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Chapter 4: Brain Development

Chapter 4: Brain Development

pp. 84-113

Authors

, University of California, Merced, , University of California, Berkeley
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Extract

This chapter provides an exploration of brain development, with a strong emphasis on essential learning goals. We start with an infant born at term, where the foundational brain structure is already established, and most neurogenesis is complete by the end of the first postnatal year. However, childhood is a critical phase for brain development, marked by increased energy allocation. Our examination highlights the vital interplay between genes and the environment in shaping the brains trajectory. Neither can independently dictate outcomes; instead, brain development unfolds as a dynamic and adaptable process within genetic boundaries. We commence by introducing fundamental brain anatomy concepts, laying the foundation for a comprehensive understanding of development. Subsequently, we embark on a journey from the first neural cell to the newborn, elucidating the emergence, pathways, and connections of nerve cells. Finally, we summarize postnatal changes, drawing insights from histology and structural MRI, revealing the ongoing marvels of brain growth while remaining focused on our core learning objectives.

Keywords

  • epigenetic landscape
  • canalization
  • neural development
  • brain development
  • gastrulation
  • neurulation
  • myelination
  • synaptic pruning

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