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Pendant drops appear in many engineering applications, such as inkjet printing and optical tensiometry, and they have also been the subject of studies of droplet–particle interaction. While the hydrostatics of pendant drops has been studied extensively, the influence of external flow disturbances has received limited attention. This research aims to incorporate aerodynamic factors into the understanding of pendant drop behaviour. Employing a simplified model, an irrotational flow aligned with the drop’s axis is derived from a distribution of singularity elements within the drop. The drop’s equilibrium shape is then determined using a numerical model that couples the flow field with the Young–Laplace equation. The model’s predictions are compared to droplet images captured via high-speed shadowgraph in a vertical wind tunnel, showing good agreement with the experimentally observed shapes. Additionally, under certain flow conditions, the drop exhibits instability in the form of periodic pendulum-like motion. This instability was linked to two distinct critical drop heights, and the corresponding stability criterion was mathematically derived from the numerical model. Our theoretical and experimental findings provide the first quantitative description of the equilibrium shape and stability criterion of pendant drops under the influence of external flow.
A redescription of Cloeosiphon aspergillus is presented based on the type material and additional specimens from Madagascar, South Africa, and New Caledonia. Cloeosiphon aspergillus is characterized by its pineapple-shaped anal shield, bidentate hooks arranged in rings, and a continuous longitudinal muscle layer. Additionally, a new species, Cloeosiphon mexicanus sp. nov. is described from the southern Mexican Pacific. This new species differs from C. aspergillus by having an inconspicuous secondary tooth on posterior hooks and the absence of spherical units along the basal margin of the anal shield. Furthermore, a discussion on the synonyms of C. aspergillus is included. This study expands the taxonomic knowledge of the genus Cloeosiphon and highlights the importance of the detailed description for accurate species recognition.
Given a finite abelian group $G$ and $t\in \mathbb{N}$, there are two natural types of subsets of the Cartesian power $G^t$; namely, Cartesian powers $S^t$ where $S$ is a subset of $G$ and (cosets of) subgroups $H$ of $G^t$. A basic question is whether two such sets intersect. In this paper, we show that this decision problem is NP-complete. Furthermore, for fixed $G$ and $S$, we give a complete classification: we determine conditions for when the problem is NP-complete and show that in all other cases the problem is solvable in polynomial time. These theorems play a key role in the classification of algebraic decision problems in finitely generated rings developed in later work of the author.
Experiments have shown that ultrasound-stimulated microbubbles can translate through gel phantoms and tissues, leaving behind tunnel-like degraded regions. A computational model is used to examine the tunnelling mechanisms in a model material with well-defined properties. The high strain rates motivate the neglect of weak elasticity in favour of viscosity, which is taken to degrade above a strain threshold. The reference parameters are motivated by a 1 $\unicode{x03BC}$m diameter bubble in a polysaccharide gel tissue phantom. This is a reduced model and data are scarce, so close quantitative agreement is not expected, but tunnels matching observations do form at realistic rates, which provides validation sufficient to analyse potential mechanisms. Simulations of up to 100 acoustic cycles are used to track tunnelling over 10 bubble diameters, including a steady tunnelling phase during which tunnels extend each forcing cycle in two steps: strain degrades the tunnel front during the bubble expansion, and then the bubble is drawn further along the tunnel during its subsequent inertial collapse. Bubble collapse jetting is damaging, though it is only observed during a transient for some initial conditions. There is a threshold behaviour when the viscosity of the undamaged material changes the character of the inertial bubble oscillation. Apart from that, the tunnel growth rate is relatively insensitive to the high viscosity of the material. Higher excitation amplitudes and lower frequencies accelerate tunnelling. That acoustic radiation force, elasticity and bubble jetting are not required is a principal conclusion.
