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This study investigates the relationship between trauma and caregiver depression in Haiti, a country burdened by ongoing political unrest, natural disasters, and economic hardship. A preponderance of evidence shows the substantial impact of caregiver mental health on child development and intergenerational vulnerability. This cross-sectional analysis examined data from the Grandi Byen randomized controlled trial, including 480 caregiver-infant dyads in Cap-Haitien. Depression risk was assessed using the Zanmi Lasante Depression Symptom Inventory (ZLDSI), and trauma exposure was measured with a survey adapted from the Life Events Checklist for DSM-5 (LEC-5). Negative binomial and ordinal logistic regression models assessed the relationship between caregiver trauma and depression, adjusting for demographic, socioeconomic, and environmental conditions. The analysis revealed that trauma exposure was significantly associated with higher odds of depression risk (OR = 1.09; 95% CI: 1.001, 1.193). Household composition was identified as a protective factor for depression (OR = 0.81; 95% CI: 0.664, 0.910). Trauma exposure was significantly associated with caregiver depression in Haiti, likely exacerbating the mental health challenges faced by caregivers in the context of political, economic and environmental stressors. Given the limited mental health data available in Haiti, this study provides essential insights into the trauma and challenges Haitians experience amidst ongoing crises.
The emergence of complex cropping systems involving dual land use raises new questions regarding plant growth under intermittent shade conditions. Recent meta-analyses have investigated the dose–response relationships of several plant traits to light availability, highlighting the strong interest in understanding plant responses to light temporal variation. However, these studies also reveal significant gaps in our knowledge, particularly concerning plant responses to low-light conditions and the determinants of crop yield under shade. In this context, physiological mechanisms related to photosynthesis, growth, reproduction and, more broadly, carbon allocation appear to play a central role. This article emphasizes the major implications of carbon allocation, storage and use under prolonged and fluctuating shaded conditions for crop production.
Nebraska has significant acreage under a continuous corn production system each year, in which managing volunteer corn remains a persistent challenge for growers. A new premix of glufosinate/quizalofop (Zalo®) was recently registered for weed control in glufosinate-resistant canola, cotton, and soybean. The objectives of this study were to (1) compare glufosinate/quizalofop (Zalo®) with quizalofop (Assure® II) applied at V3 or V6 growth stages for control of glufosinate/glyphosate-resistant volunteer corn in corn resistant to aryloxyphenoxypropionates (Enlist® corn), and (2) evaluate interactions with 2,4-D and their effects on volunteer corn density, biomass, and corn yield. Field experiments were conducted in 2023 and 2024 near Clay Center, NE (three site-years) and in 2024 near Rosemount, MN (one site-year). Glufosinate/quizalofop applied at 706 or 948 g ai ha–1 provided 98% to 99% control of volunteer corn, as well as reductions in density and biomass 28 days after application (DAA), regardless of volunteer corn planting density and corn growth stage at herbicide application, and these outcomes were comparable to quizalofop applied at 65 or 86 g ai ha–1. When the lower rate of glufosinate/quizalofop (706 g ai ha–1) was mixed with 2,4-D (1,064 g ae ha–1), volunteer corn control ranged from 84% to 92% at 14 DAA across two site-years. Volunteer corn control improved to ≥ 96% by 28 DAA or when the higher rate of glufosinate/quizalofop (948 g ai ha–1) was mixed with 2,4-D 14 DAA. Enlist corn yield increased in the plots sprayed with herbicides compared with the nontreated control, with no difference among herbicide programs and it was comparable to the weed-free treatment. The results of this study indicate that glufosinate/quizalofop could provide an effective postemergence herbicide option for managing glufosinate/glyphosate-resistant volunteer corn, pending registration for use in Enlist® corn.
