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The extent to which legislators pursue their privately held preferences in office has important implications for representative democracy and is exceedingly difficult to measure. Many models of legislative decision-making tacitly assume that members are willing and able to carry out the wishes of their constituents so as to maximize their reelection prospects and, in so doing, relegate their personal preferences. This project explores this assumption by examining the role that members’ place of birth plays in shaping legislative behavior, apart from other politically relevant factors like partisanship. We find that birthplace exerts an independent influence on members’ voting behavior. Using a variety of geographic measures, we find that members who are born in close proximity to one another tend to exhibit similar patterns in roll call voting, even when accounting for partisanship, constituency attributes, and a variety of other determinants of voting. We also demonstrate in a secondary analysis that the agricultural composition of members’ birthplace influences their support for agricultural protection. Our findings suggest that members’ personal history shapes the representational relationship they have with their constituents.
Cartographic representations of Kashmir and Taiwan act as sites upon which Indian and Chinese state power is exercised to govern the logics of visibility and legibility for these two regions. Despite the differences in regime type, these major non-Western powers represent Kashmir and Taiwan respectively as internal and integral parts of their sovereign territorial form. In this article, we consider two cases that have not hitherto been studied together in International Relations (IR), putting forward ‘cartographic imaginaries’ as a framework to reveal systematic analytical dynamics in relation to representation, nationalism, and diaspora. Cartographic imaginaries are sites of productive power that evoke certain emotions and carry a set of ideas relating to territory that can be naturalised through repeated exposure. We present in-depth investigations providing a range of examples to trace Indian and Chinese states’ efforts, both domestic and international, involved in constructing and controlling cartographic imaginaries of Kashmir and Taiwan. Our analysis relates to significant current concerns in IR about critiques of imperial cartography, impact of rising powers on global order dynamics, and transnational governance of diaspora. Our framework thus demonstrates the connexions between affect, visuality, and state power and offers empirical insights into non-Western projections of imperialism on a global scale.
Here we present a novel approach to evaluate peripheral blood mononuclear cell vascular adhesion using a microfluidic model designed to approximate the complexity of a human arteriole. While EC monolayer assays are commonly used to investigate leukocyte-EC interactions, we hypothesized that our single channel arteriole (SCA) on a chip would recapitulate the microvasculature more accurately and provide additional insight into the initial stages of atherogenesis.
Methods:
This model is comprised of stromal cells embedded in a hydrogel surrounding a channel lined by endothelial cells (EC) that has an inner diameter approximating a small arteriole. Under physiologic shear conditions, the EC take on a phenotype distinct from monolayer cultures, including alignment with the direction of flow.
Results:
Significant differences were found between the SCA and monolayer cultures in the expression of key EC and stromal cell markers, including ICAM-1, VCAM-1, PDGFB, aSMA, and KLF2. Indeed, flow-induced PDGFB expression likely mediated the recruitment and differentiation of αSMA-positive cells to the vessel wall. Importantly, the vessels were responsive to stimulation by inflammatory mediators, showing both increased leukocyte adhesion and increased permeability. Finally, mechanically mediated protrusion of the vessel wall into the lumen disrupted flow, producing increased shear over the vessel wall.
Conclusion:
In summary, our studies demonstrate the utility of the SCA model for studies of small vessel physiology under both normal and disrupted flow and to lay the groundwork for further development into a model for atherosclerosis. Additionally, our data emphasize the advantages of complex 3D assays over more traditional 2D cultures.
This article uses letters from BL, ms Lansdowne 99 to explore how a diverse group of individuals experiencing mental and emotional distress utilised religious ideas as a primary means of interpreting their experience and expressing themselves to those in authority in Elizabethan England. It shifts emphasis away from the causes and towards the construction and experience of distress. It argues that such letters shed important light on the character and progress of the English Reformation by the closing decades of the sixteenth century, as well as on the operation of the process of Reformation itself.
Dirofilaria repens is the primary etiological agent of human dirofilariosis in the Old World, with Italy reporting the highest number of cases in Europe. This study describes two new cases of D. repens infection in humans, in southern Italy, where canine dirofilariosis is endemic. The first case involved a 33-year-old man from Caserta (Campania, Southern Italy) who presented with a subcutaneous mass on the upper eyelid. Surgical excision revealed an immature female D. repens worm measuring 14 cm, lacking microfilariae in both the uterus and peripheral blood. The second case was a 67-year-old man from Pozzuoli (Metropolitan City of Naples, Southern Italy) with an oval-shaped nodule in the left frontal scalp region. A live gravid female D. repens worm measuring 15–16 cm was extracted, also without microfilariae in the peripheral blood and no male worm detected. PCR sequencing confirmed a 100% match with D. repens. Both patients tested positive for D. repens antibodies by IgG ELISA. These cases underscore the continuous spread of human dirofilariosis in southern Italy and highlight diagnostic challenges due to variable clinical presentations. The discovery of a gravid female without microfilaremia suggests complexities in the parasite’s life cycle in humans, challenging the notion of humans as strict dead-end hosts. Given the rising prevalence in both humans and dogs, a comprehensive epidemiological study is recommended. Inclusion of dirofilariosis in the national surveillance system for notifiable diseases would improve case identification and tracking, aiding in better monitoring and control of this zoonotic infection.
