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To improve transitions in care, a new patient navigation (PN) program was introduced to support older adults with complex care needs transition from hospital to home. The patient navigator is a community social worker embedded in the hospital’s care teams. A cohort observational design was used to conduct the study by analysing the patient navigator’s clinical notes and hospital’s administrative data to describe the characteristics of patients, scope of the patient navigator’s activities, and patient outcomes. Ninety patients were assigned to the patient navigator’s caseload (November 2019–November 2021) in which the average age was 78.9 (range 55–95). The most frequent PN intervention types were referrals to community services (66%, n = 59) and discharge planning (61%, n = 55). The patient navigator supported 66% patients (n = 59) in returning home and provided follow-up care for 74 days (average). This study provides important insights into the patient navigator’s role to guide decision makers in implementing PN programs for older adults in a hospital setting.
The development of multilevel regression and poststratification (MRP) has allowed scholars to more accurately estimate subnational public opinion using national polls. However, MRP generally recovers less accurate estimates from polls whose respondents are selected using cluster sampling – also called area-probability sampling. This is in part because cluster-sampled polls rely on a complex form of random sampling focused on national representativeness that may result in small or unrepresentative subsamples in subnational geographies. This has limited MRP’s usefulness in subnational opinion estimation in several contexts, including historical polls in the US, where cluster-sampling was common into the 1980s, and large academic studies in many countries today. In this paper, I propose two approaches to improve estimation from MRP with cluster-sampled polls. The first is pooling data from multiple surveys to produce a larger sample of clusters. The second is clustered MRP (CMRP), which extends MRP by modeling opinion using the geographic information included in a survey’s cluster-sampling procedure. Using simulations, I show that both methods improve upon traditional MRP, and I validate them using historical polls in the US
Spinal CSF leak can cause disabling headaches and neurological symptoms. Lack of awareness, diagnostic delay and treatment inconsistencies affect the quality of CSF leak care globally. This is the first study aiming to identify and assess these challenges in Canada.
Methods:
A cross-sectional online survey of Canadian patients with spinal CSF leak was designed in collaboration with Spinal CSF Leak Canada, including questions on demographics, headache condition, investigations, treatments, quality of life, financial consequences and out-of-country care.
Results:
The survey captured 103 respondents with confirmed spinal CSF leak diagnosis, of whom 56% were still suffering. The majority were female (80%), most being highly educated, with a mean age of 41.8 (SD: 10.37) years at the time of diagnosis. Inconsistencies in care resulted in variable durations for obtaining diagnosis and treatment. The majority of respondents (88%) had seen multiple physicians, and only 50% had seen a CSF leak specialist. Invasive imaging was not performed in 43%. CSF leak relapse after initial successful treatment occurred frequently (43%). The incidence of rebound intracranial hypertension was high (52.5%), and the treatment was difficult to access (77%). Out-of-country care was common (28%), and the impact on financial health was omnipresent (81.5%).
Conclusion:
The survey demonstrates significant gaps in spinal CSF leak care in Canada, similar to global observations. Lack of awareness and access, delayed care, and inconsistencies in investigations and management are common. Spinal CSF leak significantly impacts patients’ physical, mental and financial well-being. Increased awareness, referral pathways and standardized treatment algorithms are key factors in optimizing patient care in Canada.
Let $f,g$ be $C^2$ expanding maps on the circle which are topologically conjugate. We assume that the derivatives of f and g at corresponding periodic points coincide for some large period N. We show that f and g are ‘approximately smoothly conjugate.’ Namely, we construct a $C^2$ conjugacy $h_N$ such that $h_N$ is exponentially close to h in the $C^0$ topology, and $f_N:=h_N^{-1}gh_N$ is exponentially close to f in the $C^1$ topology. Our main tool is a uniform effective version of Bowen’s equidistribution of weighted periodic orbits to the equilibrium state.
Unlike in solids, heat transfer in fluids can be greatly enhanced due to the presence of convection. Under gravity, an unevenly distributed temperature field results in differences in buoyancy, driving fluid motion that is seen in Rayleigh–Bénard convection (RBC). In RBC, the overall heat flux is found to have a power-law dependence on the imposed temperature difference, with enhanced heat transfer much beyond thermal conduction. In a bounded domain of fluid such as a cube, how RBC responds to thermal perturbations from the vertical sidewall is not clear. Will sidewall heating or cooling modify flow circulation and heat transfer? We address these questions experimentally by adding heat to one side of the RBC. Through careful flow, temperature and heat flux measurements, the effects of adding side heating to RBC are examined and analysed, where a further enhancement of flow circulation and heat transfer is observed. Our results also point to a direct and simple control of the classical RBC system, allowing further manipulation and control of thermal convection through sidewall conditions.
