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This study aimed to determine if a history of tinnitus is associated with the risk of developing dementia.
Method
A nationwide population-based case–control study including all eligible adults in Taiwan.
Results
A total of 15 686 patients were included in the study, with 7843 individuals making up each of the case and control groups. Patients with a history of tinnitus were associated with a statistically significant higher risk of being diagnosed with dementia before reaching 65 years old (50 years ≤ age <65 years) (adjusted odds ratio 2.68, 95 per cent confidence interval (CI) 1.19–6.05, p = 0.017). No statistical significance was found among those 65 years and older (adjusted odds ratio 1.17, 95 per cent CI 0.90–1.51, p = 0.235).
Conclusion
A history of tinnitus was associated with a 168 per cent increased risk of being diagnosed with dementia in those aged 50–65 years old. This association was not significant in those older than 65 years.
Sediments within accretionary complexes, preserving key information on crust growth history of Central Asian Orogenic Belt, did not get enough attention previously. Here, we conduct comprehensive geochemical study on the turbidites from the North Tianshan Accretionary Complex (NTAC) in the Chinese West Tianshan orogen, which is a good example of sediments derived from juvenile materials. The turbidites, composed of sandstone, siltstone, and argillaceous siliceous rocks, are mainly Carboniferous. All the investigated samples have relatively low Chemical Index of Alteration values (35–63) and Plagioclase Index of Alteration values (34–68), indicating relatively weak weathering before erosion and deposition. The sandstone and siltstone, and slate samples display high Index of Compositional Variability values of 0.89–1.50 and 0.89–0.93, suggesting a relatively immature source. The sandstones and siltstones were mainly derived from intermediate igneous rocks, and the slates from felsic igneous rocks, formed in oceanic/continental arc settings. The investigated samples roughly display high positive εNd(t) values (mainly at +5.5 to +7.9, except one spot at +0.8), with corresponding Nd model ages at 672 Ma–522 Ma (except one at ∼1.1 Ga). Combined with the previous studies, we suggest that the turbidites in the NTAC were mainly derived from intermediate to felsic igneous rocks with juvenile arc signature, and thus the northern Chinese West Tianshan is a typical site with significant Phanerozoic crust growth.
The 2022 Russian invasion of Ukraine raised for many parties the question of how to position themselves in view of urgently requested arms deliveries. Since, the topic of arms trade, which has hitherto rarely been addressed, has become a heavily politicized and divisive issue and partly even polarized public opinion. A major prerequisite for parties’ position-taking is to anticipate how voters react to such arms transfers and, more specifically, whether their respective attitudes are structured along the predominant left-right axis. Based on a large-scale survey experiment with French and German voters ($N = 6617$) in the year before the Russian invasion, we are able to focus on the relationship between ideological predispositions, vote intentions, and issue attitudes in a non-politicized period. Using both vignette and conjoint experiments, we demonstrate that voters’ attitudes on military transfers can be subsumed remarkably well under the left-right scale. Differentiating the impact of normative and economic considerations, the former is stronger among the left, while the latter also affects the attitudes of rightist citizens. However, normative considerations are the most important concern along the whole political spectrum. The turn of the German Green Party in 2022 to assist countries that are being aggressively attacked (because of the Responsibility to Protect), was not reflected in our data.
To define the amount, thermal maturity and type of organic matter (OM), a comprehensive analysis of major and trace elements, organic carbon isotope and organic geochemistry was conducted on Lutetian black shales found in the Everek (Bayburt) region of northeastern Turkey. Total organic carbon (TOC) levels in the shale samples range from 0.62% to 6.75%, and type II–III to type III kerogen is generated, displaying a combination of high terrigenous and low marine OM. The δ13C values (ranging from –28.22‰ to –28.23‰), aromatic hydrocarbon compounds (methyl phenanthrene, dibenzothiophene, tri-aromatic and monoaromatic steroids), saturated hydrocarbon compounds (sterane and terpane), acyclic isoprenoids, n-alkane distribution (n-C13–n-C36) and inorganic geochemical characterization support that the black shales were deposited in a terrestrial-marine transition environment and had a high proportion of terrestrial OM with small amounts of marine OM preserved in relatively arid to hot climate and oxic to suboxic conditions. The analysis of biomarker thermal maturity markers, Tmax (ranging from 449–458 oC) and estimated vitrinite reflectance (varying from 0.92 to 1.08%) values suggest that the black shales have reached the oil window. As a result, black shales are thought to contain low to high amounts of TOC, have a mixed kerogen type, reach a high thermal maturity level and produce little hydrocarbons.
