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In this paper, we show that the Day monoidal product generalises in a straightforward way to other algebraic constructions and partial algebraic constructions on categories. This generalisation was motivated by its applications in logic, for example, in hybrid and separation logic. We use the description of the Day monoidal product using profunctors to show that the definition generalises to an extension of an arbitrary algebraic structure on a category to a pseudo-algebraic structure on a functor category. We provide two further extensions. First, we consider the case where some of the operations on the category are partial, and second, we show that the resulting operations on the functor category have adjoints (they are residuated).
The objective of this special issue is to present innovative research demonstrating that prosody needs to be reconceptualized as an inherently multimodal phenomenon, manifested across the spoken and/or visual domains. The studies included are organized into three core themes. Theme 1 addresses the temporal alignment of spoken and visual aspects of prosody, and how this is shaped by linguistic factors, speaker-specific traits (such as neurodiversity) and language learning patterns. Theme 2 deals with the coordination of spoken and visual aspects of prosody in conveying pragmatic intent, focusing on aspects such as negation, emotion and epistemic stance. Theme 3 explores how visual signals, including head movements and manual signals, fulfil essential prosodic roles across diverse sign language typologies. Taken together, the empirical evidence presented here shows that prosody is also embodied and that our bodily movements can manifest prosodic characteristics. On the one hand, they show the need to comprehensively re-evaluate our understanding of how speakers, listeners and learners engage with the prosodic dimension of language. On the other hand, they reveal that non-referential gestures are deeply meaningful and prosodically structured. Ultimately, visual cues are presented as indispensable for building accurate models of the human language capacity.
Bioregenerative life support systems (BLSS) designed to produce food crops in future crewed missions to the Moon or Mars consider in-situ resource utilisation (ISRU). Lunar regolith is, therefore, in focus for future technologies of farming on lunar bases. We tested germination and early growth of broccoli plants (Brassica oleracea var. botrytis italica) in Murashige-Skoog liquid medium with addition of leachate from a lunar regolith simulant. As the additions to growth, differently diluted water and acidic leachates were used. Physiological status of the germinating plants was evaluated by chlorophyll fluorescence parameters related to plant vitality (relative fluorescence decline – Rfd) and photosynthetic performance of photosystem II (1) potential (FV/FM) and (2) effective quantum yield of PSII (ΦPSII), photochemical quenching referring to number of open PSII reaction centres. Both water and acidic leachates inhibited plant growth, however, the extent of growth limitation was dilution-dependent. Full inhibition of germination was apparent when undiluted acidic leachate was added. However, 50% dilution (and higher) resulted in seed germination and the early growth. No negative effects of the water dilutions on FV/FM as well as ΦPSII, were apparent in 15 days old plants, their cotyledonary and the first primary leaves, in particular. Similarly, qP and Rfd showed no sign of either water or acidic leachate addition effect. Although photosystem II-related parameters exhibited no negative effect of the leachates addition, a growth of plants was found dilution-dependent: higher degree of dilution resulted in a more pronounced reduction in plant projection area. In spite of the growth rate reduction (compared to untreated control), properly diluted water and acidic leachates from lunar regolith and/or its simulants might be used in follow up studies focused on plant species prospective for future cultivation in Moon-based stations with temporary or permanent crew.
Adolescence is a sensitive period for social and neural development. Empathic growth during adolescence has been linked to improved prosocial behavior in adulthood. This study examined how adolescent empathy relates to adulthood neural responses to rejection.
Method:
Participants (N = 77; 42 females, 52% White) were drawn from a demographically diverse community sample and assessed annually from ages 13 to 21. Each year, participants’ empathic support provision toward a close friend was evaluated during an observationally coded support task. At approximately age 24, participants completed the Cyberball social exclusion paradigm while undergoing functional magnetic resonance imaging (fMRI).
Results:
Whole-brain exploratory analyses revealed that greater empathic support provision during adolescence was associated with reduced activation in the subgenual anterior cingulate cortex (sACC) during social exclusion in early adulthood (Cohen’s d = 0.12), suggesting a contribution of empathy provision to rejection-related neural responses later in life. The effect was not driven by felt distress during social exclusion, indicating that adolescent empathic support provision is potentially associated with neural responses to social exclusion independent of subjective distress.
Conclusion:
These findings underscore the long-term links of empathy to adult social processes and may inform interventions aimed at enhancing interpersonal functioning and resilience.
Holistic nursing care requires considering not only the physical and psychosocial but also the spiritual care needs of the patient.
Objectives
This study aimed to determine the relationship between nurses’ perceptions of the concept of spiritual care and their attitudes towards death and the care of dying patients.
