This case study uses the concept of ecosystem services and specifically payments for ecosystem services, alongside five experiences from the Westcountry Rivers Trust (WRT), which celebrates its 30th anniversary in 2024, to demonstrate the need for integrated catchment management (ICM). It highlights the multifaceted benefits that ecosystems provide to human well-being, the challenges faced in managing these often-siloed services and the role of ICM in preserving and enhancing multiple ecosystem services, focusing on the water-related drivers of flooding, drought, water quality and aquatic biodiversity. Through WRT projects this case study highlights practical applications and successes in managing ecosystem services at the catchment level and what considerations are needed for future integration and delivery of multi-benefit solutions. This paper is derived in part from the interviews and workshops undertaken as part of the Atlantic Area Interreg funded Triple C project (EAPA_772/2018), as well as contributions from the Horizon funded, InnWater project (Horizon EUROPE No. 101036683 and UKRI No. 10066637) and the OFWAT-funded, mainstreaming Nature-based Solutions.

This article unpacks a Nahuatl metaphor based on the kin term hueltiuh, “man's elder sister,” used in multiple sixteenth-century Nahuatl texts and their Spanish derivatives. Through a minute analysis of several Nahua stories, the article identifies various roles described with this term: spies, “toothed-vagina” femmes fatales, heart-eating monsters, and seducers. Applying a method borrowed from cognitive linguistics, it then constructs a model of “man's elder sister,” which explains the application of this metaphor to different contexts. In Nahua stories, hueltiuh is usually a female mediator who throws the male characters off balance, leading to a new status quo. Confusingly, this metaphor often appears where one would expect a real kinship term and in a way that makes identifying its symbolic meaning difficult. These complications have led scholars to see (only) genealogical information in stories concerned with symbolic rather than genealogical relations between elite members or deities. The results presented here allow for refining our understanding of some famous Nahua narratives, such as the one on Topiltzin Quetzalcoatl's abandonment of Tollan. They also invite a rethinking of our views on the Nahua (Aztec) pantheon of gods, whose figurative “family bonds” may, in fact, indicate complex nonkinship relations and dependencies.

Youth living in low- and middle-income countries (LMICs) have an increased vulnerability to mental illnesses, with many lacking access to adequate treatment. There has been a growing body of interventions using task sharing with trained peer leaders to address this mental health gap. This scoping review examines the characteristics, effectiveness, components of peer delivery and challenges of peer-led mental health interventions for youth aged 10–24 in LMICs. A key term search strategy was employed across MEDLINE, Embase, Web of Science, Global Health and Global Index Medicus. Eligibility criteria included young people aged 10–24 and a peer-led component delivered in any setting in an LMIC. Study selection and extraction were conducted independently by the first and second authors, with discrepancies resolved by the senior author. Study characteristics were summarised and presented descriptively. The search identified 5,358 citations, and 19 studies were included. There were 14 quantitative, four qualitative and one mixed methods study reporting mental health outcomes. Types of interventions were heterogenous but fell within three broad categories: (1) peer education and psychoeducation, (2) peer-led psychotherapy and counselling and (3) peer support. All studies reported improved mental health outcomes as a result of the peer-led interventions. Peer-led interventions are versatile in terms of both the types of interventions and mode of delivery. Lived experience, mutual respect and reduced stigma make this method a highly unique and effective way to engage this age group. However, implementing peer-led youth interventions is not without challenges. Adequate training, supervision, cultural appropriateness and support from established institutions are critical to safeguarding and ensuring the sustainability of such programs. Our findings suggest that peer-led models are a valuable intervention strategy that policymakers can leverage in current and future efforts to address youth mental health in LMICs. Future areas of research should expand to include the perspectives of other key stakeholders involved in the implementation of peer-led mental health interventions, focusing on factors including fidelity, feasibility and acceptability to enhance implementation insights.

A new approach for constructing polar-like boundary-conforming coordinates inside a toroid with strongly shaped cross-sections is presented. A coordinate mapping is obtained through a variational approach, which involves identifying extremal points of a proposed action in the mapping space from $[0, 2{\rm \pi} ]^2 \times [0, 1]$ to a toroidal domain in $\mathbb {R}^3$. This approach employs an action built on the squared Jacobian and radial length. Extensive testing is conducted on general toroidal boundaries using a global Fourier–Zernike basis via action minimisation. The results demonstrate successful coordinate construction capable of accurately describing strongly shaped toroidal domains. The coordinate construction is successfully applied to the computation of three-dimensional magnetohydrodynamic equilibria in the GVEC code where the use of traditional coordinate construction by interpolation from the boundary failed.

