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Reducing stigma and discrimination has been a priority in many national mental health policies for decades. Focusing efforts requires us to understand where this has the greatest impact on people with mental health problems. In 2024, we conducted a nationally representative survey that aimed to assess the burden of discrimination (as a product of frequency and impacts of experiences). Secondary aims were to quantify the types of discrimination experienced in different life domains and the sociodemographic and mental health problem characteristics of those experiencing higher burden.
Methods
Online surveys were completed by 6032 members of the general Australian community aged 18 years and over. The survey was carried out by the survey company The Social Research Centre, using their Life in Australia™ probability-based panel. Those who reported a mental health problem or scored high on the Kessler 6 measure of psychological distress (n = 2613) were asked about the past 12-month frequency and impact of their experiences of discrimination in a broad range of settings, including family, friends, workplaces and health services. The data were initially analysed using percent frequencies and 95% confidence intervals. A burden score was calculated for each domain, incorporating frequency and impact among those who reported discrimination experiences.
Results
Overall, discrimination in social life was the most common (43.6% [95% CI 41.2, 45.9]), followed by discrimination from family (41.4% [95% CI 39.1, 43.7]) or in making or keeping friends (41.0% [95% CI 38.7, 43.3]). However, the highest burden was from discrimination in finding or keeping a job, in dating/intimate relationships, in housing (including renting or public housing) and in obtaining welfare benefits or disability pensions. The most common type of discrimination experience in the workplace and among friends, family and partners was of people lacking understanding of the impact of the person’s mental health problem. People aged 35–64 years were more likely than those aged 18–34 years to report higher burden in multiple domains; people with depression or attention-deficit/hyperactivity disorder also reported burden in more domains than people with anxiety or severe mental health conditions. Overall, 67.7% (95% CI 65.5, 69.9) agreed that stigma and discrimination was worse than the mental health problem itself.
Conclusions
Our study suggests that reducing the frequency and impact of discrimination in workplaces, welfare benefits and housing should be key targets for policy and practice. Improving the capacity of people in workplaces and intimate partners, families and friendship groups to better understand the impacts of mental health problems on individuals should also be a priority.
Technological similarity enables wine operators to share best practices, benchmark against industry standards, and identify new areas of innovation. Despite this, measuring similarity is notoriously challenging. In this paper, I use sentence embeddings on wine patent data to show how similarity compares across different models. I validate the results both internally and externally, showing large discrepancies in annual trends. The results underscore the importance of selecting suitable models for market assessment, providing a valuable primer for both wine operators and technologists.
On June 19, 2024, the Anti-Money Laundering Regulation (“AMLR”), the Regulation establishing the Anti-Money Laundering Authority (“AMLAR”), and the Sixth Anti-Money Laundering Directive (“AMLD6”) were published in the Official Journal of the EU, signaling a significant shift in the institutional and substantive architecture of anti-money laundering (“AML”) frameworks within the Union. More than simply enhancing existing rules, the new regime introduces innovative solutions to address persistent deficiencies in previous AML/CFT frameworks, particularly the fragmentation across Member States. A notable innovation is the extension of the AML regulatory framework to the professional football sector, which has become increasingly vulnerable to illicit financial activity due to its complex organisation, large financial flows and opaque ownership structures. As a result, professional football clubs and football agents are now subject to AML requirements, including customer due diligence, transaction monitoring and reporting suspicious transactions. This article examines the recently introduced AML obligations for the football sector, navigating the complex regulatory framework and mapping out the underlying requirements. The aim is to increase awareness and understanding of these obligations, thereby aiding football clubs and agents in complying with them and ensuring the integrity of the European football industry.
This article examines attitudes to the law in Menander. It argues that the law is given a specifically Athenian context and that it can give us an insight into the concerns and values of the playwright and his society. By analysing the ways in which characters perceive issues of legality, the article stresses the importance of humanity and personal character in the plays’ dramatization of the interface between private lives and public institutions in early Hellenistic Athens. The article highlights how the ambivalence and the multivocality which are inherent in Menander’s dramatic technique allow for varying responses and for the presentation of radical views.