Methods
The sample of this descriptive and correlational study consisted of 383 nurses. Data were collected using the Spirituality and Spiritual Care Rating Scale (SSCRS), the Spiritual Support Perception Scale (SSPS), the Frommelt Attitude Toward Care of the Dying Scale (FATCOD), and the Death Attitude Profile Scale (DAP-R). The predictive role of nurses’ perceptions of spiritual care on their attitudes toward caregiving for patients approaching death and dying was examined using path analysis. The results of the analysis were presented as descriptive statistics (mean ± SD), and frequency (percentage) distributions. The reliability of the scales and subscales was examined using the Cronbach’s alpha internal consistency coefficient.
Results
The path coefficient between the SSCRS and the DAP-R subscales of Fear of Death (β = 0.232; P = 0.025), Death Avoidance (β = 0.301; P = 0.007), Neutral Acceptance (β = 0.22; P = 0.01), Approach Acceptance (β = 0.444; P < 0.001), and Escape Acceptance (β = 0.659; P < 0.001) was statistically significant. The path coefficient between the FATCOD and the DAP-R subscales of Fear of Death (β = −0.032; P < 0.001), Death Avoidance (β = −0.038; P < 0.001), and Neutral Acceptance (β = 0.02; P < 0.001) was statistically significant.
Significance of Results
It was determined that there was a correlation between the nurses’ perceptions of the concept of spiritual care and their attitudes towards death and the care of dying patients. It can be suggested that the nurses exhibited a more positive attitude toward the care of dying patients as their understanding of spirituality, spiritual support, and spiritual care increased.
High intake of processed foods, especially those with high sodium content, is a contributor to hypertension and cardiovascular disease. This study aimed to compare the sodium content of packaged foods and beverages in Nigeria to WHO Global Sodium Benchmarks and similar products in Kenya and South Africa. The study examined packaged foods from major retail stores in the capital cities of the Federal Capital Territory, Kano, and Ogun states in Nigeria from November 2020 to March 2021. Benchmark values were based on the 2021 WHO Global Sodium Benchmarks. We used secondary data from packaged food surveys conducted in South Africa (2015, 2016 and Kenya 2019). Approximately 40.0% (n = 36) of subcategories of packaged foods were captured in the WHO global sodium benchmark. Of these, 64.0% (n = 23) exceeded the benchmarks, including ‘processed meat’ (912.0 vs. 250.0 mg/100 g), cheese (776.0 vs. 190 mg/100 g), and ‘wholegrain chips’ (930.0 vs. 470 mg/100 g). Exactly 36.0% (n = 13) had lower sodium content, such as ‘rice-based snacks’ (113.0 vs. 520 mg/100 g) and ‘dried seafood’ (400 vs. 800 mg/100 g). In seven out of eleven main food categories (64%), Nigeria had a higher sodium content compared to Kenya. Similarly, Nigeria exhibited higher sodium content than South Africa in six out of eleven food categories (55.0%). With 64.0% of Nigerian subcategories exceeding WHO benchmarks and higher sodium levels than South Africa and Kenya in most categories. These findings highlight the urgent need for targeted sodium reduction and product reformulation to align Nigeria’s packaged foods with international benchmarks.
Effective communication of risks and benefits is essential to ethical clinical trial recruitment, yet clinical research coordinators (CRCs) often lack formal training in how to navigate participant uncertainty. This study examined whether targeted communication training could enhance CRCs’ ability to disclose risks and benefits clearly and ethically.
Approach or Design:
A mixed-methods, pre–post design compared CRCs who received communication training with those in a control group.
Twenty-four CRCs participated across intervention and control groups.
Intervention:
A communication training program grounded, focusing on transparent disclosure, benefit framing, and participant engagement strategies.
Method:
Qualitative content analysis of SP interaction transcripts guided by uncertainty management theory examined risk disclosure, mitigation strategies, benefit framing, and engagement. Frequency analysis tracked changes in the number and specificity of risk/benefit mentions over time.
Results:
CRCs in the intervention group demonstrated more structured and transparent risk disclosure, greater use of participant-centered benefit framing, and improved interpersonal engagement. Frequency analysis showed significant increases in both the number and specificity of risk and benefit mentions post-training. Control group CRCs showed minimal change.
Conclusion:
Targeted communication training enhances CRCs’ ability to manage participant uncertainty, improving both ethical standards and informed consent quality in clinical trial recruitment.
Let G be a simple algebraic group over an algebraically closed field $\Bbbk $ of positive characteristic. We consider the questions of when the tensor product of two simple G-modules is multiplicity free or completely reducible. We develop tools for answering these questions in general, and we use them to provide complete answers for the groups $G = \mathrm {SL}_3(\Bbbk )$ and $G = \mathrm {Sp}_4(\Bbbk )$.
This paper aims to describe what constitutes good-quality, accessible, affordable and acceptable primary care for migrants. This includes identifying system adaptations and offering evidence- and practice-based recommendations and guidance for primary care organizations and professionals on how to deliver such care.