Using a recent result of Bowden, Hensel and Webb, we prove the existence of a homeomorphism with positive stable commutator length in the group of homeomorphisms of the Klein bottle which are isotopic to the identity.
Using a laboratory experiment, we investigate complexity in decision problems as a cause of failures in contingent reasoning. For this purpose, we introduce three dimensions of complexity to a decision problem: the number of contingencies, the dominance property of choices, and reducible states. Each decision problem is designed to reflect variations in complexity across the three dimensions. Experimental results show that the number of contingencies has the most significant effect on failures in contingent reasoning. The second dimension, the dominance property of choices, also has a statistically significant effect, though the effect size is smaller than in the existing literature. In contrast, the third complexity dimension has no impact; presenting the decision problem in a reduced or reducible form does not change subjects’ performance on contingent reasoning. Additionally, we examine the Power of Certainty and show its existence. This effect is particularly pronounced when the number of contingencies is large.
Considering the alarming energy demand for cooling and seeking sustainable cooling alternatives to over-reliance on air conditioning, our pre-registered study is the first attempt to apply social norm nudges on two cooling behaviors – lighter clothing and the use of personal cooling devices (PCDs). To examine and compare the effectiveness of a descriptive norm message, an injunctive norm signal from leadership, and the two norms combined, we conducted an online randomized controlled survey experiment among financial employees (n = 743) in Guangdong, China. We measured their behavioral intentions before and after the intervention, and their level of commitment to these behaviors as an alternative outcome. We found that while single-norm conditions did not lead to desirable increases in lighter clothing, the both-norm condition nudged participants toward selecting lighter work clothes and boosted commitment to lighter clothing. Outcomes related to the use of PCDs were not affected by any of the norm conditions. These mixed findings present a cautionary tale for designing social norm interventions in office spaces and highlight the boundaries of their effectiveness in energy-saving behaviors.
The concept of security, with its various dimensions, is fundamental to the field of ageing literature. However, feeling safe does not always equate to feeling at ease or being comfortable with people and places. Building on these premises, this article presents and analyses the factors involved in the perception of security and social safeness among women ageing in a top-down co-housing project and a nursing home in Italy. This country has one of Europe’s oldest populations, and the ageing population phenomenon is particularly notable in the Veneto region. In response to changing demographics, the search for alternative housing solutions and associated innovative paradigms of care and support has been gaining ground in recent years. Our study analysed data gathered from women who decided not to age in place. Fieldwork was carried out in one of the most densely populated provinces in the Veneto region during 2022 and 2023. The methodology was qualitative and consisted of in-depth interviews, a focus group and a workshop. Participants were 11 self-sufficient older women, aged 75 and over, living in these facilities. Among the elements that contribute to the perception of social safeness, the following stood out: material and structural factors, physical and emotional factors, relational factors and factors linked to independence and autonomy. Finally, the article stresses the need to study social safeness in greater depth, as it could become a new line of social science research capable of providing relevant information on the housing needs of older adults.
Debris flows are a growing natural hazard as a result of climate change and population density. To effectively assess this hazard, simulating field-scale debris flows at a reasonable computational cost is crucial. We enhance existing debris flow models by rigorously deriving a series of depth-averaged shallow models with varying complexities describing the behaviour of grain–fluid flows, considering granular mass dilatancy and pore fluid pressure feedback. The most complete model includes a mixture layer with an upper fluid layer, and solves for solid and fluid velocity in the mixture and for the upper fluid velocity. Simpler models are obtained by assuming velocity equality in the mixture or single-layer descriptions with a virtual thickness. Simulations in a uniform configuration mimicking submarine landslides and debris flows reveal that these models are extremely sensitive to the rheology, the permeability (grain diameter) and initial volume fraction, parameters that are hard to measure in the field. Notably, velocity equality assumptions in the mixture hold true only for low permeability (corresponding to grain diameter $d=10^{-3}$ m). The one-layer models’ results can strongly differ from those of the complete model, for example, the mass can stop much earlier. One-layer models, however, provide a rough estimate of two-layer models when permeability is low, initial volume fraction is far from critical and the upper fluid layer is very thin. Our work with uniform settings highlights the need of developing two-layer models accounting for dilatancy and for an upper layer made either of fluid or grains.
