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The radical right succeeds when minorities challenge the societal standing of majorities. In Central and Eastern Europe (CEE), research often focuses on the political gains of ethnic minorities. We build on this work by differentiating among (1) types of representation; (2) minority mobilization versus ally advocacy; and (3) politically mobilized versus socially marginalized ethnic minorities. First, we introduce a novel measure of representation based on the power, influence, and prestige afforded to ethnic minorities at the executive (cabinet) level. Second, we evaluate whether legislative descriptive representation, ethnic minority party coalition participation, and ethnic minority cabinet-level prestige are associated with radical-right aggregate electoral success and individual-level radical-right vote choice. Cabinet-level prestige consistently predicts radical-right success; descriptive representation and coalition participation have less robust associations. Third, experiments in Romania and Slovakia highlight the mechanism, underscoring that representation – namely the substantive representation of politically mobilized minorities – causes resentment among ethnic majorities. In sum, majority-minority relations continue to structure CEE electoral politics, and the politicization of minority gains remains a viable strategy for mobilizing radical-right support.
Narratives and frames have shaped the overdose crisis since its early stages. Efforts to control knowledge about the role of opioids in chronic pain have influenced clinical guidelines and prescribing behaviour. Dominant narratives shape policy by influencing how problems are defined, and which solutions are considered appropriate. A more nuanced understanding of how framing shapes interactions among stakeholders, including patients, clinicians, advocacy groups, industry, educators, and regulators, can clarify these dynamics. Engaging multiple perspectives, rather than relying on a single dominant narrative, offers a more effective path for addressing complex public health emergencies such as the overdose crisis.
Critical interpretive synthesis was introduced in 2006 to address various shortcomings of systematic reviews such as their limitations in synthesizing heterogeneous data, integrating diverse study types, and generating theoretical insights. This review sought to outline the methodological process of conducting critical interpretive syntheses by identifying the methods currently in use, mapping the processes that have been used to date, and highlighting directions for further research. To achieve this, a scoping review of critical interpretive syntheses published between 2006 and 2023 was conducted. Initial searches identified 1628 publications and after removal of duplicates and exclusions, 212 reviews were included in the study. Most reviews focused on health-related subjects. Authors chose to utilize the method due to its iterative, inductive, and recursive nature. Both question-based and topic-based reviews were conducted. Literature searches relied on electronic databases and reference chaining. Mapping to the original six-phase model showed most variability in use of sampling and quality assessment phases, which were each done in 50.7% of reviews. Data extraction utilized a data extraction table. Synthesis involved constant comparison, critique, and consolidation of themes into constructs, and a synthesizing argument. Refining critical interpretive synthesis methodology and its best practices are important for optimizing the utility and impact and ensuring findings are relevant and actionable for informing policy, practice, and future research.
In 1967, Klarner proposed a problem concerning the existence of reflecting n-queens configurations. The problem considers the feasibility of placing n mutually nonattacking queens on the reflecting chessboard, an $n\times n$ chessboard with a $1\times n$ “reflecting strip” of squares added along one side of the board. A queen placed on the reflecting chessboard can attack the squares in the same row, column, and diagonal, with the additional feature that its diagonal path can be reflected via the reflecting strip. Klarner noted the equivalence of this problem to a number theory problem proposed by Slater, which asks: for which n is it possible to pair up the integers 1 through n with the integers $n+1$ through $2n$ such that no two of the sums or differences of the n pairs of integers are the same. We prove the existence of reflecting n-queens configurations for all sufficiently large n, thereby resolving both Slater’s and Klarner’s questions for all but a finite number of integers.
This article explores the concept of transfer as it emerges in German-speaking academic discourse and considers its broader implications for the Global Public Literary Humanities. While transfer has become an established term in university policy, especially in Germany, its potential for literary studies remains under-examined. Building on both German and Francophone models, this article offers a nuanced framework that distinguishes between transfer and its synonyms—such as application, practice, communication, cooperation, and mediation—and proposes the concept of transferability as a means to sharpen theoretical and practical awareness regarding the conditions for successful transfer. This article presents a model that identifies both enabling conditions (such as relevance and resonance) and practical forms of transfer, arguing that transferability is shaped by ethical, esthetic, and anthropological considerations. Drawing on examples from current German debates (e.g., #RelevanteLiteraturwissenschaft, collaborative literary festivals, and citizen science projects), the analysis demonstrates that successful literary transfer is always co-creative and dialogical. Ultimately, this article calls for more institutional and structural efforts to enable transferability within literary studies and suggests that increased awareness of its prerequisites and possibilities for implementation can make academic work more responsive, inclusive, and socially engaged. This essay also advocates for extending the debate by incorporating concepts and practices from other linguistic and cultural traditions, thereby advancing the vision of Global Public Literary Humanities as a truly interconnected, dynamic, and transformative field. In doing so, this article hopes to encourage further critical reflection, experimentation, and the opening of new perspectives in research, teaching, and public engagement.
