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The content of Kant’s Enlightenment text has received much critical reception, but the very stance Kant takes as its author has been largely ignored. Similarly, there has been much critical discussion of Horkheimer and Adorno’s “Dialectic of Enlightenment” in terms of the theses they (purportedly) endorse, while their authorial voice has mostly received either no attention or been criticised as problematically rhetorical. In this paper, I take a different approach, focusing on the two respective writerly stances. I suggest that Kant’s text harbours an implicit epistemic authoritarianism, in contrast to the self-therapeutic stance Adorno and Horkheimer’s text exemplifies.
Exploring 'early globalism and Chinese literature' through the lens of 'literary diffusion,' this Element analyzes two primary forms. The first is Buddhist literary diffusion, whose revolutionary impact on Chinese language and literature is illustrated through scriptural translation, transformation texts, and 'journey to the West' stories. The second, facilitated diffusion, engages with the maritime world, traced through the seafaring journey of Cinderella stories and the totalizing worldview in literature on Zheng He's voyages. The authors contend that early global literary diffusion left a lasting imprint on Chinese language, literature, and culture. This title is also available as Open Access on Cambridge Core.
To understand current practices for screening, implementing and clearing contact precautions (CP) for multidrug-resistant organisms (MDRO).
Design:
A survey of US-based SHEA Research Network (SRN) members and Community Healthcare Epidemiologists and Stewards (CHES).
Participants:
The SRN is a consortium of healthcare facilities collaborating on multicenter research projects. CHES is an SRN-affiliated group of community hospital epidemiologists.
Methods:
A Research Electronic Data Capture (REDCap) survey was administered between January 7, 2025 and February 25, 2025. Frequencies and proportions were calculated in REDCap and Microsoft Excel. Fisher’s exact and χ2 tests were calculated in R.
Results:
Of 134 facilities, 60 (45%) responded; 4 answered only demographic questions and were excluded from analysis. Most facilities (70%) performed active surveillance for ≥1 MDRO, but only 16% employed preemptive CP. All respondents reported using CP for ≥1 MDRO. CP were employed more often for infection than colonization. Clearance protocols to discontinue CP were common for MRSA (97%), C. difficile (95%), and vancomycin-resistant enterococci (82%), but uncommon for Gram-negatives. Training and adherence of frontline staff (70%), unavailability of private rooms (41%), and lack of evidence-based strategies to eradicate reservoirs (34%) were the top 3 identified barriers to MDRO infection control and prevention.
Conclusions:
Infection control practices varied by infection, colonization, specific MDRO, and time to clearance. Variation may indicate need for more data on transmission risk by disease state, organism, and time. Evidence-based strategies are needed to guide MDRO prioritization and CP duration and clearance policies. Guidance should acknowledge limitations in adherence, availability of private rooms, and persistent environmental reservoirs as major barriers to MDRO containment identified in this survey.
This study used the trials of improved practices (TIPs) approach to explore complementary feeding practices among caregivers of children under two and assess the acceptance of new nutritional supplements by providing microbiota-directed supplementary food (MDSF), ready-to-use supplementary food (RUSF) and locally available food (LAF) among moderately malnourished children.
Design:
The study was conducted between May and October 2022 in preparation for a larger trial. The first phase focused on complementary feeding, hygiene, breast-feeding and responsive feeding practices using in-depth interviews and observations. The second phase involved counselling sessions and providing food supplements for forty-five participants. Follow-up visits evaluated acceptability and challenges faced during this period.
Setting:
Bauniabadh slum, Mirpur, Dhaka.
Participants:
Sixty-five children aged 6–24 months with moderate wasting and their caregivers.
Results:
Findings from IDI and observations revealed poor handwashing practices, with most caregivers washing only with water, and inconsistent use of soap. Only a minority boiled drinking water or cleaned utensils with soap. Responsive feeding practices were also limited, with frequent mobile phone use during feeding and lack of attention to the child. Among the three food interventions, LAF received the highest hedonic ratings across all sensory attributes, with a mean taste score of 5·7±1·4, compared with MDSF (4·8±1·9) and RUSF (4·7±1·6), although median consumption was similar across all supplements (75%).
Conclusion:
The TIPs approach identified context-specific caregiver behaviours and feeding preferences. These findings will guide the upcoming trial and assist policymakers and program planners in developing culturally tailored interventions to address childhood malnutrition in urban slums.
