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There is a consensus in the literature that the Marxism of the Second International (1889–1916) lacked philosophical sophistication and that understanding of Marxism’s Hegelian origins was lost soon after Karl Marx’s death, only to be recovered with the emergence of Western Marxism in the 1920s. This article challenges this consensus, urging revision of the basic outlines of the intellectual history of Marxism. It begins by sketching two ways contemporary scholars understand the Hegel-Marx connection. It then shows that these views were anticipated before World War I in the work of Max Adler. Against the view that Hegel was “put back into Marxism” in the 1920s or 1970s, then, this article maintains that there have always been sophisticated as well as simplifying accounts of the Hegel-Marx connection.
Ensuring easy access to clean and safe drinking water using low-cost technology is essential to mitigate the rising water scarcity in emerging economies. Commercial large-scale desalination technologies need significant investment, making them unsuitable for off-grid and small-scale applications. However, this operation can be carried out using a low-cost desalination technology based on renewable energy, known as the solar still. In this research work, a modified basin solar still (basin solar still + internal mirrors + 8 kg gravel + black ink (400 ppm per litre)) was developed and experimentally tested in Visakhapatnam (17.68°N, 83.22°E), India, to determine its appropriateness for sustainable seawater desalination. It produced 14% to 23% more desalinated water than a conventional basin solar still. In addition, its thermal efficiency was between 41% and 42%, which was significantly greater than other basin solar stills reported in literature. In addition, high-quality desalinated water was generated at a cost that was around three times less than the drinking water offered at Indian Railways kiosks. Moreover, the ability to mitigate significant CO2 emissions while also addressing water scarcity demonstrated that the modified basin solar still continues to contribute effectively to the United Nations Sustainable Development Goal 6 (Clean Water and Sanitation).
Recent decades have seen a steady increase in antidepressant prescribing, but little is known about prescribing trends during and following the COVID-19 pandemic.
Aims
This preregistered systematic review, following Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines, aimed to investigate antidepressant prescribing trends for adults in the UK and Republic of Ireland during and after the pandemic. It also compared prescriptions by drug and location.
Method
We searched six databases: APA PsycInfo, CINAHL, MEDLINE, Scopus, medRxiv and Preprints.org. The review included primary research articles reporting trends in antidepressant prescriptions, including at least one time point after March 2020 in the UK and Republic of Ireland. This review has been preregistered on PROSPERO (ID: CRD42024498503).
Results
We identified 7,320 studies, of which ten met the search criteria for the review. Studies were grouped on the basis of time period (2020: n = 5; 2021: n = 3; 2022: n = 2), location (England, Scotland, Northern Ireland, Republic of Ireland, UK) and drug type (serotonin–noradrenaline reuptake inhibitors, selective serotonin reuptake inhibitors, tricyclics, and others (e.g. monoamine oxidase inhibitors)). Most studies (eight of ten) demonstrated increased antidepressant prescribing over time. Two studies highlighted a decrease between March and May 2020. Demographic variables reflected higher rates of prescribing for women, and the modal group receiving antidepressants comprised middle-aged adults.
Conclusions
The commonly reported increase in antidepressant prescribing corroborates pre-pandemic trends and may suggest further, increased demands for mental health support to meet the unique challenges of the pandemic. Future research is required to evaluate the appropriateness of treatment decisions and to explore psychosocial factors that influence individual prescribing choices.
While much scholarship has considered the role of racial attitudes in shaping public opinion, this paper extends this line of research by examining how racial resentment influences voter turnout and further, how this effect differs across religious and racial groups. Building on conflict decision theory and theories of racialized social pressure, the paper develops expectations about the conditional influence of racial attitudes on voter participation, depending on these compounding religious and racial identities. Analysis of the 2020 Collaborative Multiracial Post-Election Survey (CMPS) reveals that racial resentment is associated with higher voter turnout among White evangelicals, Asian American evangelicals, and Latino evangelicals, while having no impact on White, Latino, and Asian Americans who do not identify as evangelical. In contrast, holding more conservative racial attitudes is associated with a lower, rather than higher, likelihood of voting among both Black evangelicals and Black non-evangelicals. The paper concludes by underscoring the need to examine how multiple social identities can structure the factors that influence political decision-making in American politics.