Separation-related behaviours (SRBs) in dogs (Canis familiaris) often indicate poor welfare. Understanding SRB risk factors can aid prevention strategies. We investigated whether early-life experiences and dog-owner interactions affect SRB development. Using a longitudinal study, we conducted exploratory analyses of associations between potential risk factors and SRB occurrence in six month old puppies (n = 145). Dogs were less likely to develop SRBs if owners reported that, at ≤ 16 weeks old, puppies were restricted to crates/rooms overnight and had ≥ 9 h of sleep per night. Puppies with poor house-training at ≤ 16 weeks were more likely to show SRBs, as were those trained using dog treats or novel kibble versus other rewards. Puppies whose owners used more punishment/aversive techniques when responding to ‘bad’ behaviour had increased odds of SRBs at six months versus other puppies. Puppies whose owners reported ‘fussing’ over their dogs at six months in response to ‘bad’ behaviour upon their return, versus those whose owners responded in other ways, were six times more likely to display SRBs. Other factors, including dog breed, sex and source, showed no significant association with SRB occurrence. Thus, SRB development might be prevented by enabling sleep for ≥ 9 h in early life, providing enclosed space overnight, refraining from aversive training of puppies generally, and avoiding fussing over puppies in response to unwanted behaviour following separation. These recommendations derive from correlational longitudinal study results, so analysis of interventional data is required for confirmation regarding effective prevention strategies.

To evaluate the design of I-Corps@NCATS as a translational scientist training program, we mapped specific elements of the program’s content and pedagogy to the characteristics of a translational scientist, as first defined by Gilliland et al. []: systems thinker, process innovator, boundary spanner, team player, and skilled communicator. Using a mixed-methods evaluation, we examined how the I-Corps@NCATS training program, delivered across twenty-two Clinical and Translational Science Award Hubs, impacted the development of these key translational scientist characteristics.

The TRiC/CCT complex assists in the folding of approximately 10% of cytosolic proteins through an ATP-driven conformational cycle, playing a crucial role in maintaining protein homeostasis. Despite our understanding of ATP-driven TRiC ring closing and substrate folding, the process and mechanisms underlying TRiC ring-opening and substrate release remain largely unexplored. In this study, by determining an ensemble of cryo-EM structures of yeast TRiC in the presence of ADP, including three intermediate transition states, we present a comprehensive picture of the TRiC ring-opening process. During this process, CCT3 detects the loss of γ-phosphate and initiates with the dynamics of its apical protrusion, and expands to the outward leaning of the consecutive CCT6/8/7/5 subunits. This is followed by significant movements of CCT2, CCT4, and especially CCT1 subunits, resulting in the opening of the TRiC rings. We also observed an unforeseen temporary separation between the two rings in the CCT2 side, coordinating the release of the originally locked CCT4 N-terminus, which potentially participates in the ring-opening process. Collectively, our study reveals a stepwise TRiC ring-opening mechanism, provides a comprehensive view of the TRiC conformational landscape, and sheds lights on its subunit specificity in sensing nucleotide status and substrate release. Our findings deepen our understanding of protein folding assisted by TRiC and may inspire new strategies for the diagnosis and treatment of related diseases.

Recent studies suggest that value orientations, both pro-environmental values and concerns and left–right ideology, strongly predict climate policy support in some settings, but not in others, and that institutional quality determines the strength of these associations. These studies are based on a limited number of countries and do not investigate the mechanisms at work nor what aspects of quality of government (QoG) matter more specifically. Analyzing data from 135 European regions across 15 countries, this paper finds that QoG moderates the relationships of pro-environmental values and left–right ideology with climate tax support and suggests that political trust is an underlying individual-level mechanism. Moreover, corruption seems to be the most important aspect of QoG for policy support. In regions where corruption is prevalent and trust in state institutions is low, support for climate taxes is low even among those who are generally concerned about the environment and climate change and who favor state intervention. The study suggests additional analyses, adopting quantitative and qualitative approaches, to inform policymakers on how to increase public support for climate taxation and improve policy designs to mitigate policy concerns across various segments of the population.

During the COVID-19 pandemic, the European Union (EU) observed a major centralisation of competence in public health policy – the EU Vaccines Strategy. Yet increased centralisation or integration is not always desirable because the EU lacks a layer of democratic control to ensure transparency and accountability. This feature highlights the need to better understand and assess the EU’s actions during the pandemic. This paper aims to assess the effectiveness of the EU Vaccines Strategy and contributes to the wider debate on the centralisation of power at Union level. The joint procurement of COVID-19 vaccines is considered a success, as it avoided a “vaccine scramble” by the EU Member States. However, the fact that the Member States were obliged to purchase more than they needed and the lack of transparency in the negotiations with companies on the procurement of vaccines have raised questions about the integrity of the Commission’s exercise of executive power.

This systematic review and meta-analysis explore the correlation between foreign language instruction and mathematical skills in young adolescents, highlighting the significance of high school mathematical education and the adaptability of the adolescent brain. Focused on students starting second language programs between ages 8 and 13, following PRISMA guidelines, this review included 25 studies (1978–2020) with 785,552 participants. Using a random-effects model, the overall effect size revealed a statistically significant relationship between our variables, indicating a threefold higher likelihood of passing or achieving higher grades in mathematical tests for language-learning students. Moderating variables analyses identified socioeconomic status (SES) and intervention length as influencers of observed heterogeneity, with SES being the primary factor. Sensitivity analyses, including adding potentially missing studies and removing outliers, confirmed the robustness of the overall effect. Nonetheless, additional research is needed to enhance global diversity and comprehensively understand the interplay between language learning and cognitive function.