Homelessness abounds today in various forms of displacement and as a pervasive condition of unbelonging. It ruins health, lives, communities, habitats, creativity, and hope. This Element argues that for theology to play its part in ending homelessness, it must better understand its own concept of 'home'. The Element proposes a vision of home capable of resisting the tacit, mistaken theology of home that undergirds the various iterations of modern homelessness. Weaving biblical and ritual sources, the argument constructs theological responses to the twin forces of consumerism and nationalism which, alloyed with sexism and racism, constitute the time of homelessness in which we live. It asks the reader to imagine home as 'participating instead of possessing' in every sphere of life, in pursuit of a theology of home capable of preventing homelessness and not merely ministering to people experiencing it. This title is also available as Open Access on Cambridge Core.
Building on our previous work on enriched universal algebra, we define a notion of enriched language consisting of function and relation symbols whose arities are objects of the base of enrichment $\mathcal {V}$. In this context, we construct atomic formulas and define the regular fragment of our enriched logic by taking conjunctions and existential quantification of those. We then characterize $\mathcal {V}$-categories of models of regular theories as enriched injectivity classes in the $\mathcal {V}$-category of structures. These notions rely on the choice of an orthogonal factorization system $(\mathcal {E},\mathcal {M})$ on $\mathcal {V}$ which will be used, in particular, to interpret relation symbols and existential quantification.
Consumers play an important role in regulating labor rights in global supply chains, either by punishing companies that violate labor rights or rewarding those that market fair labor practices. There is, however, currently limited understanding of how consumer demand can be effectively harnessed to protect freedom of association and collective bargaining (FACB) rights in garment-exporting countries. Through a series of conjoint experiments, we test the strength of consumer demand for FACB rights relative to other labor and environmental standards, and manipulate price and information frames to analyze the extent to which a business case exists to promote FACB rights. We find that consumers display willingness to pay premiums for various ethical labels around labor protections, indicating a business case for promoting ethical labor standards in supply chains. However, we also find that consumer demand for certain labor rights—including FACB rights and payment of a living wage—can diminish considerably in the context of price increases, thus limiting the profits firms might accrue by marketing labor rights protections. Our results open up the black box of consumer demand for different labor standards and evaluate the different modes through which consumers can influence labor protections in the global economy.
Rugged terrain is a landscape characteristic that has complex and often contradictory impacts on the size, geographic distribution, and economic vitality of locations. The USDA ERS’s Area and Road Ruggedness Scales provide two different types of information on the relative topographic variation of 2010 census tracts. These data characterize both the overall landscape and land where people travel. However, researchers frequently conduct analyses at larger geographic scales, such as counties. In this paper, we describe how the Area and Road Ruggedness Scales data were created and suggest several methods of aggregating the data to the county level. We use correlations and regressions of natural amenities on net migration to compare the suitability of our suggested county-level area ruggedness measures to the topography measure from the Natural Amenities Scale. We find that, despite data loss due to aggregation, county-level area ruggedness measures can serve as reasonable proxies for topographical amenities. However, they do not capture certain landscape features that positively influence migration.
The pre-Critical Kant holds that God is the ground of the possibility of all predicates. Yet it is not clear how God does this. A common approach is to distinguish between fundamental predicates, which God grounds directly by instantiating them, and derivative predicates, which God grounds indirectly. This essay argues that we should not distinguish between two sorts of predicates, some grounded directly and some grounded indirectly. We should distinguish between two sorts of grounding relations. As I will show, this dualism about grounding is both justified by the text and gives a satisfactory solution to the ‘how’ question.
Social scientists have long been interested in elite cohesion in American society, recognizing its potential implications for democracy and governance. While empirical research has focused on corporate elites and, in particular, on cohesion derived from shared board memberships, cohesion among those in the highest positions in the American state and historical change in that cohesion have been little studied. Drawing on a novel dataset of the career histories of 2,221 people who were appointed to these elite positions between 1898 and 1998, I examine whether administrative elites, prior to their elite appointment, attended the same educational institutions or worked in the same agencies of the federal government at the same time. I find evidence of increasing elite cohesion during the twentieth century. Educational cohesion increases significantly in the three decades following the World War II and then declines slightly toward the end of the century. This increase goes hand in hand with a change from college to graduate education as the primary site generating educational cohesion. Federal government workplace cohesion increases markedly in the 1930s and 1940s and then remains high. As people are appointed to different organizations within the American state, their educational and workplace connections create inter-agency networks that, it is expected, facilitate mutual understanding and coordination and thus help integrate the American administrative state.
This chapter considers the costs of long-term care for service users and their families, and the policies that are necessary for adequate financial protection. The main focus is on home care services due to the substantial gap in evidence regarding their affordability. Given the widespread preference for home-based care, particularly in Europe where the majority of long-term care users reside at home, understanding the financial implications of these services is crucial. While decisions about home care primarily prioritize users’ wellbeing, financial considerations also shape care arrangements. Overall, common protective mechanisms such as caps on out-of-pocket payments income-based and means tests seem unable to successfully protect long-term care users from experiencing catastrophic spending.