In this paper, we study the existence of travelling wave solutions and the spreading speed for the solutions of an age-structured epidemic model with nonlocal diffusion. Our proofs make use of the comparison principles both to construct suitable sub/super-solutions and to prove the regularity of travelling wave solutions.

We study the Cauchy problem on the real line for the nonlocal Fisher-KPP equation in one spatial dimension,

\begin{equation*} u_t = D u_{xx} + u(1-\phi *u), \end{equation*}

$\phi *u$

$\phi (y) \equiv H\left (\frac{1}{4}-y^2\right )$

$u=1$

$D$

$\Delta _1 \approx 0.00297$

$D \ll 1$

$O(1)$

$u=O(1)$

$u$

$D \to 0^+$

$D \geq \Delta _1$

$2 \sqrt{D}$

$0 \lt D \lt \Delta _1$

$u=0$

$D$

This article offers an advanced and novel investigation into the intricate propagation dynamics of the Belousov–Zhabotinsky system with non-local delayed interaction, which exhibits dynamical transition structure from bistable to monostable. We first solved the enduring open problem concerning the existence, uniqueness and the speed sign of the bistable travelling waves. In the monostable case, we developed and derived new results for the minimal wave speed selection, which, as an application, further improved the existing investigations on pushed and pulled wavefronts. Our results can provide new estimate to the minimal speed as well as to the determinacy of the transition parameters. Moreover, these results can be directly applied to standard localised models and delayed reaction diffusion models by choosing appropriate kernel functions.

This work describes a hyperbolic model for cell-cell repulsion with population dynamics. We consider the pressure produced by a population of cells to describe their motion. We assume that cells try to avoid crowded areas and prefer locally empty spaces far away from the carrying capacity. Here, our main goal is to prove the existence of travelling waves with continuous profiles. This article complements our previous results about sharp travelling waves. We conclude the paper with numerical simulations of the PDE problem, illustrating such a result. An application to wound healing also illustrates the importance of travelling waves with a continuous and discontinuous profile.

This paper is concerned with the development and analysis of a mathematical model that is motivated by interstitial hydrodynamics and tissue deformation mechanics (poro-elasto-hydrodynamics) within an in-vitro solid tumour. The classical mixture theory is adopted for mass and momentum balance equations for a two-phase system. A main contribution of this study is we treat the physiological transport parameter (i.e., hydraulic resistivity) as anisotropic and heterogeneous, thus the governing system is strongly coupled and non-linear. We derived a weak formulation and then formulated the equivalent fixed-point problem. This enabled us to use the Galerkin method, and the classical results on monotone operators combined with the well-known Schauder and Banach fixed-point theorems to prove the existence and uniqueness of results.

We study the asymptotic behaviour of the least energy solutions to the following class of nonlocal Neumann problems:

$$ \begin{align*} \begin{cases} { d(-\Delta)^{s}u+ u= \vert u\vert^{p-1}u } & \text{in } \Omega, \\ {u>0} & \text{in } \Omega, \\ { \mathcal{N}_{s}u=0 } & \text{in } \mathbb{R}^{n}\setminus \overline{\Omega}, \end{cases} \end{align*} $$

where $\Omega \subset \mathbb {R}^{n}$ is a bounded domain of class $C^{1,1}$, $1<p<({n+s})/({n-s}),\,n>\max \{1, 2s \}, 0<s<1, d>0$ and $\mathcal {N}_{s}u$ is the nonlocal Neumann derivative. We show that for small $d,$ the least energy solutions $u_d$ of the above problem achieve an $L^{\infty }$-bound independent of $d.$ Using this together with suitable $L^{r}$-estimates on $u_d,$ we show that the least energy solution $u_d$ achieves a maximum on the boundary of $\Omega $ for d sufficiently small.

We consider a class of nonhomogeneous elliptic equations in the half-space with critical singular boundary potentials and nonlinear fractional derivative terms. The forcing terms are considered on the boundary and can be taken as singular measure. Employing a functional setting and approach based on localization-in-frequency and Littlewood–Paley decomposition, we obtain results on solvability, regularity, and symmetry of solutions.

The purpose of this paper is to derive anisotropic mean curvature flow as the limit of the anisotropic Allen–Cahn equation. We rely on distributional solution concepts for both the diffuse and sharp interface models and prove convergence using relative entropy methods, which have recently proven to be a powerful tool in interface evolution problems. With the same relative entropy, we prove a weak–strong uniqueness result, which relies on the construction of gradient flow calibrations for our anisotropic energy functionals.