This article examines how donor requirements affect Civil Society Organisations’ execution of foreign aid initiatives, comparing core and project funding mechanisms in development cooperation. Through a structured, focused comparison of two Latin American CSOs receiving funding from the Swedish International Development Cooperation Agency (SIDA), the research reveals that core funding, contrary to prevailing theories, has a more detrimental impact than project funding due to the nature, timing, and cost of its associated requirements. The analysis identifies variations in stakeholder impact across the aid chain, with intermediary organisations playing significant roles. The findings challenge assumptions about core funding's empowering effects, highlighting how multiple layers of requirements can impede operational effectiveness. The study contributes to scholarly understanding of donor-recipient dynamics while offering practical insights for improving aid delivery mechanisms. It suggests that enhancing aid effectiveness requires not merely simplified requirements, but a fundamental reconsideration of how donors structure their relationships with implementing CSOs.
This research paper addresses the hypothesis that the in vivo criterion of bovine somatic cell count (SCC) < 200,000 cells/ml milk as a diagnostic marker for healthy mammary tissue is not suitable to be adopted to milk samples taken post slaughter. To study immune mechanisms associated with intramammary infections, we developed a mammary explant model. As SCC is routinely applied to differentiate between healthy and inflamed mammary tissue, donor cows were selected based on their milk SCC obtained in vivo. Furthermore, milk cell differentiation for early mastitis detection via flow cytometry allows identification of leucocyte subpopulations and complements SCC. To replace in vivo examination and allow for post mortem selection of donor cows, this explorative study aimed to investigate how slaughter influences the reliability of SCC and differential milk cell count (DMCC) and to assess their validity as diagnostic markers for udder health in bovine milk samples obtained post slaughter. Therefore, quarter milk samples from cows were obtained in vivo and post mortem and analysed to determine SCC and DMCC and identify major mastitis pathogens. The logarithmized numbers of SCC, non-viable cells, viable cells, lymphoid cells, polymorphonuclear (PMN) and large cells per ml milk were compared using linear mixed-effects models in milk samples obtained from cows in vivo and post mortem. The number of lymphoid cells, PMN and large cells was significantly higher in milk samples obtained post mortem than in vivo, with PMN being the most prominent cell population. Higher milk SCC values measured post mortem might be explained by migration of leucocytes into the periphery during slaughter. This should be considered when modelling intramammary infection in vitro using udder tissue. Reflecting these findings, it is not feasible to endorse SCC as a reliable marker for post mortem selection of donor cows with healthy mammary tissue for in vitro models.
The present study experimentally investigates the onset of ventilation of surface-piercing hydrofoils. Under steady-state conditions, the depth-based Froude number $\textit{Fr}$ and the angle of attack $\alpha$ define regions in which distinct flow regimes are either locally or globally stable. To map the boundary between these stability regions, the parameter space $(\alpha , \textit{Fr})$ was systematically surveyed by increasing $\alpha$ until the onset of ventilation while maintaining a constant $\textit{Fr}$. Two simplified model hydrofoils were examined: a semi-ogive with a blunt trailing edge and a modified NACA 0010-34. Tests were conducted in a towing tank under quasi-steady-state conditions for aspect ratios of $1.0$ and $1.5$, and for $\textit{Fr}$ ranging from $0.5$ to $2.5$. Ventilation occurred spontaneously for all test conditions as $\alpha$ increased. Three distinct trigger mechanisms were identified: nose, tail and base ventilation. Nose ventilation is prevalent at $\textit{Fr} \lt 1.0$ and $\textit{Fr} \lt 1.25$ for aspect ratios of $1.0$ and $1.5$, respectively, and is associated with an increase in the inception angle of attack. Tail ventilation becomes prevalent at higher $\textit{Fr}$, and the inception angle of attack exhibits a negative trend. Base ventilation was only observed for the semi-ogive profile, but it did not lead to the development of a stable ventilated cavity. Notably, the measurements indicate that the boundary between bistable and globally stable regions is not uniform and extends to significantly higher $\alpha$ than previously estimated. A revised stability map is proposed to reconcile previously published and current data, demonstrating how two alternative paths to a steady-state condition can lead to different flow regimes.
This paper examines replication research in pragmatics. The paper has three goals: to understand how replication has been used in pragmatics, to explore how replication research can enrich research in pragmatics and language learning, and to offer some suggestions for replication projects in L2 pragmatics. The paper examines sets of original and replicated studies in both L1 and L2 pragmatics to understand the range of research that has been conducted. It then considers the status of item replications (repeated scenarios) that characterize L2 pragmatics research. And it concludes by considering specific issues in L2 pragmatics research that can be insightfully investigated via replication.
