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Timing of food intake seems to impact metabolism and circadian rhythms, and eating in synchronisation with the rhythms has been suggested to be favourable for health. This study aims to evaluate temporal meal patterns in the Swedish population and explore differences between population groups. Further, to investigate whether temporal meal patterns are associated with energy and nutrient intake, data were sourced from two national dietary surveys Riksmaten Adolescents 2016–2017 and Riksmaten Adults 2010–2011, with a total of 4763 participants. Food intake and temporal meal patterns were measured with 3- to 4-day food diaries and/or 24-hour recalls. The average meal frequency was 4·2 eating occasions (sd 0·9) per day for adolescents with an eating window of 11·9 h (sd 1·7). For adults, it was 4·6 (sd 1·1) eating occasions and an eating window of 12·0 h (sd 1·9) Meal frequency was positively associated with energy intake in both adolescents (r = 0·47) and adults (r = 0·51). Meal frequency was higher with age, and adolescents skipped breakfast more often, and had a later energy distribution than adults. A higher eating frequency and eating breakfast are associated with a higher absolute intake of whole grains, as well as Vitamin D and folate. A higher eating frequency makes it more likely to reach nutrient requirements. However, a higher eating frequency was also associated with a higher intake of free sugars. The findings can serve as reference data for temporal meal patterns in the Swedish context and also show differences within a population, which can be valuable insights for public health nutrition.
This study aimed to assess the impact of hypertensive disorders of pregnancy on infant neurodevelopment by comparing 6-month and 2-year psychomotor development outcomes of infants exposed to gestational hypertension (GH) or preeclampsia (PE) versus normotensive pregnancy (NTP). Participating infants were children of women enrolled in the Postpartum Physiology, Psychology and Paediatric (P4) cohort study who had NTPs, GH or PE. 6-month and 2-year Ages and Stages Questionnaires (ASQ-3) scores were categorised as passes or fails according to domain-specific values. For the 2-year Bayley Scales of Infant and Toddler Development (BSID-III) assessment, scores > 2 standard deviations below the mean in a domain were defined as developmental delay. Infants (n = 369, male = 190) exposed to PE (n = 75) versus GH (n = 20) and NTP (n = 274) were more likely to be born small for gestational age and premature. After adjustment, at 2 years, prematurity status was significantly associated with failing any domain of the ASQ-3 (p = 0.015), and maternal tertiary education with increased cognitive scores on the BSID-III (p = 0.013). However, PE and GH exposure were not associated with clinically significant risks of delayed infant neurodevelopment in this study. Larger, multicentre studies are required to further clarify early childhood neurodevelopmental outcomes following hypertensive pregnancies.
We outline a framework for comparative analyses of minority education and present four illustrative Central and Eastern European (CEE) cases: Bulgaria, Estonia, the Republic of North Macedonia and Romania. The fourfold typology we develop relies on literature on minority rights and diversity management and proposes a holistic approach, differing from narrower legal analysis. We investigate education as part of larger macro-approaches of minority policies and focus on the interrelation between educational equity and identity reproduction. In our case studies, we employ a diachronic perspective, focusing on historical dynamics and pathways of educational policies, aiming to identify both gradual change and more radical shifts in institutional processes. The concept of de facto discrimination plays an important role as well: next to the historical analysis of legislative and policy changes, we use various statistics to measure educational equity. We rely on the 2022 PISA results, a tool popular in the comparative research of educational systems but underutilized in the fields of minority rights and minority policies. In our comparative inquiry, we argue that the educational systems of CEEs diverge in terms of minority identity reproduction, but few of them can be labelled as integrative, as intercultural elements are rather weak, while education usually fails to provide equity for minority students.
Actigraphy provides an objective measure of sleepiness and is recommended by the American Academy of Sleep Medicine for use 7–14 days prior to multiple sleep latency testing. It plays a valuable role in the differential diagnosis of hypersomnolence.
Objective:
Our aim was to provide a comprehensive summary of actigraphy features in central disorders of hypersomnolence (CDH).
Methods:
Data were sourced from six bibliographic databases. Fixed- or random-effects models were applied to compare patients with narcolepsy type 1 (NT1) to controls.
