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We study experimentally the starting vortices shed by airfoils accelerating uniformly from rest in superfluid helium-4 (He II). The vortices behave apparently as if they were moving in a classical Newtonian fluid, such as air or water. Specifically, the starting vortex positions obtained from the experimental data are found to be very close to those computed numerically in a Newtonian fluid, at sufficiently small times, when self-similar behaviour is expected to occur, and for Reynolds numbers ranging between approximately $5 \times 10^2$ and $5 \times 10^5$. The result indicates neatly that turbulent flows of He II can be very similar to classical flows of Newtonian fluids, when thermal effects can be neglected and at sufficiently large flow scales, i.e. the study demonstrates that He II could also be employed to study classical Newtonian flows.
This study examines how racial identity affects legislative responsiveness in Mexico using an email-based audit experiment. Emails from simulated Indigenous, Mestiza, and European-White constituents were sent to all 626 federal legislators to test whether perceived identity shapes replies and their quality. Contrary to expectations, Indigenous-named constituents received significantly higher response rates that were more personalized and helpful than their European-White counterparts, while Mestiza-named constituents showed no significant differences in response rates. We found no coalition-based differences, though power was limited, and responsiveness declined in districts with larger Indigenous populations, revealing how national inclusion norms may be moderated by local demographic and political dynamics.
Mountainous regions host globally unique biodiversity, but face growing threats from climate and land-use change. The Alps stand out as a key mountain range in Europe, where the ski industry is extensive and impacts ecosystems and their associated biodiversity. However, climate change is projected to reduce natural snow precipitation, thus understanding snow dynamics and the ski industry’s role is crucial for developing effective conservation strategies. Ski-piste creation generally has detrimental consequences for mountain biodiversity, yet pistes often retain substantial snow throughout spring that, when melting, may create favourable foraging conditions for mountain birds. This study investigates whether ski-pistes provide suitable foraging habitat and explores their broader importance for mountain avifauna. Field surveys in spring 2023 in the western Italian Alps recorded 17 bird species using the melting snow on ski-pistes as a foraging habitat. Snow presence was a significant factor influencing bird presence. Birds systematically selected areas with intermediate snow cover interspersed with muddy patches, a microhabitat that likely has a high availability of invertebrate prey emerging from the soil. Given that snow is retained on ski-pistes for longer than on the surrounding habitat, the pistes may represent a useful source of food for mountain birds in spring. However, this needs to be considered in relation to the negative impacts of skiing on alpine biodiversity, which may include a likely increased reliance on artificial snow in response to the projected decline in natural snow precipitation under climate change. Understanding these effects is essential to ensure that future conservation strategies support mountain bird communities without exacerbating the environmental costs associated with artificial snow production.
This article1sets out to reassess the idea, repeated by many scholars, that there was a bishop from the Central Asian city of Qumul (or Hami) who was present in Baghdad around the time when one patriarch of the Church of the East – Makkika II – was buried and another – Denḥa I – was consecrated. After an initial consideration of what we know about the city of Qumul/Hami, we examine the various authors who have held to this idea and the sources, both primary and secondary, which they invoke as proof that the idea is correct. Gradually moving back to the earliest witnesses, we eventually arrive at the Maronite scholar Joseph Assemani’s Bibliotheca Orientalis Clementino-Vaticana and the fourteenth-century primary source, Ṣalībā ibn Yūḥannā. A suggestion is made for how the idea originated and developed, thanks in part to the account of Marco Polo, but more definitively to Michel Le Quien’s Oriens Christianus.
Lexical borrowing may provide valuable clues about the sociohistorical context of language contact. Here we explore patterns of vocabulary transfer between languages from three families (Kx’a, Tuu, Khoe-Kwadi) comprising the linguistic unit commonly referred to as Southern African Khoisan. In our data set, 20% of 1,706 roots are shared between at least two families. By applying a carefully chosen set of linguistic and extralinguistic criteria, we were able to trace the origin of 71% of shared roots, with the remaining 29% constituting good candidates for ancient contact or shared common ancestry of the forager families Kx’a and Tuu. More than half of the shared roots for which an origin could be determined trace back to Khoe-Kwadi and were borrowed into languages of other families within two major confluence zones with different sociohistorical profiles: (i) the Central Kalahari characterized by egalitarian interaction between languages of all three families and (ii) the southern and south-western Kalahari Basin fringes showing unilateral transfer from Khoe-Kwadi-speaking herders into resident forager groups. The findings of this study complement genetic and archaeological research on southern Africa and testify to the value of linguistics in the multidisciplinary inference of contact and migration scenarios.
