Endometrial receptivity is the ability of the endometrium to accept embryos. Thus, endometrial receptivity dysfunction is an important factor leading to embryo implantation failure. A good endometrial receptivity provides a suitable environment for embryo implantation, improving the embryo implantation rate. The “implantation window” stage, or the receptive stage of the endometrium, is regulated by various hormones, genes, proteins and cytokines, among which microRNAs (miRNAs) and their target genes have a regulatory effect on endometrial receptivity. This review outlines the relationship between endometrial receptivity and pregnancy, the mRNAs and related signalling pathways that regulate endometrial receptivity, and the regulatory role of miRNA in endometrial receptivity, providing a deeper understanding of the regulatory mechanisms of miRNA on endometrial receptivity in humans and animals and reference for the endometrial receptivity-related research.

This paper presents an artificial neural network (ANN)-based nonlinear model predictive visual servoing method for mobile robots. The ANN model is developed for state predictions to mitigate the unknown dynamics and parameter uncertainty issues of the physics-based (PB) model. To enhance both the model generalization and accuracy for control, a two-stage ANN training process is proposed. In a pretraining stage, highly diversified data accommodating broad operating ranges is generated by a PB kinematics model and used to train an ANN model first. In the second stage, the test data collected from the actual system, which is limited in both the diversity and the volume, are employed to further finetune the ANN weights. Path-following experiments are conducted to compare the effects of various ANN models on nonlinear model predictive control and visual servoing performance. The results confirm that the pretraining stage is necessary for improving model generalization. Without pretraining (i.e., model trained only with the test data), the robot fails to follow the entire track. Weight finetuning with the captured data further improves the tracking accuracy by 0.07–0.15 cm on average.

Moritz Altenried's The Digital Factory (2022) accomplishes in just under two hundred pages what many other books twice that length have struggled with: assembling a concise yet readable introductory map to the global, fragmented, and too-often hidden landscape of digitally-mediated capitalism. But the digital factory itself is an incomplete concept, almost always requiring us to look for the external and contingent labor support hidden just outside of its supposedly totalizing network of logistics, robotics and algorithms.

This paper introduces a new set of comprehensive and cross-country-comparable indexes of migration policy selectivity. Crucially, these reflect the multidimensional nature of the differential treatment of migrants. We use these indexes to study the evolution of migration policy selectivity and estimate how they affect migration flows. Combining all publicly available and relevant data since WWII, we build three composite indexes that identify selectivity in terms of skills, economic resources and nationality. First, we use these to characterize migration policies in 42 countries between 1990 and 2014. Second, we examine the relationship between the selectivity of migration policy and migration flows. Each of the three dimensions of migration policy is found to correlate strongly and significantly with both the size and structure of migration flows.

Functional decline following hospitalization remains an important problem in health care, especially for frail older adults. Modifiable factors related to reduction in harms of hospitalization are not well described. One particularly pervasive factor is emergency department (ED) boarding time; time waiting from decision to admit, until transfer to an in-patient medical unit. We sought to investigate how the functional status of frail older adults correlated with the length of time spent boarded in the ED. We found that patients who waited for 24 hours or more exhibited functional decline in both the Barthel Index and Hierarchical Assessment of Balance and Mobility and an increase in the Clinical Frailty Scale from discharge to 6 months post discharge. In conclusion, there is a need for additional investigation into ED focused interventions to reduce ED boarding time for this population or to improve access to specialized geriatric services within the ED.

This essay reflects the journey of two business scholars, Stephen X. Zhang and Jiyao Chen, who ventured into mental health research during the COVID-19 pandemic. We experienced first-hand how health sciences have operated their publication systems in ways that uphold scientific standing while addressing real-world problems. In doing so, we found the publishing expectations and norms in health and medical sciences to be vastly different from those in management. This essay further discusses aspects such as the preference for evidence over theory, the relationship with basic sciences, diverse evaluation criteria, encouragement of exploration and replication, timeliness, and democratization and inclusivity of scholarship as concrete steps of responsible research.

