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It is unclear whether patients with obsessive-compulsive disorder (OCD) and expert clinicians agree on the symptoms’ qualities that are essential for a diagnosis of OCD. This study examined whether OCD patients and expert clinicians agree on the essential characteristics for an OCD diagnosis. It compared the endorsement rates of various descriptive terms and assessed whether response profiles could predict group membership (patients versus expert clinicians).
Methods
Sixty-four OCD patients and 36 OCD expert clinicians answered a questionnaire on their views regarding the defining characteristics of OCD symptoms. It included a compilation of adjectives extracted from DSM-5 to describe disorders in the compulsive–impulsive spectrum. Chi-square tests compared response prevalence between groups and binary regression identified distinguishing features. The significance level was set at 0.05.
Results
All descriptors differed significantly between OCD patients and expert clinicians (p < 0.01), with clinicians consistently endorsing more items as applicable or essential. Although the logistic regression model significantly distinguished the 2 groups and showed high explanatory power (R2 = 0.7) with 99% classification accuracy, no individual descriptors were significant predictors.
Conclusions
There is a mismatch between clinician-defined diagnostic language and patients’ subjective experience of OCD, including core symptom descriptors. This gap suggests that current OCD diagnostic construct may not fully capture how patients perceive their condition, potentially limiting its validity and clinical utility. Adopting more patient-centered language could improve assessment, psychoeducation, and treatment engagement.
Volatile organic compounds (VOCs) pose risks to human health and the environment, making the development of efficient technologies to reduce their emissions a priority. Catalytic oxidation represents a simple, efficient and environmentally friendly method for eliminating VOCs. Herein, a spinel CuCo2O4/biochar/attapulgite (ATP) composite was successfully synthesized via a sol–gel method using waste walnut shell powder as both a complexing agent and a combustion promoter. The effect of the mass ratio on toluene degradation performance was systematically investigated. The results indicated that when the mass ratio of CuCo2O4/ATP to the biomass precursor was optimized to 1:4, the catalyst exhibited excellent catalytic oxidation performance for toluene degradation, achieving 99% conversion at 300°C along with high stability. The introduction of biochar induced the formation of abundant oxygen vacancies on the spinel surface and effectively suppressed the agglomeration of CuCo2O4 particles. Moreover, the rich functional groups on biochar improved toluene adsorption, favouring the subsequent catalytic oxidation. The current study offers a cost-effective strategy for VOC abatement by taking advantage of minerals and biomass.
Drawing on foundational work in the history of emotions, this article explores the significance of evangelical children’s search for salvation in postwar America. Reading midcentury denominational publications and children’s letters through an affective lens, this article asks how emotion, not merely belief, made evangelical childhoods. As evangelical communities passed down a conversion script teaching their children what to feel and how to feel it, kids found themselves caught between the horrors of the bomb, traditions that invoked religious fear, and the gathering force of therapeutic psychology that sought to cultivate feelings of well-being. While evangelical adults imagined that kids who lacked assurance of salvation were experiencing a problem of belief, I argue that children’s doubts exposed tensions inherent in the emotional script of conversion. These enduring tensions took on new significance in the age of the therapeutic, as the pursuit of inner peace emerged as a challenger to more transcendent claims of salvation as peace with God. Thus, even as the children of the 1950s and 1960s tried their best to follow a tried-and-true conversion script, their search for proper feelings recast the meaning of salvation itself and subtly aligned evangelicalism with the new therapeutic self of postwar America.
Since the 1980s opera and fashion directors have earnestly explored the potential for symbiotic relationships as a way to sustain performance institutions and showcase forward-thinking approaches to operatic works, as evidenced by collaborations between the creative directors of Missoni, Versace, Fendi and Armani with La Scala, the Metropolitan Opera and the Royal Opera House. In addition, fashion companies such as Dolce&Gabbana have found inspiration from opera’s long and celebrated histories within Italy, using operatic works as a platform for haute couture runway design.
This article studies three projects from Maison Valentino which are among the most recent fashionable forays into the genre of opera. In addition to collaborating on the 2016 production of La traviata with the Teatro dell’Opera di Roma, Valentino highlighted operatic heroines on the runway in 2014, and in 2018 created a collection inspired by Maria Callas, who inspired a number of repertorial revivals in the twentieth century. Valentino’s sartorial re-imaginings of nineteenth-century operatic culture on the stage and runway – achieved in both instances through incarnations of Callas – have sought to position Italian operatic history as a practical aspect of contemporary material culture. By showcasing the economic, political and social ramifications of Valentino’s collaborative efforts, I show how the company’s reformulations of operatic materials have impacted both conventional and unconventional structures of contemporary performance.
