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We consider the flow of a viscous fluid through a two-dimensional symmetric cross-slot geometry with sharp corners. The problem is analysed using the unified transform method in the complex plane, providing a quasi-analytical solution that can be used to compute all the physical quantities of interest. This study is a novel application of this method to a complicated geometry featuring multiple sharp corner singularities and multiple inlets and outlets. Our approach offers the advantage of resolving unbounded domains, as well as providing quantities of interest, such as the velocity and stress profiles, and the Couette pressure correction, from the solution of low-order linear systems. Our results agree well with the existing literature, which has largely used truncated bounded geometries with rounded or curved corners.
To evaluate eligibility and participation in nutrition assistance programmes (Supplemental Nutrition Assistance Program (SNAP) and Women, Infants and Children (WIC)) among transgender and gender diverse (TGD) adults in the USA and to capture their experiences when accessing food benefits.
Design:
This was a cross-sectional analysis of the US Transgender Survey (USTS) dataset – the largest survey of TGD adults in the US SNAP and WIC participation and experiences when visiting the public assistance office were reported using descriptive statistics; stratified analyses were conducted based on race using multivariate logistic regression modelling.
Setting:
The USTS was completed electronically in the USA.
Participants:
27 715 TGD adults.
Results:
Approximately 40·9 % of the full sample were SNAP eligible, yet only 30·6 % of those eligible were receiving the benefit; 0·45 % of the sample reported receiving WIC. TGD adults avoided the public assistance office because they feared being mistreated (3·2 %), were identified as transgender (46·2 %), were denied equal treatment (6·5 %) or were verbally harassed (5·2 %). People of colour were more likely to be denied equal treatment and verbally harassed at the public benefits office than their white peers. The impact of age, education level, employment status, relationship status and census region varied within each racial group.
Conclusions:
Far more TGD adults need food assistance compared with the general population, yet fewer are receiving the benefit. Culturally informed interventions are urgently needed to resolve the root causes of food insecurity, increase SNAP participation and address the negative experiences of TGD adults when accessing food benefits.
Aspects of the school food environment can influence food purchasing and consumption among adolescents, particularly those without access to a school meal programme. Our objective was to describe and compare food vendors of junior high schools (JHS) in Ghana.
Design:
We conducted structured observations of food vendors within a 0·25-km radius of eight JHSs. We compared foods sold and hygiene practices by vendor and community characteristics, such as on- v. off-campus location, urban v. rural, and predominant income-generating activity of the community. We also assessed the relationship between adolescent diet quality (food group diversity, all-5, NCD-protect and NCD-risk scores) and procurement method for foods consumed during the school day.
Setting:
Cape Coast and Elmina, Ghana.
Participants:
200 randomly selected students.
Results:
Of 265 identified vendors, 25·3 % sold foods on-campus. On-campus vendors were less likely to sell branded snacks (19·4 % v. 33·8 %, P = 0·001) and beverages (17·9 % v. 35·4 %, P = 0·008) and more likely to sell prepared dishes (53·7 % v. 31·8 %, P = 0·001) than off-campus vendors. Vendors practised an average of 38·8 % of applicable food hygiene practices, which did not differ by on- or off-campus location. In the previous month, 59·4 % of students most often purchased food on campus. There were no significant relationships between method of food procurement and diet quality.
Conclusion:
Many adolescents purchased food at school, and there were differences in foods sold by on- and off-campus vendors. School policies may be a promising avenue to alter food environments for adolescents.
We present a framework to calculate the scale-resolved turbulent Prandtl number ${\textit{Pr}}_t$ for the well-mixed and highly inertial bulk of a turbulent Rayleigh–Bénard mesoscale convection layer at a molecular Prandtl number of ${\textit{Pr}}=10^{-3}$. It builds on Kolmogorov’s refined similarity hypothesis of homogeneous isotropic fluid and passive scalar turbulence, based on log–normally distributed amplitudes of kinetic energy and scalar dissipation rates that are coarse-grained over variable scales $r$ in the inertial subrange. Our definitions of turbulent (or eddy) viscosity and diffusivity do not rely on mean gradient-based Boussinesq closures of Reynolds stresses and convective heat fluxes. Such gradients are practically absent or indefinite in the bulk. The present study is based on direct numerical simulation of plane-layer convection at an aspect ratio of $\varGamma =25$ for Rayleigh numbers $10^5\leqslant Ra\leqslant 10^7$. We find that the turbulent Prandtl number is effectively up to four orders of magnitude larger than the molecular one, ${\textit{Pr}}_t\sim 10$. This holds particularly for the upper end of the inertial subrange, where the eddy diffusivity exceeds the molecular value, $\kappa _e(r)\gt \kappa$. Highly inertial low-Prandtl-number convection becomes effectively a higher-Prandtl-number turbulent flow, when turbulent mixing processes on scales that reach into the inertial range are included. This might have some relevance for prominent low-Prandtl-number applications, such as solar convection.
