The crystal structure of anisomycin, C14H19NO4, has been solved and refined using synchrotron X-ray powder diffraction data, and optimized using density theory functional techniques. Anisomycin crystallizes in the space group P212121 (#19) with a = 5.80382(4), b = 8.58149(6), c = 28.63508(26) Å, V = 1,426.183(27) Å3, and Z = 4 at 298 K. The crystal structure consists of layers of anisomycin molecules parallel to the ab-plane. The molecules form zig-zag chains of N–H···O and O–H···N hydrogen bonds along the a-axis. The powder pattern has been submitted to the International Centre for Diffraction Data for inclusion in the Powder Diffraction File™ (PDF®).

This article argues that a public education in method—specifically, close reading—is the only viable role for literary studies within the public humanities. Drawing on recent discussions about the uses of the public humanities—and setting itself against recent interventions that have proclaimed a different public role for public literary studies—this article takes the form of an overt but minimalist manifesto: it tries to make the minimal case for public literary studies that is sufficient to give it a public usefulness. In so doing, it breaks down previous efforts of understanding the utility of literary studies as related to literature’s utility, but also to large-scale interventionist ideals such as climate-change activism. It proposes close reading as training in public debate, as an exercise towards better public meaning-making, and thus as a signal contribution to the making of better democratic citizens in a deliberative public sphere.

We analyze generating functions for trees and for connected subgraphs on the complete graph, and identify a single scaling profile which applies for both generating functions in a critical window. Our motivation comes from the analysis of the finite-size scaling of lattice trees and lattice animals on a high-dimensional discrete torus, for which we conjecture that the identical profile applies in dimensions $d \ge 8$.

We describe the findings of cyclidans from the unpublished collection of the famous paleontologist B.I. Chernyshev (1888–1950) in the storage of the Academician F.N. Chernyshev Central Scientific Research Geological Survey Museum (CNIGR museum, St. Petersburg, Russia). These cyclidans were discovered by various researchers in the Carboniferous and Permian of the Urals. They are represented by the following taxa: Oonocarcinus uralicus new species, Uralocyclus feldmanni new species, Ambocyclus capidulum (Chernyshev, 1933), and Magnitocyclus (?) sp. indet. The discovery of the new species Oonocarcinus uralicus n. sp. greatly expands the geographic and stratigraphic interval of the genus Oonocarcinus Gemmellaro, 1890, previously known from the Middle Permian and Triassic. The discovery of Uralocyclus feldmanni n. sp. in the Mississippian deposits of the Chelyabinsk Oblast indicates a wide distribution of the genus Uralocyclus Mychko and Alekseev, 2018 in the Early Carboniferous, because Carboniferous representatives of this genus were previously known only from Ireland and England. The paper provides an up-to-date list of all known cyclidan occurrences and taxa in Russia.

http://zoobank.org/6d69be36-74ca-4205-8eb8-89d1f28458c7

Phenelzine sulfate crystallizes in the space group P21/c (#14) with a = 20.7418(15), b = 5.51507(5), c = 20.6038(11) Å, β = 109.5490(25)°, V = 2,221.06(9) Å3, and Z = 8 (Ẓ̣′ = 2) at 298 K. The crystal structure consists of supramolecular double layers of cations and anions parallel to the bc-plane. The inner portion of the layers consists of the charged parts of the cations and the anions, whereas the outer surfaces consist of phenyl rings, with van der Waals interactions between the layers. The sulfate anions stack along the c-axis. Each N–H acts as a donor to at least one sulfate O atom, and each O atom acts as an acceptor in at least one N–H···O hydrogen bond. The powder pattern has been submitted to the International Centre for Diffraction Data for inclusion in the Powder Diffraction File™ (PDF®).

