The mechanical feedback from the central active galactic nuclei (AGNs) can be crucial for balancing the radiative cooling of the intracluster medium (ICM) at the cluster centre. We aim to understand the relationship between the power of AGN feedback and the cooling of gas in the centres of galaxy clusters by correlating the radio properties of the brightest cluster galaxies (BCGs) with the X-ray properties of their host clusters. We used the catalogues from the first SRG/eROSITA All-Sky Survey (eRASS1) along with radio observations from the Australian SKA Pathfinder (ASKAP). In total, we identified 134 radio sources associated with BCGs of the 151 eRASS1 clusters located in the PS1, PS2, and SWAG-X ASKAP fields. Non-detections were treated as upper limits. We correlated the radio properties of the BCGs (radio luminosity, largest linear size/LLS, and BCG offset from the cluster centre) with the integrated X-ray luminosity of the host clusters. We utilised the concentration parameter, $c_{R_{500}}$, to categorise the clusters into cool cores (CCs) and non-cool cores (NCCs). By combining $c_{R_{500}}$ with the BCG offset, we assessed the dynamical states of the clusters in our sample. Furthermore, we analysed the correlation between radio mechanical power and X-ray luminosity within the CC subsample. We observe a potential positive trend between LLS and BCG offset, which may hint at an environmental influence on the morphology of central radio sources. We find a weak trend suggesting that more luminous central radio galaxies are found in clusters with higher X-ray luminosity. Additionally, there is a positive but highly scattered relationship between the mechanical luminosity of AGN jets and the X-ray cooling luminosity within the CC subsample. This finding is supported by bootstrap resampling and flux-flux analyses. The correlation observed in our CC subsample indicates that AGN feedback is ineffective in high-luminosity (high-mass) clusters. At a cooling luminosity of $L_{\mathrm{X},\,r} \lt \mathrm{R}_{\mathrm{cool}}\approx 5.50\times10^{43}\,\mathrm{erg\,s^{-1}}$, on average, AGN feedback appears to contribute only about $13\%-22\%$ of the energy needed to offset the radiative losses in the ICM.

Linguistic alignment that occurs during interaction has been found to be a useful language learning mechanism. Recent second language (L2) research on alignment has primarily focused on syntactic alignment in face-to-face oral interactions (Kim & Michel, 2023). This study expands the scope of L2 alignment research by examining pragmatic alignment in group mobile text-chat tasks conducted in Korean. Furthermore, it investigates how the source of alignment (i.e., prime, recast) and learner factors (i.e., L2 proficiency, prior knowledge of the target feature, mobile literacy, and Korean typing skills) influence the extent of L2 alignment and subsequent alignment-driven language learning. Over a period of six days, 87 Korean language learners were randomly distributed across either a prime, recast prime, or control condition and completed the following: a background survey, a pretest, four alignment tasks, two posttests, and a Korean proficiency test. During the alignment text-chat tasks, learners used the KakaoTalk mobile text-chat application to interact with two native Korean speakers who elicited Korean honorific request-making expressions in specified scenarios. The prime group received model examples prior to their production, while the recast prime group received recasts in response to non-target-like production. The learners’ use of honorific expressions was evaluated for both suppliance and accuracy across the pretests, alignment task performance, and posttests. The results revealed evidence of pragmatic alignment, with the recast prime condition demonstrating greater effects on honorific request head acts compared to the prime condition. Additionally, prior knowledge of request-making strategies facilitated L2 alignment. The implications of pragmalinguistic development through alignment-driven text-chat tasks are further discussed.

On March 28, 2025, a 7.7-magnitude earthquake struck the Sagaing region of Myanmar, resulting in 3,816 deaths and 5,104 injured, with Mandalay Region sustaining the most severe damage. Singapore Emergency Medical Team (SGEMT), verified by the World Health Organization (WHO) in 2024 as a Type-1 fixed Emergency Medical Team (EMT), was deployed in response. This mixed-methods study reports on the patient case mix and operational challenges encountered during the deployment. Data were derived from daily situation reports, clinical health records consistent with the WHO minimum data set (MDS), post-deployment review proceedings, and unstructured interviews with administrative, clinical, and logistics leads.