Quality of life (QoL) is an important clinical outcome in mental health. However, evidence on its progression and predictors in individuals at clinical high risk for psychosis (CHR-P) remains limited. This meta-analysis examined correlates, impact, and longitudinal changes in QoL among CHR-P individuals.
Methods
Following PRISMA guidelines (PROSPERO: CRD42024560092), we systematically searched multiple databases from inception to 27 May 2025. Eligible studies included CHR-P participants assessed with validated QoL instruments. Data extraction was performed independently, and meta-analyses, meta-regressions, heterogeneity, and publication bias analyses were conducted. Risk of bias was evaluated using a modified Newcastle–Ottawa Scale (NOS).
Results
Thirty-one studies were included (2,288 CHR-P individuals; mean age = 21.47 years; 48.9% female). Compared with healthy controls (HC), CHR-P participants showed significantly poorer QoL (Hedges’ g = 1.39, 95% CI = 0.97–1.83). Longitudinal analyses indicated QoL improvements after 1 year (Hedges’ g = 1.40, 95% CI = 0.74–2.07) and at 2–3 years follow-up (Hedges’ g = 3.24, 95% CI = 0.73–5.75). Substantial heterogeneity was observed across analyses. Meta-regressions showed no significant influence of age, sex, functioning, symptom severity, or study quality. Study quality scores ranged from 1 to 8 (median = 6, mean = 5.8, SD = 1.13).
Conclusions
Individuals at CHR-P present markedly poorer QoL compared with healthy controls. Longitudinal data suggest possible improvements over time; however, heterogeneity and limited long-term evidence warrant cautious interpretation. Further longitudinal studies are needed to better characterize QoL trajectories and identify subgroups requiring sustained intervention.
AI’s growing role in finance challenges traditional expectations of transparency and theoretical understanding. While machine learning (ML) models enhance financial decision-making, they remain largely agnostic to established financial theories, producing knowledge and ignorance in ways that differ from traditional models like VaR, DCF, and Black-Scholes. This essay explores the decoupling of AI models from theoretical financial knowledge and the resulting forms of ignorance. Using 22 semi-structured interviews, we investigate how ML models generate epistemic uncertainties. We focus on causal ignorance: AI systems, including those supported by XAI, fail to provide genuine causal explanations. Because understanding causation is inherently theoretical, AI-driven finance remains theory-agnostic and marked by theoretical ignorance. We explore how this ignorance differs from that of traditional models and what it implies for the role of theory in finance. Finally, we present three possible scenarios for the future of theory in finance and outline directions for further research.
Motivated by recent breathtaking progress in the synthetic study of Lorentzian geometry, we investigate the local concavity of time separation functions on Finsler spacetimes as a Lorentzian counterpart to Busemann’s convexity in metric geometry. We show that a Berwald spacetime is locally concave if and only if its flag curvature is nonnegative in timelike directions. We also give another characterization of nonnegative flag curvature by the convexity of future (or past) capsules, inspired by Kristály–Kozma’s result in the positive definite case. These characterizations are new even for Lorentzian manifolds.
Bipolar disorder (BD) involves immune-inflammatory dysregulation. This systematic review and meta-analysis assessed complete blood count-based inflammatory indices – neutrophil-to-lymphocyte (NLR), monocyte-to-lymphocyte (MLR), and platelet-to-lymphocyte (PLR) ratios – in BD versus healthy controls (HCs), major depressive disorder (MDD), and across BD mood states.
Methods
Databases were searched through June 2025 for observational studies reporting at least one ratio in adults with BD and including as comparators either HCs, MDD, or within-BD mood-state contrasts (mania, bipolar depression, euthymia). Quality was appraised using BIOCROSS. Random-effects meta-analyses, sensitivity analyses, and meta-regressions were performed. GRADE was adapted to rate evidence certainty.
Results
Fifty-one studies (38,309 participants) met the inclusion criteria. Compared to HCs, BD showed higher NLR (SMD = 0.44, p < 0.001) and MLR (SMD = 0.28, p < 0.001). In mania, NLR (SMD = 0.62, p < 0.001), MLR (SMD = 0.51, p < 0.001), and PLR (SMD = 0.18, p = 0.014) were all elevated versus HCs. Depression showed lower PLR (SMD = –0.14, p < 0.001) and euthymia higher NLR (SMD = 0.37, p = 0.002). Compared to MDD, BD had higher NLR (SMD = 0.21, p < 0.001) and MLR (SMD = 0.18, p < 0.001). Similarly, mania showed higher NLR (SMD = 0.53, p < 0.001) and MLR (SMD = 0.41, p < 0.001), while bipolar depression lower PLR (SMD = –0.15, p < 0.001). Mania had higher NLR (SMD = 0.32, p < 0.001), MLR (SMD = 0.32, p < 0.001), and PLR (SMD = 0.14, p = 0.028) than depression and higher MLR than euthymia (SMD = 0.44, p = 0.027), while depression had lower NLR (SMD = –0.28, p = 0.012) and PLR (SMD = –0.22, p < 0.001). Evidence certainty was mixed.