An asymptotic model for the flow of a highly viscous film coating the interior of a slippery, flexible tube is developed and studied. The model is valid for the axisymmetric flow of moderately thick films, and accounts for tube flexibility, wall damping, longitudinal tension, slip length and strength of base flow due either to gravity or airflow. In the absence of base flow, linear stability analysis shows the existence of one unstable mode; the presence of base flow allows for multiple unstable modes arising due to the Plateau–Rayleigh instability and elastic instability, with stronger base flow reducing the maximum growth rate. Numerical solutions in the absence of base flow show that slip decreases the amplitude of wall deformations and can significantly decrease the time to plug formation in weakly flexible or strongly damped tubes. For falling films, the impact of model parameters on the critical thickness required for plug formation was analysed by studying turning points in families of travelling-wave solutions; this thickness decreases with slip, flexibility and tension, while damping had a non-monotonic impact on critical thickness. In contrast to model solutions in rigid tubes, for flexible tubes the critical thickness cannot be made arbitrarily large through simply increasing the strength of the base flow. For air-driven films, both slip and flexibility increase the rate of film transport along the tube.
Dignity has been a notoriously elusive concept to philosophers. Nevertheless, in the realms of politics, law, and policymaking, appeals to dignity are frequent, and do not always align with the understandings most commonly endorsed by the philosophical literature. This paper considers how “dignity” is frequently appealed to in ethical arguments about the permissibility of abortion, and argues that the judicial decisions related to reproductive and LGBTQ+ rights over the past 30 years in the United States offer deep insights into the nature of “dignity” that philosophers and other theorists ought to pay attention to. These insights not only have profound implications for our understanding of the nature of “dignity,” but also for ethical analysis more broadly.
Gambling-related harm is a global public health concern. Suicide mortality is increased among people who experience gambling harm, and people who die by suicide often have contact with mental health treatment services in the months preceding their death.
Aims
To assess via a case–control study how gambling diagnosis predicts suicidal death and mental healthcare utilisation using linked routinely collected healthcare data.
Method
We linked the Welsh Longitudinal General Practice Dataset, Annual District Death Extract, Patient Episode Database for Wales, and Outpatient Appointments Dataset Wales using the Secure Anonymised Information Linkage (SAIL) Databank. A sample of individuals with gambling diagnosis who died by suicide and an age- and sex-matched comparator group of all-cause decedents between 1993 and 2023 were extracted. Predictors of suicidal death, including mental health diagnosis and treatment contacts, were analysed using binary logistic regression models and chi-squared tests.
Results
A matched cohort of 92 individuals diagnosed with a gambling diagnosis (mean age 61.5 years, s.d. 13.1; 71% male) who died by suicide and 2990 comparators were identified. Gambling diagnosis status was a significant predictor of suicide (odds ratio 30.94; 95% CI 3.57–268.28; P = 0.002). Individuals with gambling disorder had significantly more mental health treatment contacts (P < 0.001), particularly in-patient contacts (P < 0.001). No difference in out-patient contacts was found.
Conclusions
Historical diagnosis of gambling harm is a significant predictor of suicidal death and mental health treatment utilisation. Improved screening and coding practices would facilitate greater data linkage research on gambling-related suicide and suicide prevention.
A 103 km2 aerial lidar survey of Dzibanche/Kaanu’l, Mexico, reveals the city’s settlement to be more populous and well-organized than previously thought. The sprawling settlement incorporated the early center of Ichkabal in a network of smaller peri-urban civic-ceremonial nodes. The density and complexity of the Kaanu’l settlement is consistent with its extraordinary political reach as a multiregional hegemonic state. The city and settlement grew to their maximum extent during the Early Classic period until AD 630. The lidar-derived data show that Dzibanche may have had the largest monumental zone and highest population density in the Maya Lowlands at that time. The Early Classic layout was unaltered by later construction, allowing us to document a well-developed system of causeways connecting an urban center and peripheral plaza groups with surrounding settlements and agricultural fields. The spatial organization and interconnectedness of this Early Classic settlement suggests a greater level of urban planning for optimal flow of goods and people across urban and peri-urban zones than previously thought.
