To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
We perform numerical simulations of two-dimensional strongly stratified flows in a square periodic domain $(y,z)$ forced by a steady mode with vorticity of the form $\sin (k_{\textit{y f}}y)\sin (k_{\textit{z f}}z)$, where $(k_{\textit{y f}},k_{\textit{z f}})$ are fixed wavenumbers. It is shown that such deterministic forcing can lead to a transition to turbulence and the emergence of horizontal layers (so-called vertically sheared horizontal flows, VSHFs) similarly as for random stochastic forcing. The flow characteristics are studied depending on the Froude and Reynolds numbers. Furthermore, the mechanisms of layers formation are disentangled. Triadic instabilities first lead to the growth of pairs of wavevectors that resonate with each of the four forced wavevectors. Quadratic interactions between these resonant modes and the forcing also drive the growth of several non-resonant modes at the same growth rate. Since the forcing comprises the wavevectors $\pm (k_{\textit{y f}},k_{\textit{z f}})$ and their mirror symmetric with respect to the horizontal $\pm (k_{\textit{y f}},-k_{\textit{z f}})$, there exist enslaved/bound modes with the same horizontal wavenumber and different vertical wavenumbers. Hence, the quadratic interactions between the latter modes force a second generation of modes among which some are VSHFs. Their growth rate is twice the growth rate of the primary resonant modes. Such a mechanism is similar to resonant quartets (Newell, J. Fluid Mech., 1969, vol. 35, no 2, pp. 255–271; Smith & Waleffe, Phys. Fluids, 1999, vol. 11, no 6, pp. 1608–1622). When the forcing is restricted to only the two wavevectors $\pm (k_{\textit{y f}},k_{\textit{z f}})$, the second generation of enslaved/bound modes all have a non-zero horizontal wavenumber. However, further quadratic interactions can force VSHF. Thus, horizontal layers also emerge, but with a growth rate equal to the number of quadratic interactions times the growth rate of the primary instability.
This paper responds to Rosolini’s suggestion to use the ultracompletion of a category as a way to understand versions of conceptual completeness. Over 50 years ago, Kock and Mikkelsen observed in effect that one obtains ultracompletions of the category of sets by factorising ultrapower functors. They gave a concrete description of the factorisation under what they recognised were special conditions. In parallel work, Volger obtained a different description using categorical logic. Here, I revisit these ideas using Tripos Theory and show in particular that any left exact functor of toposes admits a Kock–Mikkelsen factorisation. In this reading, the ultracompletion appears amongst the various regular and exact completions which have been studied in particular by members of the Italian Category Theory School.
Community-acquired pneumonia (CAP) is a leading cause of hospitalization and mortality in the US. Studies report racial disparities in various infectious syndromes. Our objective was to assess the relationship between patient race and antibiotic prescribing in inpatient CAP management.
Design:
Retrospective cohort study.
Setting:
11 Cleveland Clinic community hospitals.
Patients:
Patients aged ≥18 years hospitalized with CAP between November 1, 2022, and January 31, 2025.
Methods:
Parametric and non-parametric methods were used to describe demographic and clinical differences by race. The association between race and extended spectrum antibiotic (ESA) guideline concordance was assessed using multivariable logistic regression models adjusting for age, gender, admission source, area deprivation index (ADI), hospital, diabetes, cardiovascular disease, chronic respiratory disease, renal failure, liver disease, immunocompromising condition, alcohol and substance use disorder, dialysis, and clinical instability and severity on day 1.
Results:
In bivariate analyses, Non-Hispanic Black (NHB) patients were less likely than NHW patients to receive ESA guideline-concordant CAP therapy (63.2% vs 64.4%; OR = 0.91, P = .2). After adjusting for patient characteristics, there were no differences between NHB and NHW patients in receipt of ESA therapy (adjusted OR = 0.93; 95% CI = 0.83, 1.00). After adjusting for hospital, NHB patients were more likely to receive ESA guideline-concordant CAP therapy (adjusted OR = 1.17; 95% CI = 1.06, 1.30).
Conclusion:
NHB patients were more likely to receive ESA-guideline concordant therapy, but this was influenced by where they sought care. Further studies are needed to understand why prescribing varies across hospitals.