Deployment was delayed by diplomatic complexities and logistical challenges in freight transport. Clinical operations commenced on April 8, 2025 at Bahtoo Stadium, Mandalay, where SGEMT managed 1,803 patients over eight days. Quantitatively, 21.6% presented with direct earthquake-related injuries, 7.9% with conditions indirectly related to displacement, and 70.5% with chronic or unrelated conditions, reflecting patterns observed in other post-earthquake responses. Acute respiratory infections were the predominant infectious disease. Most patients were female, underscoring the importance of gender-sensitive approaches. The integration of a physiotherapist in a Type-1 facility, beyond WHO EMT minimum standards, enhanced clinical efficacy and rehabilitative capacity.

Qualitatively, thematic analysis guided by the 4Cs of disaster partnering –coordination, cooperation, communication, and collaboration – revealed critical enablers and constraints within the Association of Southeast Asian Nations (ASEAN) humanitarian framework. Findings highlight the need to reinforce regional coordination mechanisms to strengthen future disaster response in complex geopolitical situations.

While a postwar consensus largely upheld the legitimacy of the administrative state, the past two decades have witnessed a surge of critiques not seen since the 1930s. This review essay traces the evolution of these attacks from libertarian legal scholars decrying the administrative government’s alleged constitutional violations to lesser-known populist conservative figures like John Marini and Ned Ryun who frame the same developments as a subversive plot against the executive branch. Contrasted with them are defenders of the regulatory state like William Novak, who argue both for the historical precedent of state intervention as well as for its democratic legitimacy. The essay closes with a review of liberal concerns about the administrative state—exemplified by Alan Brinkley’s critique of the New Deal—and considers how defenders and critics might be speaking past one another. The debate reveals deeper fractures in American political thought and potentially new avenues for research into the politics of the administrative state in the latter half of the twentieth century.

Orientia tsutsugamushi, the causative agent of scrub typhus, is endemic to the Asia–Pacific region. In South Korea, the Boryong strain is considered dominant; however, nationwide phylogeographic distribution and genetic diversity based on clinical isolates remain incompletely characterized. In this study, 121 O. tsutsugamushi clinical isolates were collected from scrub typhus patients at 11 hospitals across South Korea between 2015 and 2024. Isolates were genotyped using 56-kDa gene sequencing and multilocus sequence typing (MLST) of seven housekeeping genes. Sequence analysis and phylogenetic reconstruction were performed using BLAST, PubMLST, BURST, MEGA11, DnaSP6, and R-based tools. Five 56-kDa genotypes were identified: Boryong (93.4%), Ikeda, Je-cheon, Young-worl, and Yeo-joo. MLST revealed 11 sequence types (STs), including five novel STs. While the Boryong strain and related STs were distributed nationwide, minor strains showed restricted distribution in northern regions. Several isolates sharing the same 56-kDa genotype exhibited different MLST STs, indicating possible recombination or local microevolution. This study provides the first nationwide MLST-based characterization of O. tsutsugamushi in South Korea and demonstrates the dominance of the Boryong strain alongside localized diversity. Our findings underscore the utility of MLST for higher-resolution typing and support the need for continued molecular surveillance to inform regional epidemiology and disease management.