This paper provides the methodology used to simulate and control an icosahedral tensegrity structure augmented with movable masses attached to each bar to provide a means of locomotion. The center of mass of the system can be changed by moving the masses along the length of each of the bars that compose the structure. Moving the masses changes the moments created by gravitational force, allowing for the structure to roll. With this methodology in mind, a controller was created to move the masses to the desired locations to cause such a roll. As shown later in this paper, such a methodology, assuming the movable masses have the required mass, allows for full control of the system using a quasi-static controller created specifically for this system. This system has advantages over traditional tensegrity controllers because it retains its shape and is designed for high-shock scenarios.
We present deep near-infrared $K_\textrm{s}$-band imaging for 35 of the 53 sources from the high-redshift ($z \gt 2$) radio galaxy candidate sample defined in Broderick et al. (2022, PASA, 39, e061). These images were obtained using the High-Acuity Widefield K-band Imager (HAWK-I) on the Very Large Telescope. Host galaxies are detected for 27 of the sources, with $K_\textrm{s} \approx 21.6$–23.0 mag (2$^{\prime\prime}$ diameter apertures; AB). The remaining eight targets are not detected to a median $3\unicode{x03C3}$ depth of $K_\textrm{s} \approx 23.3$ mag (2$^{\prime\prime}$ diameter apertures). We examine the radio and near-infrared flux densities of the 35 sources, comparing them to the known $z \gt 3$ powerful radio galaxies with 500-MHz radio luminosities $L_{500\,\textrm{MHz}} \gt 10^{27}$ W Hz$^{-1}$. By plotting 150-MHz flux density versus $K_\textrm{s}$-band flux density, we find that, similar to the sources from the literature, these new targets have large radio to near-infrared flux density ratios, but extending the distribution to fainter flux densities. Five of the eight HAWK-I deep non-detections have a median $3\unicode{x03C3}$ lower limit of $K_\textrm{s} \gtrsim 23.8$ mag (1$.\!^{\prime\prime}$5 diameter apertures); these five targets, along with a further source from Broderick et al. (2022, PASA, 39, e061) with a deep non-detection ($K_\textrm{s} \gtrsim 23.7$ mag; $3\unicode{x03C3}$; 2$^{\prime\prime}$ diameter aperture) in the Southern H-ATLAS Regions $K_\textrm{s}$-band Survey, are considered candidates to be ultra-high-redshift ($z \gt 5$) radio galaxies. The extreme radio to near-infrared flux density ratios ($\gt 10^5$) for these six sources are comparable to TN J0924$-$2201, GLEAM J0856$+$0223 and TGSS J1530$+$1049, the three known powerful radio galaxies at $z \gt 5$. For a selection of galaxy templates with different stellar masses, we show that $z \gtrsim 4.2$ is a plausible scenario for our ultra-high-redshift candidates if the stellar mass $M_\textrm{*} \gtrsim 10^{10.5}$ M$_\odot$. In general, the 35 targets studied have properties consistent with the previously known class of infrared-faint radio sources. We also discuss the prospects for finding more UHzRG candidates from wide and deep near-infrared surveys.
I investigate why some countries were more successful in containing the death toll than others during the COVID-19 pandemic. I focus on the role of socialism and on the existence of long-term regime-driven legacies that may have had an impact on the containment of COVID-related deaths. I claim that countries that went through successful socialist revolutions have specific features that equip them with better resources to cope with public challenges such as pandemics. Furthermore, these features remain even after the demise of the socialist regime. I find a positive effect of socialist revolutions over COVID-19 containment at the country level. I investigate three possible causal mechanisms for this relationship: authoritarianism, state capacity, and mass mobilization. Through mediation analysis, I find the socialist legacy seems to be channeled through higher levels of mobilization and also more authoritarian institutions.
We derive and analyse well-posed boundary conditions for the linear shallow water wave equation. The analysis is based on the energy method and it identifies the number, location and form of the boundary conditions so that the initial boundary value problem is well-posed. A finite-volume method is developed based on the summation-by-parts framework with the boundary conditions implemented weakly using penalties. Stability is proven by deriving a discrete energy estimate analogous to the continuous estimate. The continuous and discrete analysis covers all flow regimes. Numerical experiments are presented verifying the analysis.