We consider the Schrödinger equation on the one dimensional torus with a general odd-power nonlinearity $p \geq 5$, which is known to be globally well-posed in the Sobolev space $H^\sigma(\mathbb{T})$, for every $\sigma \geq 1$, thanks to the conservation and finiteness of the energy. For regularities σ < 1, where this energy is infinite, we explore a globalization argument adapted to random initial data distributed according to the Gaussian measures µs, with covariance operator $(1-\Delta)^s$, for s in a range $(s_p,\frac{3}{2}]$. We combine a deterministic local Cauchy theory with the quasi-invariance of Gaussian measures µs, with additional Lq-bounds on the Radon-Nikodym derivatives, to prove that the Gaussian initial data generate almost surely global solutions. These Lq-bounds are obtained with respect to Gaussian measures accompanied by a cutoff on a renormalization of the energy; the main tools to prove them are the Boué-Dupuis variational formula and a Poincaré-Dulac normal form reduction. This approach is similar in spirit to Bourgain’s invariant argument [7] and to arecent work by Forlano-Tolomeo in [18].
Over the past two decades, the Canadian Arctic Archipelago has undergone significant glacier mass loss, driven primarily by surface melt. This study presents a detailed analysis of supraglacial drainage evolution along Ellesmere Island’s ∼830 km latitudinal extent using satellite imagery, historical aerial photographs and DEMs from 1959 to 2020. Analysis of five glaciers shows that drainage density (Dd) has increased over time, driven by the expansion of perennial rivers, especially at higher elevations. Far northern glaciers exhibit stable, well-developed drainage systems, while southern glaciers show a relatively greater increase in canyon development since 1959. Cold surface ice in the north supports higher Dd, while southern glaciers with extensive sinks (moulins and large crevasses) exhibit stronger surface-to-bed connectivity. Despite increased channelization, sinuosity changes remain statistically insignificant, reflecting dynamic canyon behavior governed by surface slope and meltwater discharge. Results align with modeled increases in melt, especially on southern glaciers where supraglacial systems have expanded most rapidly. Continued equilibrium line altitude rise under future warming is expected to intensify melt and result in the expansion of supraglacial drainage systems up-glacier, particularly for glaciers with large amounts of ice at mid-elevation.
This article examines women’s work in rural areas of the Republic of Venice between the seventeenth and eighteenth centuries, with a focus on the district of Padua. By applying the verb-oriented method to judicial sources, it reconstructs a detailed and nuanced picture of female labour, highlighting the extent and continuity of women’s economic activities. The findings show that women were engaged across all sectors of the economy, including sectors far beyond care and housework. They played an active role in agriculture, trade, and manufacturing. Moreover, their work was fully integrated into the household economy, structured around seasonal labour demands, and performed throughout the year. A comparison with previous studies suggests that women’s work in the Venetian countryside aligned closely with broader European patterns. These findings underscore the fundamental contribution of female labour to household survival, challenging long-standing assumptions about women’s economic roles in Italy and the Mediterranean.
We prove that every irreducible component of the coarse Kollár-Shepherd-Barron and Alexeev (KSBA) moduli space of stable log Calabi–Yau surfaces admits a finite cover by a projective toric variety. This verifies a conjecture of Hacking–Keel–Yu. The proof combines tools from log smooth deformation theory, the minimal model program, punctured log Gromov–Witten theory, and mirror symmetry.
Clozapine remains underused despite its unparalleled efficacy in treatment-refractory schizophrenia. One of the reasons for its underuse is the fear of severe neutropenia and its consequences.
Aims
To scrutinise the association between severe neutropenia and clozapine in a cohort of patients clinically diagnosed with clozapine-induced severe neutropenia.
Method
We used data from the South London and Maudsley National Health Service Foundation Trust’s anonymised case register, known as the Clinical Record Interactive Search. We extracted details of cases where clozapine use was associated with two consecutive neutrophil counts below 1.5 × 109/L. A panel of clinicians independently assessed each case. Agreement was reached on which cases clozapine was the likely or definite cause of the severe neutropenia, the risk to life and whether or not rechallenge with clozapine could be attempted.
Results
There were 96 cases where two consecutive neutrophil counts below 1.5 × 109/L were registered. The panel judged that 9 (9.4%) were definitely caused by clozapine and a further 11 (11.5%) were probably caused by clozapine. Overall, 18 (18.8%) patients should be precluded from ever receiving clozapine again according to the panel (all from the 20 cases where clozapine was the definite or probable cause). Of the remaining 76 cases of severe neutropenia the cause could not be determined in 60 cases, but in 11 cases the cause was benign ethnic neutropenia, in 2 others the cause was cancer chemotherapy, in 2 it was infections and in 1 it was laboratory error. In almost 80% of cases, clozapine was not the clear cause of the neutropenia observed.