This study documents and analyzes arthropod trackways from the Upper Cretaceous Wapiti Formation, located in west-central Alberta, Canada. In general, the ichnotaxonomy of arthropod trackways is problematic due to inconsistent use of diagnostic criteria in previous studies. Thus, the trackways from the Wapiti Formation are described following recently defined criteria to facilitate future ichnotaxonomic reevaluations. Judging primarily from the number and morphology of the imprints and the symmetry of the track series, the trackways are identified as Octopodichnus cf. O. raymondi Sadler, 1993. Other relevant track attributes include heteropody and great imprint depth. The mudstone slabs bearing the trackways also contain other well-preserved invertebrate trace fossils along with abundant silicified plant material. The silicified plant fragments, taken together with bentonite overlying the trace-bearing surface, suggest volcanic ash played a role in preserving the trackways. The associated traces include burrows, fecal mounds, and surficial marks and contribute to a diverse invertebrate trace-fossil assemblage. The Wapiti Formation trackways are attributed to crayfish or similar decapods and were emplaced in a succession interpreted to have been deposited in a swampy floodplain environment. By contrast, previously described examples of Octopodichnus have typically been attributed to arachnids in aeolian/desert environments. This paper expands the ichnological record of crayfish-like arthropods from the Late Cretaceous and contributes to the underexplored invertebrate fossil record of the Wapiti Formation and, more broadly, Cretaceous strata in the Western Canada Sedimentary Basin.
The present study examined the association of screen and sleep time, physical fitness and eating behaviour with Mediterranean diet (MD) adherence in a sample of preschoolers from Granada, Spain.
Design:
A cross-sectional, non-randomised design was employed. A multilinear regression model with backward elimination was used for analysis.
Setting:
Variables included age, screen time, hours of nightly sleep, physical fitness, food approach and food avoidance. The developed model met assumptions of multiple regression in terms of linearity, homoscedasticity, normality, independence and non-multicollinearity.
Participants:
Data were collected from 653 of the 2250 three-to-six-year-old children attending the eighteen schools invited to take part in the present study. Data on children’s behaviours were parent-reported using validated questionnaires.
Results:
Better sleep time and lower screen time and food avoidance were found to be predictive of MD adherence. These variables explained 15 % of the variance in preschoolers’ MD adherence.
Conclusions:
The present study suggests that sleep and screen time and food avoidance are important components to consider when targeting improvements in MD adherence in preschoolers. Future research should explore the way in which parental health behaviours influence their children’s health habits in order to better understand the outcomes.
The role of healthcare provider ownership in shaping health system performance remains contested. An umbrella review was conducted to synthesise evidence on the relationship between healthcare provider ownership and performance in high-income countries. Systematic reviews were included that examined performance of healthcare providers based on ownership status. Searches yielded 1,862 results, with 31 systematic reviews meeting the inclusion criteria, and one further systematic review identified through grey literature searches. Following the exclusion of 10 reviews classified as low-quality and two previous umbrella reviews both published in 2014, 20 reviews were eligible for data extraction and synthesis. Inconsistent evidence was found across reviews between healthcare provider ownership and several performance indicators including health outcomes, technical efficiency, and patient satisfaction. Private hospitals tend to serve wealthier patients, select less complex or costly patients, and charge higher payments for care than public comparators. Private for-profit (FP) providers of hospital and long-term care generally had poorer workforce outcomes than private not-for-profit or public providers, including reduced staffing levels, higher workloads, and lower job satisfaction. Private PF hospitals and nursing homes had improved financial performance based on revenues or profit margins. Our findings underscore the need for nuanced regulatory responses to the expansion of private FP provision within publicly funded systems.
