Menges (2022) seeks to identify the kind of blame that should be at issue in debates between skeptics and anti-skeptics about responsibility. Menges argues that such blame is constituted by responses that the target has a claim against, and by the blamer’s thought that they have forfeited this claim due to their bad action and state while engaged in that action. I identify a class of blame responses that Menges mistakenly excludes and offer an alternative, more general, account in which the distinctive feature of controversial blame isn’t claim forfeiture, but the defeat of reasons grounded in the target’s interests.

Orthoamphibole, clinoamphibole and magnetite are common minerals in altered rocks associated spatially with Palaeoproterozoic volcanogenic massive sulfide (VMS) deposits in Colorado, USA and metamorphosed to the amphibolite facies. These altered rocks are dominated by the assemblage orthoamphibole (anthophyllite/gedrite)–cordierite–magnetite±gahnite±sulfides. Magnetite also occurs in granitoids, banded iron formations, quartz garnetite, and in metallic mineralisation consisting of semi-massive pyrite, pyrrhotite, chalcopyrite, and sphalerite with subordinate galena, gahnite and magnetite; amphibole also occurs in amphibolite. The precursor to the anthophyllite/gedrite–cordierite assemblages was probably the assemblage quartz–chlorite formed from hydrothermal ore-bearing fluids (~250° to 400°C) associated with the formation of metallic minerals in the massive sulfide deposits.

Element–element variation diagrams for amphibole, magnetite and ilmenite based on LA-ICP-MS data and Principal Component Analysis (PCA) for orthoamphiboles and magnetite show a broad range of compositions which are primarily dependent upon the nature of the host rock associated spatially with the deposits. Although discrimination plots of Al/(Zn+Ca) vs Cu/(Si+Ca) and Sn/Ga vs Al/Co for magnetite do not indicate a VMS origin, the concentration of Al+Mn together with Ti+V and Sn vs Ti support a hydrothermal rather than a magmatic origin for magnetite. Principal Component Analyses also show that magnetite and orthoamphibole in metamorphosed altered rocks and sulfide zones have distinctive eigenvalues that allow them to be used as prospective pathfinders for VMS deposits in Colorado. This, in conjunction with the contents of Zn and Al in magnetite, Zn and Pb in amphibole, ilmenite and magnetite, the Cu content of orthoamphibole and ilmenite, and possibly the Ga and Sn concentrations of magnetite constitute effective exploration vectors.

We establish asymptotic formulas for all the eigenvalues of the linearization problem of the Neumann problem for the scalar field equation in a finite interval

\[ \begin{cases} \varepsilon^2u_{xx}-u+u^3=0, & 0< x<1,\\ u_x(0)=u_x(1)=0. \end{cases} \]

$\varepsilon ^2u_{xx}+u-u^3=0$

$-3$

$0$

$-3$

$0$

The Paisley Cave archeological site in the Northern Great Basin has provided a rich archaeological record from 13,000 to 6000 cal yr BP, including abundant mammalian coprolites preserved in a well-dated stratigraphy. Here we analyze and contrast pollen from within coprolites and pollen in associated sediments to examine vegetation history and assess whether coprolite pollen provides unique information with respect to the coprolite producer, such as the use of specific habitats, foods, or water sources. We found that the dissimilarity of pollen assemblages between coprolites and associated sediments was greater than the serial dissimilarity between stratigraphically adjacent samples within either group. Serial dissimilarity within types was not greater for coprolites than sediments, as would be expected if there were unique pollen signatures derived from the short period (1–2 days) represented by each coprolite. Compared with sediment pollen assemblages, the coprolites had higher abundances of lighter pollen types, and some individual samples were high in wetland taxa (especially Typha). Our results are consistent with coprolite pollen representing short time periods collected as a mammal moves on the landscape, whereas sediment pollen reflects longer time periods and more regional vegetation indicators.

Tests based on heteroskedasticity robust standard errors are an important technique in econometric practice. Choosing the right critical value, however, is not simple at all: conventional critical values based on asymptotics often lead to severe size distortions, and so do existing adjustments including the bootstrap. To avoid these issues, we suggest to use smallest size-controlling critical values, the generic existence of which we prove in this article for the commonly used test statistics. Furthermore, sufficient and often also necessary conditions for their existence are given that are easy to check. Granted their existence, these critical values are the canonical choice: larger critical values result in unnecessary power loss, whereas smaller critical values lead to overrejections under the null hypothesis, make spurious discoveries more likely, and thus are invalid. We suggest algorithms to numerically determine the proposed critical values and provide implementations in accompanying software. Finally, we numerically study the behavior of the proposed testing procedures, including their power properties.