North Carolina farmers have extensively relied on atrazine for effective weed control in corn, particularly for Palmer amaranth. In 2016, a grower from Washington County, NC, reported a control failure of Palmer amaranth in a corn field treated with atrazine. Greenhouse studies were conducted with the objectives to confirm if the Washington County Palmer amaranth population was resistant to atrazine and to determine other effective postemergence herbicides. Two atrazine-susceptible Palmer amaranth populations collected from Edgecombe and Johnston County were used for comparison. Greenhouse response assays confirmed the Washington County population is resistant, with a lethal dose causing 50% mortality (LD50) of 1,253 g ai ha-1. This population was 7- and 9-fold less susceptible to atrazine compared with the Edgecombe (LD50: 208 g ai ha-1) and Johnston County (LD50: 155 g ai ha-1) populations, respectively. Additionally, the LD80 (lethal dose causing 80% mortality) of the Washington County population (12,107 ga ai ha-1) was more than five times greater than the maximum labeled rate for atrazine. A subsequent herbicide screen that utilized field labeled rates suggested that 2,4-D, dicamba, fomesafen, glufosinate, and mesotrione provide at least 79% or greater control of the Washington County population. The Washington County population was not effectively controlled by thifensulfuron or glyphosate, both of which have widespread resistance documented throughout North Carolina. The results of these experiments provide evidence that the Washington County population is resistant to atrazine, glyphosate, and thifensulfuron, and effective herbicides to manage this population were confirmed.
The eastern Jebilet successions record major palaeogeographic and tectono-sedimentary changes during the Variscan orogeny, but the chronology of key events remains incompletely constrained because of the many allochthonous carbonate units and the strong deformation. Here, three autochthonous outcrops and six allochthonous units of the eastern Jebilet nappe were sampled for microfossils, with emphasis on Viséan foraminifers recovered from washed residues and thin sections. Forty-five out of 155 samples yielded diagnostic assemblages which allowed a more precise biostratigraphy. The base of the Kharrouba Formation is dated for the first time as at least middle Viséan Cf5, and the middle and upper parts are Asbian Cf6γ1-2. An Upper Devonian age for the pre-Viséan deposits of eastern Jebilet is indicated by reworked Famennian conodonts collected from the base of the Kharrouba Formation. Most allochthonous units contain upper Viséan foraminiferal associations. These new data provide improved chronological constraints on (i) the Viséan transgression in eastern Jebilet, (ii) the emplacement of the eastern Jebilet nappe, (iii) the provenance of the nappe units and (iiii) the regional correlations between the Meseta and adjacent domains. Our results confirm a marine connection with the Palaeotethys Ocean, suggesting the proximity of the Meseta to Gondwana.
Echinococcosis is a global zoonotic infection caused by larval stages of Echinococcus species. In sub-Saharan Africa, cystic echinococcosis caused by Echinococcus granulosus is prevalent, but comprehensive data are limited. This study investigates the role of lions (Panthera leo) as potential hosts for Echinococcus species, particularly E. equinus and E. felidis, in Greater Kruger National Park, South Africa. Four lion intestinal samples were macroscopically examined. High burdens of Echinococcus spp. worms were observed in 2 lions, a low-level infestation was detected in 1 lion and no parasites were identified in the fourth lion due to advanced decomposition of the sample. PCR analysis identified E. equinus in 2 samples and E. felidis in 1. Morphological and scanning electron microscopy studies provided detailed descriptions of the adult form, confirming the presence of these parasites. The findings underscore the importance of lions in the sylvatic cycle of echinococcosis and suggest potential implications for the epidemiology of the disease in African wildlife ecosystems. This study contributes to the understanding of the transmission dynamics of Echinococcus species in southern Africa.
Since the 1980s, many African countries began to adopt competition laws alongside structural adjustment and trade liberalization measures, selectively borrowing from existing EU and U.S. regimes. Today, in response to global consolidation in digital markets, African governments are embracing sectoral regulatory schemes that have pro-competitive aims but go beyond traditional competition law. The structure and goals of the EU’s Digital Markets Act (DMA) are now being reflected in national and regional African frameworks such as the AfCFTA Competition Protocol, South Africa’s Online Intermediation Platforms Market Inquiry, and Kenya’s Competition Amendment Bill. The proliferation of these pro-competitive regimes in the African region even in the face of emerging trade pressure leads to two principal lessons. First, there seems to be an important alignment of interests between the EU and African jurisdictions vis-à-vis tech (U.S.) giants. Second, despite the many limits of African competition authorities’ enforcement capabilities, pro-competitive regimes illustrate a hopeful appetite for an enforcement approach to tech markets that is not antithetic to traditional economic development rationales and yet leaves space for local and regional African values. Even with a regulatory regime formally on the books, however, adding substance to it requires significant implementation work.