The measurement of sodium excretion in 24-h urine samples is the recommended method to assess dietary salt intake to monitor salt-related public health policies. Ensuring complete collection of 24-h urine samples is important for the accurate assessment of salt intake. We compare the use of the objective biomarker, recovery of para-aminobenzoic acid (PABA), to self-reported 24-h urine completeness. Data collected from 868 men and women aged 19–64 years from the England Sodium Survey 2018/2019 (part of the UK National Diet and Nutrition Survey (NDNS)) were used to compare self-reported 24-h urine completeness based on a collection duration of 23–25 h, no missed urine collections/voids and a minimum urine volume of > 0·4 L against completeness based on the urinary recovery of oral doses of PABA. Two-thirds (69 %; 561/812) of participants who adhered to the PABA protocol provided a complete 24-h urine collection. Assessed by self-report, 71 % (619/868) of participants provided a complete 24-h urine collection. Sodium excretion was (geometric mean (interquartile range)) 127 (97–170) mmol/24 h with PABA and 126 (97–169) mmol/24 h by self-report; salt intake was 7·40 (5·65–9·94) g/d and 7·38 (4·53–8·83) g/d, respectively. The proportion of participants above the UK-recommended salt intake of 6 g/d was 70 % by both PABA and self-report. This study shows that the use of self-report of 24-h urine collection completeness provides an assessment of sodium excretion and dietary salt intake with the same accuracy as when PABA recovery is used to assess completeness.

Previous studies suggest that bilinguals can quickly identify the language to which a word belongs in order to suppress a task-irrelevant language. The current study tested whether nontarget language suppression occurs at the lexical and/or semantic levels and whether the degree of processing differs across these representational levels. Spanish–Basque bilinguals classified words by language membership and animacy, and event-related potential (ERP) results demonstrated that task demands to attend to a single target language reduced frequency effects and eliminated concreteness effects for words in the nontarget language. Results support a partially selective mechanism of bilingual language control based on task demands such that words belonging to the nontarget language are only partially processed at the lexical level and are not processed at a deeper semantic level. These findings specify the locus of bilingual language control in comprehension and call for revisions to models of bilingual visual word recognition such as BIA+.

Partition regularity over algebraic structures is a topic in Ramsey theory that has been extensively researched by combinatorialists [2, 3, 5, 15]. Motivated by recent work in this area, we investigate the computability-theoretic and reverse-mathematical aspects of partition regularity over algebraic structures—an area that, to the best of our knowledge, has not been explored before. This article focuses on a 1975 theorem by Straus [25], which has played a significant role in many of the results in this field.

Recent studies showing that some outcome variables do not statistically significantly differ between real-stakes and hypothetical-stakes conditions have raised methodological challenges to experimental economics’ disciplinary norm that experimental choices should be incentivized with real stakes. I show that the hypothetical bias measures estimated in these studies do not econometrically identify the hypothetical biases that matter in most modern experiments. Specifically, traditional hypothetical bias measures are fully informative in ‘elicitation experiments’ where the researcher is uninterested in treatment effects (TEs). However, in ‘intervention experiments’ where TEs are of interest, traditional hypothetical bias measures are uninformative; real stakes matter if and only if TEs differ between stakes conditions. I demonstrate that traditional hypothetical bias measures are often misleading estimates of hypothetical bias for intervention experiments, both econometrically and through re-analyses of three recent hypothetical bias experiments. The fact that a given experimental outcome does not statistically significantly differ on average between stakes conditions does not imply that all TEs on that outcome are unaffected by hypothetical stakes. Therefore, the recent hypothetical bias literature does not justify abandoning real stakes in most modern experiments. Maintaining norms that favor completely or probabilistically providing real stakes for experimental choices is useful for ensuring externally valid TEs in experimental economics.

In 1615, a Dutch fleet under the command of Joris van Spilbergen attacked the Mexican port of Acapulco. The port was the eastern terminus of the Manila galleons, the ships that linked Asia and the Americas during the early modern period. In the face of foreign incursion, Spanish officials in Mexico proposed to secure transpacific trade by constructing the Fort of San Diego to protect Acapulco. To build and later repair the fort, they mobilized thousands of Indigenous men through the repartimiento (rotational forced labour system) from what is now the Mexican state of Guerrero. Using the port’s accounting records, this article argues that the novelty of transpacific empire profoundly affected the social and economic lives of Mexico’s coastal and hinterland Indigenous peoples. However, the global histories of the Manila galleons and of early modern Asia–Latin American connections have overlooked the relationship between Spanish Pacific expansion and Indigenous labour in the Americas. Placing the fort’s Indigenous builders at the centre reveals not only the violent outcomes of imperial anxiety, but also how Indigenous people adapted to the advent of transpacific empire.

