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The Drittwirkung determined the discussion on the impact of fundamental rights on private relations, significantly influencing the dogmatics of fundamental rights and the paradigm of their application in Germany. The current state of development of the Drittwirkung is a result of a dialogue over the course of several decades in German academia between the Federal Constitutional Court and legal scholars, who point out the dogmatic deficiencies of this concept. The development of the problem of the phenomenon in question in the jurisprudence of the FCC progressed along two lines. Firstly, it consisted of the dogmatization of the Drittwirkung, as this is how the process of the clarification of the conditions for the radiating impact of fundamental rights can be described in its subsequent rulings. Secondly, the efforts of the FCC were aimed at searching for solutions alternative to Drittwirkung, which could justify the horizontal application of fundamental rights norms. The article reconstructs the dogmatization process of Drittwirkung with reference to the key rulings in the development of this concept. It presents a possible account of the relationship between Drittwirkung and Schutzpflichten. Finally, it argues in favour of a reorientation of the doctrine of the Drittwirkung, framing the horizontal application of fundamental rights as an interpretation in accordance with the constitution.
We examined how language affects moral judgments in a non-WEIRD population. Tanzanian participants (N = 103) evaluated utilitarian agents in moral dilemmas, either in native Chagga or foreign Swahili. Agents were rated significantly more moral and braver when evaluated in a foreign language. Bravery predicted morality more strongly in the foreign language than in the native language. Indirect sacrifices were judged more moral than direct ones, but equally brave. These findings extend the moral foreign language effect to informally acquired languages and highlight methodological implications for cross-cultural research.
Psychomotor disturbance has long been observed in major depressive disorder (MDD) and is thought to be a key indicator of illness course. However, dominant methods of measuring psychomotor disturbance, via self-report and clinician ratings, often lack objectivity and may be less sensitive to subtle psychomotor disturbances. Furthermore, the neural mechanisms of psychomotor disturbance in MDD remain unclear.
Methods
To address these gaps, we measured psychomotor agitation via a force variability paradigm and collected resting fMRI in 47 individuals with current MDD (cMDD) and 93 individuals with remitted MDD (rMDD). We then characterized whether resting-state cortico-cortical and cortico-subcortical connectivity related to force variability and depressive symptoms.
Results
Behaviorally, individuals with cMDD exhibited greater force variability than rMDD individuals (t(138) = 3.01, p = 0.003, Cohen’s d = 0.25). Furthermore, greater force variability was associated with less visuomotor connectivity (r(130) = −0.23, p = 0.009, 95% CI [−0.38, −0.06]). Visuomotor connectivity was significantly reduced in cMDD relative to rMDD (t(130) = −2.77, p = 0.006, Cohen’s d = −0.24) and mediated the group difference in force variability (ACME β = −0.06, 95% CI [−0.16, −0.01], p = 0.04).
Conclusions
Our findings represent a crucial step toward clarifying the pathophysiology of psychomotor agitation in MDD. Specifically, altered visuomotor functional connectivity emerged as a candidate neural mechanism, highlighting a promising direction for future research on dysfunctional visually guided movements in MDD.
Key to the success of international peace-building efforts is the cooperation and support of civilian populations. Studies show that economic considerations shape combatants’ willingness to lay down their arms. We study a related but under-studied question: does economic hardship impact civilian support for conflict cessation? If reintegration of former combatants into productive economic sectors threatens civilians’ own incomes, then support for peace-building may diminish. We investigate localized effects of the 2015 Hindu Kush earthquake using individual-level survey data on support for Taliban reintegration. The earthquake reduced support for reintegration into disproportionately impacted economic sectors. We observe no effect for less impacted sectors. Results are robust to a battery of tests, including a novel spatial randomization leveraging geocoded fault lines corresponding to the universe of counterfactual earthquakes. Our findings provide new insight into the resolution of violent conflict: economic hardship may undermine civilian support for rebel reintegration.