Conclusions
The large majority of severe neutropenia episodes mandating cessation of clozapine may not be caused by clozapine. Threshold-based monitoring systems cause unnecessary stopping of clozapine because they lack the necessary specificity for clozapine-related blood disorders.
This guide provides a philosophical framework and practical advice for gathering, analyzing, and reporting a particular type of qualitative data. These data are obtained from including an open-text box following the key quantitative question in survey-style studies with the request to ‘Please explain your response’. While many studies currently collect such data, they often either fail to report or analyze it, or they conduct unstructured analyses with limited detail, often mistakenly referring to it as ‘thematic analysis’. Content analysis provides a well-established framework for analyzing such data, and the simplicity of the data form allows for a highly pragmatic and flexible approach. The guide integrates the concept of reflexivity from qualitative research to navigate the large number of researcher degrees of freedom involved in the process, particularly in working with the second coder. It begins by arguing for the value of this data, before outlining the guide’s philosophy, offering advice on maximizing the validity of your data, and addressing the common concern of confabulation. It then provides advice on developing a coding scheme, recruiting and collaborating with a second coder, and writing your report, considering the potential role of large language models at these various stages. Additionally, it provides a checklist for reviewers to evaluate the quality of a given analysis. Throughout the guide, a running example is used to demonstrate the implementation of the provided advice, accompanied by extensive example materials in the online repository, which can be used to practice the method.
A deep-learning-based closure model to address energy loss in low-dimensional surrogate models based on proper-orthogonal-decomposition (POD) modes is introduced. Using a transformer-encoder block with an easy-attention mechanism, the model predicts the spatial probability density function of fluctuations not captured by the truncated POD modes. The methodology is demonstrated on the wake of the Windsor body at yaw angles of $\delta = [2.5^\circ ,5^\circ ,7.5^\circ ,10^\circ ,12.5^\circ ]$, with $\delta = 7.5^\circ$ as a test case, and in a realistic urban environment at wind directions of $\delta = [-45^\circ ,-22.5^\circ ,0^\circ ,22.5^\circ ,45^\circ ]$, with $\delta = 0^\circ$ as a test case. Key coherent modes are identified by clustering them based on dominant frequency dynamics using Hotelling’s $T^2$ on the spectral properties of temporal coefficients. These coherent modes account for nearly $60 \,\%$ and $75 \,\%$ of the total energy for the Windsor body and the urban environment, respectively. For each case, a common POD basis is created by concatenating coherent modes from training angles and orthonormalising the set without losing information. Transformers with different size on the attention layer, (64, 128 and 256), are trained to model the missing fluctuations in the Windsor body case. Larger attention sizes always improve predictions for the training set, but the transformer with an attention layer of size 256 slightly overshoots the fluctuation predictions in the Windsor body test set because they have lower intensity than in the training cases. A single transformer with an attention size of 256 is trained for the urban flow. In both cases, adding the predicted fluctuations close the energy gap between the reconstruction and the original flow field, improving predictions for energy, root-mean-square velocity fluctuations and instantaneous flow fields. For instance, in the Windsor body case, the deepest architecture reduces the mean energy error from $37 \,\%$ to $12 \,\%$ and decreases the Kullback–Leibler divergence of velocity distributions from ${\mathcal{D}}_{\mathcal{KL}}=0.2$ to below ${\mathcal{D}}_{\mathcal{KL}}=0.026$.
In the last few years, Hindu nationalism’s effort to shape the Hindu identity of the nation has intensified. Apart from its move to assert cultural homogenisation over the diverse landscape, this ideology produces a newer understanding of spaces in the land. When it is read as a part of the broader Hindutva movement, the use of violence, bureaucratic overreach, or judicial intervention to rewrite the sacred topography of the land unmasks the territorial goal of Hindu Rashtra. The territorial manifestation of this ideology takes a strident effort inside the country to encroach and reclaim the spaces inhabited by the “other” as Hindu spaces in the name of the nation. This immediately establishes a clear and precise correlation between the spaces and the nature of the spaces. This territorialisation of the spaces indicates the spatial rearrangement of the public spaces to marginalise minorities, invisibilise Muslims, and push them into the “private” space.