Research on the special engineering properties of laterite has highlighted the importance of interactions between colloidal oxides and clay minerals, yet their exact microscopic mechanisms remain elusive. To address this, this study employs molecular dynamics simulations to investigate the impact of isomorphic substitution on the interactions between illite and colloidal alumina. The stable configurations and the potential of mean force for these interactions were determined. The simulation results reveal that the heterogeneous charge distribution across the surfaces of illite and colloidal alumina underpins their interaction. Specifically, the negatively charged {001} surface of illite forms a stable adsorption structure with the positively charged Al atoms of colloidal alumina. Meanwhile, equilibrium cations (K+) and atoms from isomorphic substitution induce electrostatic attractions with O and Al atoms in colloidal alumina, leading to two localized stable states and an intermediate transition state on the {00-1} surface of illite. Furthermore, Mg substitution in the octahedral sheet and Al substitution in the tetrahedral sheet reduce the layer charge density, thereby weakening the affinity of the illite {00-1} surface for colloidal alumina. Conversely, Fe substitution in the octahedral sheet increases the local charge density, enhancing the attraction of the {001} surface. These simulation results provide molecular-level insights into the mechanisms governing the behaviour of laterite, offering a theoretical foundation for guiding future experimental studies and for the engineering application and performance control of laterite soils.
We present a back-in-time analysis for the origin of vorticity in viscous separated flows over immersed bodies, using the adjoint-vorticity framework recently introduced by Xiang et al. (2025 J. Fluid Mech. vol. 1011, A33. The solution of the adjoint-vorticity equations yields the volume density of mean deformation, which captures the stretching and tilting of the earlier vorticity that leads to the terminal value. The analysis also takes into account the boundary contributions of vorticity and its flux. Three examples are considered. Steady, axisymmetric separation in the flow over a sphere at Reynolds number $Re=200$ is shown to be established due to wall flux from both upstream and downstream of separation, the latter contribution being absent from the classical description by Lighthill. For unsteady separation at higher $Re=300$, the streamwise vorticity within the wake hairpin vortex is traced back, quantitatively, to the azimuthal vorticity on the sphere. The third configuration is the flow over a prolate spheroid at $Re=3000$. The null vorticity at three-dimensional separation originates from the cancellation of opposite interior contributions adjacent to the separation surface. The contribution from the downstream side migrates across the separation surface into the upstream region due to a tilting effect – a fundamental distinction between two- and three-dimensional separation. We also examine the detached vortical structures. The streamwise vorticity in the primary vortex originates from tilting of near-wall azimuthal vorticity, differing from Lighthill’s conjecture that the origin is streamwise near-wall vorticity that arises due to the reduced Coriolis force. Finally, a necklace vortex in the turbulent wake is traced back in time, and is shown to have contributions from the spheroid trailing-edge shed shear layer and the large-scale counter-rotating primary vortices.
Cancer-related fatigue is a common problem among colorectal cancer (CRC) survivors even after completion of treatment. In a randomised trial, we assessed the effect of a person-centred lifestyle programme on cancer-related fatigue among CRC survivors who completed treatment. Survivors who completed treatment at least 6 months but no longer than 5 years ago and who were experiencing cancer-related fatigue were randomised to intervention or control group. The intervention group worked with a lifestyle coach for 6 months during twelve sessions to stepwise increase adherence to the World Cancer Research Fund/American Institute of Cancer Research cancer prevention guidelines on healthy diet and physical activity. The control group did not receive lifestyle coaching. Changes in cancer-related fatigue from baseline to 6 months were assessed with the FACIT (Functional Assessment of Chronic Illness Therapy) – Fatigue Scale. As a secondary outcome, we assessed changes in health-related quality of life (HRQoL). Higher scores indicate less fatigue and better HRQoL. Eighty participants were randomised to the intervention group; eighty-one to the control group. Baseline characteristics were similar: mean age 64·1 (sd 10·9) years; 55·3 % were women; and 72 % had colon cancer. There were favourable changes in dietary behaviours and physical activity in the intervention group; the control group did not show changes to the same extent. The programme did not result in statistically significant differential changes over time between intervention and control group in cancer-related fatigue (0·8; 95 % CI −1·6, 3·2) or HRQoL (1·3; 95 % CI −2·2, 4·8). A person-centred lifestyle programme improved the lifestyle of CRC survivors, but the programme was not effective in reducing cancer-related fatigue or in improving HRQoL.