The decision to apply for EU membership has prompted significant legislative changes in Central and Eastern European countries, including Serbia. The focus on the single European market emphasizes the importance of product safety and quality. Establishing a National Quality Infrastructure (NQI) is crucial for good governance and fostering a favourable trade environment. This article aims to analyse how Serbian policymakers view quality infrastructure by examining parliamentary debates on four NQI laws, contributing to a better understanding of policy development in Serbia and similar countries in the region. Out of 266 parliamentary speeches at the joint hearings of NQI laws, 35 speeches of law proponents, ministers, and deputies were analysed in detail. The European solutions adopted in Serbia lacked sufficient critical evaluation of their applicability, leading to unjustified economic and social costs. The quality infrastructure laws were viewed merely as EU requirements, rather than essential measures with intrinsic value and relevance to Serbia.
Historical analysis of Ghana’s late colonial mine communities has been extensive and overwhelmingly dominated by organised and politically active male mineworkers. Questions regarding the linkages between formal and informal mining actors and cultural ideas in the broader mine communities have remained inadequately explored. This article makes a timely investigation by critically analysing a range of governmental and corporate archival documents and situating the discussion within the context of expansive literature on Asante, and complemented by oral histories. It centres on the Asante/Akan term “kankyema”—a sociocultural phenomenon which women transformed towards economic ends to navigate the late colonial political economy’s mining income disruptions. The article argues for the essential need to centre marginalised voices in understanding diverse agencies in African mining history and for a deeper reflection on the potentialities of contextual sociocultural ideas—notably, how marginalised actors invoke and evoke their capacities over different times.
Pulmonary embolism is said to be more common in clozapine-treated patients than either in patients treated with other antipsychotics or in the general population.
Aims
To explore clinical features and outcomes of clozapine-related pulmonary embolism in the UK.
Method
We studied UK Yellow Card reports recorded as clozapine-related respiratory, thoracic and mediastinal disorders, 1990–2022.
Results
Of 474 unique reports of people with clozapine-associated pulmonary embolism, 339 (59% male) remained after applying strict exclusion criteria. Of these, 164 patients (48%) died. The mean clozapine dose was 336.7 (range 25–1000) mg d−1 (N = 126). There was no difference in dose between the fatal and non-fatal outcomes. The median age at onset of pulmonary embolism was 45 years (range 21–82 years; N = 309). The median duration of clozapine treatment until onset was 2.9 years (range 2 days–22.7 years; N = 306). Sixty-five (39%) non-fatal and 36 (22%) fatal emboli occurred within 1 year of treatment. People who died were more likely to be obese (adjusted odds ratio 2.61; 95% CI 1.44–4.91) and to be noted as sedentary (adjusted odds ratio 6.07; 95% CI 1.58, 39.9). The 3 year moving average of cases was 0–5 per year, 1990–1999, 26 in 2010 and 16 in 2022. There was no change in the proportion of deaths by year of report (p = 0.41).
Conclusions
Clozapine-related pulmonary embolism is a significant concern with a high fatality rate. This risk necessitates a proactive approach to not only prevention, but also early recognition and management.
We investigate theoretically the breakup dynamics of an elasto-visco-plastic filament surrounded by an inert gas. The filament is initially placed between two coaxial disks, and the upper disk is suddenly pulled away, inducing deformation due to both constant stretching and capillary forces. We model the rheological response of the material with the Saramito–Herschel–Bulkley (SHB) model. Assuming axial symmetry, the mass and momentum balance equations, along with the constitutive equation, are solved using the finite element framework PEGAFEM-V, enhanced with adaptive mesh refinement with an underlying elliptic mesh generation algorithm. As the minimum radius decreases, the breakup dynamics accelerates significantly. We demonstrate that the evolution of the minimum radius, velocity and axial stress follow a power-law scaling, with the corresponding exponent depending on the SHB shear-thinning parameter, $n$. The scaling exponents obtained from our axisymmetric simulations under creeping flow are verified through asymptotic analysis of the slender filament equations. Our findings reveal three distinct breakup regimes: (a) elasto-plastic, (b) elasto-plasto-capillary, both with finite-time breakup for $n\lt 1$, and (c) elasto-plasto-capillary with no finite-time breakup for $n=1$. We show that self-similar solutions close to filament breakup can be achieved by appropriate rescaling of length, velocity and stress. Notably, the effect of the yield stress becomes negligible in the late stages of breakup due to the local dominance of high elastic stresses. Moreover, the scaling exponents are independent of elasticity, resembling the breakup behaviour of finite extensible viscoelastic materials.