This study presents the black hole accretion history of obscured active galactic nuclei (AGNs) identified from the JWST CEERS survey by Chien et al. (2024) using mid-infrared (MIR) SED fitting. We compute black hole accretion rates (BHARs) to estimate the black hole accretion density (BHAD), $\rho_{L_{\text{disk}}}$, across $0 \lt z \lt 4.25$. MIR luminosity functions (LFs) are also constructed for these sources, modeled with modified Schechter and double power law forms, and corresponding BHAD, $\rho_{\text{LF}}$, is derived by integrating the LFs and multiplying by the luminosity. Both $\rho_{\text{LF}}$ extend to luminosities as low as $10^7 \, {\rm L}_{\odot}$, two orders of magnitude fainter than pre-JWST studies. Our results show that BHAD peaks between redshifts 1 and 3, with the peak varying by method and model, $z \simeq$ 1 - 2 for $\rho_{L_{\text{disk}}}$ and the double power law, and $z \simeq$ 2 - 3 for the modified Schechter function. A scenario where AGN activity peaks before cosmic star formation would challenge existing black hole formation theories, but our present study, based on early JWST observations, provides an initial exploration of this possibility. At $z \sim 3$, $\rho_{\text{LF}}$ appears higher than X-ray estimates, suggesting that MIR observations are more effective in detecting obscured AGNs missed by X-ray observations. However, given the overlapping error bars, this difference remains within the uncertainties and requires confirmation with larger samples. These findings highlight the potential of JWST surveys to enhance the understanding of co-evolution between galaxies and AGNs.

A major debate is underway in China on a proposed law that would grant new rights to Chinese workers. The debate has not been widely reported outside of China; until recently it has been almost entirely ignored by media in the United States. But when the Chinese government opened a 30-day public comment period this spring, it received nearly 200,000 comments, the majority from ordinary workers. But some comments also came from big U.S.- and European-based global corporations and their lobbying groups. These powerful forces squarely opposed the new law.

Wal-Mart's recent agreement to recognize unions in China has made headlines worldwide. But Wal-Mart and other corporations, including Google, UPS, Microsoft, Nike, AT&T, and Intel, have acted through the American Chamber of Commerce in Shanghai (AmCham) and other industry associations to try to block Chinese legislation that would significantly increase the power and protection of workers.

We present an analysis of the hard X-ray emission from the central region of Abell 3667 using deep NuSTAR observations. While previous studies on the nature of the hard X-ray excess have been controversial, our analysis of the central region suggests that the excess is primarily thermal, best described by a two-temperature (2T) model, with the high-temperature component likely arising from merger-induced heating. This interpretation contrasts with some earlier suggestions of non-thermal emission due to inverse Compton scattering of relativistic electrons. Additionally, we set a lower limit on the magnetic field strength of $\sim 0.2 \, \unicode{x03BC}$G in the central region, consistent with values found in other dynamically active clusters and compatible with those inferred from equipartition and Faraday rotation measurements. Since our study is focused on the central region of the cluster, further high-resolution observations of the outer regions will be critical to fully disentangle the thermal and non-thermal contributions to the X-ray.

Political Equality is the view that, in political matters, everyone should have an equal say. Political Sufficiency is the view that, in political matters, everyone should have enough of a say. Whereas Political Equality is concerned with relativities, Political Sufficiency is a matter of absolutes. It is natural to assume that, to justify ‘one person, one vote’, we must appeal to Political Equality. We argue that this is not the case. If Political Equality justifies ‘one person, one vote’, so does Political Sufficiency. Moreover, there is reason to prefer Political Sufficiency to Political Equality.

The unavailability of reliable, easy-to-use depression screening tools adapted for Sub-Saharan African children is a significant barrier to the treatment of childhood depression. We thus adapted the Child Depression Screening Tool (CDST) to the South African (SA), Senegalese (S) and Rwandan (R) contexts, as a tool to screen for depression in children suffering from chronic illnesses, trauma and difficulties related to COVID-19, family and community hardships. A DSM-5-based diagnostic interview and the CDST screening measure were administered to 1,001 participants aged between 7 and 16 years. The prevalence of depression ranged between 9.5 and 16.8%. It was more prevalent in youth with chronic illness and those exposed to adverse life events. Older age (R and SA), female sex (S), dislike of school (R and SA) and cannabis use (SA) were also associated with worse depression. Receiver operating characteristic analysis showed satisfactory performance (79-89%) and that sensitivity and specificity were optimized at a CDST cut-point of 5.0. The CDST is a valid tool to screen for depression in the settings assessed. If found to be suitable in other countries and settings, it may offer a clinically sound, sustainable path towards the identification of child depression in Africa.

