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Inspired by Bhatt–Scholze [BS22], in this article, we introduce prismatic cohomology for rigid analytic spaces with l.c.i. singularities, with coefficients over Fontaine’s de Rham period ring ${\mathrm {B_{dR}^+}}$.
This note argues that imitation of Ausonius’ Cento nuptialis in the Peruigilium Veneris establishes 374 c.e. as the terminus post quem for the Peruigilium Veneris. The note enlarges on the argument of Danuta Shanzer, who identified debts to Ausonius in the Peruigilium Veneris and dated the latter poem accordingly: the approach is to locate evidence for Ausonian imitation that Shanzer missed, and thus to reinforce and confirm her position. While the note does not propose a poet for the Peruigilium Veneris, it shows that certain figures to whom the work is commonly attributed, notably Florus and Tiberianus, cannot be its author.
Let X be an uncountable Polish space and let $\mathcal {I}$ be an ideal on $\omega $. A point $\eta \in X$ is an $\mathcal {I}$-limit point of a sequence $(x_n)$ taking values in X if there exists a subsequence $(x_{k_n})$ convergent to $\eta $ such that the set of indexes $\{k_n: n \in \omega \}\notin \mathcal {I}$. Denote by $\mathscr {L}(\mathcal {I})$ the family of subsets $S\subseteq X$ such that S is the set of $\mathcal {I}$-limit points of some sequence taking values in X or S is empty. In this article, we study the relationships between the topological complexity of ideals $\mathcal {I}$, their combinatorial properties, and the families of sets $\mathscr {L}(\mathcal {I})$ which can be attained. On the positive side, we provide several purely combinatorial (not depending on the space X) characterizations of ideals $\mathcal {I}$ for the inclusions and the equalities between $\mathscr {L}(\mathcal {I})$ and the Borel classes $\Pi ^0_1$, $\Sigma ^0_2$, and $\Pi ^0_3$. As a consequence, we prove that if $\mathcal {I}$ is a $\Pi ^0_4$ ideal then exactly one of the following cases holds: $\mathscr {L}(\mathcal {I})=\Pi ^0_1$ or $\mathscr {L}(\mathcal {I})=\Sigma ^0_2$ or $\mathscr {L}(\mathcal {I})=\Sigma ^1_1$ (however we do not have an example of a $\Pi ^0_4$ ideal with $\mathscr {L}(\mathcal {I})=\Sigma ^1_1$). In addition, we provide an explicit example of a coanalytic ideal $\mathcal {I}$ for which $\mathscr {L}(\mathcal {I})=\Sigma ^1_1$. On the negative side, since $\mathscr {L}(\mathcal {I})$ contains all singletons, it is immediate that there are no ideals $\mathcal {I}$ such that $\mathscr {L}(\mathcal {I})=\Sigma ^0_1$. On the same direction, we show that there are no ideals $\mathcal {I}$ such that $\mathscr {L}(\mathcal {I})=\Pi ^0_2$ or $\mathscr {L}(\mathcal {I})=\Sigma ^0_3$. In fact, for instance, if $\mathcal {I}$ is a Borel ideal and $\mathscr {L}(\mathcal {I})$ contains a non $\Sigma ^0_2$ set, then it contains all $\Pi ^0_3$ sets. We conclude with several open questions.
Intergenerational programs can support social connectedness, and an important element is engaging in activities together, known as ‘co-occupation’. To address gaps in the literature, we explored how older adults and university students living together in a retirement home enacted co-occupations, the factors that shaped the co-occupations, and how the co-occupations affected intergenerational relationship-building and connections. We conducted a focused ethnography using a constructivist-interpretivist paradigm, interviews with university students and older adults, and on-site observations. We analysed data using reflexive thematic analysis. Co-occupations were critical in creating connections and mutually beneficial intergenerational relationships. Participants often transformed co-occupations to promote interactions. Important features of intergenerational housing appear to be access to co-occupations that are structured and unstructured, flexibility to modify co-occupations, and physical spaces that promote co-occupation. This research illustrates how co-occupation within intergenerational housing programs can support connection and relationship-building. Findings can be applied within intergenerational housing and other intergenerational programs.
This article confronts the idea—especially widespread in the field of political philosophy, amongst Italian philosophers associated with feminism of difference, and in general narratives of 1970s Italian feminism—that Carla Lonzi was an anticipator of the Italian thought of sexual difference. Contra seminal texts like Non credere di avere dei diritti (1987) and scholars affiliated with the Libreria delle Donne di Milano and the Diotima philosophical collective, I illustrate how Lonzi was extraneous to the theoretical foundations and practices of “femminismo della differenza.” Notions of the symbolic mother, practices of disparity and ‘entrustment’, concerns with bringing into existence a female symbolic order—which would ground the development of the thought of sexual difference—were either absent in Lonzi’s writings or contested by her. While Lonzi’s work has increasingly been used to advance essentialist, gender-critical arguments by philosophers close to feminism of difference (for whom her work seemingly provides support against the very existence of non-binary, queer, and trans lives), I show how her approach to sexual difference departed significantly from such interpretations and can rather be more convincingly understood through Simone de Beauvoir.