Background:
Migration has significantly diversified European populations. Migrants often face structural, linguistic, cultural, and systemic barriers in accessing appropriate primary care. While these challenges are well-documented, implementation of effective, inclusive care remains inconsistent across countries.
Methods:
This position paper presents a narrative synthesis of existing literature, expert opinions, and recent policy developments. It draws on evidence from healthcare research, policy analyses, and recommendations developed by the European Forum for Primary Care working group on migrants, primarily covering developments from the past decade.
Findings:
High-quality primary care for migrants requires coordinated action across care delivery, capacity building, and system-level structures. Care delivery must be person-centred and comprehensive, supported by interprofessional collaboration and professional interpretation. Capacity building depends on training and education that embed diversity-sensitive care, cultural humility, and structural competency. At the system level, policies should guarantee equitable access, continuity of care, and inclusive quality monitoring, while fostering intersectoral partnerships and community engagement.
Conclusion:
Embedding person-centred, diversity-sensitive, and community-oriented principles into primary care systems is essential for achieving equitable healthcare for migrant populations. This is an urgent plea to healthcare policymakers, organizations, and professionals to undertake action to realise these reforms as they not only improve care for migrants but contribute to stronger, sustainable and more resilient health systems overall.
This essay studies gender in medieval heresy by focusing on an inquisitorial trial in Milan in 1300. The inquisitors investigated a small group of devotees of a deceased penitent woman named Guglielma for venerating her as the Holy Spirit. A noble Humiliati nun, who would become Guglielma’s pope in a coming new age, and a wealthy layman cooperated as the devotees’ leaders. On the surface, the devotees seemed to have reversed gender roles, which late medieval male clergy-female mystic partnerships exemplified. Through an analysis of the surviving records, this article demonstrates that, instead of inverting gender expectations as the inquisitors assumed, the devotees’ vision of a new age – somewhat infused with Joachimism – and the co-leadership of the nun and the layman developed out of transcending the gender binary. As a result, the devotees saw Guglielma not as a co-redeemer with Christ but as the Holy Spirit who comforted them, would convert non-Christians, and had helped unite the devotees, even those of opposing political factions, into a family. Rejecting violent rupture as well as binary gender roles, their future age, which would begin with the nonviolent replacement of the Roman Church, would both preserve Milan’s social hierarchy and eschew binary gender roles.
Transitioning away from fossil fuels is in the best interest for long-term stakeholders of oil firms to mitigate risk from climate policy. Yet firms have an informational and positional advantage over strategies to mitigate climate-related risks, such that there is little incentive to decarbonize. Building on theories of firm behavior and the three faces of political power, we argue that investor pressure will be unlikely to change the climate strategy of fossil fuel firms. To measure climate strategy, we develop a novel technique using natural language processing tools to parse annual filings of all publicly-listed oil firms in the US. Using a difference-in-differences design exploiting an exogenous shock to shareholder power from a Securities and Exchange Commission regulatory amendment, we find no effects of shareholder pressure on deep reforms to climate strategies and weak effects on incremental pro-climate behavior. Through a case study of ExxonMobil, we show that climate-motivated investors are unable to overcome internal stakeholder resistance, despite shareholder pressure through direct communication, filed resolutions, and media campaigns. Our findings illustrate that polluting firms remain resistant to financial pressure for decarbonization, suggesting an important role for policy.
We identify the size of the largest connected component in a subcritical inhomogeneous random graph with a kernel of preferential attachment type. The component is polynomial in the graph size with an explicitly given exponent, which is strictly larger than the exponent for the largest degree in the graph. This is in stark contrast to the behaviour of inhomogeneous random graphs with a kernel of rank one. Our proof uses local approximation by branching random walks going well beyond the weak local limit and novel results on subcritical killed branching random walks.
This paper explores the interplay between intellectual property and gender in modern design law and practice, with a focus on the New Zealand Designs Act 1953 and references to Australian, United Kingdom and European Union law. It highlights how law and practice favour technical, utilitarian design principles (that coded masculine), but neglect the dynamic, sensory and affective (embodied and emotive) aspects of designs (that coded feminine). Through its focus on the technical, design law and practice ignore the socio-legal reality that the dynamic, sensory and affective are often central to a design’s success. The paper frames the foregoing in standpoint theory and affect. It challenges the focus on that which can be reduced to technical-based representation and the perception that this creates an objective master copy. The paper calls for a reassessment of what design law protects and how it protects it, to better align the system with the socio-legal realities of design creation and use.
Apolipoprotein E (APOE), particularly the ϵ4 allele, is a well-established susceptibility gene for dementias. However, its role in other neurological diseases and injuries remains unclear. This study aims to evaluate APOE as a risk factor for nervous system conditions beyond dementias.
