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The International Commission on Radiological Protection (ICRP) Task Group 120 (TG120) is developing ICRP recommendations for radiological protection for a wide range of radiation accidents and malicious events, complementing those given in ICRP Publication 146 (2020) for large nuclear accidents. The scope includes accidents involving criticalities, operating faults, and fires and explosions in nuclear facilities, inadvertent damage to sealed radiation sources, as well as malicious events, such as sabotage of nuclear facilities or materials, use of radiological dispersal devices, the contamination of food and drinking water supplies, and the deployment of nuclear weapons. A template has been designed to collate relevant information on a wide range of case studies and hypothetical malicious scenarios to ensure that the recommendations developed are broadly applicable and comprehensive. For all scenarios, a graded approach to protection is being taken, accepting that specific guidance may be required for some distinctive aspects, for example, protection during times of armed conflict. This paper provides an overview of the scenarios and scope of the work of TG120, including some of the radiological and non-radiological impacts of radiation emergencies, along the response and recovery timeline.
We consider the two-dimensional nonlinear Schrödinger equation with point interaction and we establish a local well-posedness theory, including blow-up alternative and continuous dependence on the initial data in the energy space. We provide proof by employing Kato’s method along with Hardy inequalities with logarithmic correction. Moreover, we establish finite time blow-up for solutions with positive energy and infinite variance.
We give a complete classification of links up to clasp-pass moves, which coincides with Habiro’s $C_3$-equivalence. We also classify links up to band-pass and band-$\#$ moves, which are versions of the usual pass- and $\#$-move, respectively, where each pair of parallel strands belong to the same component. This recovers and generalizes widely a number of partial results in the study of these local moves. The proofs make use of clasper theory.
To assess whether universal masking during the COVID-19 pandemic reduced neonatal acquisition of S. aureus.
Study design:
We performed a retrospective cohort study of neonates admitted to a level three regional NICU for three years before and after implementation of universal masking for the COVID-19 pandemic. Multivariable proportional hazards regression models evaluated the effect of masking on time-to-acquisition of methicillin-resistant and methicillin-sensitive S. aureus (MRSA and MSSA) while adjusting for fixed and time-varying neonatal characteristics.
Results:
We analyzed 2,728 neonates, 1,446 pre-pandemic and 1,282 post-pandemic; 84.9% were inborn, with mean gestational age of 34 weeks and 6 days (SD = 4.2) and mean birthweight of 2,500 grams (SD = 975). The mean number of screening cultures per neonate was 3.07 (SD = 3.31). When adjusting for covariates, universal masking was associated with decreased acquisition of MRSA (hazard ratio =0.43 (95% CI: 0.19–0.99), p = 0.04) but not MSSA (HR = 1.27 (95% CI: 00.87–1.85), p = 0.21). Among covariates, airway devices and maternal S. aureus status were associated with S. aureus acquisition.
Conclusions:
Universal masking decreased the rate of NICU MRSA acquisition by 60% while MSSA acquisition was unchanged. Masking may reduce MRSA spread via colonized healthcare personnel while MSSA may be more likely to be acquired from parental skin-to-skin contact and was thus unaffected by masking.
Mood disorders are among the leading causes of disease burden worldwide, with 20–70% of affected individuals experiencing comorbid premenstrual disorders. This systematic review and meta-analysis investigated the comorbidity of premenstrual dysphoric disorder (PMDD) or premenstrual syndrome (PMS) with non-reproductive mood disorders.
Aims
We aimed to determine the pooled prevalence of PMDD/PMS with adult mood disorders, assess the impact of comorbidity on clinical course and summarise the associated neurobiological findings.
Method
Eligible studies were identified through Embase, MEDLINE and APA PsycINFO from inception to 22 January 2024 (PROSPERO, no. CRD42021246796). Studies on women (‘females‘) with diagnoses of PMDD/PMS and mood disorders were included. Risk of bias was assessed using National Institutes of Health quality assessment tools. A random-effects, pooled-prevalence meta-analysis was conducted using the Comprehensive Meta-Analysis software, categorising diagnostic sampling strategies as follows: mood disorders diagnosed first, PMDD/PMS diagnosed first or concurrent diagnoses. A narrative synthesis explored secondary outcomes, including illness course and biomarkers.