Practice research networks (PRNs) have been proposed as a mechanism to support continuous service evaluation and improvement in the field of psychological therapies. In theory, PRNs could help to generate high quality practice-based evidence that has potential to inform and improve clinical care. However, in practice, many obstacles pose challenges to the sustainability and impact of such networks. The UK Northern Talking Therapies PRN is an exemplar that has generated over 20 scientific publications over a decade of successful clinical-academic collaborations. This article distils key lessons learned over that time, to guide and promote the wider adoption of PRNs in psychological services.
On September 17, 2024, a coordinated detonation of approximately 5,000 pager devices in Lebanon produced a large mass-casualty incident. Devices contained pentaerythritol tetranitrate (PETN). We report 5 pediatric patients transferred to a tertiary referral center for management of complex multisystem injuries.
Methods
We performed a brief report of 5 children (<12 years) referred to Baqiyatallah Hospital, Tehran. Demographics, injury pattern, surgical interventions, and short-term outcomes (up to 3 months) were abstracted from medical records. All patients received multidisciplinary care (ophthalmology, plastic surgery, orthopedics, otolaryngology, pediatrics, infectious disease).
Results
Mean age was 9.2 years (range 5–11). All 5 children sustained ocular, facial, and hand injuries. Three eyes were auto-eviscerated, and 4 children underwent partial hand amputations. Multiple operative procedures were required per patient (ocular surgery, facial reconstruction, orthopedic fixation). Early outcomes were poor for vision and hand function in the majority; reconstructive planning and prosthetic rehabilitation were anticipated for longer-term care.
Conclusion
Close-range exposure to small PETN-containing devices produced a distinctive pediatric injury pattern dominated by severe ocular and upper-extremity trauma. These findings emphasize the need for pediatric-focused acute care algorithms and sustained rehabilitation resources after blast incidents.
A low-density jet is known to exhibit global self-excited axisymmetric oscillations at a discrete natural frequency. This global mode manifests as large-scale periodic vortex ring structures in the near field. We experimentally investigate the effectiveness of axial and transverse forcing in controlling such global vortical structures. We apply acoustic forcing at a frequency ($f_{\!f}$) around the natural global frequency of the jet ($f_n$) leading up to and beyond lock-in. Using time-resolved stereoscopic particle image velocimetry, we find that the jet synchronises to $f_{\!f}$ when forced sufficiently strongly. When forced purely axially, the jet exhibits in-phase roll-up of the shear layers, producing axisymmetric vortex ring structures. When forced purely transversely, the jet exhibits anti-phase roll-up of the shear layers, producing tilted vortex ring structures. We find that the former produces relatively strong oscillations, while the latter produces oscillations that are even weaker than those of the unforced case due to asynchronous quenching. We show that the transverse forcing breaks the jet axisymmetry by altering the topology of the coherent structures in the near field, leading to global instability suppression. We also find that the wavelength of the applied forcing has a notable influence on the evolution of vortical structures, thereby modifying the forced response of the jet. The efficacy of transverse forcing and the influence of the forcing wavelength in suppressing the global mode of a self-excited low-density jet present new possibilities for the open-loop control of a variety of globally unstable flows.
The democratic character of Norwegian voluntary organizations is facing tension from rising social inequality and increased demands for specialized expertise. This article explores this tension by examining how social class and individual resources influence board volunteering. We argue that an occupation-based class analysis better captures socioeconomic differences in board volunteering than a resource-theory model by considering both the volume and composition of resources. Using a survey from Norway, we use occupational data to operationalize a scheme that allows us to distinguish class positions according to employment relations and skill requirements. We also control for economic, social, and cultural resources. We find that those in higher-level class positions linked to managerial and socio-cultural occupations, but not technical occupations, are more likely to volunteer on boards. Furthermore, class differences are only partly explained by individual resources, demonstrating that class analysis can complement existing approaches in volunteer research.
Congenital infections cause stillbirth, prematurity, birth defects, and neonatal death, representing a major preventable cause of infant morbidity and mortality. In Brazil, data on their hospital burden remain limited.