Shock trains compress incoming supersonic flow through a series of shock wave/turbulent boundary layer interactions (STBLIs) that occur in rapid streamwise succession. In this work, the global flow changes across the entire turbulent shock train are analysed as the confluence of local changes imparted by individual STBLIs. For this purpose, wall-resolved large eddy simulations are used on a constant area, back-pressured channel configuration with an entry Mach number of 2.0. Local changes due to individual STBLIs are evaluated in terms of deviations from incoming, near-equilibrium boundary layers, by systematically examining properties of the mean flow structure and turbulent statistics. The first STBLI in the train induces a strongly separated region, which interrupts inner layer dynamics and incites wall-normal deflection of turbulent structures, leading to prominent outer layer Reynolds stress amplification and related transport phenomena. Downstream of the first STBLI, the thickened, turbulent wall layer repeatedly interacts with subsequent shock waves in the train, resulting in cyclic attenuation and amplification of turbulent stresses, localised incipient separations and variations in mean momentum flux gradients. Decreases in mean Mach number along the shock train result in downstream shocks weakening to the point that interactions with the turbulent boundary layer impart negligible changes on the local flow. Consequently, after a sufficient streamwise extent, the boundary layers asymptote towards a new equilibrium state, thus recovering certain classical properties of near-wall turbulence. Among the features that reappear are a self-similar, adverse pressure gradient velocity profile and the restoration of the autonomous roller-streak cycle.
General additive functionals of patricia tries are studied asymptotically in a probabilistic model with independent, identically distributed letters from a finite alphabet. Asymptotic normality is shown after normalization together with asymptotic expansions of the moments. There are two regimes depending on the algebraic structure of the letter probabilities, with and without oscillations in the expansion of moments. As applications firstly the proportion of fringe trees of patricia tries with k keys is studied, which is oscillating around $(1-\rho(k))/(2H)k(k-1)$, where H denotes the source entropy and $\rho(k)$ is exponentially decreasing. The oscillations are identified explicitly. Secondly, the independence number of patricia tries and of tries is considered. The general results for additive functions also apply, where a leading constant is numerically approximated. The results extend work of Janson on tries by relating additive functionals on patricia tries to additive functionals on tries.
Predatory mites are important biological control agents of spider mites in various crops. Long-term mass rearing on alternative foods, such as plant pollen, may affect their predatory efficiency, but data on Euseius scutalis are scarce. Therefore, this study aimed to evaluate whether long-term rearing of E. scutalis on cattail pollen influences its functional response when fed on Tetranychus turkestani. Functional and numerical responses of the predatory mite E. scutalis reared on cattail (Typha latifolia) pollen over 30 generations on different densities (2, 4, 8, 16, 32, 64, and 128) of T. turkestani were evaluated. The results indicated a type II functional response for E. scutalis on T. turkestani in all generations (G1, G10, G20, and G30) tested. The attack rate (a) of E. scutalis increased as the number of generations increased. The handling time decreased as the number of generations increased from G1 (0.330 h) to G10 (0.318 h), then increased in G20 (0.572 h) and then decreased again in G30 (0.385 h). In G1 and G30, the number of eggs deposited by the predator increased as prey density increased. However, in G10 and G20, egg deposition increased up to 64 prey and then slightly decreased at 128 prey. The results indicated that the quality of E. scutalis did not lessen against T. turkestani after different periods of rearing on cattail pollen. Based on this study, we recommend cattail pollen as a good candidate for the large-scale rearing of E. scutalis for use in biological control programmes against T. turkestani.