We describe the main insights from the papers included in this special issue, Challenges for the Development of Latin America in the Anthropocene: Current Research in Environmental Economics. The contributions are organized around three themes: the economic and welfare impacts of temperature variability, the role of institutions and user rights in shaping environmental governance and the effectiveness of regulatory instruments for managing ambient and atmospheric pollution. Together, these papers show that environmental outcomes in Latin America are deeply shaped by institutional capacity, governance quality and social inequality. By combining rigorous empirical analysis with attention to local contexts, they demonstrate how environmental economics can inform policy responses to the triple planetary crisis of climate change, biodiversity loss and pollution.
Ireland’s historical coordinates are shifting, prompting a re-examination of national narratives and of the assumptions and anxieties that have kept them in place. Increasingly, stories that disturb rather than coalesce with grand narratives are the focus of historical study, revealing the structural violence used to maintain societal order. This article argues that tending to bigger questions about power and smaller ones about human experience creates space for new and diverse histories. It explores the dynamics that shaped the grand narratives central to Irish history and proposes the idea of imagined and lived encounters as a way of thinking about differentiation, the relational nature of power and its impact on experience and everyday life. An analysis of the concept of respectability is used to probe how power functions. The article concludes with a consideration of the historical archive broadly defined, highlighting the benefits of embracing the ‘unreliable’ witness, listening and accounting for silences, touching the material, and considering imagination as a force constantly at play in the encounters that shape history. The acceptance of this dynamic instability in historical research creates possibilities for new voices and perspectives to emerge.
The Ordovician Puna retroarc foreland basin in northwestern Argentina accommodated the c. 3500 m thick Puna Turbidite Complex, consisting of the Lower and Upper Turbidite systems. The turbidites accumulated in the Middle Ordovician over 15 Myr. 744 new detrital zircon U-Pb ages obtained from seven medium and fine-sand turbidite layers of the Puna Turbidite Complex reflect a South American provenance from the Terra Amazonica and the early Terra Australis orogens between 2000 Ma and 440 Ma. The most abundant detrital zircon age group consists of Ordovician ages representing the Famatinian orogenic cycle (520–410 Ma), followed by those of the preceding Olmos-Pampean orogenic cycle (650–520 Ma), the Neoproterozoic rifting phase connected to Rodinia dispersal (1000–650 Ma) and the Sunsás orogenic cycle (1200–1000 Ma). The age distributions of fine and medium sand turbidite layers are statistically almost identical and do not display significant effects of sorting. Subchondritic ϵHf(t) values of Ordovician zircon emphasise crustal recycling and reworking as the most significant processes during the Famatinian Orogenic cycle. Hf(TDM2) indicates that crustal material mostly formed as juvenile crust in Mesoproterozoic time, during the Rȏndonia-San Ignacio and Sunsás orogenic cycles. Detrital zircon δ18O data obtained from syndepositional Ordovician zircon are elevated and range between 6.5 and 8.8 ‰. Combined with similar data from the literature on intrusive and orthometamorphic rocks of the Famatinian magmatic arc, these data indicate that crustal recycling and reworking of supracrustal rocks played a major role in the evolution of the Famatinian arc in the southern central Andes.
Between December 2018 and August 2019, political activities in Sudan resulted in the overthrow of the incumbent regime. Despite efforts by the security apparatus to retain control, continued mobilization of Sudanese working peoples ensured civilian participation in the transitional government. How did the organization of Sudanese working peoples lead to the overthrow of the regime and challenge the state? Drawing on the work of Global African thinkers, and analyzing organizational documents, systematically collected media reports on the uprising (2018–2019), and insights from ethnographic fieldwork in Khartoum (2022), I argue that the nonhierarchical coordination of autonomous, self-organized groups - such as the Neighborhood Resistance Committees and Tea Sellers Association - representing different sections of the working poeples was central to the movement’s success. These findings enrich our understanding of the Sudanese revolutionary process by showing how coordinated self-organization served as an asset for political change.