Phonological processes tend to involve local dependencies, an observation that has been expressed explicitly or implicitly in many phonological theories, such as the use of minimal symbols in SPE and the inclusion of primarily strictly local constraints in Optimality Theory. I propose a learning-based account of local phonological processes, providing an explicit computational model. The model is grounded in experimental results that suggest children are initially insensitive to long-distance dependencies and that as their ability to track non-adjacent dependencies grows, learners still prefer local generalisations to non-local ones. The model encodes these results by constructing phonological processes starting around an alternating segment and expanding outward to incorporate more phonological context only when surface forms cannot be predicted with sufficient accuracy. The model successfully constructs local phonological generalisations and exhibits the same preference for local patterns that humans do, suggesting that locality can emerge as a computational consequence of a simple learning procedure.
This article analyses the endogenous choice of farmers to be organic or conventional in a groundwater evolutionary model when a tax on fertiliser on conventional farmers is implemented by a regulatory agency. The analysis of the model shows that the coexistence of both type of farmers only occurs when the decrease in productivity due to organic production is relatively low and the price premium for organic products is relatively high. However, even if conversion is welfare improving, our results show that this conversion may be done at the expense of the water resource with a lower water table. An application to the Western la Mancha aquifer (Spain) illustrates the main results.
A previous paper of the authors (Duck & Stephen, J. Fluid Mech., vol. 917, 2021, A56) considered the effect of three-dimensional, temporally periodic, linear and incompressible disturbances on a Blasius boundary layer, in particular when the disturbance wavelength is both comparable to and longer than the boundary-layer thickness. This previous study revealed that, unlike the two-dimensional counterpart, a mode exists that exhibits regimes of downstream spatial growth. In this paper we extend the analysis to the compressible regime, based on the boundary-region equations methodology. The aforementioned unstable mode is seen to persist into the compressible regime, and is studied using a combination of numerical and asymptotic methods. The paper adopts several approaches. First is a numerical approach in which the spatial development of the disturbances is assessed. This then leads to a consideration of the far-downstream behaviour, using (several) asymptotic limits. Of some note, in addition to unstable modes found in the incompressible case, is the existence of a further class of instability, not found in the incompressible case (which is also analysed asymptotically), corresponding to what amounts to an inviscid instability. The far-downstream analysis enables a (sub-)classification into entropy and non-entropy modes. The former, according to this analysis, are spatially damped, with one caveat, as revealed by our marching procedure, which highlights how spatial development of disturbances can be important.
This article investigates dictionary usage with Year 7 students of Latin. During my lesson observations I noticed how much students relied on looking up words in the dictionary when working on translation from Latin to English. I wanted to find out if there was the potential for a more interactive and/or memorable way for students to work with their dictionaries. This action research project was carried out in an all-boys, secondary, selective school. I noticed that when students were set to work on translation from Latin to English, they spent a significant amount of time looking up words in the dictionary at the back of the booklet. Often by the time they had looked up the word in question and then turned back to the translation, they had already forgotten the meaning of the word they had looked up. Additionally, the words they were looking for were words that they had already encountered several times but forgotten the meaning of since the last time they had looked it up or seen it. The research confirmed that merely copying the words that students looked up down multiple times helped them recall the vocabulary better than if they simply looked the words up.
(1) To develop a new regression equation for estimating fat mass percentage (%FM) from anthropometric measurements in a heterogeneous Caucasian population and (2) to compare it with the Durnin and Womersley equation, which is one of the most used anthropometric equations for FM assessment.
Design:
Body mass, stature and four skinfolds (biceps, triceps, subscapular and supracrestal) were assessed by an accredited anthropometrist, according to the International Society for Advancement in Kinanthropometry. Participants completed a dual-energy X-ray absorptiometry (DXA) whole-body scan to determine their %FM. A new anthropometric equation to estimate %FM was developed using multiple forward regression analyses with DXA as the reference method. Tests for the accuracy of the different equations included mean differences, coefficient of determination, SE of the estimate (SEE), concordance correlation coefficient (CCC) and Bland–Altman plots.
Setting:
Spain.
Participants:
Two hundred and eighteen healthy Caucasian participants aged 18–65 years participated in this cross-sectional study.
Results:
Our proposed equation explained 89·9 % of the variance in the DXA-derived %FM, with a low random error (SEE = 3·00 %), a very strong agreement (CCC = 0·93), no fixed or proportional bias and a relatively low individual variability (5·84 %). However, the Durnin and Womersley equations obtained a fixed bias of –3·65 % when compared with DXA and a greater individual variability (6·74 %).