Plastic pollution represents far more than an environmental crisis—it serves as the gateway to a global meta-crisis encompassing climate change, hyper-consumption, biodiversity loss, and profound threats to human health. This letter examines plastic’s role as both catalyst and symptom of unsustainable global systems, arguing that addressing the plastic crisis provides a roadmap for broader systemic transformation.

Since mass production began in the 1950s, humanity has produced over 10 billion tonnes of plastic, with annual waste now reaching 400 million metric tonnes. Production is forecast to triple within 25 years, consuming one-fifth of the global carbon budget, with 90% of emissions occurring during production.

Plastics now permeate the human body. Over 16,000 chemicals are potentially present in plastics, with only 6% globally regulated. Recent research estimates 13% of cardiovascular deaths in individuals aged 55–64 are attributable to phthalates, while microplastics accelerate cancer development.

Solutions require comprehensive legislative frameworks creating financial risk and accountability. The Health Scientists’ Global Plastics Treaty, produced by the Plastic Health Council, proposes a roadmap to change, with measures such as a 70% reduction in virgin plastic production by 2040 and elimination of chemicals of concern. Ultimately, the plastic crisis offers humanity a tangible challenge that could catalyse essential systemic change toward regenerative systems working within planetary boundaries.

Oral administration of omega-3 polyunsaturated fatty acids (PUFAs) to rodents and humans is associated with an increase in gut bacteria that are predicted to synthesise short-chain fatty acids (SCFAs). We tested the hypothesis that physiological levels of omega-3 PUFAs in the distal intestinal lumen (1–50 μg/mL) are associated with increased SCFA synthesis in an in vitro fermentation model using faecal slurry from 10 healthy participants (mean age 30 years), with and without exogenous dietary fibres. SCFAs were measured by gas chromatography-flame ionisation detection (n = 10), and changes in bacterial composition were analysed by shotgun metagenomic sequencing (n = 6). In the presence of omega-3 PUFAs, there was a mean 9.3% (no inulin; P = 0.03) and 19.3% (+ 0.01 mg/mL inulin; P = 0.01) increase in total SCFA concentration at 24 h compared with paired control fermentations. Omega-3 PUFAs had a limited effect on the fermentation model microbiome in the absence of inulin. However, omega-3 PUFAs (50 μg/mL) were associated with increased abundance of Bifidobacteriaceae compared with paired control fermentations, if inulin (0.01 mg/mL) was present. Prebiotic activity of omega-3 PUFAs drives SCFA synthesis in an in vitro colonic fermentation model and is augmented by the soluble fibre inulin.

Preventing human-caused extinctions is a foundational aim of conservation. However, in addition to causing extinctions, humans have moved numerous species to new areas. A considerable percentage of these are threatened in their native ranges. Broadening our conservation ethos to include introduced species is contentious and requires critical thinking in empirical and normative dimensions to negotiate between conflicting conservation goals. Here, we present a series of questions to inspire critical thinking in the negotiation of these conflicts. Empirically, we suggest that conservationists should consider whether the effects of introduced species are due to their non-nativeness per se or are simply a consequence of the organism having a metabolism and taking up space. Importantly, this requires proper scientific comparison to the effects of similar native organisms – otherwise many claims of ‘harm’ are unfalsifiable and could be used to justify the eradication of any organism. We further propose questions to help conservationists sort facts from normative values, which often wear empirical clothes. Through empirical rigor, value transparency and critical justification of these values, we believe that twenty- first century conservation can become a future-facing and pluralistic discipline with a heightened ability to prevent extinctions in an increasingly unpredictable and novel biosphere.