Methods:
A systematic review was conducted from inception to May 2025 across six databases: PubMed, Embase, CINAHL, APA PsycInfo, Web of Science and Cochrane. Studies were included if they employed clinical research methodologies, involved adult participants, completed APOE genotyping and examined APOE as a susceptibility gene in nervous system injuries other than dementias.
Results:
Thirty-three studies met inclusion criteria, encompassing stroke (n = 16), traumatic brain injury (n = 11), cranial or peripheral neuropathies (n = 4) and degenerative cervical myelopathy (n = 2). The ϵ4 allele was most consistently associated with increased susceptibility to intracerebral hemorrhage and chronic traumatic encephalopathy. In contrast, no relationship was observed between APOE and cerebral concussion risk. Findings across other conditions including ischemic and hemorrhagic stroke, subarachnoid hemorrhage, post-traumatic seizures, decompressive hemicraniectomy, degenerative cervical myelopathy and peripheral neuropathies were inconsistent or limited by small sample sizes.
Conclusion:
While the APOE genotype may influence susceptibility in intracerebral hemorrhage and chronic traumatic encephalopathy, further research is needed to clarify its broader role and underlying mechanisms in non-dementia nervous system diseases and injuries.
Manes (1998). Implementing Collection Classes with Monads. Mathematical Structures in Computer Science8 (231–276) introduced the notion of a collection monad on the category of sets as a suitable semantics for collection types. The canonical example of collection monad is the finite powerset monad. In order to account for the algorithmic aspects, the category of sets should be replaced with categories whose arrows are maps computable by low-complexity algorithms. Inspired by realizability, we give a systematic way for constructing categories of small sets and low-complexity functions and define an analogue of collection monads on such categories.
Thought reform campaigns aimed at the psychological transformation of captives have long been tools to enhance national security and political legitimacy in East Asia. Fusing Soviet concepts of human perfectibility and Confucian ideals of transformation through education, sophisticated systems have evolved to convert political opponents. Whether labelled as tenkō in Japan, ‘self-renovation’ in Nationalist China, or ‘new learning’ in the People’s Republic of China, these programmes shared the fundamental goal of pressuring individuals to renounce previous beliefs and adopt state-sanctioned ideologies. This article examines how Japanese war crimes prisoners, political dissidents, and former Chinese Nationalist officers experienced these campaigns. Despite differences in implementation, each regime used confession, group study, and psychological coercion. This historical perspective is particularly relevant today as China’s leadership continues to weaponise historical narratives – including the ‘correct’ understandings of WWII history – with implications for contemporary tensions between China and Taiwan.
A despairing agent might object to climate obligations by framing them as too demanding to be morally required because they give rise to burdensome consequences of despair, like depression. This objection can be refuted on the grounds that it is morally wrong. However, when it is understood as symptomatic of moral injury, an alternative response prioritizing moral repair is illuminated. I consider how the virtue of epistemic humility can promote tasks for repair, like attentiveness to symptoms of moral injury. I see this virtue as a basis for an active form of care for others and the self that resists temptations to refer to this objection.
Democracy is anchored by communication, grounded in a commitment to factual truth. This is an ideal historically captured by the ancient Athenian concept of parrhesia (frankness) and, in contemporary deliberative theory, by sincerity. This essay argues that the US far right has hijacked this democratic ideal, weaponizing it to create a post-truth environment and fuel a form of demagogic propaganda. The essay traces the historical evolution of the truth-telling ideal, noting how sincerity can morph into an antirhetorical style of “hyper-sincerity,” which performs shamelessness for a citizenry sidelined by massive economic inequality and corporate power. Drawing on Jason Stanley’s work, the essay then argues that this rhetorical style has become a form of fascist demagoguery, a rhetorical style that poses a threat to the very possibility of democratic politics. The final section explores the possibilities for irony as an antidote to hyper-sincerity. It reveals that the far right has also hijacked irony to create a mode of “fascist irony.” The paper concludes by calling for a “civic irony” rooted in a commitment to democratic values.
The letters exchanged between Ignatius Sancho and Laurence Sterne in 1766 have encountered considerable attention, as have those passages in Sterne’s works that seemingly engage with antislavery discourse. Some critics suggest these passages fail to address slavery directly; Sterne, in turn, has been viewed as readily capitalizing on his connection with Sancho to promote a philanthropic image that his writings do not support, and even to exploit it for financial gain. This article suggests a recalibration, partly based on the chronology of this exchange and its first public appearance in 1775. It argues that a richer understanding of Sancho’s and Sterne’s reception histories, and especially the role played by the eighteenth-century press in recirculating reviews of and excerpts from this exchange, helps to establish a more nuanced approach toward how the public image and the texts of both writers were subsequently incorporated into antislavery and Abolitionist debates.