Conclusions:
The proposed equation can accurately estimate %FM in a heterogeneous Caucasian population with a wide age range (18–65 years). Additionally, the Durnin and Womersley equation was inadequate when applied to our participants.
Control over the legislative messaging agenda has important political, electoral and policy consequences. Existing models of congressional agenda-setting suggest that national polarization drives the agenda. At the same time, models of home style and formal models of leadership hypothesize that legislators shift their messaging as they balance coordination and information problems. We say the coordination problem dominates when conditions incentivize legislators to agree on the same message rather than fail to reach consensus. Conversely, the information problem is said to dominate in circumstances where legislators prefer to say nothing at all rather than reach consensus on the wrong political message. Formal theories predict that when coordination problems are pressing, legislative members follow the policy positions of party leaders. When their party’s information problem is acute, party members instead rely on the wisdom of the caucus to set the party’s agenda. To test these theories, we analyze the Twitter accounts of U.S. House members with a Joint Sentiment Topic model, generating a new understanding of House leadership power. Our analyses reveal complex leader-follower relationships. Party leaders possess the power to substantially affect the propensity of rank-and-file members to discuss topics, especially when the coordination problem dominates; these effects are pronounced even when coordination problems are pressing. That said, when the underlying politics are unclear, rank-and-file members exert influence on the discussion of a topic because the information problem is more acute. At the same time and for these uncertain topics, leadership influence decreases, consistent with theory. We show these results are robust to the underlying dynamics of contemporary political discussion and context, including leading explanations for party leadership power, such as national polarization.
Game riskiness is an index to describe the variance of outcomes of choosing cooperation relative to that of choosing defection in prisoner’s dilemmas (PD). When the variance of cooperation is larger (smaller) than that of defection, the PD is labeled as a more-risky PD (less-risky PD). This article extends the previous work on game riskiness by examining its moderating role on the effect of expectation on cooperation under various PDs. We found across three studies that game riskiness moderated the effect of expectation on cooperation such that the effect of expectation on cooperation was larger in more-risky PDs than in less-risky counterparts. This effect was observed in N-person PD (Study 1), PD presented in both gain and loss domains (Study 2), and PD where expectation was manipulated instead of measured (Study 3). Furthermore, we found that participants cooperated more in PDs presented in the gain domain compared to those presented in the loss domain, and this effect was again moderated by game riskiness. In addition, we illustrated mathematically that game riskiness is related to other established indices of PD, including the index of cooperation, fear index, and greed index. This article identified game riskiness as a robust situational factor that can impact decisions in social dilemmas. It also provided insights into the underlying motivations of cooperation and defection under different expectations and how game riskiness can be utilized in cooperation research.
Migrants and refugees face elevated risks for mental health problems but have limited access to services. This study compared two strategies for training and supervising nonspecialists to deliver a scalable psychological intervention, Group Problem Management Plus (gPM+), in northern Colombia. Adult women who reported elevated psychological distress and functional impairment were randomized to receive gPM+ delivered by nonspecialists who received training and supervision by: 1) a psychologist (specialized technical support); or 2) a nonspecialist who had been trained as a trainer/supervisor (nonspecialized technical support). We examined effectiveness and implementation outcomes using a mixed-methods approach. Thirteen nonspecialists were trained as gPM+ facilitators and three were trained-as-trainers. We enrolled 128 women to participate in gPM+ across the two conditions. Intervention attendance was higher in the specialized technical support condition. The nonspecialized technical support condition demonstrated higher fidelity to gPM+ and lower cost of implementation. Other indicators of effectiveness, adoption and implementation were comparable between the two implementation strategies. These results suggest it is feasible to implement mental health interventions, like gPM+, using lower-resource, community-embedded task sharing models, while maintaining safety and fidelity. Further evidence from fully powered trials is needed to make definitive conclusions about the relative cost of these implementation strategies.
The European Legal order, created by the European Court of Justice [ECJ], is an astonishingly effective treaty enforcement system. Previous explanations of its ‘transnational’ or ‘constitutional’ development have focused on the politics of judicial networks, and the wider political and economic context of postwar European democracy. Judicial biography has been almost entirely overlooked, even in the case of Robert Lecourt, widely acknowledged as the leading judge in the Court’s revolutionary period. Unknown to research on the ECJ, however, Lecourt had already spearheaded the adoption of the famous Article 49-3 of France’s 1958 Constitution. This paper demonstrates that the constitutional doctrines of European law and Article 49-3 were in fact premised on a similar ideology, that the pursuit of ‘effectiveness’ may require unprecedented restrictions on the traditional law-making role of national parliaments. Those were the constitutional values of the judge that, more than any other, built the foundations of the European legal order.