How and why is comparative law and society imperative to legal education? In the 21st century, legal education displays a paradox: despite the rise of Asia economically, socially and politically, the study of comparative law rarely includes Asian laws outside of law schools in Asia. In this article, I contribute to the debate over legal education by arguing for the imperative of comparative law and society, and its benefits for law students. I examine how law schools commit practically to comparative law and society by hiring scholars with relevant expertise and offering such subjects. I illustrate this commitment with a case study of Asian legal studies in Australia over the past seven decades (1960s-2020s). I find that Asian legal studies remains concentrated at a handful of law schools, resulting in a problem I describe as the ‘Asian Century gap’ in legal education. Closing this gap requires a renewed commitment to the study of comparative law and society as Asian legal studies through hiring choices and subject offerings. Such a commitment is necessary to ensure that our law students gain the benefits that an education in comparative law and society has to offer.
Standard portfolio-choice models treat cash as fungible. Using positions and transfer records for 46,016 Chinese investors, we show that brokerage cash is nonfungible and that cash-source effects refresh and decay. We label inflows from savings transfers as “cold” and trading-recycled funds as “hot” and construct a cash-temperature measure tracking these dynamics. Investors allocate colder cash to safer stocks, controlling for gains and losses, trading intensity, and rebalancing. Quasi-experimental variation from China’s 2016 IPO reform supports a causal interpretation. A preregistered experiment links cold framing to loss aversion; a model with temperature-dependent sensitivity to gains and losses rationalizes the evidence.
This paper elucidates the firm and corporation’s institutional coevolution via the firm-corporation linkage debate between legal institutionalism (LI) and world power system theory (WPS). To drive a sustainability transition, it proposes ‘regenerative characteristics’ – extending multidomain, multitemporal, and ecosystem characteristics. Employing a transdisciplinary approach, the study synthesises LI’s ‘emergentist’ and WPS’s ‘separation’ views through comparative institutional analysis (CIA). Integrating corporate actor theory with an Ostromian perspective, it extends CIA to identify position as the generative mechanism linking micro-level actions to macro-level institutions. Theoretically, law structures coevolutionary governance, joint production demands an agreement of joint responsibility, and ‘negotiated governance’ emphasises capability evolution. Rejecting shareholder primacy, policies must tie legal recognition to external responsibilities, foster education for moral judgement, and incentivise regenerative characteristics. Ultimately, negotiated governance transforms the firm-corporation linkage into a responsible constituent of the global commons.
During the COVID-19 pandemic, many governments recommended quarantine to those who had close contact with infected individuals. We conducted a large-scale retrospective survey to study the consequences of such quarantine for labor outcomes. A sizable fraction of quarantined workers experienced reductions in hours worked and earnings, not only during quarantine but also after quarantine. Even uninfected workers experienced negative labor impacts, likely capturing the pure effects of quarantine independent of the effects of COVID-19 symptoms. Non-regular workers and workers without remote work options were more negatively affected by quarantine. We estimate that the quarantine resulted in a large reduction in the aggregate hours and that the reduction is mainly due to the scarring effects.
The unsteady response of nozzles with wall friction forced by acoustic and/or entropy waves is modelled. The approach is based on the quasi-one-dimensional linearised Euler equations. The equations are cast in terms of three variables, namely the dimensionless mass, stagnation temperature and entropy fluctuations, which are invariants of the system at zero frequency and in the absence of wall friction. The resulting first-order system of differential equations is solved using the Magnus-expansion method, where the perturbation parameters are the normalised frequencies and Fanning friction factors. In this work, a measure of the flow non-isentropicity caused by wall friction is used for the first time as an expansion parameter. The solution method is applied to a converging–diverging nozzle with wall friction for both subsonic and supersonic flow cases, showing good agreement with numerical predictions. The nozzle flow with both wall friction and steady heat transfer is further explored. It is observed that the acoustic and entropy transfer functions of the nozzle strongly depend on the frequency, wall friction and heat transfer. Wall friction affects the unsteady response through changes in the mean flow and through coupling between acoustic, velocity and entropy fluctuations.