After a brief overview of tardive dyskinesia, this targeted narrative review will examine the psychosocial consequences of tardive dyskinesia on patients’ daily lives, including stigma, social withdrawal, and quality of life, as well as impact on physical functioning. The extant literature on the impact of tardive dyskinesia on patients and their caregivers is described and summarized, including how patients with tardive dyskinesia perceive the severity and impact of their motor symptoms and whether this aligns with clinical observations by their treaters.
Building energy management (BEM) tasks require processing and learning from a variety of time-series data. Existing solutions rely on bespoke task- and data-specific models to perform these tasks, limiting their broader applicability. Inspired by the transformative success of Large Language Models (LLMs), Time-Series Foundation Models (TSFMs), trained on diverse datasets, have the potential to change this. Were TSFMs to achieve a level of generalizability across tasks and contexts akin to LLMs, they could fundamentally address the scalability challenges pervasive in BEM. To understand where they stand today, we evaluate TSFMs across four dimensions: (1) generalizability in zero-shot univariate forecasting, (2) forecasting with covariates for thermal behavior modeling, (3) zero-shot representation learning for classification tasks, and (4) robustness to performance metrics and varying operational conditions. Our results reveal that TSFMs exhibit limited generalizability, performing only marginally better than statistical models on unseen datasets and modalities for univariate forecasting. Similarly, inclusion of covariates in TSFMs does not yield performance improvements, and their performance remains inferior to conventional models that utilize covariates. While TSFMs generate effective zero-shot representations for downstream classification tasks, they may remain inferior to statistical models in forecasting when statistical models perform test-time fitting. Moreover, TSFMs’ forecasting performance is sensitive to evaluation metrics, and they struggle in more complex building environments compared to statistical models. These findings underscore the need for targeted advancements in TSFM design, particularly their handling of covariates and incorporating context and temporal dynamics into prediction mechanisms, to develop more adaptable and scalable solutions for BEM.
We study the generalised Chvátal–Sankoff constant $\gamma _{k,d}$, which represents the normalised expected length of the longest common subsequence of d independent uniformly random strings over an alphabet of size k. We derive asymptotically tight bounds for $\gamma _{2,d}$, establishing that $\gamma _{2,d} = \tfrac 12 + \Theta ({1}/{\sqrt {d}})$. We also derive asymptotically near-optimal bounds on $\gamma _{k,d}$ for $d\ge \Omega (\log k)$.
Poverty is associated with the severity of common mental health disorders and increased physical comorbidities. However, its effects on severe mental illness (SMI), beyond increasing their incidence, are less understood, especially in low- and middle-income countries. We here examined the relationship between baseline household income and subsequent mental and physical health outcomes in a large cohort of individuals diagnosed with schizophrenia or bipolar disorder in Colombia.
Methods
Retrospective cohort and case–control study using electronic health records from over 5 million Colombians. We identified individuals diagnosed with schizophrenia or bipolar disorder and their baseline household income. Mental health outcomes included third-line antipsychotic treatments (clozapine or antipsychotic polypharmacy) and psychiatric hospitalizations. Physical outcomes included diagnoses of hypertension, type 2 diabetes, and HbA1c levels, compared with rates in individuals without SMI.
Results
We included 12,216 (6,485 women) participants newly diagnosed with bipolar disorder or schizophrenia between 2019 and 2023. Compared to middle-income participants (between $700–1,750USD/month), patients on a low income (less than $700USD/month) were more likely to require third-line antipsychotic treatment (OR 1.84 [1.64, 2.08]) and psychiatric hospitalization (incidence rate ratio 1.30 [1.21, 1.41]). Low-income participants with SMI had hypertension and diabetes rates like middle-income participants without SMI who were 20 years older. However, the combined effect of SMI and low income together posed a less-than-additive risk. Lower income was associated with higher HbA1c levels in diabetes, while a diagnosis of SMI was associated with lower levels.
Conclusions
Low income at SMI onset is associated with worse mental and physical health outcomes.