Results
A total of 39 studies were included, with 36 of these (n = 3646) contributing to the meta-analysis. Seven studies focused on bipolar disorders, 18 on unipolar depressive disorders and 14 on mixed samples of bipolar and unipolar disorders. Random-effects pooled-prevalence meta-analyses showed consistently high comorbidity rates between PMDD/PMS and mood disorders, ranging from 42% (95% CI: 30%, 55%) to 49% (95% CI: 38%, 60%) across sampling strategies. Risk of bias varied, with methodological heterogeneity noted.
Conclusions
This review underscores high comorbidity rates between PMDD/PMS and mood disorders, regardless of sampling strategy, and highlights the need for research into clinical and neurobiological characteristics specific to this comorbidity. Limitations include study heterogeneity, reliance on cross-sectional designs and provisional PMDD/PMS diagnoses. Future research should address these gaps to inform diagnostic and therapeutic advancements tailored to this population.
We explore an overlooked phenomenon in mortgage markets: repayment of underwater mortgages. Using a sample of mortgages terminated between 2007 and 2016, we show that such repayment indeed occurs, and that it is affected by the same factors commonly used in studies of default: the magnitude of home equity and the borrower’s credit score, which captures default cost as well as liquidity. A novel insight is that underwater repayers, unlike most defaulters, are not liquidity constrained, providing a much cleaner environment to study default costs. We estimate lower bounds on these costs. Our results indicate that default costs are substantial.
Perinatal women were particularly impacted during the pandemic, with documented consequences for both mothers’ and infants’ well-being. This study investigated the longitudinal relationships between COVID-19-related experiences during the peripartum and women’s depression and anxiety symptoms at long-term follow-up. We explored the moderating role of long COVID for the first time, along with perceived partner support and maternal self-efficacy. A sample of 190 US perinatal women completed a survey from May 21, 2020, to September 15, 2021 (T1), and again between December 14, 2022, and February 14, 2024 (T2). The survey assessed COVID-19-related experiences, mental health, long COVID, maternal self-efficacy, partner support, and life events. Anxiety was associated with both long COVID and decreased partner support, and both depression and anxiety were linked to lower self-efficacy. A larger number of COVID-19-related experiences during the peripartum period was associated with higher levels of later depression and anxiety symptoms. Long COVID exacerbated these links, while partner support buffered them. Maternal self-efficacy dampened the association between COVID-19-related experiences and subsequent depression, but not anxiety. Findings suggest that COVID-19 has lasting effects on perinatal women’s mental health, with partner support and maternal self-efficacy acting as resilience factors, highlighting the potential benefit of targeted interventions to enhance these modifiable factors.
Several hypotheses are employed to describe the fluctuating motions within nozzles and to analytically predict combustion noise generation mechanisms. One of these assumptions is that of a calorifically perfect gas mixture, where $c_p$ is constant. Nonetheless, a realistic flow rather encompasses heat capacities $c_p$ that vary with temperature, i.e. $c_p = c_p(T)$, such that the mixture is called thermally perfect. The influence of the mixture assumptions on noise generation mechanisms is re-examined in this paper. To do so, the quasi one-dimensional Euler equations for multi-species, isentropic and non-reactive flow are considered within the nozzle. Their linearisation yields a new prediction model in addition to showing a new entropy-to-entropy coupling mechanism. Relying on either the assumption of low frequencies or the Magnus’ expansion methodology, two analytical solutions are derived and studied. Validation of these two prediction models is then provided relying on unsteady simulations of axisymmetric nozzles with superimposed incident waves. To generalise previous results, parametric studies are performed considering various nozzle flow geometries. Variations of up to $10\,\,\%$ are exhibited in a choked flow nozzle between the two mixtures, especially for the indirect entropy noise and the entropy-to-entropy transmission moduli.