We analysed cardiac MRI and catheterisation variables during pre-Fontan evaluations for associations with major adverse cardiac events including Fontan takedown, mechanical circulatory support, heart transplantation, or death.
Methods:
In this single-centre retrospective study, we gathered pre-operative MRI and catheterisation data for all patients who underwent Fontan operation at Children’s Medical Center, Dallas, from April 2017 to November 2022. Patients were grouped according to the presence or absence of adverse events, and MRI and catheterisation parameters were compared between groups. We used the Mann–Whitney U Test for non-parametric data, Student’s T-test for parametric continuous variables, and Fisher’s Exact Test for categorical variables.
Results:
Of the 119 combined evaluations, 81 proceeded with Fontan palliation. Adverse events were recorded in 10% of patients (n = 8). One had a Fontan takedown, one underwent transplant, one required mechanical circulatory support, and five died in a median 21-month follow-up. Factors significantly associated with adverse events included heterotaxy syndrome (p = 0.04), higher combined pulmonary vascular resistance (p = 0.03), and moderate-severe (≥30%) atrioventricular valve regurgitation (p = 0.046). While combined pulmonary vascular resistance calculated from both catheterisation and MRI data predicted outcome, pulmonary vascular resistance calculated using data solely from catheterisation showed no discriminative ability.
Conclusions:
Post-Fontan major adverse cardiac events were associated with heterotaxy syndrome, higher combined pulmonary vascular resistance, and moderate-severe atrioventricular valve regurgitation identified on pre-Fontan MRI and catheterisation. Combined pulmonary vascular resistance using transpulmonary gradient from catheterisation data and effective pulmonary blood flow from MRI data may help predict outcome.
This essay memorializes William E. Leuchtenburg (1922–2025), who over the course of his long, distinguished career made numerous significant contributions to policy history, presidential history, and the history profession in general.
Under current Dutch regulations, accurate assessment of the amount of P secreted in milk is essential, as it determines manure P output. The two main aims were: 1) to predict P content in bovine milk using a broad range of predictor variables, and 2) to obtain predicted milk P contents representative of the Dutch dairy cow population. A secondary objective was to evaluate seasonal variation in milk P content. Weekly bulk milk samples (week 14 in 2017 up until week 13 in 2018) were collected from 14 dairy plants located across the Netherlands and pooled per week as representative samples of Dutch bovine milk. Milk samples were analysed for macronutrients and mineral contents. The mean P content of milk was 101.2 mg/100 g, and significant seasonal variation was observed, with the highest values found during winter and the lowest during summer. The contents of fat, protein, casein, Ca, Mg and Mn in milk were found to be highly correlated with the milk P content. The preferred multiple regression equation to predict the milk P content (mg/100 g) included the predictor variables milk fat (g/100 g), Ca (mg/100 g) and K (mg/100 g), viz. milk P content = – 58.6 (±14.09) + 0.28 (±0.104) × Ca + 11.46 (±2.559) × fat + 0.48 (±0.094) × K, and explained 80% of the variation (R2adj) in milk P content. The contribution of milk K content to explain variation in milk P content cannot be physiologically explained.
A series of experiments comparing winter wheat, rye and triticale varieties andbreeding lines was carried out during 1981-3.
In two experiments on good arable soils and in the absence of inter-plotcompetition, lodging and differential disease incidence, the greatest grain yields were obtained from the semi-dwarf winter wheat variety Norman. The best triticales gave yields similar to those of the winter wheat varieties which lacked the semi-dwarfing gene, though they were somewhat taller than the wheat. Total above-ground dry matter (biomass) yields were generally similar for the best wheat and triticale varieties. A triticale breeding line with the Rht3, dwarfing gene was considerably shorter than the others, all of which had the Rht1, allele, but it had lower grain yield and biomass than either theRht1, triticale or the winter wheat variety of comparable height.
In a third experiment on a loamy sand, the triticales gave 16% greater grain and 23% greater biomass yields than the three wheat varieties tested. However, as disease control in the wheat was not fully effective in this experiment, the yield advantage of the triticales may have been exaggerated.
In one of the experiments, in which different rates of fertilizer nitrogen were given, the rye and triticales were as responsive to the fertilizer as were the wheat varieties.