Governments across the world are leveraging artificial intelligence (AI) to render services to citizens. Emerging economies are not left behind in this transformation but remain a gaping distance behind in their integration into public-sector service delivery compared to the private sector. To ensure the effective integration of AI services by government agencies to serve citizens, it is necessary to understand the constellation of factors driving user adoption of AI. Therefore, this study answers the question: how can government-initiated AI services be successfully accepted by citizens? Leveraging non-probability sampling, a snowball sample of 245 tertiary student-workers from across Ghana was surveyed to solicit their knowledge, attitudes, readiness, and use intentions towards AI-enabled government services. The data were analysed using FsQCA and complemented by PLS-SEM to confirm the findings. The findings reveal four unique configurations, summarised into two broad groups; AI enthusiasts and AI sceptics that drive AI adoption in government services. Positive readiness factors, such as knowledge of AI and optimism towards AI, characterise AI enthusiasts. In contrast, those described as AI sceptics still adopt government AI services despite their reservations and general distrust. AI sceptics are a delicate group that sit at the boundary between adoption and rejection, requiring special attention and strategies to orient them towards adoption. The study recommends effective education and trust-building strategies to foster AI adoption in government services. The findings are essential for driving the efficient implementation of AI-enabled services among working-class citizens in emerging economies.
This study aims to examine the awareness, attitudes, and acceptability of medical aid in dying (MAiD) among healthcare professionals in Pakistan, a predominantly Muslim country where cultural and religious values heavily influence medical ethics and end-of-life decisions.
Methods
A cross-sectional survey was conducted online among 70 healthcare professionals, including physicians, nurses, and allied health workers in Pakistan. Data were collected via a structured, self-administered online questionnaire assessing knowledge, attitudes, and willingness to participate in MAiD-related actions. Descriptive and correlational analyses were conducted to identify patterns and associations.
Results
Participants demonstrated moderate knowledge about MAiD (M = 17.13, SD = 3.42) and moderate support for its legalization (M = 18.89, SD = 4.99). However, levels of negative attitudes (M = 32.21, SD = 6.11) and legal and ethical concerns (M = 24.73, SD = 3.66) were high. Behavioral willingness to engage in MAiD-related actions remained low (M = 2.42, SD = 3.38), with limited intent to assist (M = 0.39), refer (M = 0.64), or approve physician-assisted MAID (M = 0.81). A significant negative correlation emerged between knowledge and support for legalization (r = − .25, p = .037), while no significant associations were observed between knowledge and willingness to participate in MAiD. Gender and profession did not significantly influence attitudes or willingness.
Significance of results
While Pakistani healthcare professionals display a conceptual understanding of MAiD, their readiness to participate remains low, primarily due to ethical, legal, and religious concerns. These findings highlight the need for creating awareness regarding MAiD and for providing culturally sensitive education, structured training in palliative care, and the development of clear legal frameworks to guide end-of-life decision-making in Muslim-majority contexts.
To explore the experiences of military medical first responders managing mass casualty incidents (MCIs) during the ongoing conflict in Ukraine to identify key challenges and insights.
Methods
This qualitative study employed in-depth, semi-structured interviews with medical first responders who managed MCIs in Ukraine. Thematic analysis was leveraged by our research team to identify recurring themes and patterns within the interview data.
Results
Our results revealed crucial takeaways related to the (1) need for preparedness and training, (2) variability of triage, (3) importance of communication and teamwork, and (4) the resulting psychological strain.
Conclusions
These firsthand accounts offer valuable lessons for identifying challenges of first responders, developing areas of future research for MCI response strategies, and enhancing the readiness and well-being of medical first responders in current and future conflicts.
This study assessed iron-rich food consumption and its associated factors among children aged 6–23 months in South and Southeast Asia.
Design:
A cross-sectional study from the Standard Demographic and Health Survey (2015–2022).
Setting:
South and Southeast Asian countries.
Participants:
Data collected from 95 515 children aged 6–23 months, including information from their parents or caregivers.