This collection gathers thirteen contributions by a number of historians, friends, colleagues and/or students of Jinty’s, who were asked to pick their favourite article by her and say a few words about it for an event held in her memory on 15 January 2025 at King’s College London. We offer this collection in print now for a wider audience not so much because it has any claim to be exhaustive or authoritative, but because taken all together these pieces seemed to add up to a useful retrospective on Jinty’s work, its wider context, and its impact on the field over the decades. We hope that, for those who know her work well already, this may be an opportunity to remember some of her classic (and a few less classic) articles, while at the same time serving as an accessible introduction to her research for anyone who knew her without necessarily knowing about her field, as well as for a new and younger generation of readers.
While apophatic theology has been quickly dismissed by the vast majority of analytic philosophers, Samuel Lebens is among the few who has tried to show that such a theological position is tenable by appealing to two main philosophical moves. The first move is that many of our claims about God are false (or nonsensical). The second move is that such false (or nonsensical) claims about God are illuminating and/or therapeutic. This article presents Lebens’s account of apophatic theology, and defends it from the main criticisms. However, it also shows that, contrary to what has been suggested by Lebens himself, the disjunction which appears in the first move has to be understood as exclusive, that is, either many of our claims about God are false or many of our claims about God are nonsense. Tertium non datur. Moreover, this article argues that, in both cases, Lebens’s account of apophatic theology stumbles upon some important issues. For, if many of our claims about God are taken to be false or nonsensical, Lebens fails to explain how such claims can be illuminating and/or therapeutic.
Motivational interviewing is a patient-centred communication approach designed to facilitate behavioural change by enhancing intrinsic motivation. Despite its widespread global utility, research on the training and applications of motivational interviewing among resident physicians in Oman remains untapped.
Aims
To examine the awareness, training experiences and clinical implementation of motivational interviewing among psychiatry and family medicine residents enrolled with the Oman Medical Specialty Board (OMSB).
Method
A qualitative study was conducted using semi-structured interviews and focus group discussions with 22 resident physicians from psychiatry and family medicine programmes. Data were analysed using thematic analysis to identify key themes regarding motivational interviewing training and its application in clinical settings.
Results
Three primary themes emerged: (a) residents’ understanding and application of motivational interviewing principles, (b) barriers to the integration of motivational interviewing into clinical practice, such as time constraints and insufficient training, and (c) the need for culturally adapted approaches to motivational interviewing tailored to Omani patients. Although participants appreciated the utility of motivational interviewing to improve patient engagement, they reported inconsistent training and limited opportunities to practise the technique in clinical settings.
Conclusions
The study highlights significant gaps in motivational interviewing training and practice within Oman’s residency programmes. It underscores the necessity for comprehensive, structured motivational interviewing curricula that are sensitive to the local context. Enhancing practical training opportunities may improve the integration of motivational interviewing into patient care, particularly in managing chronic diseases and addiction.
We investigate the consequences of periodic, on–off glucose infusion on the glucose–insulin regulatory system based on a system-level mathematical model with two explicit time delays. Studying the effects of such infusion protocols is mathematically challenging yet a promising direction for probing the system response to infusion. We pay special attention to the interplay of periodic infusion with intermediate-time-scale, ultradian oscillations that arise as a result of the physiological response of glucose uptake and back-release into the bloodstream. By using numerical solvers and numerical continuation software, we investigate the response of the model to different infusion patterns, explore how these patterns affect the overall levels of glucose and insulin, and how this can lead to entrainment. By doing so, we provide a road-map of system responses that can potentially help identify new, less-invasive, test strategies for detecting abnormal responses to glucose uptake without falling into lockstep with the infusion pattern.
In the early months of 2020, governments faced the rapid spread of COVID-19. To navigate the storm of conflicting information about the danger posed by this new disease, countries sought guidance about when and how to respond to it. We argue that the World Health Organization (WHO) played a central role in the diffusion of policies against COVID-19 by exercising leadership. We develop the concept of leadership as a diffusion mechanism to explain how the WHO influenced governments to close schools and workplaces and cancel public events within weeks, despite its lack of strong enforcement mechanisms. Results from five event-history models show the significance of the WHO’s pandemic declaration on March 11, 2020 that mobilized countries to adopt the measures recommended by the organization. However, that declaration did not affect the diffusion of policies that the WHO advised against adopting.
Comprehensive cognitive remediation improves cognitive and functional outcomes in people with serious mental illness, but the specific components required for effective programs are uncertain. The most common methods to improve cognition are facilitated computerized cognitive training with coaching and teaching cognitive self-management strategies. We compared these methods by dismantling the Thinking Skills for Work program, a comprehensive, validated cognitive remediation program that incorporates both strategies.