To characterize the treatment burden of generalized anxiety disorder (GAD) using real-world data on pharmacotherapy use, treatment changes, and treatment progression.
Methods
This retrospective analysis used closed claims from the Komodo Healthcare Map (2021–2024) to identify U.S. adults (≥18 years) with newly diagnosed or established GAD. Treatment patterns were assessed at the drug level.
Results
Among the 259 158 newly diagnosed and 1 018 288 established GAD patients, GAD-related pharmacotherapy use during the 12 months post-index was 76% and 98%, respectively. Treatment patterns were further analyzed in 59 275 newly diagnosed and 86 920 established GAD patients with ≥1 pharmacy claim. Among newly diagnosed patients, 55% discontinued and 28% added or switched treatments; among established patients, 16% discontinued and 55% added or switched treatments. The median time to first treatment event varied by cohort and event type: discontinuation occurred at a median of 84 days in newly diagnosed and 119 days in established patients, combination therapy at 49 and 32 days, and switching at 31 and 42 days, respectively. Of those who discontinued, 57% of newly diagnosed and 26% of established GAD patients did not resume treatment; among those who restarted, the median treatment gap was 146 and 96 days, respectively. Overall, 75% of newly diagnosed and 94% of established GAD patients who underwent treatment modification experienced at least one additional therapy change during the study.
Conclusion
This study underscores the significant unmet needs in the current treatment of GAD, evidenced by high rates of pharmacotherapy switching, discontinuation, and prolonged gaps in care.
The paper reinterprets the East India Company’s state-building effort in late eighteenth‑century Bengal by foregrounding the intertwined evolution of fiscal capacity and institutional reform. It argues that the Permanent Settlement of 1793 emerged not from a desire to follow Indian or English precedent, but from the Company’s struggle to concentrate fiscal powers. A debate on the need to obtain information on taxpayers, which delayed the reform, reveals this struggle. Repeated failures in data collection pushed the state to anchor the reform in an expanding judicial system capable of producing actionable information. The Settlement strengthened revenue flows, enabling the financing of a centrally controlled army and contributing to Britain’s wider imperial expansion. However, its long-term rigidity limited fiscal flexibility and impeded broader developmental outcomes.
We hypothesize that the public assesses U.S. Supreme Court nominees in light of the contemporaneous Court’s partisan composition. In a preregistered conjoint experiment (n = 9,895), we find that Democrats and Republicans weigh nominee partisanship more heavily when their party is losing the Court and less heavily when their party already enjoys a secure majority. Consistent with affective polarization and threat-based political psychology, however, they care just as much about partisanship when the Court is split as when the other party enjoys a strong majority – even though the new Justice would swing the Court only in the former scenario.
A positive integer N is said to be an infinitary harmonic number (IHN) if the harmonic mean of its infinitary divisors is integral. It is still an open problem whether or not there exist infinitely many IHNs. Cohen and Hagis [‘Infinitary harmonic numbers’, Bull. Aust. Math. Soc.41 (1989), 151–158] showed that there exist at most finitely many IHNs with a fixed number of I-components. We give an explicit Nielsen-type upper bound for the number of IHNs. We also consider a class of general infinitary amicable numbers and obtain the Borho-type upper bound for them.
Lexical acquisition often occurs through reading, yet little research has compared how cognates, false cognates, and noncognates are learned contextually through reading. To this end, we conducted a week-long pretest-training-posttest study with 54 adult Polish learners of English. During three sessions on consecutive days, participants read 45 short stories (170–317 words) containing 90 target keywords (30 cognates, 30 noncognates, 30 false cognates). We examined how word type, context informativeness, and number of keywords occurrences affected keyword learning. Additionally, participants were randomly assigned to a control or awareness-raising group, the latter trained to notice cross-linguistic similarities. Mixed-effects models showed learning of all word types at immediate posttest, with cognates being learned the most and false cognates the least. Higher context informativeness and more keyword occurrences improved learning for all keywords, but false cognates benefited the most from contextual clues. However, raising awareness of cross-linguistic similarity did not enhance contextual learning.