Conclusions
NLR, MLR, and PLR emerge as non-specific, group-level correlates of immune-inflammatory dysregulation in BD, however offering limited discrimination between bipolar and unipolar depression. Notwithstanding their potential role as trait- and state-related markers in BD, further studies are needed to support translation into clinically useful biomarkers.
This study examines aspects of women’s empowerment related to the nutritional status of under-five children in Bangladesh, including their age-appropriate food intake and access to healthcare during acute respiratory tract infection (ARI).
Design:
Three waves of the Bangladesh Demographic Health Survey (BDHS) data (2011, 2014 and 2017–2018) were pulled and utilised to construct three domains of the Survey-Based Women’s Empowerment Index, such as social independence, intrinsic agency and instrumental agency. The height-for-age Z (HAZ), weight-for-age Z (WAZ) and weight-for-height Z (WHZ) scores were used to measure the nutritional status of offspring. Two variables were generated to measure age-appropriate food intake and treatment-seeking from medically trained providers (MTP) at the commencement of ARI. Generalised structural equation modelling was performed to develop pathways between women’s empowerment and children’s nutritional status.
Settings:
Data were collected from eight administrative divisions in Bangladesh.
Participants:
A total of 18 706 married women aged 15–45 years residing with their husbands and having at least one under-five child.
Results:
Women’s social independence was positively associated with HAZ (0·25 (95 % CI: 0·22, 0·28)), WAZ (0·21 (0·18, 0·24)) and WHZ (0·06 (0·02, 0·09)). Intrinsic agency positively influenced HAZ (0·03 (0·02, 0·04)) and WAZ (0·02 (0·01, 0·02)). Both social independence and intrinsic agency promoted appropriate feeding, while instrumental agency had a negative effect on food consumption (–0·0026 (–0·005, –0·0002)). Both age-appropriate food intake and seeking treatment from MTP during recent ARI episodes improved nutritional outcomes of offspring.
Conclusion:
Maternal social independence and intrinsic agency enhance the nutritional status, food consumption and healthcare access of offspring in Bangladesh.
The Chancellor of the Exchequer, Rachel Reeves, has described the UK economy as being in its worst state since 1945. Unlike the Labour Government of 1945, Reeves has rejected Beveridge-style public investment, in part because of claims of public support for fiscal restraint. We report findings of innovative, iterative mixed-methods survey (1) n = 693; 2) n = 10; 3) n = 2200) analysis of a programme for progressive tax reform designed to achieve comparable post-war outcomes conducted between November 2023 and January 2024 of adult UK residents. We analyse the findings of survey 3 to assess public support for the policy, impact of narratives and associations with demographic, socio-economic and health data. We find high levels of support for tax and spend, particularly where burdens are placed on wealth and business; significant impact of four narratives to persuade initial opponents to support the policy thematically organised around absolute gains, relative gains, security and environmental benefit; and clear associations between risk of destitution and various other socio-economic characteristics, health status and levels of support. We present structural equation modelling (SEM) of these associations and find moderately strong positive correlations with levels of support for key infrastructural policies. This suggests high levels of support for progressive taxation.