Although many contemporary theologians and philosophers of religion distinguish between ‘idolatry’ in a general sense and ‘conceptual idolatry’ as a distinct error, close attention to theorists of idolatry shows that ‘conceptual idolatry’ should not be considered distinct from idolatry proper. After discussing the relation between concepts and idolatry in key thinkers from the phenomenological and grammatical traditions, this article discusses analytic attempts to understand idolatry, showing how each falls short.
Ultimately, attention to the category of ‘conceptual idolatry’ shows the deficiencies present in contemporary framings of idolatry simpliciter. This article concludes with a proposal for a new framework by which to understand the dispute about idolatry: turning away from the question of whether we are worshipping the right God, towards the question of how God might (and might not) become apt to human thought and speech.
We propose a novel micro-level Cox model for incurred but not reported (IBNR) claims count based on hidden Markov models. Initially formulated as a continuous-time model, it addresses the complexity of incorporating temporal dependencies and policyholder risk attributes. However, the continuous-time model faces significant challenges in maximizing the likelihood and fitting right-truncated reporting delays. To overcome these issues, we introduce two discrete-time versions: one incorporating unsystematic randomness in reporting delays through a Dirichlet distribution and one without. We provide the EM algorithm for parameter estimation for all three models and apply them to an auto-insurance dataset to estimate IBNR claim counts. Our results show that while all models perform well, the discrete-time versions demonstrate superior performance by jointly modeling delay and frequency, with the Dirichlet-based model capturing additional variability in reporting delays. This approach enhances the accuracy and reliability of IBNR reserving, offering a flexible framework adaptable to different levels of granularity within an insurance portfolio.
This paper studies public opinion towards the introduction of a universal basic income in the case of Germany. Using novel data from a vignette survey experiment conducted in the summer of 2022, we analyse to what extent variations in the policy design characteristics of a hypothetical basic income scheme affect levels of support. We find that support for basic income strongly depends on these characteristics, with support being highest for schemes that are relatively generous, paid to citizens and long-term residents, paid to individuals rather than households, unconditional and financed with taxing the rich. In a further step, we explore interaction effects between vignette dimensions and respondent characteristics, finding significant heterogenous treatment effects in the cases of income, age and ideology.
In response to the prevailing trend of an aging society and the increasing requirements of rehabilitation, this paper presents an approach involving brain-machine interaction (BMI) for a single-degree-of-freedom (1-DOF) sit-to-stand transfer robot. Based on a 1-DOF rehabilitation robot, three experiment paradigms involving motor imagery (MI), action observation of motor imagery (AO-MI) and motor execution are designed using both electroencephalography (EEG) and electromyography (EMG). To enhance motion intention recognition accuracy, a Gumbel-ResNet-KANs decoding model is established. The Gumbel-ResNet-KANs model integrates the Gumbel-Softmax method with the ResNet-KANs network module and demonstrates strong decoding capability, as demonstrated by comparative tests in this paper. To validate the effect of robotic assistance, EEG and EMG coherence are analyzed to assess the impact of robotic assistance on rehabilitation from a neuromuscular perspective in both assisted and unassisted conditions. We assessed the effect of robotics on rehabilitation from an emotional perspective by analyzing the difference between the differential entropy of the right and left brain. The proposed study also reveals that the movement-related cortical potentials in AO-MI are beneficial for promoting the performance of BMI in sit-to-stand training, which provides a possible approach for the development of new types of robots for lower limb rehabilitation.