Methods
In a randomized controlled trial we assigned 203 unemployed people with serious mental illness in supported employment programs at two mental health agencies to receive either the full Thinking Skills for Work (TSW) program, which included computerized cognitive training (based on Cogpack software), or the program with cognitive self-management (CSM) but no computer training. Outcomes included employment, cognition, and mental health over 2 years. To benchmark outcomes, we also examined competitive work outcomes in a similar prior trial comparing the TSW program with supported employment only.
Results
The TSW and CSM groups improved significantly on all outcomes, but there were no differences between the groups. Competitive work outcomes for both groups resembled those of the TSW program in a prior trial and were better than the supported employment-only group in that study, suggesting that participants in both groups benefited from cognitive remediation.
Conclusions
Providing facilitated computerized cognitive training improved neither employment nor cognitive outcomes beyond teaching cognitive self-management strategies in people receiving supported employment. Computerized cognitive training may not be necessary for cognitive remediation programs to improve cognitive and functional outcomes.
Complex, knowledge-intensive projects present challenges in terms of defining the work and determining roles. Time pressure makes these challenges more acute. External leadership can provide necessary direction and shape, giving the work a clear focus guiding the team’s efforts. With hackathons and rapid product prototyping more feasible than they ever have been, collaborations that fast-track innovation by drawing together teams of unfamiliar experts are more common than ever.
Method
Drawing on the process perspective on creative action, we seek to understand the generation of new ideas and solutions when teams are working within an extremely brief time frame of one week. The influence of mentors on these interactions has received limited attention. We fill this gap through a study of fifteen case teams who participated in a week-long boot camp where they generated proposals for public health studies, guided by mentors who were experts in the field. The teams’ proposals were evaluated by independent panels, and the evaluations provided metrics for team success.
Results
Our results suggest that even in short-term teams, the timing of mentor interventions is critical to team success.
In mammals, pregnancy and lactation are marked by maternal calcium stress and bone resorption, leading to reduced bone mineral density. In humans, these periods may partly explain the higher prevalence of osteoporosis in older women compared with men, but lactation patterns in modern humans may reflect cultural influences rather than natural conditions. The extent to which these findings apply to wild-living mammals remains unknown. We measured urinary C-terminal crosslinking telopeptide of Type I collagen (CTX-I) levels, a bone resorption marker, during pregnancy in wild and zoo-housed bonobos (Pan paniscus) and during lactation in wild bonobos. Studying wild-living primates such as bonobos can provide insights into ancestral reproductive adaptations. We found an increase in CTX-I levels towards the end of pregnancy in zoo-housed and primiparous wild females. Contrary to expectations, CTX-I levels during early lactation are lower than in other reproductive phases. This pattern diverges from the assumption that lactation increases bone resorption. Our findings suggest that wild bonobos may rely on a combination of physiological and behavioral strategies to modulate bone metabolism during lactation. Bone resorption may serve as a physiological back-up when behavioral or dietary strategies cannot fully meet calcium demands. These flexible responses, shaped by fluctuating environmental conditions and prolonged maternal investment, provide insight into evolutionary pressures on skeletal health and may inform strategies to mitigate bone loss in humans.
In this article, we focus on the systemic expected shortfall and marginal expected shortfall in a multivariate continuous-time risk model with a general càdlàg process. Additionally, we conduct our study under a mild moment condition that is easily satisfied when the general càdlàg process is determined by some important investment return processes. In the presence of heavy tails, we derive asymptotic formulas for the systemic expected shortfall and marginal expected shortfall under the framework that includes wide dependence structures among losses, covering pairwise strong quasi-asymptotic independence and multivariate regular variation. Our results quantify how the general càdlàg process, heavy-tailed property of losses, and dependence structures influence the systemic expected shortfall and marginal expected shortfall. To discuss the interplay of dependence structures and heavy-tailedness, we apply an explicit order 3.0 weak scheme to estimate the expectations related to the general càdlàg process. This enables us to validate the moment condition from a numerical perspective and perform numerical studies. Our numerical studies reveal that the asymptotic dependence structure has a significant impact on the systemic expected shortfall and marginal expected shortfall, but heavy-tailedness has a more pronounced effect than the asymptotic dependence structure.