Neural network (NN)-based control policies have proven their advantages in cyber-physical systems (CPS). When an NN-based policy fails to fulfill a formal specification, engineers leverage NN repair algorithms to fix its behaviors. However, such repair techniques risk breaking the existing correct behaviors, losing not only correctness but also verifiability of initial state subsets. That is, the repair may introduce new risks, previously unaccounted for. In response, we formalize the problem of Repair with Preservation (RwP) and develop Incremental Simulated Annealing Repair (ISAR). ISAR is an NN repair algorithm that aims to preserve correctness and verifiability—while repairing as many failures as possible. Our algorithm leverages simulated annealing on a barriered energy function to safeguard the already-correct initial states while repairing as many additional ones as possible. Moreover, formal verification is utilized to guarantee the repair results. ISAR is compared to a reviewed set of state-of-the-art algorithms, including (1) reinforcement learning-based techniques (STLGym and F-MDP), (2) supervised learning-based techniques (MIQP and minimally deviating repair) and (3) online shielding techniques (tube MPC shielding). Upon evaluation on two standard benchmarks, OpenAI Gym mountain car and an unmanned underwater vehicle, ISAR not only preserves correct behaviors from previously verified initial state regions, but also repairs 81.4% and 23.5% of broken state spaces in the two benchmarks. Moreover, the signal temporal logic (STL) robustness of the ISAR-repaired policies is higher than the baselines.
Why has political representation by Scheduled Castes in post-colonial India failed to improve the lives of the vast majority of this population? One common answer rests on the assumption that caste inequality is upheld by dominant social groups who effectively resist progressive state policy. Others point to the institution of joint electorates: though constituencies are reserved for Scheduled Caste legislators, Scheduled Caste voters form a minority within them; the representatives thus elected are chosen primarily by others, and precisely because they will not challenge the status quo, it is said. But neither of these explanations, I argue, can adequately account for the minimal effects of Scheduled Caste representation, because both imagine states as confronting a distinct realm—‘society’—with pregiven interest groups that are then represented in legislatures. Instead, an examination of how state actions themselves govern, produce, and reproduce caste groups and intercaste relations is required. The argument is illustrated through episodes from the career of Dr Sathiavani Muthu, who sought to address injustices suffered by Scheduled Castes in Tamil Nadu from the late 1950s through to the 1980s. Muthu’s skill, diligence, and commitment make her an ideal representative, and Tamil Nadu as a state ought to provide a best-case scenario for the success of such an actor, given the scholarly consensus regarding its good governance and the pervasion of its society with a progressive ideology. An analysis of why her efforts nevertheless produced little fruit reveals pervasive deficiencies in current models of political representation.
This research examines whether a machine, specifically artificial intelligence (AI), can be creative by comparing design solutions for a practical competition – a light fixture for a pediatric waiting room – among AI, collaboration efforts and a human designer. Amazon Mechanical Turk and Prolific workers observed the design solutions throughout the design process, from sketches ($ S $) to three-dimensional renderings ($ 3D $) to fully developed models in virtual waiting rooms ($ VR $). Using the well-established Creative Product Semantic Scale (CPSS), the workers rated each design solution in three distinctive stages – $ S $, $ 3D $ and $ VR $ – on three criteria – novelty (freshness or newness), resolution (relevance and logic) and style (craftsmanship and desirability). Despite some demographic discrepancies, the workers expressed general senses of happiness and calmness, resonating with the competition’s requirements. Statistical results of CPSS ratings revealed that while AI excelled in style for $ 3D $, the human designer outperformed in novelty for both $ S $ and $ VR $. Collaboration efforts surprisingly finished last. Such findings challenge current assumptions of AI’s creative ability in design research and highlight the need to be agile in the age of disruptive technologies. This research also offers guidance for product and interior designers and educators on thoughtfully integrating AI into the design process.