There are multiple equilibrium points in the launching and unfolding process of the multi-body aircraft. Different equilibrium points exhibit different stability characteristics and change with parameters such as connection method. The changes in stability characteristics can also lead to the inability of multi-body aircraft to achieve stable deployment. To solve these problems, the dynamic stability of multi-body aircraft during falling is analysed based on bifurcation theory in this paper. In this paper, Lagrange multiplier method is used to establish the multi-body dynamics model of the multi-body aircraft, and the curly spring torque model is added. In order to consider the coupling effect between the wings and the influence of the relative motion between the flight units on the aerodynamic force, the reference angle-of-attack, the reference sideslip angle, the relative attitude angle and the relative attitude angular velocity between the flight units were introduced as new variables to establish the aerodynamic model of the multi-body aircraft. Based on the equilibrium equations, the equilibrium curve of the two-body aircraft is obtained by using the joint stiffness coefficient as the continuous variable parameter. The stability of the equilibrium point domain on each equilibrium curve was analysed by using linearised theory. The dynamic characteristics of the launching and unfolding process of the two-body aircraft were analysed using bifurcation theory, and the stable domain was obtained regarding the initial folding angle and connection stiffness coefficient. The influence of initial folding angle and connection stiffness coefficient on the dynamic characteristics of the launching and unfolding process and the meaning of the stability domain were analysed through numerical simulation calculations. Finally, the correctness of the analysis conclusion was verified through experiments on the two-body aircraft, accumulating the technical foundation for subsequent research on high-altitude deployment.
Coarctation of the aorta is characterised by narrowing of the descending aorta and is a rare cause of secondary hypertension in children and young adults. The aortic stenosis lesion is in a special location with severe consequences, and long-term survival is very low, with high rates of disability and mortality, and can be challenging to detect due to its few clinical manifestations. We report a case of a young patient with atrial fibrillation, renal infarction, and acute cerebral infarction, which are consequences of untreated hypertension due to coarctation of the aorta. The purpose of this report is to emphasize the importance of early diagnosis and management of coarctation of the aorta as a cause of secondary hypertension in children and young adults.
A museum should be a place where cultures, dialogue, and social relations are enhanced. Given the renewed public interest in the topic, the author poses the question: Is there a need and a possibility to decolonize ethnographic museums? Should we have common and shared practices? In an attempt to eliminate colonial vestiges in museums, an analysis of literature and practices leads the author to analyze five European ethnographic museums in order to understand their merits and shortcomings. The subjectivity of these institutions and the diversity with which colonization can be presented makes the proposal of a single generalized solution not preferable. An objective analysis, based on actions and variables, drives the author to determine, however, that in order to revitalize museum practices, there is a need to create a sharable framework. The design of minimum standards can help museums set clear and measurable goals to achieve a higher level of decolonization.
The physical fidelity of turbulence models can benefit from a partial resolution of fluctuations, but doing so often comes with an increase in computational cost. To explore this trade-off in the context of wall-bounded flows, this paper introduces a framework for turbulence-resolving integral simulations (TRIS) with the goal of efficiently resolving the largest motions using a two-dimensional, three-component representation of the flow defined by instantaneous wall-normal integrals of velocity and pressure. Self-sustaining turbulence with qualitatively realistic large-scale structures is demonstrated for TRIS on an open-channel (half-channel) flow configuration using moment-of-momentum integral equations derived from Navier–Stokes with relatively simple closure approximations. Evidence from direct numerical simulations (DNS) suggests that TRIS can theoretically resolve $35\,\%{-}40\,\%$ of the turbulent skin friction enhancement for friction Reynolds numbers between $180$ and $5200$, without a noticeable decrease or increase as a function of Reynolds number. The current implementation of TRIS can match this resolution while simulating one flow through time in ${\sim}1$ minute on a single processor, even for very large Reynolds numbers. The framework facilitates a detailed apples-to-apples comparison of predicted statistics against data from DNS. Comparisons at friction Reynolds numbers of $395$ and $590$ show that TRIS generates a relatively accurate representation of the flow, while highlighting discrepancies that demonstrate a need for improving the closure models. The present results for open-channel flow represent a proof of concept for TRIS as a new approach for wall-bounded turbulence modelling, motivating extension to more general flow configurations such as boundary layers on immersed objects.