Methods:
This retrospective, population-based time series study analyzed hospitalizations of infants (<12 mo) primarily associated with congenital syphilis, toxoplasmosis, rubella, cytomegalovirus, or herpes in Brazil’s Unified Health System (SUS) from 2008 to 2024. Data were extracted from the SUS Hospital Information System (SIH). Hospitalizations were evaluated by annual volume, population-adjusted rates, mean and total costs, intensive care unit (ICU) use, length of stay (LOS), and in-hospital mortality, stratified by region. Temporal trends were examined using Spearman’s correlation and group differences using one-way ANOVA.
Results:
A total of 194,531 hospitalizations were recorded, representing a 394% increase from 4,449 in 2008 to 20,971 in 2024. Congenital syphilis accounted for 88% of admissions and increased across all regions, while toxoplasmosis and cytomegalovirus rose moderately and rubella declined following immunization. National hospital expenditures reached US$49.1 million, rising 170% over the period. Mean LOS decreased modestly (−.8 d), and ICU use remained low except for herpes (up to 32%). In-hospital mortality declined from .73% to .13%, but 29.5% of patients were hospitalized outside their municipality of residence, indicating persistent regional disparities.
Conclusions:
Hospitalizations due to congenital infections—predominantly syphilis—have increased substantially in Brazil, reflecting gaps in prenatal screening, partner management, and maternal–child health coordination. Despite declining mortality, regional inequalities in hospitalization rates, access, and costs persist.
Deception Island is an active, caldera-forming volcano whose surveillance is critically constrained by its extreme Antarctic isolation, scarce resources and limited seasonal human access. This study addresses these challenges by presenting an innovative Global Navigation Satellite Systems (GNSS) geodetic surveillance framework specifically adapted for such a remote environment. Our approach establishes a key operational distinction between non-real-time monitoring and near-real-time surveillance via a semi-continuous wireless network. We effectively resolve the inherent trade-off between promptness and precision by applying signal enhancement methods (e.g. Kalman filtering) to maintain millimetric accuracy in deformation detection, even when utilizing the high sampling rates (1 Hz) essential for rapid assessment. The resulting model allows for the rigorous isolation of the local volcanic signal from the complex regional tectonic kinematics. Crucially, data analysis reveals recurrent 3 year cycles of inflation and deflation in the magmatic system, strongly correlated with seismicity, which validates ground deformation as a reliable volcanic precursor. The primary practical advance is the validation of a dual-term hazard forecasting system: 1) mid-term (months) forecasts based on long-term time-series analysis to facilitate safe inter-campaign operations and 2) short-term (days) forecasting during periods of unrest using ground displacement acceleration, complemented by a magma injection model to predict the spatial location of potential vent openings. This validated and technologically adjusted framework provides an optimized and transferable template for continuous geodetic surveillance in other isolated, active polar volcanoes.
Academic and professional conferences provide opportunities for the dissemination of knowledge, networking, and professional development. Those in more prestigious roles often gain greater visibility, and invited roles in particular make important statements about whose research the profession values most. Conference participation is therefore a source of economic, social, and cultural capital that translates into real opportunities and future career success. In this article, we examine gender representation in the field of archaeology through the lens of participation in the annual meetings of the Society for American Archaeology (SAA). Using archived SAA annual meeting programs from 2002 to 2024, we analyze differences in gender representation across conference roles and participation formats. We find that although women and men are similarly likely to fill self-selected leadership roles, women are less frequently asked to fill invited roles by their peers, particularly when men serve as organizers. We thus argue that gender plays a strong role in determining who occupies positions of prestige and that decisions about who is “qualified” affect distributions of capital within the discipline. We conclude by recommending a series of interventions to session organizers, session participants, and the SAA to help redress gender-based differences in conference participation.
How do institutionalized memories of historical trauma shape contemporary political attitudes? This study examines how emotionally evocative reminders of past violence influence public opinion. Drawing on a survey experiment in South Korea, I test how symbolic narratives of Japanese colonial repression affect emotional responses and downstream political views. The results show that while these reminders evoke strong emotions—especially anger and fear—they do not directly alter attitudes toward national identity or policy. Instead, anger, more than fear, consistently predicts both inclusive orientations, such as increased national pride, and exclusive preferences, including support for protectionist policies. These findings suggest that historical trauma influences political behavior not by providing new information but by activating internalized emotional frameworks. The study contributes to research on the legacy of political violence by identifying discrete emotions as key mechanisms linking collective victimhood to divergent political responses.