Impressionist painting was the dominant art form of its time, and one to which English-speaking poets were profoundly responsive. Yet the relationship between impressionism and poetry has largely been overlooked by literary critics. After Impressionism rectifies this oversight by offering the first extended account of impressionism's transformative impact on anglophone verse. Through close readings of the creative and critical writings of Arthur Symons, W. B. Yeats, Ford Madox Ford, the Forgotten School of 1909 and Ezra Pound, it argues that important ideas in the history of modern poetry-ideas such as decadence, symbolism, vers libre and imagism-were formulated as expressions of (or sometimes as antidotes to) impressionist aesthetics. In doing so, it suggests that impressionism was one of the crucial terms-often the crucial term-through and against which English verse of the late nineteenth and early twentieth centuries was defined. This title is also available as open access on Cambridge Core.
In many African countries, limited population data pose a challenge for tax administrations struggling with informal economies. This study examines Uganda’s integration of national ID data into tax registration through “Instant TIN,” an interface linking the Uganda Revenue Authority (URA) with the National Identification and Registration Agency (NIRA) and the Uganda Registration Service Bureau (URSB). This reform aims to streamline taxpayer registration and improve data quality. Using a mixed-methods approach—combining interviews with government officials and administrative data analysis—we identify three key findings. First, Instant TIN registrants differ significantly from those using the conventional process. They are more likely to be individuals, female, younger, and previously informal, highlighting the reform’s role in bringing in marginalised taxpayers. Second, Instant TIN improves data quality. It reduces TIN duplications for individuals and enhances contact accuracy, decreasing invalid or missing email addresses by eight percentage points and invalid phone numbers by six. However, it worsens sector data quality, increasing missing or incorrect sector information by 12 percentage points. Third, while Instant TIN reduces duplication, manual data entry, and administrative burdens, challenges remain. Infrequent updates in external datasets and a lack of validation within the interface increase administrative costs and complicate taxpayer engagement. Additionally, mandatory in-person updates and invalid contact details add to compliance burdens. Overall, Uganda’s experience highlights both the potential and limitations of integrating national ID data for tax administration, offering insights for other countries considering similar reforms.
Concern for Pseudomonas aeruginosa in diabetic foot infections (DFIs) is common and a driving factor for empiric antibiotic prescribing, particularly among immunocompromised hosts. This study sought to identify the prevalence of Pseudomonas aeruginosa in DFIs among kidney transplant recipients and the use of antipseudomonal agents for empiric antibiotic coverage.
Design:
Retrospective cohort study.
Setting:
Large, urban, tertiary care transplant center.
Patients:
39 kidney transplant recipients who developed DFIs at our institution between 2015–2023.
Methods:
We performed a retrospective review of 47 DFIs in 39 kidney transplant recipients hospitalized for a DFI with a positive tissue culture.
Results:
A total of 79 organisms were isolated. Pseudomonas represented 6.33% of organisms (5/79) and was present in 5/47 DFIs (10.6%). Staphylococcus aureus was the most commonly isolated organism (30.4%, 24/79). Compared to those with non-Pseudomonas infections, patients with cultures positive for Pseudomonas were temporally closer to transplant (50.6 days +/- 214.9 vs 1047.6 days +/- 766.4, p = 0.041) and more likely to have been treated for rejection with the past 12 months (2/5, 40% vs 0/42, 0%, p = 0.009). Eighty three percent of patients received empiric antibiotic coverage with an antipseudomonal agent.
Conclusions:
Our study found a low overall prevalence of Pseudomonas in DFIs among kidney transplant recipients. Despite this, empiric coverage with antipseudomonal antibiotics was common, highlighting a potential antimicrobial stewardship target in solid organ transplantation.