Results:
Of the 1,737 publications identified in our search, 8 studies met the inclusion criteria. The total sample consisted of 473 participants, encompassing patients with NT1, idiopathic hypersomnia (IH), hypersomnolence with normal CSF hypocretin-1 levels, Kleine–Levin syndrome (KLS), traumatic brain injury (TBI), major depressive disorder (MDD), myotonic dystrophy (MD), primary insomnia and healthy controls. Actigraphy devices varied across studies. Compared to control subjects, NT1 patients had lower total sleep time (TST), sleep efficiency and daytime motor activity, with increased wake after sleep onset, awakenings, nocturnal motor activity and longest nap duration. In KLS, TST was higher during hypersomnia episodes than during asymptomatic phases. TBI and MDD patients had a higher TST than the control group, while MD patients had a lower TST than patients with IH.
Conclusions:
Actigraphy is a valuable tool for objectively assessing sleep and can assist in detecting CDH. However, the absence of standardized guidelines limits their broader implementation in clinical practice.
The article investigates perceived and objective inequalities in Bosnia and Herzegovina, focusing on Republika Srpska amid rising societal tensions, bolstering the secession narrative, and political mobilization. Aimed at identifying objective inequalities that might fuel grievances causing societal upheaval, the findings reveal no significant disparities between Republika Srpska and the Federation of Bosnia and Herzegovina. Despite the absence of objective economic, social, or political inequalities, a perception of disparity persists among Bosnian Serbs, driven by the nationalist rhetoric of local leaders. Hence, the research underscores the gap between perceived inequalities and objective disparities, challenging conventional beliefs about the causal chain from objective horizontal inequalities to social mobilization by demonstrating how unfounded grievances can still drive tensions and secessionist agendas.
We study long-run inflation in a competitive-search model with heterogeneous agents. Under competitive search, individuals’ matching-probability (extensive) margins trade off against quantity (intensive) margins. With money and unfettered market participation, these trade-offs depend on inflation and individuals’ heterogeneous money holdings. We find that welfare falls as inflation increases. However, money-holdings inequality is not monotonic in inflation. As inflation rises, liquid-wealth inequality first falls. For sufficiently high inflation, the overall extensive-margin effect dominates the intensive margin, and liquid-wealth inequality rises. The model also poses a new computational challenge to which we propose a novel solution method.
Scholars have paid minimal attention to the political and practical objectives that guided Tuskegee Institute’s sociological program and institutional interventions in the nineteenth and twentieth centuries. Leveraging a multi-modal, historical sociological approach grounded in primary and secondary analyses of biographical data, narratives, and archival data, I show that Tuskegee’s institutional interventions illustrate three abolitionist tactics: (1) building consciousness through research dissemination and place-based investment, (2) galvanizing Southern Whites and political elites to abolish lynching locally, and (3) countering the propaganda used to justify lynching to inspire divestment from lynching and carceral punishment. Booker T. Washington’s commitment to eradicating structural racism and resource deprivation in the aftermath of slavery led to Tuskegee Institute’s formation of the first department of applied rural sociology in the United States, and the Negro Farmers’ conference and Movable School interventions supported a comprehensive anti-poverty strategy. Likewise, the research activism of Monroe Work, disseminated via The Negro Year Book and individual publications, sought to galvanize the abolition of lynching and carceral punishment. In the wake of re-emerged visibility of White supremacist terrorism and commitments to practicing Du Boisian sociology across the United States, I argue that reviving the memory of Tuskegee’s institutional practices makes a case for reconsidering the place of abolition in academic sociology in the twenty-first century.
Connectivity and trade dominate discussions of the Mediterranean Bronze and Iron Ages, where artefacts travelled increasing distances by land and sea. Much of the evidence for the means through which such networks operated is necessarily indirect, but shipwrecks offer direct insights into the movement of goods. Here, the authors explore three Iron Age cargoes recently excavated at Tel Dor on the Carmel Coast, the first from this period found in the context of an Iron Age port city in Israel. Spanning the eleventh–seventh centuries BC, these cargoes illuminate cycles of expansion and contraction in Iron Age Mediterranean connectivity and integration.
