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Doubly diffusive convection describes the fluid motion driven by the competing buoyancy forces generated by temperature and salinity gradients. While the resulting convective motions usually occupy the entire domain, parameter regions exist where the convection is spatially localised. Although well studied in planar geometries, spatially localised doubly diffusive convection has never been investigated in a spherical shell, a geometry of relevance to astrophysics. In this paper, numerical simulation is used to compute spatially localised solutions of doubly diffusive convection in an axisymmetric spherical shell. Several families of spatially localised solutions, named using variants of the word convecton, are found and their bifurcation diagram computed. The various convectons are distinguished by their symmetry and by whether they are localised at the poles or at the equator. We find that, because the convection rolls that develop in the spherical shell are not straight but curve around the inner sphere, their strength varies with latitude, making the system prone to spatial modulation. As a consequence, spatially periodic states do not form from primary bifurcations and localised states are forced to arise via imperfect bifurcations. While the direct relevance of this work is to doubly diffusive convection, parallels drawn with the Swift–Hohenberg equation suggest a wide applicability to other pattern-forming systems in similar geometries.
This article examines the national and international context within which Colombian immigration policy developed in the mid-twentieth century. Focussing on Republican refugees from the Spanish Civil War, it traces how and why policymakers and public opinion began to see these groups as potentially harmful to society. It argues that Colombian immigration policy emerged at the intersection of multiple, evolving discourses of race which both helped frame and were shaped by anxieties over a mass influx from Spain. By exploring the stories of several Republicans who tried to come to Colombia, the article also reveals how they helped shape immigration policy.
This study examines the interplay between welfare stigma and need in the decision to claim social welfare benefits in Hong Kong, a liberal welfare city where self-reliance and family obligations are highly valued. Our interviews with seventeen low-income parents, suggest that first, their availability and ability to work influence their self-perceived ‘deservingness’ of aid. This, in turn, affects their anticipated self-stigma and their assessment of needs. Second, having children influences parents’ decisions to claim social welfare benefits through both anticipated stigma and childcare needs. Finally, low-income parents are trapped in an impossible triangle of being a ‘good’ parent, caught between fulfilling parental responsibilities, providing for their children financially, and modeling self-reliance to protect them from welfare stigma. Claiming benefits fulfills the first two but sacrifices self-reliance, while choosing not to claim fulfills the latter two but sacrifices parental responsibilities. Both choices carry emotional consequences that can undermine parent-child relationships.
The Taiwan Incident of 1874 – a prolonged Sino-Japanese confrontation over the killing of Ryukyu castaways, whom Japan claimed as its subjects – marked the full maturation of a new mode of Qing war preparation. This mode was characterized by global coordination, domestic and international competition, and the swift mobilization of personal connections to secure foreign weapons and loans – resources that were often interconnected. Facilitated by the efforts of various actors, this internationalized approach became a standard practice during the empire’s final decades. As the empire could no longer rely on domestic self-sufficiency in arms and funding, Qing military operations came to reflect the broader influence of global military and financial resources. The Qing empire’s capacity to mobilize global resources in pursuit of national objectives helps explain its resilience in an era dominated by imperial powers.
Holocene environmental changes on the Paraty coastal plain in southeastern Brazil unfolded under dynamic sea-level fluctuations and shifting sedimentary regimes. Continental and marine palynomorph analyses, combined with calibrated radiocarbon dating from two sediment cores (JBS1 and JBS2), reveal a continuous depositional record spanning approximately 7800 to 1000 cal yr BP. Sandy mud and muddy sand sequences reflect variable coastal energy conditions through out the mid to late Holocene. Dinoflagellate cyst assemblages indicate a transition from open marine to marginal marine environments, with maximum marine influence between 7000 and 5000 cal yr BP. Terrestrial palynomorphs show a concurrent shift from grassland-dominated landscapes to mixed vegetation including ombrophilous forest taxa. A marked increase in pollen concentration in the upper stratigraphic layer suggests coastal progradation, enhanced continental input, and reduced marine influence during the late Holocene regression. Bayesian age-depth models demonstrate uninterrupted but variable sedimentation rates, with no evidence for erosional surfaces or depositional hiatuses. The results align with regional sea-level reconstructions and under score the role of transgressive-regressive processes and delta infilling in shaping vegetation dynamics. This integrated micropalaeontological and chronostratigraphic approach offers a robust framework for interpreting Holocene palaeoenvironmental evolution in tropical coastal settings.
Pseudoaneurysm after valve-sparing aortic root replacement is uncommon but potentially life-threatening. We report an unusual case of spontaneous resolution of an aortic root pseudoaneurysm that developed in a 14-year-old boy with Marfan syndrome following valve-sparing aortic root replacement. This case suggests that, in carefully selected situations, non-surgical management with intensive follow-up may be beneficial.
