomes of using refrigerated versus pre-warmed media for preparing time-lapse dishes in in vitro fertilization (IVF). Patients undergoing their first IVF/ICSI cycle were divided into two groups. The control group used pre-warmed culture media, while the experimental group used refrigerated culture media. The osmotic pressure of the culture droplets in both groups was tested. No statistical differences were found between the two groups’ basic data. The proportion of air microbubbles affecting imaging significantly decreased (4.55% vs. 37.97%, P < 0.001) when using pre-warmed media. However, the blastocyst formation rate (56.62% vs. 49.70%, P = 0.046) and total high-quality embryo rate (22.26% vs. 17.06%, P = 0.047) were significantly higher in the refrigerated media group compared to the pre-warmed media group. The higher rate of high-quality embryos in the refrigerated media group might result in a higher single embryo transfer rate (45.10% vs. 18.52%, P = 0.020) and implantation rate (58.23% vs. 34.69%, P = 0.010). From day –1 to day 1, osmolality increased, with the P-3.5 group showing a significant elevation compared to the other three groups. After 5 days of incubation, the osmotic pressure of group R-4.0 was significantly lower than that of groups P-3.5, P-4.0 and P-3.5. In conclusion, refrigerated culture media dishes helped stabilize the osmotic pressure of the culture microenvironment and reduce water evaporation. The refrigerated group showed a higher rate of high-quality embryos and live births, although pre-warmed culture media effectively reduced the occurrence of air microbubbles that affect embryo imaging in the next day’s dishes.

The historiography of African American education has stressed the work of education professionals, tensions over curricula, and the desegregation of schools. Informal learning settings, while recognized as important educative spaces, have remained tangential to the broader narrative of the struggle for education. Thus, the influence of Black civic voluntary organizations is largely underexplored. In this essay I posit that instead of being on the margins, Black associations supplemented, guided, supported, and funded the education of African Americans through overlapping organizational networks that comprised autonomous counterpublic spaces. In these spaces, a wide variety of voluntary groups worked collaboratively to improve local public schools, to develop curricula centered on Black culture, and to provide educational opportunities for youth and adults. Recognizing that the history of African American education cannot be fully told without investigating informal spaces, this essay offers a roadmap for the investigation of Black civic voluntary organizations.

We revisit the time evolution of initially trapped Bose-Einstein condensates in the Gross-Pitaevskii regime. We show that the system continues to exhibit BEC once the trap has been released and that the dynamics of the condensate is described by the time-dependent Gross-Pitaevskii equation. Like the recent work [15], we obtain optimal bounds on the number of excitations orthogonal to the condensate state. In contrast to [15], however, whose main strategy consists of controlling the number of excitations with regard to a suitable fluctuation dynamics $t\mapsto e^{-B_t} e^{-iH_Nt}$ with renormalized generator, our proof is based on controlling renormalized excitation number operators directly with regards to the Schrödinger dynamics $t\mapsto e^{-iH_Nt}$.

Bactrocera dorsalis (Hendel) (Diptera: Tephritidae) is an invasive tropical pest that is currently expanding in its geographical range into temperate regions. This study examined the temporal and spatial dynamics of B. dorsalis along an altitudinal gradient in Mpumalanga Province, South Africa, in its southernmost adventive limit, which experiences a temperate climate with dry winters. Populations were monitored from October 2020 to October 2022 at three sites with altitudes ranging from 452 to 1 741 m above sea level. At each site, clusters of attractant-based traps (methyl eugenol and three-component Biolure) were set up and serviced at least monthly. We analysed the effects of climate, time of the year, altitude, and landscape on B. dorsalis abundance. Single population peaks of B. dorsalis were recorded from mid-summer to autumn in all sites, with higher prevalence at the low-altitude site. In the low- and mid-altitude sites, catches were recorded year-round, while at the high-altitude site, there were no catches for four to six months after onset of winter. Higher B. dorsalis catches were recorded as temperatures increased and precipitation decreased. Catches were higher in commercial orchards and home gardens compared to abandoned orchards. These findings provide valuable information for improving simulation models of B. dorsalis distribution and population growth that can be used to inform the management of this pest.

This article explores 2 key earthquake survival strategies: the widely endorsed “Drop, Cover, and Hold On” (DCH) method and the alternative fetal position within a survival triangle. While DCH provides mechanical protection from falling debris, its effectiveness in scenarios involving structural collapse and prolonged entrapment remains uncertain. Drawing on recent field data and thermodynamic considerations, this paper argues that the fetal position may offer survival advantages by minimizing heat loss and conserving metabolic energy—especially under cold conditions and delayed rescue. We emphasize the need for context-sensitive public safety guidance and further comparative research to inform adaptive earthquake preparedness protocols.