The discipline of political science lacks a systematic understanding of how scholars studying Middle East politics prepare for and navigate in-country research, even as fieldwork plays a vital role in contemporary scholarship about the region. Drawing on evidence from an original survey of scholars studying the Middle East and North Africa, we identify a training–practice misalignment wherein 38% of respondents reported having received no formal training before entering the field despite almost all respondents claiming to have conducted fieldwork. Qualitative evidence from open-ended responses reveals the frustration that many scholars experience due to their lack of formal training and subsequent dependence on informal networks and knowledge. Conflict, authoritarianism, state surveillance, and repression in public space—characteristics that increasingly are prevalent in many parts of the world—have long shaped the practice of fieldwork in the Middle East, rendering our findings significant beyond this region alone. The article discusses implications of this misalignment for this subfield and the discipline more broadly, as well as potential pathways forward.
This study investigated information retrieval of preprint records in the context of evidence synthesis work and compared 12 sources used to discover preprints. Identification of grey literature is often required or recommended in evidence synthesis guidance, and preprints are categorized as grey literature. The purpose of this work is to inform how and where to search for preprints to maximize coverage (through exploration of preprint server across aggregators and databases) while balancing search efficiency. Authors selected aggregators and databases hosting two or more preprint servers and then tested search functionality and extracted characteristics and features. Authors analyzed and compared the selected sources, tabulated the number of essential features, and created comparison tables reflecting database and aggregator features. The study protocol was registered in Open Science Framework registries. Preprint aggregators and databases differ in their content coverage, and their ability to design a comprehensive and reproducible search strategy. Limitations such as character or word limits for queries, limited advanced search operators, and missing export functionality affect the usability of aggregators for evidence synthesis searches. Ongoing updates to search interfaces and functionality and differing approaches to versioning make it challenging to study discovery of preprints across sources. The recommendations and scenarios in this article will assist searchers engaged in evidence synthesis to make informed decisions about where to search for preprints.
This article examines how racialised memes circulating on X revive scientific racism, demonstrating that hybrid formats reconfigure biological essentialisation within contemporary digital culture. Using a corpus of 68 viral items and 4 case studies, our analysis applies Shifman’s content–form–stance model, informed by cognitive psychology. We show that these memes adopt common scientific conventions while relying on visual polarisation, whereby rapid perceptual contrasts stand in for arguments. Familiar templates, reinforced by selective algorithmic amplification, create a sense of perceptual legitimacy through fast categorisation and pre-attentive processing. We also trace how these cognitive shortcuts provide the basis for a regime of racialisation tailored to digitally immersed male audiences, producing gendered behavioural stereotypes and disappearance anxieties. A further pattern is the recoding of older racial hierarchies into neutral-sounding language of competence, allowing these ideas to travel across racialist, masculinist, techno-elitist, and anti-DEI (Diversity, Equity, Inclusion) communities. In this environment, memes work as micro-infrastructures of classification that align claims to objectivity with affect and platform incentives, making inequality appear natural and necessary. We conclude that effective critique must meet these images on their own terrain, with a pedagogy of the gaze that teaches publics how to recognise and challenge persuasion in meme-driven spaces.
A key task in conducting systematic reviews is deduplicating the results from database searching. Deduplication using reference management software can be time-consuming and prone to error, while automated tools can be expensive and lack transparency. To support review teams, we evaluated eight deduplication tools: (1) The Automated Systematic Search Deduplicator (ASySD); (2) Covidence; (3) Deduklick; (4) EPPI-Reviewer; (5) PICO Portal; (6) Rayyan; (7) The Systematic Review Accelerator (SRA) Deduplicator: Focused; (8) The SRA Deduplicator: Relaxed. Five randomly selected Cochrane reviews had their searches rerun to create five gold standard sets. We compared the gold standard sets to the outputs of the eight deduplication tools and evaluated the results for: (1) unique records removed; (2) duplicate records retained; (3) time taken to deduplicate. Summed across all five reviews, the unique records removed in error ranged from 2 to 22. The three best tools were: (1) Rayyan; (2) Covidence; (3) SRA Deduplicator: Focused. The duplicate records retained in error ranged from 34 to 280, the three best tools were: (1) ASySD; (2) Rayyan; (3) EPPI-Reviewer. The time taken to deduplicate ranged from one minute to 20 hours and 34 minutes, the three fastest tools were: (1) SRA Deduplicator: Relaxed; (2) Deduklick; (3) Covidence. No tool performed so poorly that we don’t recommend using it. But, as all the tools had strengths and weaknesses, some are expensive while others require large amounts of manual checking time, we recommend review teams compare the tools across all three outcomes and choose the tool that best suits their needs.