Corn poppy (Papaver rhoeas L.) is a problematic weed in cereal farms in Ireland, necessitating continuous herbicide use to protect crop yields. In 2022, poor control with acetolactate synthase (ALS) inhibitors and auxin-mimic herbicides was reported by growers/advisors in two resistance-suspect populations, namely PAPRH-R1 and PAPRH-R2. In this study, we quantified their resistance to both herbicide modes of action and investigated the underlying mechanisms. ALS inhibitor dose–response experiments revealed that both populations had ED50 and GR50 resistance indices (RIs) above 120 to thifensulfuron + tribenuron, mesosulfuron + iodosulfuron + amidosulfuron, and metsulfuron, and values of 4 to 13 to florasulam + pyroxsulam. Results of 2,4-D dose–response assays revealed higher resistance in PAPRH-R2 (ED50 and GR50 RI > 9.1) than PAPRH-R1 (ED50 and GR50 RI > 3.4). ALS gene sequencing detected Pro-197 mutations in all sequenced plants from both resistant populations. Pretreatment with piperonyl butoxide (PBO, a cytochrome P450 inhibitor) reversed 2,4-D resistance with GR50, the more sensitive response parameter, decreasing from 680.8 to 84.9 g ha−1 in PAPRH-R1 and from 2,508.9 to 456.8 g ha−1 in PAPRH-R2, both well below the recommended label rate of 1,000 g ha−1. The 14C-2,4-D assays ruled out reduced absorption or translocation as resistance mechanisms. Sensitivity screening further revealed incomplete control with other postemergence foliar herbicides tested at half and full recommended label rates, except for fluroxypyr + halauxifen, which provided complete control of PAPRH-R1 at the full rate, and glyphosate, which provided complete control of PAPRH-R1 and PAPRH-R2 at both rates. This is the first report of multiple resistance in P. rhoeas in Ireland involving ALS target-site mutations and likely P450-mediated 2,4-D metabolism. As cultural/nonchemical control of broadleaf species is difficult, the continued availability of preemergence or autumn residual herbicides, together with effective auxin mimics and stewardship practices, will remain essential for managing these species, including P. rhoeas, in cereal crops.
Readings of the history of penal expertise trace its rise to the late nineteenth century and its decline to the late twentieth century, with the crumbling of the welfare state. Despite stark differences along Whiggish and Foucauldian lines in evaluations of that history, a consensus has emerged that the penal-welfare complex peaked around mid-century, dependent on correctional experts. Most studies of that phenomenon have focused on the institutionalization and “treatment” of “problem” populations while neglecting the role of penal expertise in critiques of capital punishment. When Britain and Canada undertook major inquiries into the death penalty in the 1950s, they turned to the world’s foremost expert on the subject: sociologist Thorsten Sellin. Yet, these government-appointed studies devalued his academic capital in favor of the lived expertise of police. By examining the contestation of Sellin’s sources, methods, and conclusions, this paper puts the chronology of penal welfarism and its experts into question. Not simply a case of ill-informed opinion prevailing over criminological evidence, the dismissive treatment of this penal expert highlights the need to apply a more capacious understanding of contending forms of expertise at numerous points in penal history, rather than setting the devaluation of penal expertise in the recent past.
Parenting is related to the development of callous-unemotional (CU) traits (i.e. low empathy and restricted guilt), making it an important target of interventions for childhood conduct problems (CPs). However, the relative importance of different parenting features in relation to the development of CU traits remains unclear. This study used machine learning to examine multiple parenting features assessed across infancy and early childhood as predictors of CU traits and CPs in early adolescence.
Methods
Data were from the Family Life Project (N = 1,292; 49% female, 41% Black, and 28% below the poverty line). Seventy-four parenting predictors were assessed at eight time points between children aged 6–90 months using parent-reported questionnaires and observer ratings of videotaped interactions and home visits. CU traits and CPs were assessed via parent-reported questionnaires in preadolescence (12–14 years).
Results
Parenting features explained 8.2% of CU traits variability in preadolescence, with top predictors including early sensitive parenting and later behavior management and scaffolding practices. Prediction of CPs was weaker, with parenting explaining 4.5% of the variability.
Conclusions
Results highlight that disruption in close and sensitive early parent–child relationships is relevant to the development of CU traits. Results from the prediction of CPs indicate a more heterogeneous etiology. Findings support targeting parental sensitivity and behavior management within preventative interventions for CU traits and CPs.
The present study investigated how initial proficiency impacted development in adolescent learners’ L2 speaking. The study reports on a longitudinal study with dense measurements with twelve adolescent L2 English learners. The participants were tested every week throughout their first year of secondary school (30 datapoints). The participants’ learning trajectory was modeled using generalized additive mixed models (GAMMs). Results showed large differences in development between various lexical and syntactic measures and between individual learners. The learners’ initial proficiency had a significant impact on their development. Overall, more periods of growth were observed in lexical measures than in syntactic measures. In line with previous results, some stabilization was observed once learners reached a certain proficiency level, but this stabilization was dependent on task type. Closed tasks lead to a ceiling effect in some measures, whereas more open tasks give learners from various proficiency levels opportunities to demonstrate their L2 English speaking skills.