It is concluded that, given comparable selection for high yield, triticale varieties could be produced in the U.K. which would be capable of yielding as much as the highest yielding varieties of winter wheat. The triticales tested grow more rapidly during the winter and flowered earlier than the wheat varieties. Provided that improved triticales retained these characteristics they would be more likely than winter wheat to escape the effects of summer drought, and so be more suitable for light soils.
This note addresses a grammatical objection, first raised by Torstrik, to the transmitted text of Aristotle’s De anima 3.7, namely that the text contains at 431a4–7 a μέν without a corresponding δέ (or another adversative particle). Rejecting Corcilius’s suggestion that this is a μέν solitarium, the note shows that modest repunctuation reveals a responding δέ and makes better sense of this part of the text.
Four new species of Poecilosclerida (Porifera, Demospongiae) assigned to the genera Latrunculia and Iophon are described from South Africa and Namibia, located in the Namaqua ecoregion. The Porifera occurring along the continental shelf within this ecoregion are relatively well-known, with 76 species formally described in previous literature. Of these, 35 species belong to the Order Poecilosclerida. Additionally, Latrunculia (Aciculatrunculia) biformis is reported from the continental shelf on the west coast of South Africa, extending its range further northwards into the South Atlantic. DNA barcoding and molecular phylogenetic analyses were employed to ensure accurate taxonomic assignment and designation of new species.
Avoidant/restrictive food intake disorder (ARFID) is a condition characterised by an avoidance or restriction of food intake that has a detrimental impact on physical health, psychosocial functioning or both. ARFID has now been classified in ICD-11, alongside DSM-5; however, challenges remain for healthcare professionals in recognising ARFID in young people and identifying best practice for managing their care. This educational article aims to provide an update on the epidemiology and clinical presentation of ARFID in children and young people, with a particular focus on co-occurring neurodevelopmental conditions and psychiatric disorders. A multidisciplinary approach to assessment and management is key, working closely with the young person and the system around them. Physical and psychosocial risk assessment has been aided by the publication of the medical emergencies in eating disorders (MEED) guidelines. Crucially, there is a need for further research into ARFID in order to develop evidence-based standardised guidelines for assessment, management and transition to adult services if required.
Crystal cells in echinoderms have been described in the literature as a type of coelomocyte (immune cell) containing a crystalline structure. Their putative function has been widely ascribed to osmoregulation but this assertion was never robustly tested. In the present paper, a review of crystal cells and crystalline structures provides evidence supporting a different identity and function. First, the same microcrystals can be found either free or encapsulated by a cell membrane (with or without a structure resembling a nucleus). Specifically, they are typically non-encapsulated when found inside tissues of internal organs and encapsulated when free floating in the hydrovascular or perivisceral fluids. Although usually individually packaged, microcrystals were also observed encapsulated in groups of up to four, with or without other particles. Their morphological features, coupled with their chemical and optical properties, match that of microcrystals of uric acid, described in other phyla, including chordates. Two pathways of excretion of these crystallised by-products were evidenced: rejected with sea water out of the respiratory tree and expelled via transrectal coelomoducts among coelomocyte aggregates. Overall, the present synthesis strongly supports that ‘crystal cells’ historically described as a distinct type of coelomocyte in holothuroids are phagocytes that have engulfed uric acid microcrystals generated as waste by metabolic activities.
Cognitive fatigability (CF), which refers to a decline in performance during sustained cognitive effort, can significantly impact people with multiple sclerosis (PwMS). This study examined the unmet needs related to perceived CF in PwMS.
Methods:
One hundred PwMS completed a survey assessing factors known to contribute to CF. Participants indicated whether each factor, including CF itself, was disruptive and whether adequate support was available to address these concerns. A factor identified as disruptive and insufficiently addressed was considered an unmet need (Need Index [NI] ≥50%).
Results:
Group-level analysis revealed no significant unmet needs, although fatigue (NI = 30.23), CF (NI = 22.96) and physical activity (NI = 19.55) were more frequently reported. Individual-level analyses revealed that unmet needs varied by community setting (rural vs urban) and socioeconomic status (SES) (lower vs higher SES), with rural participants and those with lower SES reporting higher rates of unmet needs. In addition, PwMS who indicated CF was an unmet need reported more difficulties across most contributory factors, including sleep quality, fatigue, cognitive impairment, depression and contextual factors. The presence of fatigue and CF combined contributed to greater unmet needs across various domains, especially fatigue, CF and cognitive impairment, compared to fatigue alone.
Conclusions:
Participants from rural and low socioeconomic backgrounds were more likely to have unmet needs. Notably, 36% of participants (N = 33) reported unmet needs related to perceived CF. The findings highlight the importance of tailoring future interventions to address identified needs more adequately.