Results:
The overall proportion of children, aged 6–23 months, consuming iron-rich foods in the region was 29·87 % (95 % CI: 29·58, 30·16). Higher odds of iron-rich food consumption were observed among children aged 12–23 months (adjusted OR (AOR) = 3·59; 95 % CI: 3·45, 3·76), had history of exclusive breast-feeding (AOR = 1·17; 95 % CI: 1·12, 1·23), born to teenage motherhood (AOR = 1·09; 95 % CI: 1·02, 1·17), born in health institution (AOR = 1·10; 95 % CI: 1·02, 1·19) and had pregnant mother at the time of the survey (AOR = 1·60; 95 % CI: 1·50, 1·72). Children of birth order 2–4 (AOR = 1·26; 95 % CI: 1·20, 1·32) and 5+ (AOR = 1·29; 95 % CI: 1·18, 1·43), from female-headed households (AOR = 1·06; 95 % CI: 1·01, 1·12) and those with household mass media exposure (AOR = 1·27; 95 % CI: 1·19, 1·36) also had significantly higher odds of iron-rich food consumption. Additionally, higher odds ratio (OR) (AOR > 1) of iron-rich food consumption were observed in Cambodia, Bangladesh, Indonesia, Myanmar, Maldives, Philippines, Pakistan and Timor-Leste.
Conclusion:
Across countries, only about 30 % of children consumed iron-rich foods, with significant variation. Targeted public health efforts are essential to address maternal, child and household factors that influence intake.
Patients with chronic liver disease (CLD) often experience hypozincemia. The clinical factors associated with hypozincemia have not been established. We investigated clinical factors that may be useful to predict hypozincemia in patients with CLD. The serum zinc levels CLD patients were measured; Study 1 investigated the predictive factors of hypozincemia, and Study 2 was performed to validate the factors identified in Study 1. Study 1 included 197 participants, of whom 28 and 106 had serum zinc levels <60 µg/dL and <80 µg/dL, respectively. A multivariate analysis revealed that serum zinc levels <60 µg/dL or <80 µg/dL were associated with the albumin–bilirubin (ALBI) score and serum albumin level. A receiver operating characteristic curve analysis revealed that the ALBI score ≥ −1.83 and the serum albumin level ≤3.3 g/dL were the cut-off values for a serum zinc level <60 µg/dL, whereas the ALBI score ≥ −2.44 and the serum albumin level ≤3.6 g/dL were the cut-off values for a serum zinc level <80 µg/dL. In Study 2 (n = 177), the diagnostic accuracy rates for serum zinc <60 µg/dL were 81.9% for the ALBI score and 75.1% for the serum albumin level, and those for serum zinc <80 µg/dL were 70.1% for both parameters. Together these findings indicate that the ALBI score may serve as a predictive factor of hypozincemia in CLD patients.
The use of metaphors, whether linguistic or visual, has been shown to enhance advertisement effectiveness, and sensory marketing research highlights the positive effects of appealing to consumers’ sensory perception. Synaesthetic metaphors, which involve metaphor and sensory experiences, are ideal for studying the effects of both metaphor and (multi)sensory cues in advertisements. We experimentally tested the hypothesis that the presence of (linguistic and/or visual) metaphor and the evocation of multiple senses will enhance advertisement appreciation and the intention to purchase the advertised product. We manipulated eight print advertisements, each of which was presented in the following conditions: (1) visual and linguistic synaesthetic metaphor; (2) linguistic but no visual synaesthetic metaphor; (3) visual but no linguistic synaesthetic metaphor; and (4) neither visual nor linguistic synaesthetic metaphor. Each advertisement was also rated for its multisensoriality, that is, its association with the five basic senses. Results partly supported the hypothesis, showing that advertisements with both visual and linguistic synaesthetic metaphors and those perceived as more multisensory were most appreciated. However, purchase intentions were not influenced by either metaphor or multisensoriality. This indicates that higher aesthetic appreciation does not necessarily translate into higher purchase intentions, suggesting the need for further research into additional influencing factors.
This study aimed to evaluate adult women’s cooking (CS) and food preparation skills (FPS) and their nutrition literacy (NL) levels and to examine the relationship between these two concepts.
Design:
Data were collected via face-to-face interviews using a personal information form, the Cooking and Food Preparation Skills scale, and the Evaluation Instrument of Nutrition Literacy on Adults. Data were analysed with SPSS, with P < 0·05 considered significant.