In Jishishan County, Linxia Prefecture, Gansu Province, China, the altitude ranges from 1,787 meters to 4,308 meters. At 23:59 Beijing time on December 18, 2023, a magnitude 6.2 earthquake struck Jishishan County. The objective is to report the injury characteristics and medical treatments of those injured in the earthquake.
Methods:
The injury and treatment data were retrospectively collected and analyzed for earthquake-related injuries among patients admitted to the People’s Hospital of Linxia Hui Autonomous Prefecture and the Traditional Chinese Medicine Hospital of Linxia Hui Autonomous Prefecture.
Observations:
A total of 166 patients were hospitalized: 142 at the People’s Hospital of Linxia Hui Autonomous Prefecture and 24 at the Traditional Chinese Medicine Hospital of Linxia Hui Autonomous Prefecture. Among the injured, 40.3% presented with a single injury. The others had multiple injuries: 28.3% had two injuries, 14.5% had three injuries, 12.1% had four injuries, 4.2% presented with five injuries, while only 0.6% were diagnosed with six injuries. Additionally, 78.9% involved fractures alone, 36.8% involved lung contusions, and 34.9% involved both fractures and lung contusions. Conservative treatment was used slightly more than surgery (54.8% versus 45.2%). Among the 75 surgical cases, internal fixation and sutures were the most common (17.4% each). In total, 53.0% of the injured were treated and discharged and 47.0% were transferred to provincial hospitals. In addition, the outcome of injured patients with differing injury conditions was different.
Analysis:
Fractures and multiple injuries were the primary injury types in this study. Suturing and internal fixation were the most common surgical interventions. The core findings of this study provide an important reference for regionalized prevention and treatment of rural earthquake injuries in high-altitude regions.
Un oficial del ejército chileno relata que en 1879 los atacameños (o Lickanantay; actuales comunidades indígenas del interior de la región de Antofagasta, norte de Chile) realizaban procesiones al volcán Licancabur todos los años. Contrastando este relato, nos propusimos investigar el camino de peregrinación que utilizaban desde el pueblo de San Pedro de Atacama hasta dicho centro ceremonial. Entregamos aquí los resultados iniciales de esta investigación y evaluamos la profundidad cronológica de las peregrinaciones a las altas montañas, las que hasta ahora se han considerado una práctica originada con el estado Inka (ca. 500 aP), como el caso del rito de la Capacocha. Si bien nuestros datos son preliminares, son concluyentes en mostrar que las prácticas peregrinas andinas a las montañas son milenarias y que se desarrollaron desde hace unos 3.300 años, continuando hasta fines del siglo diecinueve en el caso del Licancabur. En la actualidad, sin embargo, no hemos logrado dar con ningún registro ni memoria oral que dé cuenta de procesiones desde los oasis sanpedrinos al volcán, develando una notable amnesia histórica colectiva, provocada en gran parte por la reciente delimitación de las fronteras estados-nacionales después de la Guerra del Pacífico.
Accurately modelling wind turbine wakes is essential for optimising wind farm performance but remains a persistent challenge. While the dynamic wake meandering (DWM) model captures unsteady wake behaviour, it suffers from near-wake inaccuracies due to empirical closures. We propose a symbolic regression-enhanced DWM (SRDWM) framework that achieves equation-level closure by embedding symbolic expressions for volumetric forcing and boundary terms explicitly into governing equations. These physically consistent expressions are discovered from large-eddy simulations (LES) data using symbolic regression guided by a hierarchical, domain-informed decomposition strategy. A revised wake-added turbulence formulation is further introduced to enhance turbulence intensity predictions. Extensive verification across varying inflows shows that SRDWM accurately reproduces both mean wake characteristics and turbulent dynamics, achieving full spatiotemporal resolution with over three orders of magnitude speed-up compared to LES. The results highlight symbolic regression as a bridge between data and physics, enabling interpretable and generalisable modelling.
Individuals with mental health difficulties (MHD) have a substantial reduction in life expectancy compared to the general population. It is increasingly recognised that mental health services need to improve physical healthcare as a priority. Sexual health, including consideration of high-risk sexual behaviours, medication side effects, and challenges in romantic relationships, is a further important but under-recognised aspect of overall health. We discuss some of the current issues relating to physical and sexual health, with a particular focus on youth with MHD and how we might implement holistic care in Ireland. Prioritising the resourcing of these issues could facilitate the implementation of a Shared Model of Care as recommended in Ireland’s National Mental Health Policy, Sharing the Vision.