To characterize fluid flow in the slip regime, the use of Navier–Stokes–Fourier (NSF) equations with slip boundary conditions is prevalent. This trend underscores the necessity of developing reliable and accurate slip boundary conditions. According to kinetic theory, slip behaviours are intrinsically linked to the gas scattering processes at the surface. The widely used Maxwell scattering model, which employs a single accommodation coefficient to describe gas scattering processes, reveals its limitations when the difference between accommodation coefficients in the tangential and normal directions becomes significant. In this work, we provide a derivation of velocity slip and temperature jump boundary conditions based on the Cercignani–Lampis–Lord scattering model, which applies two independent accommodation coefficients to describe the gas scattering process. A Knudsen layer correction term is introduced to account for the impact of the surface on the velocity distribution function, which is associated with the scattering model. The governing equation of the correction term is established based on the linearized Boltzmann equation. Additionally, two moments are derived to capture the collision effect in the Knudsen layer: a conserving moment of collision invariants, and an approximate higher-order conserving moment. These moments are then employed to determine the coefficients in the correction term. We demonstrate that the derived slip coefficients align closely with numerical results obtained by solving the Boltzmann equation in the Knudsen layer. Besides, we apply the derived slip boundary conditions within the framework of the NSF equations, yielding numerical results that exhibit excellent consistency with those obtained through molecular-level simulations.
Early mild traumatic brain injury (mTBI or concussion sustained between 0 and 5 years old) can lead to post-concussive symptoms, behavioral changes, and cognitive difficulties. Although school-age children (6–17 years old) experience similar consequences, severe neuropsychological deficits are not common, and the majority have no persisting symptoms after one month. Thus, there may be value in focusing on what characterizes optimal functioning (or wellness) after mTBI, but this has not been explored in young children. This study documents the evolution and predictors of optimal functioning after early mTBI.
Method:
Participants were 190 children aged 18 – 60 months with mTBI (n = 69), orthopedic injury (OI; n = 50), or typical development (TDC; n = 71). Optimal functioning was defined as: (1) no clinically significant behavioral problems; (2) no cognitive difficulties; (3) no persisting post-concussive symptoms; (4) average quality of life or better. Predictors related to sociodemographic, injury, child, and caregiver characteristics included number of acute symptoms, child sex, age, temperament, maternal education, parent-child attachment and interaction quality, and parenting stress.
Results:
Fewer children with mTBI had optimal functioning over 6 and 18-months post-injury compared to those with OI and TDC. Higher parent-child interaction quality and lower child negative affectivity temperament independently predicted optimal functioning.
Conclusion:
Children who sustain early mTBI are less likely to exhibit optimal functioning than their peers in the long-term. Parent-child interaction quality could be a potential intervention target for promoting optimal function.
The effects of reshock conditions, including the interface evolution state before reshock and the second shock intensity, on interface instability induced by two successive shocks propagating in the same direction are investigated via shock-tube experiments. It is observed that the reshock promotes the interface instability, and the post-reshock perturbation evolution relates to both the pre-reshock interface evolution state and second shock intensity. For the linear evolution of the twice-shocked interface, existing models perform poorly when either the pre-reshock interface shape effect or the secondary compression effect is pronounced, as current reduction factors fail to accurately describe these effects. Besides, the reshock-induced linear amplitude growth rate shows a non-monotonic dependence on the scaled pre-reshock amplitude, primarily due to the shape effect of the pre-reshock interface. For the post-reshock nonlinear evolution, the model proposed by Zhang & Guo (J. Fluid Mech., vol. 786, 2016, pp. 47–61) offers reasonable predictions when the second shock is weak. However, when the second shock is moderately strong, the model overestimates the bubble growth and underestimates the spike evolution under the influence of the significant secondary compression effect. Furthermore, empirical linear and nonlinear models capable of describing the dependence of the post-reshock evolution on reshock conditions are proposed based on the present experimental results and existing models.
The objective was to evaluate the performance of suckling piglets based on their choice of mammary gland. A completely randomized design was used, considering the position of the mammary glands pair and their respective piglets as experimental unit. The mammary gland position was considered for the treatments, being 1st, 4th and 7th pair. The ration and leftovers were weighed daily to obtain daily feed intake of the sow. On post-natal day (PND) 3 and 21, 80 ml of milk was collected to analyse crude protein, fat, lactose, non-fatty solids, mineral matter and total solids. On PND 3 and 21, the piglets were weighed to determine weight gain and estimate milk consumption. The piglets' longitudinal length and head circumference were measured in the same period and estimated body surface area/mass ratio. Blood samples from the sows and piglets were collected on PND 3 and 21 to analyse total cholesterol, triglycerides, total protein, fractions and glucose. There was an effect of mammary gland position on piglets at PND 21 suckling on the 7th pair, which had a 23.88 cm2/kg greater body surface/mass ratio compared to those who suckled in the 1st pair. In turn, at PND 21, the piglets that suckled in the 1st pair presented higher weight, weight gain and milk consumption (0.685, 0.033 and 0.127 kg, respectively) than those that suckled in the 7th pair. Anterior mammary glands result in better productive performance and better chances of maintaining piglet homeostasis at PND 21.