Neuromodulation is emerging as a promising intervention for intractable pain syndromes. Despite heterogeneous outcomes in the literature, motor cortex stimulation (MCS) has proven effective in addressing chronic orofacial pain. Painful trigeminal neuropathy (PTN) is characterized by constant facial pain and somatosensory signs. Refractory cases, unresponsive to medical and surgical therapies, significantly impact quality of life and pose socioeconomic challenges. This article presents a retrospective case series of five MCS patients who were treated for refractory PTN in Atlantic Canada.
Methods:
Since 2021, eight cases of refractory PTN from Atlantic Canada have been recruited. Demographic and clinical characteristics were collected, with primary and secondary outcomes respectively defined as a 50% Visual Analogue Scale (VAS) reduction and a 60% reduction in morphine equivalent dose per day (MED, mg/day) at 12 months post-operation. Pain intensity was assessed preoperatively and at 6- and 12-month follow-ups, along with eating habits, return to work, and global satisfaction.
Results:
Five patients with refractory PTN were implanted with MCS, all of whom achieved the primary and secondary outcomes. Preoperatively, mean VAS was 8.4 ± 1.0, reduced to 2.0 ± 1.1 at 12 months post-MCS, corresponding to a 77 ± 13% pain reduction. Average MED/day was reduced by 93 ± 13%, with 60% of participants narcotic-free at 12 months and 80% at 18 months. There were no immediate or delayed complications related to the MCS procedure.
Conclusion:
MCS exhibits significant potential for long-term pain relief and reducing opioid consumption in refractory trigeminal pain, emphasizing the necessity for large national multicenter trials.
Closed-form expressions for aerodynamic force on an accelerating aerofoil were presented in the 1930s, relating instantaneous force to geometric and kinematic parameters under the following assumptions: a thin aerofoil, small-amplitude motions, planar wake development, and a flow that is inviscid, incompressible and two-dimensional. The present work is a step towards analogous closed-form expressions for large-amplitude motions of thick foils when the flow remains attached and boundary-layer thickness approaches (but does not equal) zero. A mathematical framework is derived from vortical flow theory to highlight the finite degrees of freedom that must be solved or predicted in order to yield a predictive aerodynamic model under the stated conditions. The special case of periodic motion is further considered, and an equation is derived to calculate mean forces from known or assumed time histories of circulation, vorticity-weighted mean wake convection velocity and trailing-edge velocity.
The quasi-geostrophic two-layer model is a widely used tool to study baroclinic instability in the ocean. One instability criterion for the inviscid two-layer model is that the potential vorticity (PV) gradient must change sign between the layers. This has a well-known implication if the model includes a linear bottom slope: for sufficiently steep retrograde slopes, instability is suppressed for a flow parallel to the isobaths. This changes in the presence of bottom friction as well as when the PV gradients in the layers are not aligned. We derive the generalised instability condition for the two-layer model with non-zero friction and arbitrary mean flow orientation. This condition involves neither the friction coefficient nor the bottom slope; even infinitesimally weak bottom friction destabilises the system regardless of the bottom slope. We then examine the instability characteristics as a function of varying slope orientation and magnitude. The system is stable across all wavenumbers only if friction is absent and if the planetary, topographic and stretching PV gradients are aligned. Strong bottom friction decreases the growth rates but also alters the dependence on bottom slope. In conclusion, the often mentioned stabilisation by steep bottom slopes in the two-layer model holds only in very specific circumstances, thus probably plays only a limited role in the ocean.
Traumatic brain injury (TBI) is associated with negative sequelae affecting sensorimotor and executive functions. Conversely, age-related decline in these functions is also well documented. The current study examined the accelerating aging hypothesis by assessing vision, fine motor skills and executive function in older individuals with a history of TBI. It was hypothesized that the age-related reduction in function would be exacerbated in individuals with TBI.
Methods:
Participants (n = 27) were community-dwelling older adults (mean age 74.6 years, SD 6.8; 14 females). The history of TBI was determined using the Ohio State University TBI Identification Method (n = 13). The visual examination included visual acuity, contrast sensitivity and binocular vision. Visuomotor control was assessed using a precision grasping and placement task. The antisaccade task was used to evaluate executive functions. Participants with a history of TBI also completed questionnaires assessing quality of life.