How can we make global sensitivity analysis accessible and viable for engineering practice? In this translation article, we present a methodology to enable sensitivity analysis for structural and geotechnical engineering for built environment design and assessment workflows. Our technique wraps computational mechanics and geomechanics finite element (FE) simulations and combines high-performance computing on public cloud with surrogate modeling using machine learning. A key question we address is: “Is there a noticeable loss in fidelity of results from the sensitivity analysis when substituting a simulation model with a surrogate model?” We answer this question for both linear and nonlinear FE simulations.
We investigate the synchronization of speech and co-speech actions (i.e., manual game moves) in a dyadic game interaction across different levels of information structure and mutual visibility. We analyze cross-modal synchronization as the temporal distance between co-speech actions and corresponding (1) pitch accent peaks and (2) word onsets. For (1), we find no effect of mutual visibility on cross-modal synchronization. However, pitch accent peaks and co-speech actions are more tightly aligned when game moves are prosodically prominent due to information structural needs. This result is in line with a view of a tightly coupled processing of modalities, where prominence-lending modifications in the prosodic structure attract corresponding manual actions to be realized in a way similar to ‘beat’ gestures. For (2), we do find an effect of mutual visibility, under which co-speech actions are produced earlier and more tightly aligned with word onsets. This result is in line with a view in which co-speech actions act as communicative affordances, which may help an early disambiguation of a message, similar to ‘representational’ co-speech gestures.
Mars, one of the most Earth-like celestial bodies in the Solar System, is a key focus in the search for extraterrestrial life. However, pure liquid water – essential for life as we know it – is unstable on its surface today due to low pressure and frigid conditions. Concentrated salt solutions (brines) may form through the deliquescence of hygroscopic salts like chlorates and perchlorates detected on Mars, offering a potential water source for hypothetical halotolerant organisms due to the brines’ lower freezing point and reduced vapour pressure. This study simulates brine formation on Mars using a methodical setup. Martian global regolith simulant MGS-1 was either supplemented with hygroscopic salts such as sodium chloride (NaCl), sodium chlorate (NaClO3), sodium perchlorate (NaClO4) or used without the addition of salts as a control. Samples were inoculated with the halotolerant yeast Debaryomyces hansenii, chosen for its high (per)chlorate tolerance. Desiccated samples were transferred to an environment with constant relative humidity (98%), allowing the salts to absorb water from the atmosphere through deliquescence. The study examined the survival of D. hansenii after desiccation and its ability to grow using water absorbed through deliquescence. The results revealed that D. hansenii survived the desiccation in samples containing NaClO3, NaCl or no additional salt and grew in the control samples as well as in the deliquescent-driven NaClO3 and NaCl brines. No survival was observed in samples containing NaClO4 after the desiccation step. These findings suggest that Mars could potentially harbour life in specific niches where deliquescent brines form, specifically in NaCl or NaClO3 rich areas. NaClO4, at least for the yeast tested in this study, is too toxic to support survival or growth in deliquescene-driven habitats.
Taiwan is regarded as the vanguard of LGBT+ rights in Asia. We conducted a scoping review to map research on LGBT+ inclusion in Taiwan, identify knowledge gaps and propose future directions for research and policy. Results indicate a predominant focus on health, with the over-representation of gay men and exclusion of lesbian and bisexual women and transgender/gender diverse people. Despite being the first Asian jurisdiction to legalise same-sex marriage, insufficient policy protections were evidenced concerning family formation, adoption, and parenting, with family systems that largely exclude LGBT+ people. Findings reveal pervasive discrimination and exclusion in education, an economic system that restricts LGBT+ people’s employment opportunities and advancement, and a healthcare system that lacks competencies in serving LGBT+ people. Future research on LGBT+ inclusion in Taiwan should address understudied populations, provide disaggregated data on LGBT+ individuals, and advance evidence to support policy protections in education, economic, family, health, and political domains.