This study assessed the association between home learning environment (HLE) at 3 years of age and children’s concurrent and longitudinal vocabulary skills. HLE consisted of the following activities done with primary caregivers: storytelling, drawing, music, toys and games, everyday home activities, playing outdoors, and reading. Results demonstrated that a higher HLE score at 3 years was concurrently related to higher expressive vocabulary and grammar scores, and longitudinally to higher receptive language scores from 5 to 9 years of age. Taken together, these findings suggest that children’s HLE represents a significant contributor to children’s concurrent and longitudinal language skills.

The article focuses on the Ukrainian official language policies and their impact on Ukrainian people-building, claiming the state promotion of Ukrainian as an exclusive language of public life and the ethnically-based understanding of the Ukrainian people, inevitably lead to the exclusion of non-Ukrainian communities from participation in democratic processes, politicise the already problematic language situation and risk undermining the role of Ukrainian as an official language.

For such an analysis, and a conceptualisation of how the state can shape the nature of the people, the article proposes a new theoretical understanding of the people as an organisational system, based on a functional adaptation of Niklas Luhmann’s social systems theory and Charles Taylor’s social imaginary.

Who should decide a scientist’s research agenda? The scientist him- or herself? Superiors, such as science ministries or university management? Sponsors, such as funding organizations or industry? Interest groups, such as churches, political parties, animal rights organizations or patient initiatives? What is the right balance between the scientist’s autonomous decision on the one hand and players’ interests on the other? These questions will not be answered here, but reflected upon with regard to the difficult trade-offs involved and the threats to scientific freedom that can result from them. For this purpose, I propose an analytical framework that conceptualizes the thematic autonomy of science as a gradual interplay of individual choices of research topics made in the context of the respective scientific community, on the one hand, and external constraints, on the other. With regard to them, seven basic levers will be distinguished. This framework will be applied to the current state of German professors’ freedom to choose their research agenda.

Common mental disorders (CMDs) are a leading cause of burden and disability globally. Approximately 75% of those living with CMDs reside in low- and middle-income countries (LMICs), and up to 90% of those needing mental health care do not receive it. The Friendship Bench is a task-sharing mental health intervention delivered by lay health workers (LHWs) that utilizes concepts of Problem-Solving Therapy. The aim of this systematic review is to identify and evaluate the barriers and facilitators to the implementation of research outcomes of the Friendship Bench and understand its systematic uptake to narrow the CMD treatment gap. We conducted a systematic review of articles that reported on the Friendship Bench in LMICs, CMDs, implementation research outcomes, and studies that utilized experimental, observational, or qualitative study designs. We identified articles using medical subject headings and keywords from APA PsycINFO, Cochrane, CINAHL, EMBASE, Global Health, OVID, PubMed/Medline, Science Direct, Web of Science, and Google Scholar in February 2023 and again in December 2023 to capture any additional articles. We screened 641 articles, and a total of 7 articles were included in the final analysis. All studies were conducted in Zimbabwe within the past 8 years, and across all the studies, all implementation research outcomes were reported. There is strong evidence that the Friendship Bench is acceptable, appropriate, and feasible to address the CMD treatment gap in Zimbabwe. Facilitators include that the Friendship Bench is culturally adaptable, utilizes trusted LHWs, and has relatively strong community and political buy-in. Conversely, barriers include a lack of a reliable mental health system, limitations in its ability to treat more serious mental conditions, and mental health stigma. There is an opportunity to explore the application of the Friendship Bench for CMDs in other countries and as a basis for novel task-sharing interventions for other health conditions.