Setting:
Female adults aged 20–64 years who participated in family support courses in Tepebaşı, Eskişehir, Turkey.
Participants:
The study sample consisted of 330 female individuals between the ages of 20 and 64 years who agreed to participate in the survey.
Results:
NL was generally adequate (91·8 %), though gaps were identified in portion knowledge (54·2 %) and food label reading (44·2 %, borderline). Higher literacy levels were associated with being younger, more educated and employed (P < 0·05). CS and FPS were higher among married women and those with children. Cooking frequency and enjoyment significantly influenced these skills (P < 0·05). Those who cooked more often had higher scores in food label reading and basic math (P < 0·001) and higher total scores (P = 0·049). Participants who enjoyed cooking had better reading comprehension (P = 0·030). A weak but significant correlation was found between FPS and general nutrition knowledge, but no strong relationship was observed between overall cooking skills (CS) and total NL.
Conclusion:
Although no strong link was found between NL and CS, these skills appear to support healthier eating behaviours. Promoting cooking and food preparation through nutrition education may help improve public health.
Both host identity and environmental factors are known to influence parasite species richness. Here, we analysed selected host traits and environmental variables associated with 3 aspects of helminth diversity in African ruminants. Based on the helminth faunas of 35 species of antelope and 1 species of giraffe, we studied drivers of species richness as well as taxonomic and functional diversity, combined for all helminths and separately for nematodes, cestodes and trematodes. A larger geographic host range and/or multiple habitats were associated with higher species richness in all helminths and each group individually as well as with functional diversity in all helminths, trematodes and cestodes. A wider host distribution range and larger relative brain size were both linked to higher taxonomic diversity in all helminths, and an increase in host longevity was linked to higher taxonomic diversity in nematodes. A higher level of climate moisture, relative humidity and primary production had a positive effect on trematode species richness and taxonomic diversity in all helminths, while trematode taxonomic diversity decreased in hosts from drier areas but increased in cestodes harboured by hosts from warmer areas. Our results highlight that patterns in parasite species richness and diversity emerge from an interplay of numerous factors, including host biology, environmental conditions and ecological traits of the parasites themselves. This points to the importance of carefully choosing the range of hosts considered for large-scale parasite diversity studies and underscores the need to avoid grouping too many types of parasites when looking for ecological patterns.
In team science, invitation to writing groups can be subjective and secretive. Confronted with this challenge in the ISCHEMIA trial, with 320 participating sites, 4 coordinating centers, 6 core laboratories, and numerous committees, we adapted an existing model to develop a transparent, objective, and equitable method for determining authorship eligibility.
Methods:
We developed a scoring system based on site performance of tasks critical to trial success that meet the ICJME criteria for authorship. Sites were ranked according to points earned, and points required for potential authorship were communicated to all sites. Site investigators were surveyed for their manuscript topic preferences for writing groups. Beyond the point-based system, authorship positions were also reserved for trial contributors who were not site investigators.
Results:
To date, 50 original, peer-reviewed ISCHEMIA trial manuscripts have been published. In total, 208 authors from 33 countries participated in at least one publication. Of the 87 sites that randomized at least 15 participants over a mean of 5 years, 72% had authorship positions across published manuscripts. Surveys were sent to 334 site investigators and 27% responded. Among respondents, 61% indicated that ISCHEMIA was the first trial they had worked on with performance-based criteria for authorship invitation. Respondents agreed the system was transparent (81%), objective (83%), and equitable for early career researchers (70%) and underrepresented minorities in research (57%).
Conclusions:
ISCHEMIA employed a point-based authorship eligibility system that most authors found objective, merit-based, transparent, and equitable. Implementation of such a system should be considered for team science publications.
What are the benefits of access to the bond market for unlisted firms, and how does it affect their bank lending conditions? Using a regulatory reform that allowed unlisted firms to issue minibonds, we address these questions comparing new bank loans to issuers with concurrent loans to matched non-issuers. After the first minibond issuance, issuers obtain lower interest rates on bank loans of similar maturity, largely reflecting a shift in the seniority structure of corporate debt, and reduce the use of bank loans while increasing their total financial debt. They also increase turnover, total and fixed assets, particularly intangible assets.