Mathematical billiards is much like the real game: a point mass, representing the ball, rolls in a straight line on a (perfectly friction-less) table, striking the sides according to the law of reflection. A billiard trajectory is then completely characterized by the number of elastic collisions. The rules of mathematical billiards may be simple, but the possible behaviours of billiard trajectories are endless. In fact, several fundamental theory questions in mathematics can be recast as billiards problems. A billiard trajectory is called a periodic orbit if the number of distinct collisions in the trajectory is finite. We show that periodic orbits on such billiard tables cannot have an odd number of distinct collisions. We classify all possible equivalence classes of periodic orbits on square and rectangular tables. We also present a connection between the number of different equivalence classes and Euler’s totient function, which for any positive integer N, counts how many positive integers smaller than N share no common divisor with N other than $1$. We explore how to construct periodic orbits with a prescribed (even) number of distinct collisions and investigate properties of inadmissible (singular) trajectories, which are trajectories that eventually terminate at a vertex (a table corner).
There is an increasing global focus on gender diversity and equality in the workplace, particularly regarding women in leadership roles. Our study explores this focus in the wine industry in Australia, examining women's representation in CEO, winemaker, viticulturist, and marketing roles. By using results from a previous Australian study, we find that women have significantly increased their presence in all roles but one (marketing role) when comparing 2007–2013 with 2021–2023. Our study also confirms that women are more likely to be in winemaking and viticulturist roles, conditional upon a woman being in the CEO role. However, women in winemaking and viticulturist roles still lag behind women in leadership roles across other industries in Australia. We offer conclusions and directions for future research.
Heightened reactivity in the amygdala measured by functional magnetic resonance imaging during emotional processing is considered a potential biomarker for clinical depression. Still, it is unknown whether this is also true for depressive symptoms in the general population, and – when in remission after recurrent depressive episodes – it is associated with future episodes.
Methods
Using the UK Biobank population study (n = 11,334), we investigated the association of amygdala reactivity during negative facial stimuli, focusing on lifetime depression (trait), depressive symptoms (state), and the modulating effect of antidepressant (AD) treatment thereof. We employed normative modeling (NM) to better incorporate population heterogeneity of the amygdala activity.
Results
In line with a previous study, depressive symptoms (state) over the last 2 weeks were not associated with the amygdala reactivity signal. Rather, our results indicate a significant positive association (p = 0.03, ω2 = 0.001) between amygdala response and the recurrence of depressive episodes (trait). Longitudinal analysis revealed that the group that had experienced a single depressive episode before showed a significantly increased amygdala response after additional episodes (p = 0.03, ω2 = 0.017). ADs were not associated with amygdala response directly, but decreased associations within episode recurrence severity.
Conclusions
The amygdala response to negative stimuli was associated with an individual’s risk of recurrence of depressive episodes, and AD treatment reduced these associations. This study highlights the relevance of amygdala reactivity as a trait, but not a state biomarker for (recurrent) depression. Moreover, it demonstrates the benefit of applying NM in the context of population data.
Should voting rights be tied to citizenship? Over 20 million noncitizens pay taxes, own businesses and homes, send their children to schools, and make countless economic, social, and cultural contributions every day. Yet they cannot vote to select politicians who make policy that affects their daily lives. Today, noncitizens currently vote legally in local elections in 22 cities and towns in Maryland, Vermont, California, and Washington, DC. These practices have their roots in another little-known fact: noncitizens voted in 40 states at some point in time from the Founding until 1926. Noncitizens voted not only in local elections but also in state and federal elections, and they could hold office such as alderman. “Alien suffrage” was seen as a means to facilitate immigrant incorporation and citizenship, which it did in practice. This article examines the politics and practices of immigrant voting in the US, chronicling the rise and fall—and reemergence—of immigrant voting rights. It explores arguments for and against noncitizen voting, reviews evidence about its impact on policy and American political development, and considers its implications for immigration policy and democratic practice. Debate about immigrant voting rights can be viewed as a microcosm of broader debate about immigration, citizenship, and democracy reflected in scholarship and political conflict embroiling the nation, which holds valuable lessons for scholars and policy makers today. I argue, in a country where “no taxation without representation” was a rallying cry for revolution, such a proposition might not be so outlandish upon further scrutiny.
I study the optimal design of monetary incentives in experiments where incentives are a treatment variable. I propose a novel framework called the Budget Minimization problem in which a researcher chooses the level of incentives that allows her to detect a predicted treatment effect while minimizing her expected budget. The Budget Minimization problem builds upon the power analysis and structural modeling. It extends the standard optimal design approach by explicitly incorporating the budget as a part of the objective function. I prove theoretically that the problem has an interior solution under fairly mild conditions. To showcase the practical applications of the Budget Minimization problem, I provide examples of its implementation in several well-known experiments. I also offer a practical guide to assist researchers in utilizing the proposed framework. The Budget Minimization problem contributes to the experimental economists’ toolkit for an optimal design, however, it also challenges some conventional design recommendations.