This study aimed to evaluate the impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and inactivated virus vaccination on intracytoplasmic sperm injection (ICSI) outcomes in infertile couples. A retrospective case–control study was conducted at the Royan Institute from August 2020 to March 2022. The study included 90 couples in the COVID-19 infection phase and 31 in the vaccination phase. A total of 30 infected but unvaccinated couples were compared to a control group of 60 couples with no COVID-19 infection or vaccination history. Additionally, 31 couples underwent treatment before and after receiving the Sinopharm inactivated vaccine. Key variables analysed included sperm parameters (concentration, motility, progressive motility and morphology), ovarian parameters (antral follicle count, oocyte retrieval), embryological outcomes and pregnancy outcomes. SARS-CoV-2 infection significantly reduced sperm motility (P = 0.02) and progressive motility (P = 0.01) compared to controls. Sperm concentration and morphology showed non-significant declines. Post-vaccination analysis revealed similar but statistically insignificant changes in sperm parameters. Ovarian stimulation parameters and embryological outcomes remained unaffected by both infection and vaccination. Although biochemical, clinical pregnancy and live birth rates were lower among the infected group, these differences did not reach statistical significance (p = 0.16, 0.08 and 0.09). SARS-CoV-2 infection has been associated with impaired sperm progressive motility, which may negatively influence ICSI outcomes. In contrast, vaccination with an inactivated virus does not appear to impact fertility outcomes. These findings provide crucial guidance for physicians and infertile couples managing treatments during and after the pandemic, suggesting the need for extended recovery periods before ART procedures following COVID-19 infection.
Deterministic and stochastic processes are of great importance in influencing the composition of communities. Here, we tested if deterministic and stochastic processes have the same force of influence on functional traits of tiger moth communities. Specifically, we hypothesised that the functional traits of the tribe Arctiini would be more strongly influenced by stochastic processes (associated with spatial variables), given that these moths are primarily diet and habitat generalists within a highly diverse clade. They also exhibit high morphological trait dissimilarity and are capable of occupying a wide range of vegetation habitats. On the other hand, we hypothesised that the functional traits of the tribe Lithosiini would be more influenced by deterministic processes (associated with environmental variables), given that these moths are primarily diet and habitat specialist moths and tend to occur in more specific vegetation types. In agreement with our hypotheses, the functional traits of Arctiini species were better explained by variables related to stochasticity, while the functional traits of Lithosiini were explained by deterministic processes only. Thus, the processes shaping moth distributions across communities may vary according to species’ functional traits and interspecific relationships.
Stroke remains a major public health issue globally. Tele-rehabilitation, incorporating internet-based interventions and wearable devices, offers an accessible strategy for post-discharge rehabilitation. This study evaluates their effectiveness in stroke patients.
Methods:
A total of 160 subacute stroke patients hospitalized between November 2022 and September 2023 were enrolled and randomly allocated to four groups at discharge (n = 40 per group): a control group receiving conventional rehabilitation, an internet-based tele-rehabilitation (ITR) group, a wearable-device-assisted (WDA) group and a combined intervention (IWT) group, which received both ITR and WDA training. The primary outcome was assessed by the Modified Barthel Index (MBI) at discharge, 4 weeks and 12 weeks post-discharge, with the 12-week score prespecified as the primary endpoint. Secondary outcomes included Berg Balance Scale (BBS), simplified Fugl-Meyer Assessment (sFMA), Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD), Mini-Mental State Examination (MMSE) and Zarit Burden Interview (ZBI), all assessed at discharge, 4 weeks and 12 weeks post-discharge.
Results:
At baseline, no significant differences were observed among groups (P > 0.05). Over 12 weeks, all intervention groups demonstrated significant improvements in MBI, BBS and sFMA compared to the control group (P < 0.05), with the IWT group achieving the greatest gains (P < 0.01). Anxiety, depression and caregiver burden significantly decreased across intervention groups, with the IWT group showing the most pronounced reductions (P < 0.01). Cognitive function also improved significantly, particularly in the IWT group (P < 0.01).
Conclusion:
ITR and WDA training enhances functional and psychological recovery in stroke patients, highlighting its potential clinical significance in managing stroke recovery.
In a normal pregnancy, glucocorticoids (GC), such as cortisol, play an essential role in early heart development. GC concentrations surge in late gestation to facilitate the maturation of fetal systems in preparation for birth. However, pregnancy complications related to stress, lifestyle factors, disease, and commonly used antenatal care treatments (GC therapy and artificial reproductive technology) can lead to prematurely increased GC concentrations that are detrimental to the heart before it is mature enough to benefit. These findings underpin the hypothesis that GC play a double-edged role that benefits normal heart development but is potentially harmful when dysregulated. However, the mechanisms by which both physiological and pathological elevations in GC concentrations influence the fetal cardiometabolic pathways that lead to detrimental long-term cardiovascular outcomes remain unclear. This review will, firstly, describe how cortisol regulates different aspects of cardiac development and, secondly, compare findings from different animal models that have provided mechanistic insight into how excess cortisol/GC during pregnancy impacts cardiac health across the life course.