This paper deals with the following quasilinear chemotaxis system with consumption of chemoattractant

\[ \left\{\begin{array}{@{}ll} u_t=\Delta u^{m}-\nabla\cdot(u\nabla v),\quad & x\in \Omega,\quad t>0,\\ v_t=\Delta v-uv,\quad & x\in \Omega,\quad t>0\\ \end{array}\right. \]

$\Omega \subset \mathbb {R}^N(N=3,\,4,\,5)$

$\partial \Omega$

$m>\max \{1,\,\frac {3N-2}{2N+2}\}$

$(\bar {u}_0,\,0)$

$t\rightarrow \infty$

$\bar {u}_0=\frac {1}{|\Omega |}\int _\Omega u_0$

$m>\frac {3N-2}{2N}$

$N\geq 3$

$m>\frac {3N}{2N+2}$

$N\geq 2$

Introducing a pair-parameter matrix Mittag–Leffler function, we study the uniqueness and Hyers–Ulam stability to a new fractional nonlinear partial integro-differential equation with variable coefficients and a mixed boundary condition using Banach’s contractive principle as well as Babenko’s approach in a Banach space. These investigations have serious applications since uniqueness and stability analysis are essential topics in various research fields. The techniques used also work for different types of differential equations with initial or boundary conditions, as well as integral equations. Moreover, we present a Python code to compute approximate values of our newly established pair-parameter matrix Mittag–Leffler functions, which extend the multivariate Mittag–Leffler function. A few examples are given to show applications of the key results obtained.

We consider the problem of minimizing the $L^\infty$ norm of a function of the hessian over a class of maps, subject to a mass constraint involving the $L^\infty$ norm of a function of the gradient and the map itself. We assume zeroth and first order Dirichlet boundary data, corresponding to the “hinged” and the “clamped” cases. By employing the method of $L^p$ approximations, we establish the existence of a special $L^\infty$ minimizer, which solves a divergence PDE system with measure coefficients as parameters. This is a counterpart of the Aronsson-Euler system corresponding to this constrained variational problem. Furthermore, we establish upper and lower bounds for the eigenvalue.

In this paper, we study the singular boundary value problem

$$ \begin{align*} \begin{cases} \Delta_\infty^h u=\lambda f(x,u,Du) \quad &\mathrm{in}\; \Omega, \\ u>0\quad &\mathrm{in}\; \Omega,\\ u=0 \quad &\mathrm{on} \;\partial\Omega, \end{cases} \end{align*} $$

where $\lambda>0$ is a parameter, $h>1$ and $\Delta _\infty ^h u=|Du|^{h-3} \langle D^2uDu,Du \rangle $ is the highly degenerate and h-homogeneous operator related to the infinity Laplacian. The nonlinear term $f(x,t,p):\Omega \times (0,\infty )\times \mathbb {R}^{n}\rightarrow \mathbb {R}$ is a continuous function and may exhibit singularity at $t\rightarrow 0^{+}$. We establish the comparison principle by the double variables method for the general equation $\Delta _\infty ^h u=F(x,u,Du)$ under some conditions on the term $F(x,t,p)$. Then, we establish the existence of viscosity solutions to the singular boundary value problem in a bounded domain based on Perron’s method and the comparison principle. Finally, we obtain the existence result in the entire Euclidean space by the approximation procedure. In this procedure, we also establish the local Lipschitz continuity of the viscosity solution.

Existence of specific eternal solutions in exponential self-similar form to the following quasilinear diffusion equation with strong absorption

\[ \partial_t u=\Delta u^m-|x|^{\sigma}u^q, \]

$(t,\,x)\in (0,\,\infty )\times \mathbb {R}^N$

$m>1$

$q\in (0,\,1)$

$\sigma =\sigma _c:=2(1-q)/ (m-1)$

\[ u(t,x)={\rm e}^{-\alpha t}f(|x|\,{\rm e}^{\beta t}), \quad \alpha=\frac{2}{m-1}\beta, \]

$\beta ^*\in (0,\,\infty )$

$(u_A)_{A>0}$

$(f_A)_{A>0}$

$f_A(0)=A$

$f_A'(0)=0$

$\sigma \in (0,\,\sigma _c)$

We formulate haptotaxis models of cancer invasion wherein the infiltrating cancer cells can occupy a spectrum of states in phenotype space, ranging from ‘fully mesenchymal’ to ‘fully epithelial’. The more mesenchymal cells are those that display stronger haptotaxis responses and have greater capacity to modify the extracellular matrix (ECM) through enhanced secretion of matrix-degrading enzymes (MDEs). However, as a trade-off, they have lower proliferative capacity than the more epithelial cells. The framework is multiscale in that we start with an individual-based model that tracks the dynamics of single cells, which is based on a branching random walk over a lattice representing both physical and phenotype space. We formally derive the corresponding continuum model, which takes the form of a coupled system comprising a partial integro-differential equation for the local cell population density function, a partial differential equation for the MDE concentration and an infinite-dimensional ordinary differential equation for the ECM density. Despite the intricacy of the model, we show, through formal asymptotic techniques, that for certain parameter regimes it is possible to carry out a detailed travelling wave analysis and obtain invading fronts with spatial structuring of phenotypes. Precisely, the most mesenchymal cells dominate the leading edge of the invasion wave and the most epithelial (and most proliferative) dominate the rear, representing a bulk tumour population. As such, the model recapitulates similar observations into a front to back structuring of invasion waves into leader-type and follower-type cells, witnessed in an increasing number of experimental studies over recent years.