On March 15, 2024, the Corporate Sustainability Due Diligence Directive (CSDDD or Directive) was adopted by the EU Council.1 This Directive represents the EU's first piece of mandatory due diligence legislation governing the responsibilities of companies for human rights due diligence and transition plans for climate mitigation. It also codifies the principle that “all businesses have a responsibility to respect human rights, which are universal, indivisible, interdependent and interrelated.”2 The Directive broadly follows the framework of the non-binding UN Guiding Principles on Business and Human Rights (UNGPs) which first introduced the concept of human rights due diligence.3 The CSDDD requires that businesses incorporate human rights due diligence into policies,4 identifying, assessing, preventing, mitigating, and ending actual and potential adverse human rights impacts,5 remedying any impacts and monitoring the effectiveness of these processes.6 The Directive also introduces significant sanctions for non-compliance.7

This study investigates Navajo verbs produced by four children, ages 4;07 to 11;02, during conversations with their caretakers. Analyses of 1600 verbs demonstrate that the bisyllabic verb form, consisting of a verb stem and a portion of the prefix string, is the most common pattern produced by the children. This indicates that Navajo-speaking children use meaningful units of verbal morphology that do not necessarily adhere to the linguistic boundaries normally ascribed to the Navajo verb complex. Further, the verbs are primarily intransitive and third-person singular constructions, which are minimally inflected. It is argued that these minimally-inflected verb forms are frequent not just because they are simpler, but also because they are highly productive as main verbs and are used to create phrasal verbs and nouns. These findings contribute to our general understanding of language development and to the growing body of research investigating children’s acquisition of endangered Indigenous languages.

This study demonstrates a kilowatt-level, spectrum-programmable, multi-wavelength fiber laser (MWFL) with wavelength, interval and intensity tunability. The central wavelength tuning range is 1060–1095 nm and the tunable number is controllable from 1 to 5. The wavelength interval can be tuned from 6 to 32 nm and the intensity of each channel can be adjusted independently. Maximum output power up to approximately 1100 W has been achieved by master oscillator power amplifier structures. We also investigate the wavelength evolution experimentally considering the difference of gain competition, which may give a primary reference for kW-level high-power MWFL spectral manipulation. To the best of our knowledge, this is the highest output power ever reported for a programmable MWFL. Benefiting from its high power and flexible spectral manipulability, the proposed MWFL has great potential in versatile applications such as nonlinear frequency conversion and spectroscopy.

Research by the Tlalancaleca Archaeological Project (PATP) has corroborated modifications to the Middle Formative chronology in Puebla-Tlaxcala (Lesure et al. 2006, 2014) using Bayesian modeling on 26 radiocarbon dates from Tlalancaleca. The present study is the first to evaluate the region’s Middle Formative chronology with radiocarbon dates from superposed stratigraphy. Nine Bayesian models were constructed with different combinations of radiocarbon dates and OxCal’s phase and sequence functions to determine the beginning and end of the Texoloc phase. Results place the Tlatempa-Texoloc transition at around 650 cal BC and the Texoloc-Tezoquipan transition at around 500 cal BC. The OxCal Interval function supports a timespan of approximately 150 years for the duration of the Texoloc phase. These results suggest the process of initial urbanization in Central Mexico was a rapid one.

The study explored the origin of the age of acquisition (AoA) effect in second language (L2) using ERPs technique. We simulated L2 AoA by manipulating the order at which English pseudowords entered into training. Chinese-English bilinguals (mean age 22.04, range 18–28) learned English pseudowords matched with Chinese (L1) words, investigating the order of acquisition (OoA) effect of English pseudowords and its relationship with the matched L1 words’ AoA. OoA effects were observed in lexical decision, naming and semantic judgment tasks on N170, P200 and N400. Furthermore, OoA effects were modulated by L1 AoA in the semantic judgment task. These results suggested that OoA effects were independent at orthographic and phonological levels but modulated by L1 AoA at the semantic level. The interpretation of L2 AoA effects requires not only the integration of Semantic and Arbitrary Mapping Hypotheses, as well as consideration of the representation and activation characteristics of L2 words.

The received view is that Kant denies all moral luck. But I show how Kant affirms constitutive moral luck in passages concerning radical evil from Religion within the Boundaries of Mere Reason. First, I explicate Kant’s claims about radical evil. It is a morally evil disposition that all human beings have necessarily, at least for the first part of their lives, and for which they are blameworthy. Second, since these properties about radical evil appear to contradict Kant’s even more famous claims about imputation, ‘ought implies can’, and free will, I unpack Henry Allison’s proof of radical evil and show how it is consistent with interpretations of Kant’s broader views about morality. Third, I define and illustrate the category of constitutive moral luck and argue that Kant embraces the existence of constitutive moral luck given Allison-style interpretations of radical evil. This provides a reason for philosophers to reject the received view, and it creates an occasion for Kantians and Kant scholars to check their reasons if they deny moral luck.