Although conditional cash transfers are a cornerstone of Latin American welfare states, little is known about the public opinion dynamics that sustain or challenge their long-term viability. Drawing on original, nationally representative surveys conducted in 2022 in seven Latin American democracies (Argentina, Chile, Colombia, Costa Rica, Guatemala, Mexico, and Peru), this article examines public support for cash transfers toward children across three dimensions: existence (yes/no), breadth (who should receive them) and adequacy (benefit levels). Across all countries, we find widespread support for such transfers, challenging the notion that only universal policies can create broad social support. However, preferences for expansion vary significantly across countries, with only partial alignment with existing coverage: support is highest in countries with extensive and minimal program coverage. Logistic regression models reveal that gender and household composition (living with children and being of reproductive age) are strong predictors of individual preferences, in addition to ideology and income. These findings contribute to existing scholarship by highlighting the role of gender and household composition in shaping social policy preferences.
This paper explores how unrecognised separatist entities in Eurasia – de facto regimes such as Transnistria, South Ossetia, Abkhazia, Nagorno-Karabakh, and the Donetsk and Luhansk People’s Republics – engage with international law. It examines whether, and to what extent, these regimes comply with international law, analysing court decisions and legislation to move beyond simplistic views of non-recognition or assumed legality. The findings reveal that de facto regimes tend to mirror the international law approaches of the states they are most closely connected to – whether the territorial state (e.g. Ukraine) or an outside state exercising effective control over the entity (e.g. Russia or Armenia). This pattern is explained by the theory of “acculturation to statehood”: through sustained legal and institutional interaction, these regimes internalise and replicate the legal systems of their reference states. The study contributes to a more nuanced understanding of the role of de facto regimes in the international legal order.
Free community pet clinics (FCPCs) are instrumental in providing healthcare services for pets in resource-constrained communities. These programmes are typically single-day and coupled with limited opportunity for post-operative follow-up, the likelihood of compromise on the welfare of the sterilised pets becomes apparent. The objective of this study was to identify welfare and ethical challenges associated with dog sterilisation clinics conducted in Kampala Metropolitan Area, Uganda, from May to October 2023. We evaluated the welfare of 46 dogs sterilised at the FCPCs. We collected data using a questionnaire combined with observations and checklists at all stages, including arrival, pre-surgical evaluation, post-surgical recovery, and follow-ups at 7 and 30 days post-surgery. Dogs transported to the clinics by motorcycle moved the longest distance (9.5 km; range: 7.2–11 km), followed by those brought by car (3.8 km; range 3.8–4 km) and lastly by walking (2.0 km; 1–3 km). During the pre-surgical waiting period and post-surgical recovery, 91.3 and 63.0% of dogs, respectively, did not receive any provisions. The Animal Welfare Assessment Grid (AWAG) tool evaluated the impact of physical, psychological, and procedural factors on dog welfare and revealed that procedural events had the most negative impact. In the follow-up, one week post-surgery, a significant percentage of dogs were healing normally (73.7%) while infection at the surgical site was reported in 15.4%. Assessing the behavioural change of dogs by 30 days post-operatively, 46.4% reportedly had increased aggression levels. These findings highlight crucial welfare and stress control points for dogs sterilised at free community clinics, which may influence the outcome of the surgery and later interactions with healthcare professionals.
We prove that the spectrum of Van Douwen families is closed under singular limits. For any maximal eventually different family Raghavan defined in [10] an associated ideal which measures how far the family is from being Van Douwen. Under CH we prove that every ideal containing $\mathrm {Fin}$ is realized as the associated ideal of some maximal eventually different family. Finally, we construct maximal eventually different families with Sacks-indestructible associated ideals to prove that in the iterated Sacks-model every $\aleph _1$-generated ideal containing $\text {Fin}$ is realized.
As democratic institutions around the world confront rising authoritarian pressures, the imperative to understand when and how citizens justify illiberal governance has increased. This study investigates how ideological orientations condition the relationship between populist attitudes and public support for martial law, drawing on the unprecedented 2024 declaration of martial law in South Korea as a focal case. Using original, nationally representative survey data, we find that populist attitudes do not uniformly predict support for martial law; rather, their influence is fundamentally shaped by respondents’ ideological leanings. Among citizens with strong populist orientations, those on the ideological right exhibit a significantly greater propensity to endorse martial law, whereas their counterparts on the left display pronounced resistance to such authoritarian measures. These findings highlight the ideologically contingent nature of populist attitudes and show how populism can serve to either legitimize or challenge authoritarianism, depending on individuals’ ideological orientations.