This article presents a novel sense in which theoretical structure has been preserved across the transition from classical to quantum physics. I import mathematical tools from category theory that have been used for structural comparisons in the context of theoretical equivalence and apply these tools to new situations involving theory change. The structural preservation takes the form of a categorical equivalence between categories of models of classical and quantum physics. I situate the significance of this structural preservation in terms of prospects for theory construction in quantum physics.
This study highlights key players for COVID-19 in Brazil, Peru, Colombia, Chile, Argentina, and Ecuador by employing social network analysis for Twitter. This study finds that key players in Latin America play various roles in COVID-19 social networks, differing from country to country. For example, Brazil has no Latin key players, whereas Colombia and Ecuador have 8 Latin key players in the top 10 key players. Secondly, the role of governmental key players also varies across different countries. For instance, Peru, Chile, Argentina, and Ecuador have the governmental key player as the top key player, whereas Brazil and Colombia have the news media key player as the first. Thirdly, each country shows different social networks according to groups. For instance, Colombia exhibits the most open social networks among groups, whereas Brazil shows the most closed social networks among the 6 Latin countries. Fourthly, several top tweeters are common across the 6 Latin American countries. For example, Peru and Colombia have caraotadigital (Venezuelan news media), and Chile and Argentina have extravzla (Venezuelan news media) as the top tweeter.
A new dalmanitid trilobite is described from the early Silurian (Telychian) Waukesha Biota in Wisconsin, USA, best known for its variety of exceptionally preserved arthropods. Waukeshaaspis eatonae new genus new species is the most common trilobite found in the Waukesha Biota, numbering ~200 specimens, allowing a thorough description of the dorsal exoskeleton. This new taxon has a combination of characters unique to the Dalmanitidae, including a distinct embayment on the posterior margin of the pygidium. Embayments are rare for dalmanitids, most species having instead a caudal spine. The lengthening of the genal spines might have served a similar function to that which a caudal spine would have served, allowing the embayment to fulfill a different function, related to keeping an opening when enrolled. The abundance at the preservation site suggests physiological tolerance at the habitation site.
This essay analyses the Holy See's engagement in the postwar discourse surrounding displaced minors by focusing on the case of displaced Italian children from Libya. Separated from their families and evacuated to Italy at the onset of the Second World War, they were placed in Italian Youth of the Lictor (Gioventù Italiana del Littorio; GIL) camps. In the aftermath of the war, these displaced children petitioned to return to their families who had remained in territories no longer part of the Italian empire. This article shows how the Papal Aid Committee for Assisting Refugees took part in the relocation efforts and contributed to the conversation on family reunification. By navigating postwar aid and forming unexpected alliances, the Holy See not only contributed to reshaping Italy's geopolitical presence in the Mediterranean but also solidified conservative family norms within the international discussion on humanitarianism.
Duchenne muscular dystrophy is characterised by fibrofatty replacement of muscle, resulting in dilated cardiomyopathy. Hypertrophic cardiomyopathy affects 1:200–1:500 people and is characterised by asymmetric ventricular septal hypertrophy. To date, there have been two separately reported cases describing the combined pathology of these disorders. Herein, we expand upon these reports with a case series describing longitudinal findings in three patients with Duchenne muscular dystrophy who developed hypertrophic cardiomyopathy.
In this study, we approximately replicated Papi and Khajavy’s (2021) investigation into the regulatory focus in second language acquisition, applying their approach to a significantly larger cohort of 855 Chinese second language (L2) learners. In contrast with the original study, our research employed the College English Test Band 4 (CET-4), a standardized English test, to better align with the Chinese educational context. This methodological shift allowed for a nuanced exploration of the regulatory focus’s role in language learning among Chinese students. Our results predominantly reinforce the crucial role of regulatory focus in language learning, echoing Papi and Khajavy’s findings. We discovered notable parallels in how promotion positively influences ideal own and ideal other, and how prevention negatively impacts ought own and ought other. However, a unique finding of our study was the stronger impact of ought selves on L2 anxiety and enjoyment in the Chinese context. This highlights the nuanced influence of socioeducational environments on regulatory focus strategies, suggesting contextual variability in language learning strategies.
The liver has multiple functions such as detoxification, metabolism, synthesis and storage. Folate is a water-soluble vitamin B9, which participates in one-carbon transfer reactions, maintains methylation capacity and improves oxidative stress. Folic acid is a synthetic form commonly used as a dietary supplement. The liver is the main organ for storing and metabolising folate/folic acid, and the role of folate/folic acid in liver diseases has been widely studied. Deficiency of folate results in methylation capacity dysfunction and can induce liver disorders. However, adverse effects of excessive use of folic acid on the liver have also been reported. This review aims to explore the mechanism of folate/folic acid in different liver diseases, promote further research on folate/folic acid and contribute to its rational clinical application.