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Children with cyanotic CHD experience chronic hypoxaemia and recurrent medical interventions that may adversely affect health-related quality of life.
Aims:
To compare health-related quality of life between children with cyanotic CHD and healthy peers in Sulaimani, Iraq.
Methods:
A hospital-based case–control study was conducted between October 2023 and April 2024, including 200 children with cyanotic CHD and 200 age- and sex-comparable healthy controls aged 3–13 years. Quality of life was assessed using the Pediatric Quality of Life Inventory (PedsQL™), including the Generic Core Scale Version 4.0 and the Cardiac Module Version 3.0, through parent-reported interviews. Group differences were examined using independent-samples t-tests and analysis of covariance, adjusting for age, sex, peripheral oxygen saturation (SpO2), and educational level.
Results:
Children with cyanotic CHD had significantly lower health-related quality-of-life scores across all domains compared with healthy children (all p-values < 0.001). After adjustment, the largest differences were observed in physical functioning and total quality of life, with large effect sizes (partial η2 = 0.50 and 0.63, respectively). Mean SpO2 levels were also significantly lower among children with cyanotic CHD (p < 0.001).
Conclusions:
Cyanotic CHD was independently associated with substantial impairment in quality of life across physical and psychosocial domains. Lower peripheral oxygen saturation (SpO2) was independently associated with poorer health-related quality of life. These findings support integrating health-related quality-of-life assessment and multidisciplinary care into the routine management of children with cyanotic CHD.
When religion and politics become entangled with each other, which one has the upper hand? Do politicians simply instrumentalize religion for their own purposes? Or does involvement with religion constrain what politicians can get away with? If it does, is that because of the content of religious doctrine? Or is it simply because religious movements, like any other coordinated movements of citizens, have political weight?
Addicts, an already vulnerable population, can be made worse off by certain kinds of popular and well-intentioned research programs and beliefs about addiction, agency, and responsibility. Perspectives of backwards-facing responsibility that focus on blameworthiness and liability highlight the injustices that addicts have faced. Likewise, the disease model of addiction, pursued as an alternative to the stigmatization and moralization of the choice model, takes responsibility away from the addict. However, each of these fails to help the addict to recover or to care for herself. If anything, embracing these perspectives and models can rob addicts of agency and lead them to further suffering. Drawing on feminist philosophy, this paper shows there is good evidence for us to reconsider those models and perspectives, and instead ask what kind of understandings about addiction aid in fostering agency and recovery.
L’affaire Canada et Pays-Bas c Syrie devant la Cour internationale de Justice (CIJ) repose sur des accusations de violations systématiques de la Convention contre la torture et autres peines ou traitements cruels, inhumains ou dégradants par la Syrie. Ces violations s’inscrivent pourtant dans un contexte également marqué par des atteintes massives au droit international humanitaire (DIH), qui ne font toutefois pas l’objet de la procédure engagée devant la Cour. Cette absence soulève une question: pourquoi le DIH, cadre juridique de référence en situation de conflit armé, n’a-t-il pas également été mobilisé dans cette affaire ? Pour y répondre, l’article met d’abord en lumière le rôle que la CIJ peut jouer dans la promotion du respect du DIH, avant d’examiner les contraintes juridictionnelles qui ont empêché l’invocation de ce régime juridique dans cette affaire. Après avoir identifié ces contraintes, il analyse comment le DIH pourrait néanmoins jouer un rôle indirect dans la procédure, notamment comme outil interprétatif. L’article soutient que, même en l’absence de compétence directe de la Cour pour en connaître, un tel recours au DIH contribuerait à en promouvoir le respect. Au-delà de cette dimension interprétative, l’article s’intéresse enfin aux mécanismes complémentaires susceptibles de soutenir la mise en œuvre du DIH et la lutte contre l’impunité en Syrie. Il conclut que, bien que la procédure engagée devant la CIJ constitue une avancée importante pour la justice internationale, elle demeure insuffisante sans une mobilisation parallèle du DIH et d’autres mesures complémentaires. Pour autant, loin de représenter une occasion définitivement manquée de renforcer le respect du DIH, cette affaire devrait plutôt être envisagée comme une étape vers une approche plus globale, où l’action contentieuse intentée devant la CIJ s’articulerait avec d’autres efforts afin de garantir une justice plus large et renforcer le respect du droit international des droits humains et du DIH en Syrie.