The “EU Vaccines Strategy” launched by the European Commission in June 2020 aimed to ensure vaccine safety, equitable access, affordability, swift distribution, and global solidarity for COVID-19 vaccines. This study critiques the Commission’s centralized procurement approach, focusing on Advance Purchase Agreements (APAs) through a literature review, policy analysis, and a case study of the EU-AstraZeneca’s APA. It identifies critical challenges, including transparency deficits, accountability gaps, and anticompetitive practices by vaccine producers that undermine equitable access. Drawing on these insights, the study proposes the FACER Framework — Fairness, Accountability, Competition Law, Ethics of Innovation, and Resilience — a novel model integrating the Treaty on the European Union (TEU) and the Treaty on the Functioning of the European Union (TFEU) oversight with ethical principles. By embedding legal and moral accountability, FACER offers EU policymakers a robust tool to enhance vaccine strategy and equity in future health crises.
Gastrointestinal (GI) nematode infections represent a significant health burden globally, affecting both humans and livestock. Traditional in vitro models to study host–parasite interactions, such as immortalized cell lines, have limitations that hinder the full understanding of these complex relationships. Organoid technology has emerged as a promising alternative, offering a physiologically relevant platform to study host–nematode interactions in vitro. Organoids are three-dimensional structures comprising differentiated cell types that recapitulate features of the corresponding organ. Technological advances for growing, maintaining and manipulating organoids have increased their applications to model infections, inflammation and cancer. This review discusses recent work using GI organoids to advance understanding of nematode–host interactions and modulation of GI epithelial cells. Additionally, we review studies that co-cultured GI organoids with innate lymphoid cells to study epithelial-immune cell cross-talk in the context of nematode infection. By bridging the gap between reductionist cell culture systems and whole-organism studies, organoids offer a powerful platform for investigating complex host–nematode interactions, and for developing and screening novel therapeutics.
Research demonstrates that English- and French-speaking Canadians differ in a wide range of attitudes, including their political preferences, their vision of the Canadian federation and their national identity. In this article, we ask whether individual bilingualism is associated with a decrease in the attitudinal differences between anglophones and francophones. Using survey data collected in the summer of 2023, we attempt to determine whether knowledge of the French language is related to an increase in the responsiveness of English-speaking citizens toward issues that typically preoccupy French-speaking Canadians. Our analyses suggest that knowledge of French as a second language is strongly linked to the political preferences of Canadian citizens but does not bridge the attitudinal gap between Canada’s two main language groups. These results highlight the relevance of considering the different languages that people speak—and not just their mother tongue—to understand their political attitudes.
Providing psychotherapy at 50 sessions in a year (starting twice weekly) led to faster and greater improvements in depression and personality functioning compared to 25 sessions, starting weekly for patients with depression and personality disorder (PD). This study reports long-term dosage effects at 18 and 24 months.
Methods
In a pragmatic, double-randomized clinical trial, 246 outpatients with depression and PD were assigned to (1) 25 or 50 sessions and (2) Short-term Psychodynamic Supportive Psychotherapy (SPSP) or Schema Therapy (ST). Depression severity was assessed with the Beck Depression Inventory-II. Secondary outcomes included diagnostic remission of depression (MINI-plus), PD (SCID-II/SCID-5-P), and treatment-specific measures. Intention-to-treat analyses were conducted.
Results
At 18 and 24 months, BDI-II means did not differ between dosage groups (19.0 for 25 sessions versus 19.1 for 50 sessions; d = −0.01; 95% CI = −0.35-0.37, p = 0.96). The lower-dosage group improved during follow-up (−2.6 BDI points, p = 0.031), which may be partly attributed to additional therapy received by a subgroup. Remission rates at 24 months were 66% for depression and 76% for PD, with no differences between conditions.
Conclusions
Higher psychotherapy dosage led to faster initial improvements, but long-term outcomes were not superior to those achieved with a lower dosage. These results should be interpreted with caution, as unregulated treatment during follow-up reduced the power to detect significant dosage effects. Both SPSP and ST provide viable alternatives to treatments focused solely on depression.
As artificial intelligence grows, human–robot collaboration becomes more common for efficient task completion. Effective communication between humans and AI-assisted robots is crucial for maximizing collaboration potential. This study explores human–robot interactions, focusing on the differing mental models used by humans and collaborative robots. Humans communicate using knowledge, skills, and emotions, while robotic systems rely on algorithms and technology. This communication disparity can hinder productivity. Integrating emotional intelligence with cognitive intelligence is key for successful collaboration. To address this, a communication model tailored for human–robot teams is proposed, incorporating robots’ observation of human emotions to optimize workload allocation. The model’s efficacy is demonstrated through a case study in an SAP system. By enhancing understanding and proposing practical solutions, this study contributes to optimizing teamwork between humans and AI-assisted robots.