As biodesigners increasingly engage with designing for nature, collaboration with field-based scientists becomes necessary. While collaborations in the laboratory have been widely examined, the formation phase of design–science collaboration remains mostly underexplored. Domains such as marine zoology produce knowledge primarily in situ, under environmental constraints that limit designers’ access to the research site and prevent the kind of embedded, informal knowledge-sharing that often grounds laboratory collaboration. As a case study, an exploratory diagnostic workshop with nine early-career marine zoologists examined these conditions. Structured activities surfaced cognitive capacities, work ecologies, role expectations and structural constraints shaping collaboration. Scientists showed strong integrative thinking but framed design mainly as technical service, while mutual stereotyping obscured shared capacities. The study provides empirical insight into rarely examined field-based research ecologies and suggests that a structured diagnostic workshop during team formation can reveal methodological and epistemic compatibility factors that informal conversations often leave implicit, positioning this phase as a critical site of interdisciplinary practice.
Abelisaurid dinosaurs display a remarkable diversity in cranial ornamentation, which includes several features such as rugosities, pits and grooves on the rostrum and orbital regions, midline knobs, and paired plus sculptured structures across the skull roof. To investigate macroevolutionary patterns that underlie this diversity, we tested the “species recognition” hypothesis using phylogenetic comparative methods. Our results indicate directional and ordered evolutionary patterns in cranial ornamentation that are more consistent with expectations of sexual selection than with the stochastic patterns predicted under the species recognition hypothesis. Moreover, sympatric species exhibited highly divergent ornamentation, and the degree of surface texturing and the development of certain structures (e.g., knobs) increased through ontogeny. These findings suggest that cranial ornamentation in Abelisaurids was influenced by mechanisms of sexual selection, sexual dimorphism, or mutual selection. Evolutionary modeling combined with evidence from the fossil record and phylogenetic correlation analysis reveals that the ornamentation of the rostrum and orbital regions was evolutionarily coupled and became canalized during the Early Cretaceous. In contrast, phylogenetic correlation analyses demonstrated that skull roof ornaments and rostral and orbital ornaments evolved decoupled. Neither discrete ornament traits nor the accumulation of traits over time showed significant associations with body size, indicating that ornament diversification in Abelisauridae was not constrained by allometric trends. During the Late Cretaceous, after refined ecological specialization, the subclades Carnotaurini and Majungasaurinae underwent further elaboration, acquiring features such as a prominent midline knobs, paired structures, and reinforced occipital and cervical regions. These derived morphologies may have facilitated more complex sociosexual behaviors.
This study systematically addresses the design and aerodynamic optimization of tail configurations for bio-inspired flapping-wing robot. Based on a flapping-wing robot prototype, a theoretical model linking tail-size parameters to the pitch static stability margin was established. Six types of tail configurations — arc-shaped tail, triangular-shaped tail, swallow-shaped tail, webbed tail, T-shaped tail, and V-shaped tail — comprising 17 parametrically varied specimens were designed and fabricated. Through a high-precision decoupled wind-tunnel test platform (free stream velocity: 10 m/s, flapping frequency: 2.5 Hz), the three-axis aerodynamic moments (pitch, yaw, roll) under various actuation states were quantitatively measured. The influence of key geometric parameters such as characteristic width, opening angle, and control-surface area on handling and stability was thoroughly investigated. Experimental results show that the T-shaped tail (#53) performs best in pitch control moment and lateral-directional stability margin, with a peak pitch moment of 0.185 N·m — approximately 42 % higher than the baseline configuration — demonstrating the most outstanding overall performance. The V-shaped tail (#62) exhibits excellent lateral-directional control capability under differential actuation, achieving a roll moment of up to 0.106 N·m, albeit with pronounced control coupling effects. This research provides reliable experimental evidence and a theoretical reference for the configuration selection and parameter optimization of tails in flapping-wing robot, offering significant engineering guidance for enhancing flight quality and control effectiveness. In addition, this paper establishes a theoretical framework for preliminary tail size design based on pitch static stability and proposes a parametric design method for multi-configuration tails for flapping-wing robot. The research results not only provide a theoretical basis for tail parameter selection but also offer experimental references for tail configuration optimization and subsequent control-oriented system design.