This paper examines patterns of volunteering during COVID-19 in different areas of civil society and demographic groups in Denmark. The aim is to understand how differences in the areas of civil society's political resources and organizational settings, and different barriers to volunteering of demographic groups, relate to variation in the levels of volunteering in periods of the pandemic with different lockdown measures. Using two cross-sectional surveys from spring 2020 (n = 3,497), and spring 2021 (n = 1,692), and a four-round panel dataset (n = 1,340), we measure changes in volunteer participation during the first year of the pandemic. We find significant drops in volunteering within most areas. While the level of lockdown correlates strongly with changes in volunteering, differences between areas of civil society point to the importance of variations in political resources and organizational settings for explaining which areas recovered fastest in the re-opening of society. Additionally, declines in volunteering did not differ significantly across demographic groups.
Intra-abdominal infections (IAIs) are common in both the inpatient and outpatient setting but are not often a target for antimicrobial stewardship programs (ASP). However, IAIs provide ASPs an opportunity to translate evidence into practice while also addressing empiric broad-spectrum antibiotic use and establishing relationships with surgical stakeholders. In this review, we analyze five areas of emerging evidence within this heterogeneous field that merit close attention from ASPs, including spontaneous bacterial peritonitis prophylaxis, antibiotic management of appendicitis and biliary tract infections, and optimal amoxicillin-clavulanate and metronidazole dosing.
α-Tocopherol, the most biologically active form of vitamin E, plays a central role in maintaining animal well-being and enhancing performance through its potent antioxidant function. This review explores the nutritional significance of α-tocopherol in animal systems, with a focus on its bioavailability, biopotency, and broader physiological roles. Among the eight vitamin E vitamers, α-tocopherol is preferentially retained and distributed due to its selective binding by hepatic α-tocopherol transfer protein, which facilitates its incorporation into very-low-density lipoproteins and delivery to tissues. Its antioxidant activity is closely linked to its membrane localization, where it scavenges lipid peroxyl radicals and prevents oxidative damage. The tocopheroxyl radical formed in this process can be regenerated in an antioxidant network by co-antioxidants such as vitamin C, preserving its antioxidant capacity. These molecular mechanisms support membrane integrity, immune function, and metabolic stability, especially under oxidative stress conditions common in livestock production. Despite its well-established importance, the bioavailability and biopotency of α-tocopherol are influenced by several factors, such as chemical form, dietary composition, species-specific gastrointestinal physiology, digestive efficiency, tissue distribution, metabolism, and excretion. α-Tocopherol has the highest biopotency of all vitamin E forms. Thereby, natural RRR-α-tocopherol exhibits greater biopotency than synthetic all-rac-α-tocopherol due to stereoisomer-specific differences in tissue distribution and retention. Esterified forms such as α-tocopheryl acetate, though more stable in feed, require enzymatic hydrolysis for absorption affecting bioavailability, which may be impaired in young or stressed animals. Current challenges include the lack of standardized biomarkers for vitamin E status, limited cross-species biopotency data, and insufficient understanding of how environmental and dietary factors modulate utilization and requirements. This review highlights the need for integrative approaches combining pharmacokinetics, tissue deposition, and functional outcomes to improve the precision of α-tocopherol supplementation strategies. Advancing this understanding is essential to fully harness the nutritional power of α-tocopherol in diverse animal production systems.
This article examines the identities of three sub-ethnic and ethnographic groups in Georgia – Adjarians, Megrelians, and Tushetians – and their relationship to the Georgian nation in political and ethnic terms. Drawing on fieldwork conducted between 2022 and 2023, the study explores how these groups navigate their distinct cultural markers, such as religion, language, and traditions, while engaging with the broader national identity. Using the theoretical framework of nationalization, the analysis explores four key themes: the salience of ethno-cultural differences, the transformation of sub-ethnic identities, the politicization of ethno-cultural markers, and the groups’ historical narratives emphasizing their contributions to Georgian-ness. The findings highlight the link between local identities and national integration. The findings contribute to broader theoretical debates on nationalization by demonstrating that the integration of sub-ethnic groups is not a unidirectional process of homogenization, but a dynamic negotiation of diversity and unity.