Rather than considering popular culture in the service of states, this article directs attention instead to the social level and how fan clubs pursue their own non-state international relations. Through a comparative study of Tottenham Hotspur Supporters’ Clubs and the BTS ARMY, the article offers a tripartite framework for analysis of the previously neglected international relations of fan clubs, unpacking their distinctive transnational practices, identities, and activism. The discussion considers how fan clubs have developed their own parallels to interstate politics in their transnational practices, and advanced alternative identities rejecting state-centric territorial demarcations. In contrast to accounts of the reproduction in popular culture of elite narratives, the article highlights how fan clubs may serve to reframe and reorient from below representations of even the most exclusive aspects of interstate relations including their instruments of violence. With reference to the common case study of the Black Lives Matter movement, the article also unpacks distinctive dynamics of transnational activism among fan clubs, elaborating how techniques originally mobilized in relation to the fandom object have been transferred to address global political issues. The limitations to each of these aspects are subsequently considered in view of fan clubs’ embedding in contemporary capitalist and geopolitical relations.
In this article, I address the political, social, and humanitarian issues at the core of my works for the stage. Through examples from my operas El Palacio Imaginado (2003), La tierra de la miel (2012), and Harriet (2018), I discuss how gender issues, social justice, and the burden of racism have transformed my musical language. La tierra de la miel dramatizes the tragedy of human trafficking on the US/Mexico border through the fictionalized story of two of its victims, driven into prostitution and physically and sexually abused. The opera seeks to give a voice to the hundreds of Mexican women (often from Indigenous communities) murdered along the border between the US and Mexico. Harriet recounts episodes from the life of abolitionist Harriet Tubman, including her concerted actions to end the institution of slavery, and ends with a message expressing hope for a continuation of her fight against slavery and racism.
This article describes a novel series of classroom simulations for teaching Graham Allison’s (1971) three seminal models of foreign policy decision making (i.e., the Rational Actor Model, the Organizational Process Model, and the Bureaucratic Politics Model) and demonstrates the effectiveness of those simulations. The simulations utilize the commercially available board game, 13 Days: The Cuban Missile Crisis, 1962. The game is a close approximation of the Rational Actor Model. The author developed two additional rule variants to represent the Organizational Process Model and the Bureaucratic Politics Model. The effectiveness of the simulations was evaluated with both a survey and a quiz administered to a treatment section that experienced the simulations and a control section that did not. The results indicate that the simulations are effective pedagogical tools associated with higher student excitement and enjoyment of the material, higher quiz scores, and an increased ability to self-assess understanding of the material.
The macrofossil record of the lower Palaeozoic Stavelot-Venn Inlier is revised. This inlier is the largest of the four inliers of the Ardenne Allochthon in southern Belgium and northern France, and it extends from southeastern Belgium into western Germany. The thick succession of mostly siliciclastic rocks has been traditionally assigned to the lower Cambrian to Middle Ordovician, but macrofossils are extremely rare and the microfossil (acritarch) records need revision. The presence of the ichnogenus Oldhamia indicates an early/middle Cambrian age for the lower (but not lowest) part of the succession. The graptolites from the Rhabdinopora fauna clearly point out the presence of the Tremadocian (Lower Ordovician) strata; they are locally associated with small linguliformean brachiopods (e.g., Broeggeria, Lingulella). The present revision, based on examination of the Belgian material, indicates that none of the trilobite, phyllocarid and sponge records in the literature can be confirmed. From all macrofossils mentioned in the literature, only few linguliformean brachiopod levels can be confirmed in the (? middle–upper) Cambrian and in the Lower Ordovician. The alleged bivalve from the Cambrian of the French part of the Rocroi Inlier is reillustrated.
This article defends a new type of preferential hiring. Rather than compensating groups for past or present employment-related discrimination, it seeks to ensure that groups with disproportionate unemployment rates that are due significantly – but not necessarily wholly – to their members having relatively narrow competencies, such as autistic individuals and people with hearing loss, ADHD and lower education levels, are prioritized for jobs that match their abilities. After defending such competency-based preferential hiring based on its benefits for persons with narrower competencies and for societies more broadly, I address several criticisms, including concerns that this approach may be stigmatizing.