We generalize the one-dimensional population model of Anguige & Schmeiser [1] reflecting the cell-to-cell adhesion and volume filling and classify the resulting equation into the six types. Among these types, we fix one that yields a class of advection-diffusion equations of forward-backward-forward type and prove the existence of infinitely many global-in-time weak solutions to the initial-Dirichlet boundary value problem when the maximum value of an initial population density exceeds a certain threshold. Such solutions are extracted from the method of convex integration by Müller & Šverák [12]; they exhibit fine-scale density mixtures over a finite time interval, then become smooth and identical, and decay exponentially and uniformly to zero as time approaches infinity. TE check: Please check the reference citation in abstract.

In this paper, we study the Dirichlet problem of Hessian quotient equations of the form $S_k(D^2u)/S_l(D^2u)=g(x)$ in exterior domains. For $g\equiv \mbox {const.}$, we obtain the necessary and sufficient conditions on the existence of radially symmetric solutions. For g being a perturbation of a generalized symmetric function at infinity, we obtain the existence of viscosity solutions by Perron’s method. The key technique we develop is the construction of sub- and supersolutions to deal with the non-constant right-hand side g.

In this work, we carry out an analytical and numerical investigation of travelling waves representing arced vegetation patterns on sloped terrains. These patterns are reported to appear also in ecosystems which are not water deprived; therefore, we study the hypothesis that their appearance is due to plant–soil negative feedback, namely due to biomass-(auto)toxicity interactions.

To this aim, we introduce a reaction-diffusion-advection model describing the dynamics of vegetation biomass and toxicity which includes the effect of sloped terrains on the spatial distribution of these variables. Our analytical investigation shows the absence of Turing patterns, whereas travelling waves (moving uphill in the slope direction) emerge. Investigating the corresponding dispersion relation, we provide an analytic expression for the asymptotic speed of the wave. Numerical simulations not only just confirm this analytical quantity but also reveal the impact of toxicity on the structure of the emerging travelling pattern.

Our analysis represents a further step in understanding the mechanisms behind relevant plants‘ spatial distributions observed in real life. In particular, since vegetation patterns (both stationary and transient) are known to play a crucial role in determining the underlying ecosystems’ resilience, the framework presented here allows us to better understand the emergence of such structures to a larger variety of ecological scenarios and hence improve the relative strategies to ensure the ecosystems’ resilience.

We will present the proof of existence and uniqueness of renormalized solutions to a broad family of strongly non-linear elliptic equations with lower order terms and data of low integrability. The leading part of the operator satisfies general growth conditions settling the problem in the framework of fully anisotropic and inhomogeneous Musielak–Orlicz spaces. The setting considered in this paper generalized known results in the variable exponents, anisotropic polynomial, double phase and classical Orlicz setting.

We show that the energy–momentum equations arising from inner variations whose Lagrangian satisfies a generic symmetry condition are ill-posed. This is done by proving that there exists a subclass of Lipschitz solutions that are also solutions to a differential inclusion into the orthogonal group and in particular these solutions can be nowhere $C^1$. We prove that these solutions are not stationary points if the Lagrangian $W$ is $C^1$ and strictly rank-one convex. In view of the Lipschitz regularity result of Iwaniec, Kovalev and Onninen for solution of the energy–momentum equation in dimension 2, we give a sufficient condition for the non-existence of a partial $C^1$ -regularity result even under the condition that the mappings satisfy a positive Jacobian determinant condition. Finally, we consider a number of well-known functionals studied in non-linear elasticity and geometric function theory and show that these do not satisfy this obstruction to partial regularity.

We consider a parabolic-parabolic chemotaxis system with singular chemotactic sensitivity and source functions, which is originally introduced by Short et al to model the spatio-temporal behaviour of urban criminal activities with the particular value of the chemotactic sensitivity parameter $\chi =2$. The available analytical findings for this urban crime model including $\chi =2$ are restricted either to one-dimensional setting, or to initial data and source functions with appropriate smallness, or to initial data and source functions with some radial symmetry. In the present work, our first result asserts that for any $\chi \gt 0$ the initial-boundary value problem of this urban crime model possesses a global generalised solution in the two-dimensional setting, without imposing any small or radial conditions on initial data and source functions. Our second result presents the asymptotic behaviour of such solution, under some additional assumptions on source functions.