Nordic Nutrition Recommendations recommend reducing red and processed meat and increasing fish consumption, but the impact of this replacement on mortality is understudied. This study investigated the replacement of red and processed meat with fish in relation to mortality. Of 83 304 women in the Norwegian Women and Cancer Study (NOWAC) study, 9420 died during a median of 21·0 years of follow-up. The hazard ratios (HR) for mortality were estimated using Cox proportional hazards regression with analyses stratified on red and processed meat intake due to non-linearity. Higher processed meat (> 30 g/d), red and processed meat (> 50 g/d), and fatty fish consumption were associated with higher mortality, while red meat and lean fish consumption were neutral or beneficial. Among women with higher processed meat intake (> 30 g/d), replacing 20 g/d with lean fish was associated with lower all-cause (HR 0·92, 95 % CI 0·89, 0·96), cancer (HR 0·92, 95 % CI 0·88, 0·97) and CVD mortality (HR 0·82, 95 % CI 0·74, 0·90), while replacing with fatty fish was associated with lower CVD mortality (HR 0·87, 95 % CI 0·77, 0·97), but not with all-cause or cancer mortality. Replacing processed meat with fish among women with lower processed meat intake (≤ 30 g/d) or replacing red meat with fish was not associated with mortality. Replacing processed meat with lean or fatty fish may lower the risk of premature deaths in Norwegian women, but only in women with high intake of processed meat. These findings suggest that interventions to reduce processed meat intake should target high consumers.

This paper deals with some Monge–Ampère type equations involving the gradient that are elliptic in the framework of convex functions. First, we show that such equations may be obtained by minimizing a suitable functional. Moreover, we investigate a P-function associated with the solution to a boundary value problem of our generalized Monge–Ampère equation in a bounded convex domain. It will be shown that this P-function attains its maximum value on the boundary of the underlying domain. Furthermore, we show that such a P-function is actually identically constant when the underlying domain is a ball. Therefore, our result provides a best possible maximum principles in the sense of L. E. Payne. Finally, in case of dimension 2, we prove that this P-function also attains its minimum value on the boundary of the underlying domain. As an application, we will show that the solvability of a Serrin’s type overdetermined problem for our generalized Monge–Ampère type equation forces the underlying domain to be a ball.

This article examines the relationship between public services and the urban middling sort in provincial England from 1550 to 1640 through comparative case-studies of the finance and management of waterworks, the creation of new skilled roles and the cultural import of water systems in Bristol, Chester and Ipswich. It argues that the middling sort were vital in establishing public services and that water provision centred not only on its value as a material and financial resource, but also as an expanding source of patronage and social capital that shaped and entrenched the emergence of middling groups in society.

1. (1) We show that it is possible to add $\kappa ^+$-Cohen subsets to $\kappa $ with a Prikry forcing over $\kappa $. This answers a question from [9].

2. (2) A strengthening of non-Galvin property is introduced. It is shown to be consistent using a single measurable cardinal which improves a previous result by S. Garti, S. Shelah, and the first author [5].

3. (3) A situation with Extender-based Prikry forcings is examined. This relates to a question of H. Woodin.

Recruiting persons with dementia for clinical trials can be challenging. Building on a guide initially developed to assist primary-care-based memory clinics in their efforts to support research, a key stakeholder working group meeting was held to develop a standardized research recruitment process, with input from patients, care partners, researchers, and clinicians. Discussions in this half-day facilitated meeting focused on the wishes and needs of patients and care partners, policy and procedures for researchers, information provided to patients, and considerations for memory clinics. Patients and care partners valued the opportunity to contribute to science and provided important insights on how to best facilitate recruitment. Discussions regarding proposed processes and procedures for research recruitment highlighted the need for a new, patient-driven approach. Accordingly, a key stakeholder co-designed “Memory Clinic Research Match” program was developed that has the potential to overcome existing barriers and to increase recruitment for dementia-related research.

In this paper, we analyze two types of refutations for Unit Two Variable Per Inequality (UTVPI) constraints. A UTVPI constraint is a linear inequality of the form: $a_{i}\cdot x_{i}+a_{j} \cdot x_{j} \le b_{k}$, where $a_{i},a_{j}\in \{0,1,-1\}$ and $b_{k} \in \mathbb{Z}$. A conjunction of such constraints is called a UTVPI constraint system (UCS) and can be represented in matrix form as: ${\bf A \cdot x \le b}$. UTVPI constraints are used in many domains including operations research and program verification. We focus on two variants of read-once refutation (ROR). An ROR is a refutation in which each constraint is used at most once. A literal-once refutation (LOR), a more restrictive form of ROR, is a refutation in which each literal ($x_i$ or $-x_i$) is used at most once. First, we examine the constraint-required read-once refutation (CROR) problem and the constraint-required literal-once refutation (CLOR) problem. In both of these problems, we are given a set of constraints that must be used in the refutation. RORs and LORs are incomplete since not every system of linear constraints is guaranteed to have such a refutation. This is still true even when we restrict ourselves to UCSs. In this paper, we provide NC reductions between the CROR and CLOR problems in UCSs and the minimum weight perfect matching problem. The reductions used in this paper assume a CREW PRAM model of parallel computation. As a result, the reductions establish that, from the perspective of parallel algorithms, the CROR and CLOR problems in UCSs are equivalent to matching. In particular, if an NC algorithm exists for either of these problems, then there is an NC algorithm for matching.