Treatment non-adherence is a well-established predictor of relapse in schizophrenia, yet its broader clinical impact remains unclear. This study examines the association between clinician-recorded treatment non-adherence and clinical outcomes during the first year following a schizophrenia diagnosis. Using a bespoke natural language processing algorithm applied to anonymised electronic health records, we classified the recorded treatment adherence status of 2667 patients. Multivariable and Poisson regression analyses were conducted to assess associations of recorded treatment non-adherence with clinical outcomes.
Results
Compared with the remainder, those classified as non-adherent had greater increases in recorded symptoms and higher frequency and duration of in-patient admissions and crisis care episodes. They were also prescribed a greater number of different antipsychotics and developed a greater number of recorded physical health comorbidities.
Clinical implications
Treatment non-adherence is associated with markedly poorer clinical outcomes, emphasising the importance of early identification and targeted interventions to support adherence.
Public health data modernization in the United States has accelerated since COVID-19 exposed systemic weaknesses in fragmented data infrastructure and governance. Technical solutions have advanced, but legal and relational barriers still complicate data sharing across jurisdictions. Traditionally, interjurisdictional data sharing has relied on individually negotiated Data Use Agreements (DUAs), a process that is both resource-heavy and often opaque. To address this, the Centers for Disease Control and Prevention have proposed a Core DUA to standardize terms and reduce administrative burden. However, its success depends on trust — a fragile foundation increasingly strained by politicization, perceived lack of transparency, and controversial federal actions involving sensitive data. Jurisdictional concerns about compliance, security, and misuse underscore the need for governance frameworks that prioritize clarity, reciprocity, and accountability. Coercive approaches risk deepening fragmentation and undermining collaborative governance. Ultimately, modernization efforts will fail without supporting trust as the cornerstone of public health data governance. This article examines legal variation, transactional friction, and evolving jurisdictional perspectives to illuminate the critical role of trust in shaping the future of public health data systems.
The United Kingdom’s Talking Therapies for Anxiety and Depression (TTAD) programme provides standardised definitions for recovery-related outcomes, allowing transparent and comparable reporting. This study aimed to descriptively examine recovery-related outcomes following cognitive behavioural therapy (CBT) in a Japanese clinical sample using established TTAD definitions.
Method:
Data were drawn from patients who received CBT in routine clinical practice. Depressive and anxiety symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9) and the Generalized Anxiety Disorder-7 (GAD-7) questionnaire, respectively. Recovery, reliable improvement, and reliable recovery were classified according to the TTAD criteria.
Results:
The sample consisted of 241 participants, of whom 178 (73.9%) met the criteria for caseness at baseline. Among those with baseline caseness, 75 participants (42.1%) met the criteria for recovery at the end of treatment. Across the full sample, 103 participants (47.2%) demonstrated reliable improvement. Reliable recovery, defined as meeting the criteria for both recovery and reliable improvement, was observed in 65 participants (36.5% of those with baseline caseness).
Conclusions:
Using standardised TTAD definitions, this study provides a descriptive account of recovery-related outcomes following CBT in routine clinical practice in Japan. The findings show the distribution of recovery and improvement outcomes in this sample and highlight the importance of clearly distinguishing between recovery-related indicators when interpreting outcomes in real-world clinical settings.
Despite its significant impact on parenting and child outcomes, postnatal anxiety receives less attention than postnatal depression. Intolerance of uncertainty (IU) and inflated responsibility (IR) may be vulnerability factors for postnatal anxiety and infant feeding outcomes. For this reason, we investigated the associations of postnatal anxiety and a range of factors including IR and IU.
Method:
Postnatal women (n=126), predominantly white Irish, completed an anonymous online survey assessing postnatal anxiety, IU and IR, and infant feeding. Hierarchical multiple regression analyses were tested for unique predictors of postnatal anxiety. Multivariate tests were used to assess variables associated with feeding outcomes.
Results:
Although both IR and IU were significantly correlated with postnatal anxiety, regression analyses found only IR accounted for a significant amount of unique variance in postnatal anxiety. In terms of feeding outcomes, IR and IU were associated with reduced likelihood to breastfeed.
Conclusions:
IU and IR may have different impacts on postnatal anxiety. IU and IR may explain the higher incidence of anxiety in postnatal women and impact on a mother’s decision to breastfeed her infant. Although important, these are results of a small cross-sectional study with some limitations. As such, they should be interpreted with caution. More investigation of these concepts would be beneficial.