Anoplocephalidae (Cestoda: Cyclophyllidea) is a diverse family, with the subfamily Anoplocephalinae comprising 59 genera that primarily parasitize the digestive tract of rodents and birds. Monoecocestus threlkeldi was originally described from the northern vizcacha, Lagidium peruanum, in Junin, Peru, and subsequently reported in cricetids (Holochilus spp.) in Argentina and Bolivia. In the present study, we describe a new species of the genus Monoecocestus parasitizing the southern vizcacha, Lagidium viscacia, based on specimens collected in Puno, Peru, at an elevation of 3932 m a. s. l. A total of 45 specimens of the new species were obtained and processed for morphological and molecular analysis. For molecular analysis, DNA sequences of three markers were generated: the nuclear 18S, 28S, ITS, and mitochondrial cox1. The molecular data were compared with sequences available in GenBank, confirming its inclusion in the genus Monoecocestus. Morphologically, the new species is similar to M. threlkeldi, but it can be distinguished by its smaller body size, scolex, cirrus pouch, and number of proglottides. The description of the new species Monoecocestus viscaciae improves our understanding of the diversity of cestodes in high-altitude Andean ecosystems and provides new insights into host specificity within the genus Lagidium.
We consider a fluid filament on a solid substrate, exposed to localised perturbations that modify its material properties, particularly its viscosity. The considered model geometry and material parameters are motivated by an experimental set-up involving metal filaments subjected to laser heating, which liquefies them, leading to fluid flow while the temperature is above the melting point. The localised perturbations are created by adding disjoint metal pillars, which, due to the effect of ‘thermal crowding’ – meaning increased energy absorption due to the additional deposited metal – modify the local filament properties. Depending on the pillars’ positioning, one could consider them either as ‘thermal scissors’ (splitting the filament at the pillar location into segments) or as the source of the filament’s edge melting, leading to retraction and break-up. A precise understanding of the mechanism underlying the filament’s break-up, supported by efficient simulations, enables rationalising the dynamics and final pattern formation, as well as controlling the size and positioning of the resulting metal particles. In particular, we identify numerically a bifurcation structure in which the positioning and number of pillars lead to a dramatic transition in the final outcome. While we focus on a rather specific set-up, we expect similar mechanisms to be relevant to other systems in which material parameters could be locally modified by externally imposed perturbations.
Building on Roger Cotterrell’s call to theorise the law of trusts in relation to trust as an all-pervasive sociopolitical phenomenon, we explore the interplay between these two concepts of trust in relation to the rise of neoliberalism. Here, we centre how the ability of offshore trusts to evade tax/regulatory obligations compromises the ability of sovereign states to build institutions that nurture trust. Historicising this dynamic, we turn to how the rise of a post-imperial world of sovereign states in the context of decolonisation and the Cold War prompted elite interest in transnational legal innovations – especially trusts – that could avoid state-led redistribution efforts. Empowered by various crises, such innovations became central to neoliberal globalisation and its erosion of trust in the sovereign state. Focus on these material dynamics provides a new lens for conceptualising the failure of human rights and anti-corruption projects whose state-centric outlook detracts attention from broader transnational forces.
Community engagement is essential to research. Community Advisory Boards (CABs) are frequently consulted to inform recruitment and engagement strategies. In our experience, a gap emerged between CAB recommendations and implementation, largely due to limitations in research infrastructure, funding, and team capacity. Researchers may underappreciate why providing contextual details about studies that relate to resources or constraints, can lead to tailored recommendations. In response, our institutional CAB now incorporates researcher input before and after consultations to clarify programmatic and institutional limitations. This ongoing, bidirectional dialogue supports more pragmatic, tailored recommendations that better align with research team capacity while advancing shared goals.