This article presents a reflective analysis of the role of public leadership within the context of crises, advocating for increased involvement of public health experts in crisis management. The study delves into the intricate dynamics that executives and board members exhibit when faced with crises. A primary focus of this research is the essential aspects that illuminate the engagement of public officials in the ongoing crisis, notably rapid decision-making and innovative thinking. The article underscores the paramount importance of leaders emphasizing values and mission while employing clear, meaningful, and empathetic communication. A comprehensive comprehension of public leadership emerges as a pivotal factor in crisis management, particularly when devising policy remedies for public health emergencies. The criticality of nurturing a new generation of healthcare CEOs and elevating the visibility of public health roles is underscored as an imperative for adeptly addressing the array of crises confronting us. This article broadens our insights into the multifaceted responsibilities of human resource management in both crisis response and recovery. Consequently, this endeavor facilitates the identification of evolving leadership roles essential for efficacious crisis management, fostering preparedness for prospective public health challenges.

The present study investigates bilinguals’ capacity to rapidly establish memory traces for novel word forms in a second language (L2), as a function of L2 linguistic proficiency. A group of Chinese-English bilinguals with various English proficiency levels were presented with a reading-aloud task, consisting of 16 pseudowords and 16 English words repeatedly presented across six training exposures. Behavioral and neurophysiological data were collected, and modulations in the word-length effect across repetitions were measured as an index of transition from sublexical to lexical involvement. Results revealed that higher L2 proficiency was associated with decreased word-length effect on novel words, reflected in both naming latencies and early N1 and P200 brain responses. In contrast, lower proficiency learners appeared to engage in effortful letter-to-sound decoding processes, with higher attentional allocation to the letter sequence and greater use of sublexical processing across exposures. Our findings highlight the need to tackle specific grapheme-to-phoneme skills for efficient learning of L2, particularly in populations where the L1 is nonalphabetic.

Maternal psychosocial stress is associated with delivery of both small- and large-for-gestational-age newborns. Prior studies have relied on methods that do not capture fat mass (FM) vs. fat-free mass (FFM). We aimed to assess the relationship of maternal psychosocial stress, using the Edinburgh Postnatal Depression Scale (EPDS) and Cohen’s Perceived Stress Scale (PSS), with newborn body composition. The sample included 604 mother/newborn pairs in the Healthy Start study. We used linear regression to examine associations of EPDS (>6.5 vs. ≤6.5) and PSS (>21 vs. ≤21) with newborn adiposity (FM and %FM measured by air displacement plethysmography [ADP], BMI-for-age, weight-for-length, and weight-for-age z-scores) and lean mass (FFM and length-for-age z-score). Average age of the women was 29.2 ± 6 y. Fifty-five percent of the women were white, 26.2% Hispanic, and 12.1% Black. Twenty-four percent of women had EPDS >6.5 and 18.1% had PSS >21. Mean ± SD birthweight was 3136 ± 437 g. After adjustment for confounders, EPDS >6.5 vs. ≤6.5 corresponded with 35.3 (95% CI: 6.6, 64.0) g lower offspring FM and 0.18 (−0.03, 0.39) units shorter length z-score. PSS was not associated with any neonatal outcomes. Maternal psychosocial stress is associated with delivery of shorter newborns with less FM.

Retinol binding protein (RBP) is used as a proxy for retinol in population-based assessments of vitamin A deficiency (VAD) for cost-effectiveness and feasibility. When the cut-off of < 0·7 μmol/l for retinol is applied to RBP to define VAD, an equivalence of the two biomarkers is assumed. Evidence suggests that the relationship between retinol and RBP is not 1:1, particularly in populations with a high burden of infection or inflammation. The goal of this analysis was to longitudinally evaluate the retinol:RBP ratio over 1 month of follow-up among fifty-two individuals exposed to norovirus (n 26 infected, n 26 uninfected), test whether inflammation (measured as α-1-acid glycoprotein (AGP) and C-reactive protein (CRP)) affects retinol, RBP and the ratio between the two and assess whether adjusting vitamin A biomarkers for AGP or CRP improves the equivalence of retinol and RBP. We found that the median molar ratio between retinol and RBP was the same among infected (0·68) and uninfected (0·68) individuals. AGP was associated with the ratio and RBP individually, controlling for CRP, and CRP was associated with both retinol and RBP individually, controlling for AGP over 1 month of follow-up. Adjusting for inflammation led to a slight increase in the ratio among infected individuals (0·71) but remained significantly different from the expected value of one. These findings highlight the need for updated recommendations from the WHO on a cut-off value for RBP and an appropriate method for measuring and adjusting for inflammation when using RBP in population assessments of VAD.

We discuss the role of weakly normal formulas in the theory of thorn forking, as part of a commentary on the paper [5]. We also give a counterexample to Corollary 4.2 from that paper, and in the process discuss “theories with selectors.”