This study aimed to investigate (1) the longitudinal associations between food patterns and body weight in young adulthood and (2) how food patterns of young adults relate to food consumption in early, middle and late childhood. The study sample includes 700 participants of the Québec Longitudinal Study of Child Development. During childhood, frequency of consumption of various foods was reported on ten occasions between 1·5 and 13 years. At age 22 years, food frequency questions (with quantities) were used to derive four food patterns (labelled healthy, beverage rich, protein rich and high energy density) through exploratory factor analysis. Self-reported height and weight were collected at 22 and 23 years. Regression analyses were performed to assess the associations between (1) food patterns and weight outcomes a year later (BMI, BMI change and overweight status) and (2) frequency of consumption of eight food groups in childhood and food patterns in adulthood. Dietary habits characterised by the consumption of vegetables, fruit, plant-based sources of protein and whole-grain cereal products were related to a lower risk of obesity a year later. Conversely, dietary habits characterised by a high consumption of energy-dense foods, of animal sources of proteins and, among women, of high quantities of liquids were associated with higher risk of excess weight a year later. Healthier food choices in childhood were associated with healthier food patterns in young adulthood. These findings reinforce the value of preventive dietary interventions in the early years to foster eating environments that favour healthy eating and healthy weights in adulthood.
Understanding ice flexural behavior is essential for assessing interactions with structures in cold environments. The mechanical response of ice depends on microstructural properties, such as grain size and porosity, which vary widely in natural ice. Existing bending test data often lack detailed microstructural characterization, making it difficult to interpret or generalize the results. In brittle materials such as concrete or rock, pores commonly act as failure-initiating defects. Therefore, porosity (pore size, shape and density) should be considered a key parameter when studying ice fracture. Here, we provide a robust set of bending experiments on well-controlled isotropic polycrystalline ice microstructures and investigate the role of porosity in ice failure. Two porosity levels were studied, characterized at high resolution by micro-computed X-ray tomography. Analyzing the bending failure by means of the Weibull model reveals that the sample failure is initiated by different defect populations, in relation to the porosity. Providing that the Griffith/Irwin failure criterion can be applied, the measured pore distribution allows the prediction of a critical stress for defect activation. Compared with measured failure stress, this prediction enables discriminating the defect population responsible for failure and offers a mechanistic interpretation of the volume effect observed in porous ice flexural strength.
Professor Stephan Harbarth obtained his medical degree from the University of Munich in 1993. He completed postgraduate training in internal medicine and infectious diseases in both Munich and Geneva. After serving as a clinical research fellow in infectious diseases at Geneva University Hospitals (HUG), he pursued postgraduate studies in epidemiology at Harvard School of Public Health, earning a Master of Science in Epidemiology in 1999. He continued his research activities at Children’s Hospital of Harvard Medical School until 2001.
In April 2007, he was appointed Attending Physician in the Infection Prevention and Control Service (SPCI) at HUG and also served as a consultant in the Infectious Diseases Service. He became head of the SPCI in October 2022.
A Privat-docent at the Faculty of Medicine since 2006, Professor Harbarth was appointed Associate Professor in 2010 and Full Professor in 2018. His research focuses on the epidemiology and prevention of antibiotic-resistant infections, as well as on antibiotic stewardship. A renowned expert in this field, he serves on numerous national and international expert committees. His work has received multiple awards, including the prestigious Robert Koch Award in 2022 for hospital hygiene and infection prevention.
His research group focuses on clinical and epidemiological studies aimed at addressing key issues related to the control of acquisition, transmission, and infection by multidrug-resistant organisms, as well as the associated clinical and public health burden. His work on the impact and control of nosocomial transmission of methicillin-resistant Staphylococcus aureus (MRSA) and extended-spectrum beta-lactamases (ESBL)-producing organisms has significantly improved strategies to combat these pathogens. His additional research interests include the molecular epidemiology of emerging bacteria, pharmaco-epidemiology and antibiotic optimization, and the rapid diagnosis of severe infections. He has been involved in several large-scale, EU-funded studies (REVERSE, ECRAID, COMBACTE) and led the major European project “Drive-AB,” which coordinated over 20 public and private partner institutions across 12 European countries to address this public health threat.
Professor Stephan Harbarth was included in the Highly Cited Researchers™ 2022 list.