The Paragaricocrinidae is an enigmatic late Paleozoic family of camerate crinoids that retained a robustly constructed calyx more typical of Devonian to Early Mississippian crinoids. The discovery of the oldest member of this family, Tuscumbiacrinus madisonensis n. gen. n. sp., initiated a phylogenetic investigation of the Paragaricocrinidae and consideration of its diversification and paleobiogeographic distribution. Phylogenetic analyses demonstrate the need to describe Tuscumbiacrinus n. gen and conduct revisions to preexisting taxa, resulting in the description of Palenciacrinus mudaensis n. gen. n. sp.; Pulcheracrinus n. gen.; Nipponicrinus hashimotoi n. gen. n. sp.; and Nipponicrinus akiyoshiensis n. gen. n. sp. Megaliocrinus exotericus Strimple is reassigned to Pulcheracrinus n. gen. In addition to having an anachronistic morphology, relatively few specimens are known through the ca. 76-million-year duration of this family. This pattern is unlikely to have resulted from low fossil sampling alone, and instead likely reflects low abundance and/or taxonomic richness of a long-lived waning clade. From its apparent origination in Laurussia during the Mississippian, the Paragaricocrinidae diversified into a cosmopolitan clade. Following a diversity drop during the Pennsylvanian, the Paragaricocrinidae persisted but exemplified characteristics of a dead clade walking until its eventual extinction during the middle Permian (Wordian).

http://zoobank.org/3e5df71c-112f-4556-96c5-a5a62d4a4da9

Herodotus’ depiction of Miltiades’ transgression in the sanctuary of Demeter Thesmophoros on Paros is marked by the intriguing phrase κινήσοντά τι τῶν ἀκινήτων (6.134.2). We examine this proverbial phrase, whose implications for Herodotus’ portrayal of Miltiades’ downfall have not yet been fully acknowledged. The article draws attention to the widespread concept of sacred immovables (ἀκίνητα) that were protected by imprecations, and suggests that Miltiades triggered a contingent curse protecting divine property. Herodotus configures the episode of Miltiades on Paros as a narrative of entrapment and steers his readers to view Miltiades’ fate as the consequence of a curse at work.

Upper-limb occupational exoskeletons reduce injuries during overhead work. Previous studies focused on muscle activation with and without exoskeletons, but their impact on shoulder fatigue remains unclear. Additionally, no studies have explored how exoskeleton support levels affect fatigue. This study investigates the effects of assistive profiles on muscular and cardiovascular fatigue. Electromyographic (EMG) and electrocardiographic signals were collected to compute EMG median frequency (MDF), heart rate (HR), and heart rate variability (HRV). Fatigue was assessed using three MDF and HR metrics: relative change ($ {\mathrm{MDF}}_{\Delta} $,$ {\mathrm{HR}}_{\Delta} $), slope ($ {\mathrm{MDF}}_{\mathrm{slope}} $,$ \mathrm{H}{\mathrm{R}}_{\mathrm{slope}} $), and intercept ($ {\mathrm{MDF}}_{\mathrm{intercept}} $,$ \mathrm{H}{\mathrm{R}}_{\mathrm{intercept}} $) of the linear regression. Results showed$ {\mathrm{MDF}}_{\Delta} $decreased 64% (p = 0.0020) with higher assistance compared to no exoskeleton; $ {\mathrm{HR}}_{\Delta} $ decreased 40% (p < 0.0273) with lower assistance, $ {\mathrm{MDF}}_{\mathrm{slope}} $ decreased up to 67% (p = 0.0039) and $ \mathrm{H}{\mathrm{R}}_{\mathrm{slope}} $ by 43% (p < 0.0098) with higher and medium assistance. HRV metrics included root mean square of successive differences (RMSSD) and low-frequency to high-frequency power ratio (LF/HF). RMSSD indicated parasympathetic dominance, while rising LF/HF ratio suggested physiological strain. Findings support occupational exoskeletons as ergonomic tools for reducing fatigue.

This study focuses on women’s hunger demonstrations and lootings in occupied Antwerp in May 1941. These actions were not just expressions of social discontent but also political actions in the form of illegal propaganda against the occupier. Through specific cases of demonstrations and looting, the first part of this article explores the pattern of these actions and the involvement of participants, local and German police and mayors. The second part provides a general picture of women’s demonstrations and lootings in Belgium and Antwerp, discussing the chronology and repression of these actions and the social profile of the participants. This article tells the story of resistance by working-class women, a perspective still largely absent from resistance historiography. It shows how an explicit female perspective allows us to write a history of female resistance.