The colonial ascidian Didemnum vexillum (Carpet Sea Squirt) is globally established as a non-native species with diverse negative impacts. A second Didemnum species, D. pseudovexillum, was described in 2020, living alongside D. vexillum and virtually indistinguishable from it in external appearance. It is not known whether this second species has environmental and economic impacts similar to those of D. vexillum, nor whether it should be regarded as native or non-native in Europe. Early records were from four sites, all in or adjacent to marinas, in north-west France, the Mediterranean coast of Spain and the east coast of Italy. Here, an occurrence of D. pseudovexillum in a seagrass bed in south-west England is reported, identified by both sequencing of the cytochrome c oxidase subunit 1 gene (COI) and examination of internal morphology. Separate studies collected and identified specimens of D. vexillum/pseudovexillum from 11 marinas on the English and Welsh coasts, and D. pseudovexillum was not found amongst these. Only two pre-2020 didemnid COI sequences now referrable to D. pseudovexillum have been found in the BOLD System and GenBank databases (these records being from Mediterranean Spain in 2013); this suggests that the species is a relatively recent addition to the European fauna from an unrecognized existing range.
In 1976, Cameron, Goethals, Seidel, and Shult classified all the graphs whose smallest eigenvalue is at least $-2$ by relating such graphs to root systems that appear in the classification of semisimple Lie algebras. In this paper, extending their beautiful theorem, we give a complete classification of all connected graphs whose smallest eigenvalue lies in $(\! -\lambda ^*, -2)$, where $\lambda ^* = ho ^{1/2} + ho ^{-1/2} \approx 2.01980$, and $ho$ is the unique real root of $x^3 = x + 1$. Our result is the first classification of infinitely many connected graphs with their smallest eigenvalue in $(\! -\lambda , -2)$ for any constant $\lambda \gt 2$.
Geographical indications (GIs) are information signals based on a product’s geographical origin. They reduce information asymmetry for consumers and protect producers from imitation. This paper examines the local economic impact of GIs by focusing on the renowned Champagne AOC in France. Champagne is protected under the Appellation d’Origine Contrôlée (AOC), the EU’s strongest GI classification. My identification strategy leverages the fact that the municipal-level boundary of the Champagne AOC was historically determined by political decisions, rather than viticultural qualities (i.e., terroir). Using granular geographic, economic, and fiscal data, I provide causal evidence that this institutional protection improves local economic outcomes beyond the wine sector. Despite a sharp increase in vineyard prices over the past two decades, there is no evidence of crowding out of other economic activity over time. These findings suggest that the projected expansion of the Champagne AOC could stimulate further regional economic development for newly admitted municipalities.
Let F be a totally real field. Let $\mathsf {A}$ be a simple modular self-dual abelian variety defined over F. We study the growth of the corank of Selmer groups of $\mathsf {A}$ over $\mathbb {Z}_p$-extensions of a complex multiplication (CM) extension of F. We propose an extension of Mazur’s growth number conjecture for elliptic curves to this new setting. We provide evidence supporting an affirmative answer by studying special cases of this problem, generalising previous results on elliptic curves and imaginary quadratic fields.
The study of Ordovician ostracods from eastern North America has been neglected for more than 40 years, prompting the need for taxonomic updates. Newly acquired silicified materials from the Late Ordovician Crown Point Formation of Valcour Island, northeastern New York State, are here systematically described. Fifty-two species of 42 genera are identified, including three new species: Vogdesella longidorsa n. sp., Eokloedenella duodepressa n. sp. and Aviacypris valcourensis n. sp. The combination of high diversity and dominance of both beyrichiocopids and podocopids indicates that the Valcour fauna existed in a stable, shallow-water carbonate environment. Biostratigraphical evidence supports an early Sandbian age designation for the Crown Point Formation. Comparison of the Valcour fauna with others in Laurentia as well as from adjacent paleocontinents shows shared composition at the genus level, especially with Baltica, but high endemicity at the species level. This suggests a history of frequent faunal exchange with a fast speciation rate during the early Late Ordovician in the southern region of Laurentia.