The Chinese Loess Plateau (CLP), recognized as the world's largest loess plateau, has been a subject of ongoing debate regarding the continuity of its sedimentary loess sequence due to its intricate depositional environment. In this study, we conducted dating on a 9.8-m-long Malan loess core obtained from the Sanmen Gorge in the southern CLP using optically stimulated luminescence (OSL). The OSL dates indicate loess deposition between 52.4 and 11.3 ka, with no apparent hiatus on a millennial scale, and a sedimentation rate (SR) exhibiting six distinct episodes. Additionally, a comprehensive review of 613 OSL ages from 18 sections at 14 sites across the CLP was conducted. The results reveal loess deposition at most sites shows no apparent hiatus on a millennial scale over the past 60 ka, except for two specific locations. High SR episodes during Marine Isotope Stage (MIS) 3 across the CLP were attributed to heightened dust emissions from the source region and an enhanced dust deposition efficiency, while MIS 2 deposits were influenced by an intensified East Asian winter monsoon. Low SR episodes during MIS 1 at most sites were likely associated with reduced atmospheric transportation and pedogenesis. Spatially heterogeneous SR variations across the CLP might be influenced by local depositional environments.

Sanctuary cities define themselves as metropoles that refuse to share information, personnel, and facilities with federal immigration authorities to police immigrants. While research suggests that sanctuary cities contest the criminalization of migration, a growing literature depicts how these urban sanctuaries could, in practice, perpetuate hierarchies and exclusionary politics against noncitizens. Yet, most of these studies conceive of urban sanctuary as local policies designed to challenge federal power and, thus, fail to fully capture how sanctuary policies could actually rely on the criminalization of migration to govern cities’ political problems. Drawing upon 1,900 pages of archival materials and 100 newspaper articles, this article takes the case of Chicago to study how and why the urban sanctuary expands immigrants’ rights while reinforcing policing with punitive implications for Latino “undeserving” noncitizens. As a form of racialized governance, I argue that Chicago’s sanctuary policies activate a set of punitive exceptions that—in response to distinct political urgencies—allow law and immigration enforcement to converge and control Latino undocumented workers, “criminals,” and “gangs.” This study not only challenges the premise that sanctuary cities necessarily resist federal power but also illustrates how they could strengthen the legitimacy of the state and racialized police power.

This study investigated the mental health significance of Barack Obama’s 2012 presidential re-election among Blacks. Upon his re-election, we hypothesized Blacks would either feel symbolic empowerment or relative deprivation. They would feel symbolic empowerment because a man who identifies as Black won re-election to the nation’s highest office. His second victory should generate optimism, given his status as a historic first. Alternatively, they would feel relative deprivation because The Great Recession from 2007 to 2009 curtailed what Obama could achieve. More important, he withered when afforded opportunities to challenge White supremacy and championed individual responsibility. Using a quasi-experimental design with nationally representative survey data from the 2012 Behavioral Risk Factor Surveillance System (BRFSS), we predicted Blacks’ preelection and postelection poor mental health days. We found no time period main effects. However, Black men with less than a college degree experienced 1.11 more poor mental health days postelection whereas Black men with a college degree or more experienced 2.93 fewer poor mental health days postelection. These findings support relative deprivation theory.

The expeditions removing and excavating antiquities at the site of Xanthos in Lycia (1841–4) have been highlighted by scholars as setting a new precedent for whole-sale collection from a single site, and the support – through the national museum and the Royal Navy – of the British government for archaeological endeavours. Questions remain, however, regarding the failure of the first mission to remove the antiquities. According to the current narrative, the blame rests on the navy officer assigned to support Charles Fellows. Based on archival research, this article presents the concerns that Commander Thomas Graves had with the undertaking. His perspective sheds new light on how ill-planned the initial attempts were, and consequently how much was learned. The obstacles encountered in the first Xanthos expedition spurred developments in archaeological practice, introduced by people of non-academic professions.