Results:
There were no significant differences between the groups for the vision tests or fine motor skill assessment. In contrast, the oculomotor test revealed significantly longer saccade latency in the group with a history of TBI (10%–12% difference, p < 0.05). Exploratory analysis showed a significant negative association between the antisaccade latency and lower participation score on the Sydney Psychosocial Reintegration Scale.
Conclusions:
Results indicate that oculomotor testing is a sensitive behavioral assay of executive functions in older adults and differentiates between healthy adults and those with a history of TBI. The significant saccade latency slowing supports the accelerating aging hypothesis, while the association with community participation suggests an impact on lifestyle.
Some theorists and practitioners argue that public schools in liberal democracies should teach students to be engaged, participatory citizens. Others argue that schools function as disciplinary training grounds, producing docile workers and obedient members of society. How can we reconcile these normatively different views? In exploring this question, we analyze school documents from a national random sample of U.S. public charter schools, examining the terms schools use most frequently and how schools discuss normative conceptions of citizenship. Using text-as-data methods and qualitative analysis, we suggest that both models appear in U.S. schools, but are implemented largely along racialized lines, with majority White schools tending to emphasize democratic values and majority non-White schools emphasizing obedience.
This study investigates the caregiver–child relationship as a proximal risk factor in the transactional development of youth personality pathology. 129 girls (aged 11–13 years), two-thirds of whom were oversampled for shy and fearful temperament, and their primary caregiver, participated in laboratory-based conflictual interactions. Trained observers rated positive and negative escalation, mutuality, relationship quality, and satisfaction. Concurrently and two years later, girls’ maladaptive traits were assessed via self- and caregiver-reports based on the DSM-5 Alternative Model for Personality Disorders (AMPD) domains (negative affect, detachment, antagonism, disinhibition, and psychoticism). Using a series of path models, we assessed whether dyadic interactions predicted changes in maladaptive traits. In dyads exhibiting reduced positive interaction patterns, specifically a lack of mutuality and relationship satisfaction, we observed increases in girls’ negative affect, detachment, disinhibition, and psychoticism. These patterns were more pronounced in girls’ self-reports. Negative escalation predicted girl- and caregiver-rated increases in antagonism. The study illustrates the importance of the caregiver–child relationship in the etiology of developmental personality pathology by establishing a link between observed caregiver–adolescent interactions and prospective changes in key domains of maladaptive traits. It expands the literature on dyadic interaction and developmental personality pathology to the dimensional framework of the AMPD.
Removing liquid from a channel is an important process. In a horizontal slit in the presence of a downward gravity field, two distinct liquid states were commonly observed: gravity-driven liquid non-occlusion and liquid plug (Parry et al. 2012 Phys. Rev. Lett.108, 246101). A wetting-driven non-occlusion at some contact angles was induced by insertion of a rod into a horizontal tube at an eccentric position (Tan et al. 2022 J. Fluid Mech.946, A7). Insertion of a plate into a horizontal slit may enhance the capacity of removing liquid. This situation is theoretically investigated, and the theoretical results are mutually verified by a computational fluid dynamics (CFD) numerical method that is first employed to determine the critical non-occlusion conditions. Four types of liquid states are observed. The effects of contact angles, plate position and Bond number (measured by downward gravitational force relative to surface tension force) on different types of liquid states are analysed. This paper additionally provides a CFD numerical method for understanding the conditions for the stability and existence of the liquid plugs in complex situations (e.g. considering the effect of the sidewalls, or when a rod or plate is inserted into a circular, elliptical or polygonal tube) in the future.
Let M be a smooth closed oriented surface. Gaussian thermostats on M correspond to the geodesic flows arising from metric connections, including those with non-zero torsion. These flows may not preserve any absolutely continuous measure. We prove that if two Gaussian thermostats on M with negative thermostat curvature are related by a smooth orbit equivalence isotopic to the identity, then the two background metrics are conformally equivalent via a smooth diffeomorphism of M isotopic to the identity. We also give a relationship between the thermostat forms themselves. Finally, we prove the same result for Anosov magnetic flows.