This commentary suggests that the meaning and content of dignity is bound to the broader question of who is said to have personhood and sovereignty, and thus protection and rights under the law, and who is excluded from our legal community.
Twenty-five years ago, the dripzone hypothesis, whereby the proximity of understorey conifer branches to the crown of dominant Populus trees significantly increased the diversity and abundance of cyanolichens on these conifers, was first described from western North America. Here, we report a similar phenomenon from eastern North America on conifers under the dripzone of yellow birch and aspen trees. We present field observations of this pattern as well as a quantitative analysis of three humid boreal forests from the Island of Newfoundland. For the latter, we examined epiphytic lichen composition on branches of balsam fir within and immediately outside the dripzone of yellow birch trees. The dripzone effect was strong and spatially restricted to the area under the canopy of yellow birch, as well as aspens, on wet sites in humid forests, with significantly more cyanolichens on balsam fir branches under the yellow birch and aspen canopies. Genera of cyanolichens predominantly found under the dripzone included Fuscopannaria, Leptogium, Lobaria, Lobarina, Neproma, Pannaria, Parmeliella, Pectenia, Pseudocyphellaria and Ricasolia, and included the COSEWIC listed Pectenia plumbea. We suggest here that the canopy of broadleaf phorophytes not only shape the cyanolichen community on understorey conifers by chemical enrichment of the throughfall, but also probably from enrichment by cyanolichens within their own canopy, which also contribute abundant cyanolichen propagules.
This article focuses on the use of the terms “deaf” and “deaf-mute” in the interwar Romanian press to explore the multiplicity of meanings attached to this condition in different types of public discourse. My aim is to place in the larger context of that period what meanings become most prominent in newspapers and other forms of popular press, why, and with what consequences. I offer an exploration of these discourses to better appreciate how the reading public, both able-bodied and disabled, saw disability represented. Rendering the very multiplicity of meanings attached to “deafness” visible in the relevant context is an important goal for this essay; it allows us to better understand the continued imprecision and stigmatizing framework in how Romanian society engaged with the deaf. I also explore what space existed for the deaf community to shape their own self-representations. Placing ableist discourses in dialogue with the voices of the deaf community is an important aim, as a method to de-essentialize the predominant ableist discourses and normalize accounting for disability as a significant element of modern history.
This article examines the Russian Fund for Invalids of the War in Afghanistan (RFIVA), a post-Soviet disability organization whose disabled veteran members became involved in organized crime after the collapse of the Soviet Union, ultimately culminating in the 1996 Kotliakovskoe Cemetery bombing. When the Soviet state vanished, disabled people felt the effects of its absence most harshly. But disabled veterans of the Soviet-Afghan War, who had constructed a shared identity around violent disabled masculinity, found both solidarity and profit in the sale of violence in the hyper-capitalist, neoliberal Russia. During Russia’s transition to a market economy, a small part of the Afghan veteran’s movement formed into criminal and semi-criminal organizations, including the Russian Fund for Invalids of the Afghan War (RFIVA). The organization eventually splintered over disagreements regarding its obligations to provide care for disabled veterans: a reflection of broader questions over the relationship of disabled veterans to Russian society.
The high cost of medication is a common challenge for many Americans. This is particularly true for patients served by Federally Qualified Health Centers (FQHCs) that often have low income and are medically vulnerable. In this article I discuss the history and purpose behind the creation of the 340B drug pricing program, legislation enacted to limit the cost of drugs used by patients covered by Medicaid that requires drug manufacturers to enter into discount agreements with the Health Resources and Services Administration (HRSA), and how for years this program has been used to finance health care provision for communities that use FQHCs as their source of primary care. Additionally, I will discuss the history behind the creation of FQHCs and how that mission is affected by litigation and proposed reforms that would limit the ability of FQHCs to leverage savings and revenue from the program to fund health services for their patient populations. I argue that reinforcement of existing discounting practices, along with limited reforms of the 340B program are necessary to avoid disruption of health care provision for patients of FQHCs and to ensure that the 340B program continues to perform as intended.