For most of American history, the American state has been an active agent of racial oppression. As the country democratized, it retained structures and practices of racial authoritarianism and coercion. But in the late nineteenth and mid-twentieth centuries, the United States underwent waves of racial democratization. For a brief while during those periods, the American state transformed itself, on balance, into an agent of racial equality. We explain the reasons for this turn and present a theoretical scheme to explain the transformation of the state’s role in American democratization. We show that the construction of a “civil rights state,” a distinctive historical alignment combining national standard-setting and varieties of coercive enforcement, best accounts for these democratizing surges. We further demonstrate that both standard-setting and coercion are essential components of the civil rights state. When they converge, racial democratization is possible; when they do not, racial democratization is less likely.
Rapid molecular blood culture identification (BCID) enables earlier pathogen identification and targeted antibiotic therapy compared with traditional culture-based methods. Methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia is optimally treated with anti-staphylococcal β-lactam antibiotics; however, delays in bacterial identification frequently result in prolonged empiric anti-methicillin-resistant Staphylococcus aureus (MRSA) therapy. Data evaluating the clinical impact of early MSSA identification remain limited.
Methods:
This retrospective, single-center, quasi-experimental program evaluation included adult patients with monomicrobial MSSA bacteremia. Patients were grouped based on identification by BCID or conventional culture-based methods. Automatic Infectious Diseases consultation was performed for all patients. The primary outcome was a desirability of outcome ranking incorporating treatment success, acute kidney injury (AKI), and inpatient mortality. Secondary outcomes included time-to-optimal therapy, duration of bacteremia, treatment success, and hospital length of stay.
Results:
A total of 300 patients were included (150 per cohort). BCID use was associated with earlier MSSA identification (0.8 vs 2.1 days; P < .001) and earlier initiation of targeted β-lactam therapy (1.9 vs 3.8 days; P < .001). The probability of a more desirable outcome with BCID was 58.5% (95% CI: 52.5% to 64.3%), and more individuals achieved the most desirable outcome (62.0% vs 46.0%; P = .005). AKI occurred less frequently in the BCID group (23.5% vs 44.2%; P < .001).
Conclusions:
Incorporation of rapid BCID into an established automatic Infectious Diseases consultation program improved outcomes in MSSA bacteremia by facilitating earlier β-lactam therapy and reducing nephrotoxicity. Antimicrobial stewardship programs should prioritize rapid diagnostics to optimize MSSA management.
Let $k\ge 2$ and let X be a subset of the natural numbers that is k-automatic and not eventually periodic. We show that the following dichotomy holds: either all k-automatic subsets are definable in the expansion of Presburger arithmetic in which we adjoin the predicate X, or $(\mathbb {N},+,X)$ has the same definable sets as $(\mathbb {N},+,k^{\mathbb {N}})$.
In human-dominated landscapes, the effectiveness of ecological corridors in connecting wildlife populations depends not only on ecological but also on human factors, particularly on human–wildlife interactions and the acceptance of wildlife by landowners or managers. The Tenorio–Miravalles Biological Corridor in Costa Rica offers a unique opportunity to examine the relationship between local acceptance of the presence of the Endangered Baird’s tapir Tapirus bairdii and movement on private lands and the functionality of ecological corridor connectivity, as tapir sightings are common in the area. Using land-use analysis, we identified low-resistance, least-cost routes that highlight key habitat connectivity pathways. The corridor provides high structural connectivity for tapirs, with critical habitat fragments concentrated in the northern and southern sectors. In-depth interviews with 31 landowners and managers revealed varied levels of acceptance of the tapir’s presence, influenced by perceived costs and benefits, control, affective responses and trust in institutions. Although most respondents expressed positive emotions toward tapirs, their interactions and behaviours regarding tapir presence and movement on private land varied. These diverse responses underscore the range of human actions that can either impede or facilitate the movement of tapirs. Regardless of how well-connected habitats are structurally, ecological corridors in human-dominated landscapes ultimately depend on the management of human–wildlife interactions. A nuanced understanding of these dynamics is essential for developing connectivity and conservation strategies that align with the perspectives of landowners and managers, and promote sustainable coexistence between wildlife and people.