Given a countable group A with trivial bounded cohomology for all semi-separable coefficients and any group $\Gamma$, we prove that the bounded cohomology of certain restricted verbal wreath products $\Gamma \wr^{_W} A$ vanishes in positive degrees, for all semi-separable coefficients. Examples of such verbal wreath products include the standard restricted wreath product (extending a recent result by Monod for lamplighters groups) as well as verbal wreath products arising from n-solvable, n-nilpotent and k-Burnside ($k = 2,3,4,6$) verbal products. Moreover, we prove that the stable commutator length of any verbal wreath product $\Gamma \wr^{_W} A$ vanishes. As an application, we show that every group of type $F_p$ isometrically embeds into a group of type $F_p$ with vanishing bounded cohomology in degree $n\geq 1$ for all semi-separable coefficients.
This article proposes a framework for considering recorded sounds in electroacoustic music, focusing specifically on their physical connection to real-world sources. This is achieved through an intermedial model, whereby ontological discussions from the field of photography are transposed to the sonic arts. It analyses the concepts of indexicality and the trace – fundamental to the writings of photographic theorists including Bazin, Barthes and Gunning – and applies them to the medium of recorded sound. The discussion establishes a means of considering source sounds primarily based on physical causality rather than resemblance and metaphor. By framing the recording process as a direct indexical link to the source equivalent to the photographic image, the article offers a novel way to analyse and compose abstract electroacoustic works that retain a tangible connection to reality.
Can economic crises erode ethno-racial solidarity? This study examines linked fate, the belief that one’s life is intertwined with others, during the 2008 recession. Using 2004–2016 American National Election Studies data, we apply time-series analysis to test the racial utility heuristic among Black and Latino respondents. Linked fate declines after the recession, continuing through 2012, but the effect is statistically significant only for Black respondents. Financial hardship shows no direct association with linked fate, yet group trends vary by income and education. These findings suggest that while linked fate may be resilient to individual economic strain, macroeconomic downturns can selectively weaken group-based political cohesion.
The present article focuses on five recent Japanese-language research monographs on the history of the Chinese Communist Party (CCP) and the People’s Republic of China (PRC), authored respectively by Eda Kenji, Mishina Hidenori, Zhou Jun, Takahashi Nobuo, and Suzuki Takashi. The books cover a wide span, reaching from the history of the early years of the CCP through the Communist-Nationalist civil war era, the early years after the founding of the People’s Republic, the implementation of the Great Leap Forward policy, the Cultural Revolution, and until the contemporary Xi Jinping regime. Based on a joint review workshop held at the Institute for Research in the Humanities at Kyoto University in 2025, the article discusses the contributions of the five books and the perspectives of their respective reviewers.
Se presentan evidencias de la cadena operativa alfarera de la fase Cabuza del valle de Azapa, norte de Chile, detallando materias primas con microscopía óptica (n = 130) y mineralogía (n = 40), para ahondar en su relación con el estado altiplánico de Tiwanaku. Las técnicas de manufactura y el uso de las vasijas, junto con los grupos mineralógicos modelados, han sido contrastados con las categorías estilísticas establecidas, redefiniendo nuevos grupos estilístico-tecnológicos. Dos grupos mineralógicos agrupan los estilos Cabuza (Min1) y Tiwanaku (Min2), congregándose en tres clústeres según los modelos bayesianos: C1 y C3 (Min1) y C2 (Min2). Min1 tiene una mezcla natural de componentes máficos presentes en las variantes Cabuza C1-Cab A1 y C3-Cab A1, como también en el estilo local Maytas (C1-Maytas) y en cerámicas Tiwanaku locales de C3 con pastas grisáceas (Munsell 7,5YR 2,5/2 – 4/3) y con decoración Cabuza (C3-Tiw/Cab); además de cerámicas Tiwanaku B de cocción oxidante (C3-Tiw/oxi). Este conjunto sería local y diferente a Min2 y C2 que agrupan las variantes Tiwanaku con pasta gris (C2-Tiw/gris) y con cocción oxidante (C2-Tiw/oxi), además de cerámicas Tumilaca sin uso (C2-Tumilaca). La discusión de estas categorías estilístico-tecnológicas sugiere que las prácticas alfareras de la fase Cabuza son post-colapso de Tiwanaku.
Canada has had a meaningful impact on international law through its participation in the development of the case law of the International Court of Justice (ICJ). Several arbitral awards involving Canada, even before the establishment of the ICJ’s predecessor, the Permanent Court of International Justice, were instrumental in shaping subsequent jurisprudence in different areas of international law. Canada’s participation in proceedings before the Court, as a party and intervener in contentious cases and as a participant in advisory proceedings, has been rich in legal arguments on fundamental issues, such as the functioning of the United Nations, the ICJ’s jurisdiction, the law of the sea, environmental law, and the law of state responsibility. Perhaps even more significantly, the activities and statements made by Canada’s courts, executive, and legislature are frequently relied-upon examples of state practice in pleadings before the Court. Finally, although Canada has had only one elected judge on the bench of the ICJ, Canadian jurists have frequently served as judges ad hoc and as counsel and advocates for states.