Why is exposure to political violence associated with both mobilising and demobilising outcomes? Community dynamics influence the local materialisation of violence engendered by supra-local political conflict. The reification of the driving political conflict as intracommunal or intergroup produces disparate outcomes. Exposure to violence may generate an enduring rift concretised through intimate bloodshed or could fashion a shared victimisation experience viable as a collective political mobilisation resource. In Cameroon, the Union des populations du Cameroun (UPC) opposed French colonialism through political action and guerilla warfare. Many saw the UPC as a heroic nationalist movement, others as murderers. Through interviews, I examine narratives that [re]construct social and political meaning out of conflict and death. These narratives of conflict are used to mobilise in places where the UPC was locally hegemonic and demobilise in politically competitive areas.
In England, Shiga toxin-producing Escherichia coli (STEC) serogroup O26 has recently emerged as a public health concern, despite fewer than half of diagnostic laboratories in England having the capability to detect non-O157 STEC. STEC O26 cases frequently report exposure to farms or nurseries. We describe the epidemiology of STEC O26 and examine evidence for a relationship between O26 and exposure to these settings. We analysed national surveillance data describing laboratory-confirmed STEC cases and public health incidents over the past 10 years to explore the incidence, clinical outcomes, and association with farms and nurseries for STEC O26 cases compared to STEC O157 and other serogroups. Between 2014 and 2023, the proportion of STEC notifications which were STEC O26 increased from 2% (19/956) to 12% (234/1946). After adjusting for age, we found no difference in the likelihood of farm or nursery attendance between O26 and O157 cases but a significantly higher risk of HUS in O26 (adjusted risk ratio 3.13 (2.18–4.51)). We demonstrate that STEC O26 is associated with the same risk of farm or nursery attendance as other STEC serogroups but a higher risk of severe morbidity. Our findings reinforce the need for improved surveillance of non-O157 STEC.
Acute gastrointestinal illness (AGI) remains a significant public health issue and differences in risk based on a comprehensive set of sociodemographic characteristics remain poorly understood. Thus, this retrospective cohort study was conducted to identify the risk of incurring an AGI-related emergency department (ED) visit or inpatient hospitalization based on various sociodemographic factors. Linked respondents of Canadian Community Health Survey cycles 2.1, 3.1, and 2007–2015 were followed from their interview date until 31 December 2017, using the National Ambulatory Care Reporting System (NACRS) and the Discharge Abstract Database (DAD) to capture emergency ED visits and hospitalizations due to AGI, respectively. Effects of identified potential risk factors for the incidence of AGI-related ED visits or hospitalizations were estimated Cox proportional hazards regression to generate hazard ratios (HRs) with 95% confidence intervals (CIs). A total of 190,700 respondents were linked to NACRS and 470,700 were linked to DAD. Six per cent of respondents visited an ED and 2% were hospitalized for AGI. Fully-adjusted estimates revealed that high-risk groups with the strongest effects were people with poor self-perceived health (ED visits: HR 1.47 (95% CI 1.40–1.54), hospitalizations: HR 1.92 (95% CI 1.82–2.02)), and people living with at least one chronic condition (ED visits: HR 1.54 (95% CI 1.47–1.61), hospitalizations: HR 1.65 (95% CI 1.57–1.73)). This study identified risk factors for requiring hospital care for AGI in the Canadian context. Additional research is needed to investigate mechanisms for differential exposure to pathogens by sociodemographic characteristics that might lead to increased risks of AGI.
In recent times, the effects of climate change, the COVID-19 pandemic and other natural disasters have undermined global efforts to reduce poverty and inequality among rural farmers. While efforts at mitigating the impacts of climate change, particularly in developing countries, have not yielded significant improvements, the global health crises of the COVID-19 pandemic have, in many ways, undermined the positive adaptations to climate change. Based on data produced through mixed methods, the paper explores how COVID-19 affected farmers’ ability to adapt to the changing climatic conditions in Ghana’s Coastal and Guinea savannah ecological zones. The paper argues that the disruption caused by the COVID-19 pandemic has undermined farmers’ access to markets, knowledge, innovations, technologies and critical inputs such as fertilisers, seeds and weedicides/herbicides/pesticides. This has decreased farm output, increased post-harvest loss and increased farmers’ vulnerability to the adverse effects of climate change.