This study investigates the reading of novel morpho-syntactic forms, specifically gender-inclusive writing in French. Inclusive writing aims to address the generic use of the masculine form, which often encourages male mental representations over female or non-binary ones. The study focuses on contracted forms using the mid-dot, such as étudiant·e·s, which have become widespread in French despite ongoing public debate. Four experiments using eye-tracking and self-paced reading methods compared reading times for inclusive, masculine, and feminine forms. Experiment 1 found no robust difference in reading times between inclusive forms ending in “·e” and their feminine counterparts, suggesting familiarity with this form. Experiment 2 showed that inclusive forms ending in “·ne”, such as comédien·ne·s, were read more slowly than their feminine counterparts, possibly due to phonological effects. Experiment 3 tested highly pronounceable inclusive forms like auteur·rice·s, which were read more slowly initially, but this effect was short-lasting. Experiment 4 compared more or less pronounceable forms, such as chanteur·euse·s and chanteur·se·s, respectively, confirming that the degree of pronounceability affects reading times. Overall, the study concluded that the reading time for contracted inclusive forms depends on familiarity and the degree of pronounceability.
We show that for any integer $k\ge 1$ there exists an integer $t_0(k)$ such that, for integers $t, k_1, \ldots , k_{t+1}, n$ with $t\gt t_0(k)$, $\max \{k_1, \ldots , k_{t+1}\}\le k$, and $n \gt 2k(t+1)$, the following holds: If $F_i$ is a $k_i$-uniform hypergraph with vertex set $[n]$ and more than $ \binom{n}{k_i}-\binom{n-t}{k_i} - \binom{n-t-k}{k_i-1} + 1$ edges for all $i \in [t+1]$, then either $\{F_1,\ldots , F_{t+1}\}$ admits a rainbow matching of size $t+1$ or there exists $W\in \binom{[n]}{t}$ such that $W$ intersects $F_i$ for all $i\in [t+1]$. This may be viewed as a rainbow non-uniform extension of the classical Hilton-Milner theorem. We also show that the same holds for every $t$ and $n \gt 2k^3t$, generalizing a recent stability result of Frankl and Kupavskii on matchings to rainbow matchings.
Surface bubbles in the ocean are critical in moderating several fluxes between the atmosphere and the ocean. In this paper, we experimentally investigate the drainage and lifetime of surface bubbles in solutions containing surfactants and salts, subjected to turbulence in the air surrounding them modelling the wind above the ocean. We carefully construct a set-up allowing us to repeatably measure the mean lifetime of a series of surface bubbles, while varying the solution and the wind speed or humidity of the air. To that end, we show that renewing the surface layer is critical to avoid a change of the physical properties of the interface. We show that the drainage of the bubbles is well modelled by taking into account the outwards viscous flow and convective evaporation. The mean lifetime of surface bubbles in solutions containing no salt is controlled by evaporation and independent on surfactant concentration. When salt is added, the same scaling is valid only at high surfactant concentrations. At low concentrations, the lifetime is always smaller and independent of wind speed, owing to the presence of impurities triggering a thick bursting event. When the mean lifetime is controlled by evaporation, the probability density of the lifetime is very narrow around its mean, while when impurities are present, a broad distribution is observed.
The limbic system is a brain structure involved in emotional regulation. Since nutritional interventions in very low birth weight (VLBW) infants may be associated with measurable differences in brain structure and function, we designed this prospective study to evaluate the impact of early nutritional support in VLBW infants on the volume of the regions that comprise the limbic system, as well as on the emotional and neuropsychological development of these infants. This is a prospective observational study of a historical cohort of children with a history of prematurity. Seventy-four preterm infants, with a mean age of 11·1 (sd 2·9) years, underwent neuropsychological assessment using the Wechsler Intelligence Scale for Children and functional MRI (fMRI). We recorded the nutritional intake during the first week of the neonatal period, as well as data related to neonatal morbidity. The association between the results of the brain structural analysis, psychometrics variables and nutritional intake was determined using simple and multivariate linear regression adjusted for child age and BMI in the structural analysis of fMRI. Lipids intake was also associated with the volume of the left thalamus (b = 50·7; P = 0·014), the right thalamus (b = 47·4; P = 0·018) and the left nucleus accumbens (b = 5·02; P = 0·031). We conclude that lipids intake in the first week of life in VLBW newborns is associated with the volume of various structures of the limbic system, namely the thalamus and the nucleus accumbens.