The goals of this investigation were to 1) identify and measure exposures inside homes of individuals with chemical intolerance (CI), 2) provide guidance for reducing these exposures, and 3) determine whether our environmental house calls (EHCs) intervention could reduce both symptoms and measured levels of indoor air contaminants.
Background:
CI is an international public health and clinical concern, but few resources are available to address patients’ often disabling symptoms. Numerous studies show that levels of indoor air pollutants can be two to five (or more) times higher than outdoor levels. Fragranced consumer products, including cleaning supplies, air fresheners, and personal care products, are symptom triggers commonly reported by susceptible individuals.
Methods:
A team of professionals trained and led by a physician/industrial hygienist and a certified indoor air quality specialist conducted a series of 5 structured EHCs in 37 homes of patients reporting CI.
Results:
We report three case studies demonstrating that an appropriately structured home intervention can teach occupants how to reduce indoor air exposures and associated symptoms. Symptom improvement, documented using the Quick Environmental Exposure and Sensitivity Inventory Symptom Star, corresponded with the reduction of indoor air volatile organic compounds, most notably fragrances. These results provide a deeper dive into 3 of the 37 cases described previously in Perales et al. (2022).
Discussion:
We address the long-standing dilemma that worldwide reports of fragrance sensitivity have not previously been confirmed by human or animal challenge studies. Our ancient immune systems’ ‘first responders’, mast cells, which evolved 500 million years ago, can be sensitized by synthetic organic chemicals whose production and use have grown exponentially since World War II. We propose that these chemicals, which include now-ubiquitous fragrances, trigger mast cell degranulation and inflammatory mediator release in the olfactory-limbic tract, thus altering cerebral blood flow and impairing mood, memory, and concentration (often referred to as ‘brain fog’). The time has come to translate these research findings into clinical and public health practice.
The impact of shoaling on linear water waves is well known, but it has only been recently found to significantly amplify both the intensity and frequency of rogue waves in nonlinear irregular wave trains atop coastal shoals. At least qualitatively, this effect has been partially attributed to the ‘rapid’ nature of the shoaling process, i.e. shoaling occurs over a distance far shorter than that required for waves to modulate themselves and adapt to the reduced water depth. Through a theoretical model and highly accurate nonlinear simulations, we disentangle the respective effects of the length and angle of a shoal's slope. We investigate the effects of the shoaling process rapidness on the evolution of key statistical and spectral sea-state parameters. We let the wave field evolve over a slope with constant angle in all cases while we vary the slope length. Our results indicate that the non-equilibrium dynamics is not affected by the slope length, because further extending the slope length does not influence the magnitude of the statistical and spectral measures as long as the non-equilibrium dynamics dominates the wave evolution. Thus, the shoaling effect on rogue waves is deduced to be mainly driven by the slope magnitude rather than the slope length.
The aim of this study is to conduct a comparative analysis across nations to: (1) identify the determinants influencing knowledge and attitudes related to sodium (Na) intake and (2) to analyse the association between knowledge and attitudes related to Na intake.
Design:
We utilised a secondary data from a cross-sectional study that was conducted across seven nations. Structural equation modelling (SEM) was utilised to assess the impact of socio-economic and health-related predictors on knowledge and attitudes pertaining to Na intake and further to investigate the relationship between knowledge and attitude.
Setting:
Indonesia, Brazil, Thailand, Japan, France, the UK and the USA.
Participants:
7090 participants aged 15 years and above were included in the study.
Results:
SEM analysis showed a strong association between knowledge about Na intake and related attitude across all countries, particularly in the UK (2·65, 95 % CI 1·48–3·82), France (2·62, 1·45–3·79) and the USA (1·97, 1·21–2·73). In Brazil, Japan and France, individuals or family members having certain health conditions such as raised blood pressure, heart diseases, strokes or other diseases exhibited a positive attitude towards reducing Na intake. Conversely, socio-economic factors like education and income demonstrated the complexity of influences on knowledge and attitudes about Na intake.
Conclusion:
The study underscores the need for tailored public health interventions to reduce excessive Na consumption, considering the diverse cultural, social and economic factors. It highlights the complex determinants of knowledge and attitudes towards Na intake, calling for further research in varied populations.